Otto Orlean Yang

Professor, Medicine, University of California Los Angeles

Professor, MIMG, University of California Los Angeles

UC Profile

Education and Training

Harvard UniversityPost-Doc06/1997Immunology and Virology
Harvard University Medical School-Massachusetts General HospitalFellowship06/1997Infectious Diseases
New York University-Bellevue HospitalResidency06/1993Internal Medicine
Brown University Medical SchoolMD06/1990Medicine
Brown UniversityScB06/1987Human Biology

Publications

  1. Lee MJ, de Los Rios Kobara I, Barnard TR, Vales Torres X, Tobin NH, Ferbas KG, Rimoin AW, Yang OO, Aldrovandi GM, Wilk AJ, Fulcher JA, Blish CA. NK Cell-Monocyte Cross-talk Underlies NK Cell Activation in Severe COVID-19.. Journal of immunology (Baltimore, Md. : 1950), 2024.
  2. Gaylis NB, Yang OO. Understanding immune dysregulation in post-acute sequelae of COVID-19 (PASC) - The hunt for effective treatments.. The Journal of infection, 2024.
  3. Paules CI, Wang J, Tomashek KM, Bonnett T, Singh K, Marconi VC, Davey RT, Lye DC, Dodd LE, Yang OO, Benson CA, Deye GA, Doernberg SB, Hynes NA, Grossberg R, Wolfe CR, Nayak SU, Short WR, Voell J, Potter GE, Rapaka RR. A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-2.. Annals of internal medicine, 2024.
  4. Mohammadi A, Chiang S, Li F, Wei F, Lau CS, Aziz M, Ibarrondo FJ, Fulcher JA, Yang OO, Chia D, Kim Y, Wong DTW. Direct Detection of 4-Dimensions of SARS-CoV-2: Infection (vRNA), Infectivity (Antigen), Binding Antibody, and Functional Neutralizing Antibody in Saliva.. Research square, 2023.
  5. Silva BJA, Krogstad PA, Teles RMB, Andrade PR, Rajfer J, Ferrini MG, Yang OO, Bloom BR, Modlin RL. IFN-γ-mediated control of SARS-CoV-2 infection through nitric oxide.. Frontiers in immunology, 2023.
  6. Li X, Habibipour S, Chou T, Yang OO. The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus.. Virus evolution, 2023.
  7. Li X, Habibipour S, Chou T, Yang OO. The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus.. ArXiv, 2023.
  8. Lichtenstein B, Zheng Y, Gjertson D, Ferbas KG, Rimoin AW, Yang OO, Aldrovandi GM, Schaenman JM, Reed EF, Fulcher JA. Vascular and Non-HLA autoantibody profiles in hospitalized patients with COVID-19.. Frontiers in immunology, 2023.
  9. Taus E, Shino MY, Ibarrondo FJ, Hausner MA, Hofmann C, Yang OO. Predominantly defective CD8+ T cell immunity to SARS-CoV-2 mRNA vaccination in lung transplant recipients.. Journal of translational medicine, 2023.
  10. Taus E, Hofmann C, Ibarrondo FJ, Gong LS, Hausner MA, Fulcher JA, Krogstad P, Kitchen SG, Ferbas KG, Tobin NH, Rimoin AW, Aldrovandi GM, Yang OO. Persistent memory despite rapid contraction of circulating T Cell responses to SARS-CoV-2 mRNA vaccination.. Frontiers in immunology, 2023.
  11. Cambou MC, Liu CM, Mok T, Fajardo-Martinez V, Paiola SG, Ibarrondo FJ, Kerin T, Fuller T, Tobin NH, Garcia G, Bhattacharya D, Aldrovandi GM, Arumugaswami V, Foo SS, Jung JU, Vasconcelos Z, Brasil P, Brendolin M, Yang OO, Rao R, Nielsen-Saines K. Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy.. The Journal of infectious diseases, 2023.
  12. Mu W, Rezek V, Martin H, Carrillo MA, Tomer S, Hamid P, Lizarraga MA, Tibbe TD, Yang OO, Jamieson BD, Kitchen SG, Zhen A. Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo.. JCI insight, 2022.
  13. Recknor C, Hansen SG, Gaylis NB, Tiwary M, Sacha JB, Yang OO. Reply to Viel.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022.
  14. Gunawardana M, Webster S, Rivera S, Cortez JM, Breslin J, Pinales C, Buser C, Ibarrondo FJ, Yang OO, Bobardt M, Gallay PA, Adler AP, Ramirez CM, Anton PA, Baum MM. Early SARS-CoV-2 dynamics and immune responses in unvaccinated participants of an intensely sampled longitudinal surveillance study.. Communications medicine, 2022.
  15. Gaylis NB, Ritter A, Kelly SA, Pourhassan NZ, Tiwary M, Sacha JB, Hansen SG, Recknor C, Yang OO. Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022.
  16. Wang A, Li F, Chiang S, Fulcher J, Yang O, Wong D, Wei F. Machine learning prediction of COVID-19 severity levels from salivaomics data.. ArXiv, 2022.
  17. Wolfe CR, Tomashek KM, Patterson TF, Gomez CA, Marconi VC, Jain MK, Yang OO, Paules CI, Palacios GMR, Grossberg R, Harkins MS, Mularski RA, Erdmann N, Sandkovsky U, Almasri E, Pineda JR, Dretler AW, de Castilla DL, Branche AR, Park PK, Mehta AK, Short WR, McLellan SLF, Kline S, Iovine NM, El Sahly HM, Doernberg SB, Oh MD, Huprikar N, Hohmann E, Kelley CF, Holodniy M, Kim ES, Sweeney DA, Finberg RW, Grimes KA, Maves RC, Ko ER, Engemann JJ, Taylor BS, Ponce PO, Larson L, Melendez DP, Seibert AM, Rouphael NG, Strebe J, Clark JL, Julian KG, de Leon AP, Cardoso A, de Bono S, Atmar RL, Ganesan A, Ferreira JL, Green M, Makowski M, Bonnett T, Beresnev T, Ghazaryan V, Dempsey W, Nayak SU, Dodd LE, Beigel JH, Kalil AC, ACTT-4 Study Group. Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial.. The Lancet. Respiratory medicine, 2022.
  18. Tobin NH, Yang OO. Coronavirus Disease 2019 Vaccine Dosage in Children, Adolescents, and Young Adults: Is Less More?. Open forum infectious diseases, 2022.
  19. Paules CI, Gallagher SK, Rapaka RR, Davey RT, Doernberg SB, Grossberg R, Hynes NA, Ponce PO, Short WR, Voell J, Wang J, Yang OO, Wolfe CR, Lye DC, Dodd LE, Benson CA. Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022.
  20. Taus E, Hofmann C, Ibarrondo FJ, Hausner MA, Fulcher JA, Krogstad P, Ferbas KG, Tobin NH, Rimoin AW, Aldrovandi GM, Yang OO. Dominant CD8+ T Cell Nucleocapsid Targeting in SARS-CoV-2 Infection and Broad Spike Targeting From Vaccination.. Frontiers in immunology, 2022.
  21. Ibarrondo FJ, Hofmann C, Ali A, Ayoub P, Kohn DB, Yang OO. Previous Infection Combined with Vaccination Produces Neutralizing Antibodies with Potency against SARS-CoV-2 Variants.. mBio, 2021.
  22. Yang B, Fulcher JA, Ahn J, Berro M, Goodman-Meza D, Dhody K, Sacha JB, Naeim A, Yang OO. Clinical Characteristics and Outcomes of Coronavirus Disease 2019 Patients Who Received Compassionate-Use Leronlimab.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021.
  23. Gray AN, Martin-Blais R, Tobin NH, Wang Y, Brooker SL, Li F, Gadoth A, Elliott J, Faure-Kumar E, Halbrook M, Hofmann C, Kashani S, Kazan C, Yang OO, Fulcher JA, Grovit-Ferbas K, Rimoin AW, Aldrovandi GM. Humoral responses to SARS-CoV-2 mRNA vaccines: Role of past infection.. PloS one, 2021.
  24. Foo SS, Cambou MC, Mok T, Fajardo VM, Jung KL, Fuller T, Chen W, Kerin T, Mei J, Bhattacharya D, Choi Y, Wu X, Xia T, Shin WJ, Cranston J, Aldrovandi G, Tobin N, Contreras D, Ibarrondo FJ, Yang O, Yang S, Garner O, Cortado R, Bryson Y, Janzen C, Ghosh S, Devaskar S, Asilnejad B, Moreira ME, Vasconcelos Z, Soni PR, Gibson LC, Brasil P, Comhair SAA, Arumugaswami V, Erzurum SC, Rao R, Jung JU, Nielsen-Saines K. The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2.. Cell reports. Medicine, 2021.
  25. Balamurugan A, Ng HL, Yang OO. Correction for Balamurugan et al., "Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones".. Journal of virology, 2021.
  26. Xiao J, Bhondoekhan F, Seaberg EC, Yang O, Stosor V, Margolick JB, Yolken RH, Viscidi RP. Serological Responses to Toxoplasma gondii and Matrix Antigen 1 Predict the Risk of Subsequent Toxoplasmic Encephalitis in People Living With Human Immunodeficiency Virus (HIV).. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021.
  27. Zhen A, Carrillo MA, Mu W, Rezek V, Martin H, Hamid P, Chen ISY, Yang OO, Zack JA, Kitchen SG. Correction: Robust CAR-T memory formation and function via hematopoietic stem cell delivery.. PLoS pathogens, 2021.
  28. Bansal A, Gehre MN, Qin K, Sterrett S, Ali A, Dang Y, Abraham S, Costanzo MC, Venegas LA, Tang J, Manjunath N, Brockman MA, Yang OO, Kan-Mitchell J, Goepfert PA. HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection.. The Journal of clinical investigation, 2021.
  29. Gunawardana M, Breslin J, Cortez JM, Rivera S, Webster S, Ibarrondo FJ, Yang OO, Pyles RB, Ramirez CM, Adler AP, Anton PA, Baum MM. Longitudinal COVID-19 Surveillance and Characterization in the Workplace with Public Health and Diagnostic Endpoints.. mSphere, 2021.
  30. Kim JY, Lei Z, Maienschein-Cline M, Chlipala GE, Balamurugan A, McDiarmid SV, Azari K, Yang OO. Longitudinal Analysis of the T-cell Receptor Repertoire in Graft-infiltrating Lymphocytes Following Hand Transplantation.. Transplantation, 2021.
  31. Ibarrondo FJ, Hofmann C, Fulcher JA, Goodman-Meza D, Mu W, Hausner MA, Ali A, Balamurugan A, Taus E, Elliott J, Krogstad P, Tobin NH, Ferbas KG, Kitchen SG, Aldrovandi GM, Rimoin AW, Yang OO. Primary, Recall, and Decay Kinetics of SARS-CoV-2 Vaccine Antibody Responses.. ACS nano, 2021.
  32. Zhen A, Carrillo MA, Mu W, Rezek V, Martin H, Hamid P, Chen ISY, Yang OO, Zack JA, Kitchen SG. Robust CAR-T memory formation and function via hematopoietic stem cell delivery.. PLoS pathogens, 2021.
  33. Yang OO, Ibarrondo FJ. Loss of Anti-SARS-CoV-2 Antibodies in Mild Covid-19. Reply.. The New England journal of medicine, 2020.
  34. Ali A, Chiuppesi F, Nguyen M, Hausner MA, Nguyen J, Kha M, Iniguez A, Wussow F, Diamond DJ, Yang OO. Chimeric Antigen Receptors Targeting Human Cytomegalovirus.. The Journal of infectious diseases, 2020.
  35. Ibarrondo FJ, Fulcher JA, Goodman-Meza D, Elliott J, Hofmann C, Hausner MA, Ferbas KG, Tobin NH, Aldrovandi GM, Yang OO. Rapid Decay of Anti-SARS-CoV-2 Antibodies in Persons with Mild Covid-19.. The New England journal of medicine, 2020.
  36. Brown TT, Moser C, Currier JS, Ribaudo HJ, Rothenberg J, Kelesidis T, Yang O, Dubé MP, Murphy RL, Stein JH, McComsey GA. Erratum to: Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir.. The Journal of infectious diseases, 2020.
  37. Ali A, Furler RL, Pedroza-Martins L, Colantonio AD, Anisman-Posner D, Bryson Y, Yang OO, Uittenbogaart CH. A Novel HIV-1 Nef Mutation in a Primary Pediatric Isolate Impairs MHC-Class I Downregulation and Cytopathicity.. AIDS research and human retroviruses, 2019.
  38. Grossman MA, Hofmann C, Ng HL, Yang OO. Suboptimal stimulation by weak agonist epitope variants does not drive dysfunction of HIV-1-specific cytotoxic T lymphocyte clones.. AIDS (London, England), 2019.
  39. Fulcher JA, Tamshen K, Wollenberg AL, Kickhoefer VA, Mrazek J, Elliott J, Ibarrondo FJ, Anton PA, Rome LH, Maynard HD, Deming T, Yang OO. Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection.. Bioconjugate chemistry, 2019.
  40. Mu W, Homann S, Hofmann C, Gorin A, Huynh D, Yang OO, Kelesidis T. A Flow Cytometric Method to Determine Transfection Efficiency.. Bio-protocol, 2019.
  41. Furler RL, Ali A, Yang OO, Nixon DF. Nef-induced differential gene expression in primary CD4+ T cells following infection with HIV-1 isolates.. Virus genes, 2019.
  42. Ali A, Ng HL, Blankson JN, Burton DR, Buckheit RW, Moldt B, Fulcher JA, Ibarrondo FJ, Anton PA, Yang OO. Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1.. The Journal of infectious diseases, 2018.
  43. Balamurugan A, Ng HL, Yang OO. Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones.. Journal of virology, 2018.
  44. Kim J, De La Cruz J, Lam K, Ng H, Daar ES, Balamurugan A, Yang OO. CD8+ Cytotoxic T Lymphocyte Responses and Viral Epitope Escape in Acute HIV-1 Infection.. Viral immunology, 2018.
  45. Kelesidis T, Moser CB, Johnston E, Stein JH, Dube MP, Yang OO, McComsey GA, Currier JS, Brown TT. Brief Report: Changes in Plasma RANKL-Osteoprotegerin in a Prospective, Randomized Clinical Trial of Initial Antiviral Therapy: A5260s.. Journal of acquired immune deficiency syndromes (1999), 2018.
  46. Ding K, Zhang X, Mrazek J, Kickhoefer VA, Lai M, Ng HL, Yang OO, Rome LH, Zhou ZH. Solution Structures of Engineered Vault Particles.. Structure (London, England : 1993), 2018.
  47. Du Y, Zhang TH, Dai L, Zheng X, Gorin AM, Oishi J, Wu TT, Yoshizawa JM, Li X, Yang OO, Martinez-Maza O, Detels R, Sun R. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes.. mBio, 2017.
  48. Leitman EM, Willberg CB, Tsai MH, Chen H, Buus S, Chen F, Riddell L, Haas D, Fellay J, Goedert JJ, Piechocka-Trocha A, Walker BD, Martin J, Deeks S, Wolinsky SM, Martinson J, Martin M, Qi Y, Sáez-Cirión A, Yang OO, Matthews PC, Carrington M, Goulder PJR. HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.. Journal of virology, 2017.
  49. Weinstein M, Yang OO, Cohen AC. Were we prepared for PrEP? Five years of implementation.. AIDS (London, England), 2017.
  50. Homann S, Hofmann C, Gorin AM, Nguyen HCX, Huynh D, Hamid P, Maithel N, Yacoubian V, Mu W, Kossyvakis A, Sen Roy S, Yang OO, Kelesidis T. A novel rapid and reproducible flow cytometric method for optimization of transfection efficiency in cells.. PloS one, 2017.
  51. Dock J, Ramirez CM, Hultin L, Hausner MA, Hultin P, Elliott J, Yang OO, Anton PA, Jamieson BD, Effros RB. Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments.. PloS one, 2017.
  52. Gorin AM, Du Y, Liu FY, Zhang TH, Ng HL, Hofmann C, Cumberland WG, Sun R, Yang OO. HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.. PLoS pathogens, 2017.
  53. Balamurugan A, Claiborne D, Ng HL, Yang OO. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth.. Journal of virology, 2017.
  54. Fulcher JA, Romas L, Hoffman JC, Elliott J, Saunders T, Burgener AD, Anton PA, Yang OO. Highly Human Immunodeficiency Virus-Exposed Seronegative Men Have Lower Mucosal Innate Immune Reactivity.. AIDS research and human retroviruses, 2017.
  55. Yang OO, Cumberland WG, Escobar R, Liao D, Chew KW. Demographics and natural history of HIV-1-infected spontaneous controllers of viremia.. AIDS (London, England), 2017.
  56. Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, Ikeda A, Terrazas D, Fu PY, Yu A, Fernandez BC, Cooper AR, Engel B, Podsakoff G, Balamurugan A, Anderson S, Muul L, Jagadeesh GJ, Kapoor N, Tse J, Moore TB, Purdy K, Rishi R, Mohan K, Skoda-Smith S, Buchbinder D, Abraham RS, Scharenberg A, Yang OO, Cornetta K, Gjertson D, Hershfield M, Sokolic R, Candotti F, Kohn DB. Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.. The Journal of clinical investigation, 2017.
  57. Dock J, Hultin L, Hultin P, Elliot J, Yang OO, Anton PA, Jamieson BD, Effros RB. Human immune compartment comparisons: Optimization of proliferative assays for blood and gut T lymphocytes.. Journal of immunological methods, 2017.
  58. Kim JY, Kelesidis T, Yang OO. Detection of Donor-Derived Microparticles in the Peripheral Blood of a Hand Transplant Recipient During Rejection.. Transplantation direct, 2017.
  59. Schlimgen R, Howard J, Wooley D, Thompson M, Baden LR, Yang OO, Christiani DC, Mostoslavsky G, Diamond DV, Duane EG, Byers K, Winters T, Gelfand JA, Fujimoto G, Hudson TW, Vyas JM. Risks Associated With Lentiviral Vector Exposures and Prevention Strategies.. Journal of occupational and environmental medicine, 2016.
  60. Kelesidis T, Jackson N, McComsey GA, Wang X, Elashoff D, Dube MP, Brown TT, Yang OO, Stein JH, Currier JS. Oxidized lipoproteins are associated with markers of inflammation and immune activation in HIV-1 infection.. AIDS (London, England), 2016.
  61. Zhang X, Lai M, Chang W, Yu I, Ding K, Mrazek J, Ng HL, Yang OO, Maslov DA, Zhou ZH. Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.. Nature communications, 2016.
  62. Kelesidis T, Tran TTT, Brown TT, Moser C, Ribaudo HJ, Dube MP, Yang OO, McComsey GA, Stein JH, Currier JS. Changes in plasma levels of oxidized lipoproteins and lipoprotein subfractions with atazanavir-, raltegravir-, darunavir-based initial antiviral therapy and associations with common carotid artery intima-media thickness: ACTG 5260s.. Antiviral therapy, 2016.
  63. Lake JE, Seang S, Kelesidis T, Currier JS, Yang OO. Telmisartan increases vascular reparative capacity in older HIV-infected adults: a pilot study.. HIV clinical trials, 2016.
  64. Yang OO, Currier JS. Reimann's "Habitual Hyperthermia" Responding to Hormone Therapy.. Open forum infectious diseases, 2016.
  65. Ali A, Kitchen SG, Chen ISY, Ng HL, Zack JA, Yang OO. HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies.. Journal of virology, 2016.
  66. Kelesidis T, Moser C, Stein JH, Brown TT, Tran TT, Ribaudo HJ, Dube MP, Yang OO, Currier JS, McComsey GA. Changes in Markers of T-Cell Senescence and Exhaustion With Atazanavir-, Raltegravir-, and Darunavir-Based Initial Antiviral Therapy: ACTG 5260s.. The Journal of infectious diseases, 2016.
  67. Aguilera-Sandoval CR, Yang OO, Jojic N, Lovato P, Chen DY, Boechat MI, Cooper P, Zuo J, Ramirez C, Belzer M, Church JA, Krogstad P. Supranormal thymic output up to 2 decades after HIV-1 infection.. AIDS (London, England), 2016.
  68. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Correction: Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand.. PloS one, 2015.
  69. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand.. PloS one, 2015.
  70. Zhen A, Kamata M, Rezek V, Rick J, Levin B, Kasparian S, Chen IS, Yang OO, Zack JA, Kitchen SG. HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.. Molecular therapy : the journal of the American Society of Gene Therapy, 2015.
  71. Shen X, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara RR, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK, Pavlakis GN, Pantaleo G, Korber BT, Montefiori DC, Tomaras GD. Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.. Journal of virology, 2015.
  72. Kamata M, Kim PY, Ng HL, Ringpis GE, Kranz E, Chan J, O'Connor S, Yang OO, Chen IS. Ectopic expression of anti-HIV-1 shRNAs protects CD8(+) T cells modified with CD4ζ CAR from HIV-1 infection and alleviates impairment of cell proliferation.. Biochemical and biophysical research communications, 2015.
  73. Brown TT, Moser C, Currier JS, Ribaudo HJ, Rothenberg J, Kelesidis T, Yang O, Dubé MP, Murphy RL, Stein JH, McComsey GA. Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir.. The Journal of infectious diseases, 2015.
  74. Kelesidis T, Tran TT, Stein JH, Brown TT, Moser C, Ribaudo HJ, Dube MP, Murphy R, Yang OO, Currier JS, McComsey GA. Changes in Inflammation and Immune Activation With Atazanavir-, Raltegravir-, Darunavir-Based Initial Antiviral Therapy: ACTG 5260s.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015.
  75. Preza GC, Yang OO, Elliott J, Anton PA, Ochoa MT. T lymphocyte density and distribution in human colorectal mucosa, and inefficiency of current cell isolation protocols.. PloS one, 2015.
  76. D'Souza MP, Yang OO. Adenovirus vectors as HIV-1 vaccines: where are we? What next?. AIDS (London, England), 2015.
  77. Yang OO, Ali A, Kasahara N, Faure-Kumar E, Bae JY, Picker LJ, Park H. Short conserved sequences of HIV-1 are highly immunogenic and shift immunodominance.. Journal of virology, 2014.
  78. Kelesidis T, Roberts CK, Huynh D, Martínez-Maza O, Currier JS, Reddy ST, Yang OO. A high throughput biochemical fluorometric method for measuring lipid peroxidation in HDL.. PloS one, 2014.
  79. Hoffman JC, Anton PA, Baldwin GC, Elliott J, Anisman-Posner D, Tanner K, Grogan T, Elashoff D, Sugar C, Yang OO, Hoffman RM. Seminal plasma HIV-1 RNA concentration is strongly associated with altered levels of seminal plasma interferon-γ, interleukin-17, and interleukin-5.. AIDS research and human retroviruses, 2014.
  80. Yang OO, Kelesidis T, Cordova R, Khanlou H. Immunomodulation of antiretroviral drug-suppressed chronic HIV-1 infection in an oral probiotic double-blind placebo-controlled trial.. AIDS research and human retroviruses, 2014.
  81. Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang OO, Crooks GM. Engineering the human thymic microenvironment to support thymopoiesis in vivo.. Stem cells (Dayton, Ohio), 2014.
  82. Al-Mawsawi LQ, Wu NC, De La Cruz J, Shi VC, Wu TT, Daar ES, Lewis MJ, Yang OO, Sun R. Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing.. AIDS research and human retroviruses, 2014.
  83. Kelesidis T, Currier JS, Yang OO, Brown TT. Role of RANKL-RANK/osteoprotegerin pathway in cardiovascular and bone disease associated with HIV infection.. AIDS reviews, 2014.
  84. Wu NC, De La Cruz J, Al-Mawsawi LQ, Olson CA, Qi H, Luan HH, Nguyen N, Du Y, Le S, Wu TT, Li X, Lewis MJ, Yang OO, Sun R. HIV-1 quasispecies delineation by tag linkage deep sequencing.. PloS one, 2014.
  85. De La Cruz J, Vollbrecht T, Frohnen P, Ng HL, Daar ES, Yang OO, Lewis MJ. Ineffectual targeting of HIV-1 Nef by cytotoxic T lymphocytes in acute infection results in no functional impairment or viremia reduction.. Journal of virology, 2014.
  86. Yang OO, Ibarrondo FJ, Price C, Hultin LE, Elliott J, Hultin PM, Shih R, Hausner MA, Ng HL, Hoffman J, Jamieson BD, Anton PA. Differential blood and mucosal immune responses against an HIV-1 vaccine administered via inguinal or deltoid injection.. PloS one, 2014.
  87. Zanni MV, Kelesidis T, Fitzgerald ML, Lo J, Abbara S, Wai B, Marmarelis E, Hernandez NJ, Yang OO, Currier JS, Grinspoon SK. HDL redox activity is increased in HIV-infected men in association with macrophage activation and non-calcified coronary atherosclerotic plaque.. Antiviral therapy, 2014.
  88. Preza GC, Tanner K, Elliott J, Yang OO, Anton PA, Ochoa MT. Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages.. AIDS research and human retroviruses, 2013.
  89. Yeghiazarian L, Cumberland WG, Yang OO. A stochastic multi-scale model of HIV-1 transmission for decision-making: application to a MSM population.. PloS one, 2013.
  90. Ibarrondo FJ, Yang OO, Chodon T, Avramis E, Lee Y, Sazegar H, Jalil J, Chmielowski B, Koya RC, Schmid I, Gomez-Navarro J, Jamieson BD, Ribas A, Comin-Anduix B. Natural killer T cells in advanced melanoma patients treated with tremelimumab.. PloS one, 2013.
  91. Lewis MJ, Frohnen P, Ibarrondo FJ, Reed D, Iyer V, Ng HL, Elliott J, Yang OO, Anton P. HIV-1 Nef sequence and functional compartmentalization in the gut is not due to differential cytotoxic T lymphocyte selective pressure.. PloS one, 2013.
  92. Roberts CK, Katiraie M, Croymans DM, Yang OO, Kelesidis T. Untrained young men have dysfunctional HDL compared with strength-trained men irrespective of body weight status.. Journal of applied physiology (Bethesda, Md. : 1985), 2013.
  93. Balamurugan A, Ali A, Boucau J, Le Gall S, Ng HL, Yang OO. HIV-1 gag cytotoxic T lymphocyte epitopes vary in presentation kinetics relative to HLA class I downregulation.. Journal of virology, 2013.
  94. Vatakis DN, Arumugam B, Kim SG, Bristol G, Yang O, Zack JA. Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression.. Molecular therapy : the journal of the American Society of Gene Therapy, 2013.
  95. Kelesidis T, Yang OO, Kendall MA, Hodis HN, Currier JS. Dysfunctional HDL and progression of atherosclerosis in HIV-1-infected and -uninfected adults.. Lipids in health and disease, 2013.
  96. Bhattacharya D, Lewis MJ, Lassmann B, Phan T, Knecht G, Bickel M, Yang OO. Combination of allele-specific detection techniques to quantify minority resistance variants in hepatitis B infection: a novel approach.. Journal of virological methods, 2013.
  97. Kelesidis T, Kendall MA, Yang OO, Hodis H, Currier JS. Perturbations of circulating levels of RANKL-osteoprotegerin axis in relation to lipids and progression of atherosclerosis in HIV-infected and -uninfected adults: ACTG NWCS 332/A5078 Study.. AIDS research and human retroviruses, 2013.
  98. Liu Y, Du J, Yan M, Lau MY, Hu J, Han H, Yang OO, Liang S, Wei W, Wang H, Li J, Zhu X, Shi L, Chen W, Ji C, Lu Y. Biomimetic enzyme nanocomplexes and their use as antidotes and preventive measures for alcohol intoxication.. Nature nanotechnology, 2013.
  99. Kløverpris HN, Payne RP, Sacha JB, Rasaiyaah JT, Chen F, Takiguchi M, Yang OO, Towers GJ, Goulder P, Prado JG. Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells.. Journal of virology, 2012.
  100. Kelesidis T, Kendall MA, Yang OO, Hodis HN, Currier JS. Biomarkers of microbial translocation and macrophage activation: association with progression of subclinical atherosclerosis in HIV-1 infection.. The Journal of infectious diseases, 2012.
  101. Wick WD, Yang OO. Biologically-directed modeling reflects cytolytic clearance of SIV-infected cells in vivo in macaques.. PloS one, 2012.
  102. Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.. Blood, 2012.
  103. Brennan CA, Ibarrondo FJ, Sugar CA, Hausner MA, Shih R, Ng HL, Detels R, Margolick JB, Rinaldo CR, Phair J, Jacobson LP, Yang OO, Jamieson BD. Early HLA-B*57-restricted CD8+ T lymphocyte responses predict HIV-1 disease progression.. Journal of virology, 2012.
  104. Kelesidis T, Reddy ST, Huynh D, Meriwether D, Fogelman AM, Navab M, Yang OO. Effects of lipid-probe interactions in biochemical fluorometric methods that assess HDL redox activity.. Lipids in health and disease, 2012.
  105. Chen DY, Balamurugan A, Ng HL, Cumberland WG, Yang OO. Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytes.. Blood, 2012.
  106. Lewis MJ, Lee P, Ng HL, Yang OO. Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo.. Journal of virology, 2012.
  107. Lewis MJ, Dagarag M, Khan B, Ali A, Yang OO. Partial escape of HIV-1 from cytotoxic T lymphocytes during chronic infection.. Journal of virology, 2012.
  108. Gossett DR, Tse HT, Lee SA, Ying Y, Lindgren AG, Yang OO, Rao J, Clark AT, Di Carlo D. Hydrodynamic stretching of single cells for large population mechanical phenotyping.. Proceedings of the National Academy of Sciences of the United States of America, 2012.
  109. Kitchen SG, Levin BR, Bristol G, Rezek V, Kim S, Aguilera-Sandoval C, Balamurugan A, Yang OO, Zack JA. In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.. PLoS pathogens, 2012.
  110. Mothe B, Llano A, Ibarrondo J, Daniels M, Miranda C, Zamarreño J, Bach V, Zuniga R, Pérez-Álvarez S, Berger CT, Puertas MC, Martinez-Picado J, Rolland M, Farfan M, Szinger JJ, Hildebrand WH, Yang OO, Sanchez-Merino V, Brumme CJ, Brumme ZL, Heckerman D, Allen TM, Mullins JI, Gómez G, Goulder PJ, Walker BD, Gatell JM, Clotet B, Korber BT, Sanchez J, Brander C. Definition of the viral targets of protective HIV-1-specific T cell responses.. Journal of translational medicine, 2011.
  111. Zuo J, Suen J, Wong A, Lewis M, Ayub A, Belzer M, Church J, Yang OO, Krogstad P. Functional analysis of HIV type 1 Nef gene variants from adolescent and adult survivors of perinatal infection.. AIDS research and human retroviruses, 2011.
  112. Kelesidis T, Currier JS, Huynh D, Meriwether D, Charles-Schoeman C, Reddy ST, Fogelman AM, Navab M, Yang OO. A biochemical fluorometric method for assessing the oxidative properties of HDL.. Journal of lipid research, 2011.
  113. Kelesidis T, Humphries R, Ward K, Lewinski MA, Yang OO. Combination therapy with daptomycin, linezolid, and rifampin as treatment option for MRSA meningitis and bacteremia.. Diagnostic microbiology and infectious disease, 2011.
  114. Yang OO, Lewis MJ, Reed EF, Gjertson DW, Kalilani-Phiri L, Mkandawire J, Helleringer S, Kohler HP. Human leukocyte antigen class I haplotypes of human immunodeficiency virus-1-infected persons on Likoma Island, Malawi.. Human immunology, 2011.
  115. Kelesidis T, Yang OO, Currier JS, Navab K, Fogelman AM, Navab M. HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL.. Lipids in health and disease, 2011.
  116. Chen DY, Balamurugan A, Ng HL, Yang OO. Antiviral activity of human immunodeficiency virus type 1 Gag-specific cytotoxic T lymphocyte targeting is not necessarily intrinsically superior to envelope targeting.. Journal of virology, 2010.
  117. Yang OO, Daar ES, Ng HL, Shih R, Jamieson BD. Increasing CTL targeting of conserved sequences during early HIV-1 infection is correlated to decreasing viremia.. AIDS research and human retroviruses, 2010.
  118. Bennett MS, Joseph A, Ng HL, Goldstein H, Yang OO. Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes.. AIDS (London, England), 2010.
  119. International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.. Science (New York, N.Y.), 2010.
  120. Balamurugan A, Ng HL, Yang OO. Rapid T cell receptor delineation reveals clonal expansion limitation of the magnitude of the HIV-1-specific CD8+ T cell response.. Journal of immunology (Baltimore, Md. : 1950), 2010.
  121. Schaubert KL, Price DA, Salkowitz JR, Sewell AK, Sidney J, Asher TE, Blondelle SE, Adams S, Marincola FM, Joseph A, Sette A, Douek DC, Ayyavoo V, Storkus W, Leung MY, Ng HL, Yang OO, Goldstein H, Wilson DB, Kan-Mitchell J. Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes.. European journal of immunology, 2010.
  122. Gregson AL, Hoji A, Palchevskiy V, Hu S, Weigt SS, Liao E, Derhovanessian A, Saggar R, Song S, Elashoff R, Yang OO, Belperio JA. Protection against bronchiolitis obliterans syndrome is associated with allograft CCR7+ CD45RA- T regulatory cells.. PloS one, 2010.
  123. Yang OO, Kelesidis T. Interleukin-2-unresponsive immune defects in good syndrome: Letter to the Editor.. Clinical immunology (Orlando, Fla.), 2010.
  124. Kelesidis T, Yang O. Good's syndrome remains a mystery after 55 years: A systematic review of the scientific evidence.. Clinical immunology (Orlando, Fla.), 2010.
  125. Shimizu S, Hong P, Arumugam B, Pokomo L, Boyer J, Koizumi N, Kittipongdaja P, Chen A, Bristol G, Galic Z, Zack JA, Yang O, Chen IS, Lee B, An DS. A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.. Blood, 2009.
  126. Kitchen SG, Bennett M, Galic Z, Kim J, Xu Q, Young A, Lieberman A, Joseph A, Goldstein H, Ng H, Yang O, Zack JA. Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.. PloS one, 2009.
  127. Yang OO. Candidate vaccine sequences to represent intra- and inter-clade HIV-1 variation.. PloS one, 2009.
  128. Ali A, Realegeno S, Yang OO, Lewis MJ. Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection.. Journal of virological methods, 2009.
  129. Cruz Jde L, Ali A, Ng HL, Yang OO. Disruption of an env tyrosine-dependent sorting signal does not affect susceptibility of HIV-1 to cytotoxic T lymphocytes.. AIDS (London, England), 2009.
  130. Miller JP, Geng Y, Ng HL, Yang OO, Krogstad P. Packaging limits and stability of HIV-1 sequences in a coxsackievirus B vector.. Vaccine, 2009.
  131. Yang OO. Assessing the antiviral activity of HIV-1-specific cytotoxic T lymphocytes.. Methods in molecular biology (Clifton, N.J.), 2009.
  132. Galic Z, Kitchen SG, Subramanian A, Bristol G, Marsden MD, Balamurugan A, Kacena A, Yang O, Zack JA. Generation of T lineage cells from human embryonic stem cells in a feeder free system.. Stem cells (Dayton, Ohio), 2009.
  133. Wick WD, Gilbert PB, Yang OO. Predicting the impact of blocking human immunodeficiency virus type 1 Nef in vivo.. Journal of virology, 2008.
  134. Fauce SR, Jamieson BD, Chin AC, Mitsuyasu RT, Parish ST, Ng HL, Kitchen CM, Yang OO, Harley CB, Effros RB. Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.. Journal of immunology (Baltimore, Md. : 1950), 2008.
  135. Hoji A, Coro A, Ng HL, Jamieson BD, Yang OO. Proliferation and foxp3 expression in virus-specific memory CD8+ T lymphocytes.. AIDS research and human retroviruses, 2008.
  136. Anton PA, Ibarrondo FJ, Boscardin WJ, Zhou Y, Schwartz EJ, Ng HL, Hausner MA, Shih R, Elliott J, Hultin PM, Hultin LE, Price C, Fuerst M, Adler A, Wong JT, Yang OO, Jamieson BD. Differential immunogenicity of vaccinia and HIV-1 components of a human recombinant vaccine in mucosal and blood compartments.. Vaccine, 2008.
  137. Gregson AL, Hoji A, Saggar R, Ross DJ, Kubak BM, Jamieson BD, Weigt SS, Lynch JP, Ardehali A, Belperio JA, Yang OO. Bronchoalveolar immunologic profile of acute human lung transplant allograft rejection.. Transplantation, 2008.
  138. Lewis MJ, Balamurugan A, Ohno A, Kilpatrick S, Ng HL, Yang OO. Functional adaptation of Nef to the immune milieu of HIV-1 infection in vivo.. Journal of immunology (Baltimore, Md. : 1950), 2008.
  139. Yang OO. Retracing our STEP towards a successful CTL-based HIV-1 vaccine.. Vaccine, 2008.
  140. Bennett MS, Ng HL, Ali A, Yang OO. Cross-clade detection of HIV-1-specific cytotoxic T lymphocytes does not reflect cross-clade antiviral activity.. The Journal of infectious diseases, 2008.
  141. Yang OO. Aiming for successful vaccine-induced HIV-1-specific cytotoxic T lymphocytes.. AIDS (London, England), 2008.
  142. Balamurugan A, Lewis MJ, Kitchen CM, Robertson MN, Shiver JW, Daar ES, Pitt J, Ali A, Ng HL, Currier JS, Yang OO. Primary human immunodeficiency virus type 1 (HIV-1) infection during HIV-1 Gag vaccination.. Journal of virology, 2008.
  143. LeBreton M, Yang O, Tamoufe U, Mpoudi-Ngole E, Torimiro JN, Djoko CF, Carr JK, Tassy Prosser A, Rimoin AW, Birx DL, Burke DS, Wolfe ND. Exposure to wild primates among HIV-infected persons.. Emerging infectious diseases, 2007.
  144. Fauce SR, Yang OO, Effros RB. Autologous CD4/CD8 co-culture assay: a physiologically-relevant composite measure of CD8+ T lymphocyte function in HIV-infected persons.. Journal of immunological methods, 2007.
  145. Yang OO, Wilson SB, Hultin LE, Detels R, Hultin PM, Ibarrondo FJ, Jamieson BD. Delayed reconstitution of CD4+ iNKT cells after effective HIV type 1 therapy.. AIDS research and human retroviruses, 2007.
  146. Schaubert KL, Price DA, Frahm N, Li J, Ng HL, Joseph A, Paul E, Majumder B, Ayyavoo V, Gostick E, Adams S, Marincola FM, Sewell AK, Altfeld M, Brenchley JM, Douek DC, Yang OO, Brander C, Goldstein H, Kan-Mitchell J. Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope.. Journal of immunology (Baltimore, Md. : 1950), 2007.
  147. Ching N, Yang OO, Deville JG, Nielsen-Saines K, Ank BJ, Sim MS, Bryson YJ. Pediatric HIV-1-specific cytotoxic T-lymphocyte responses suggesting ongoing viral replication despite combination antiretroviral therapy.. Pediatric research, 2007.
  148. Wang Q, Wang W, Zheng J, Tabibian S, Xie Y, Song J, Waring AJ, Chiu R, Yang OO, Chen IS, Lehrer RI, Pang S. Paradoxical effects of two theta-defensins on HIV type 1 infection.. AIDS research and human retroviruses, 2007.
  149. Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, Bean AT, Lee W, Burwitz BJ, Stephany JJ, Loffredo JT, Allison DB, Adnan S, Hoji A, Wilson NA, Friedrich TC, Lifson JD, Yang OO, Watkins DI. Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression.. Journal of immunology (Baltimore, Md. : 1950), 2007.
  150. Bennett MS, Ng HL, Dagarag M, Ali A, Yang OO. Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells.. Journal of virology, 2007.
  151. Zheng J, Xie Y, Campbell R, Song J, Wang RQ, Chiu R, Berenson J, Razi M, Massachi S, Yang OO, Chen IS, Pang S. gp120-independent HIV infection of cells derived from the female reproductive tract, brain, and colon.. Journal of acquired immune deficiency syndromes (1999), 2006.
  152. Adnan S, Balamurugan A, Trocha A, Bennett MS, Ng HL, Ali A, Brander C, Yang OO. Nef interference with HIV-1-specific CTL antiviral activity is epitope specific.. Blood, 2006.
  153. Kan-Mitchell J, Bajcz M, Schaubert KL, Price DA, Brenchley JM, Asher TE, Douek DC, Ng HL, Yang OO, Rinaldo CR, Benito JM, Bisikirska B, Hegde R, Marincola FM, Boggiano C, Wilson D, Abrams J, Blondelle SE, Wilson DB. Degeneracy and repertoire of the human HIV-1 Gag p17(77-85) CTL response.. Journal of immunology (Baltimore, Md. : 1950), 2006.
  154. Cole AL, Yang OO, Warren AD, Waring AJ, Lehrer RI, Cole AM. HIV-1 adapts to a retrocyclin with cationic amino acid substitutions that reduce fusion efficiency of gp41.. Journal of immunology (Baltimore, Md. : 1950), 2006.
  155. Pedroza-Martins L, Boscardin WJ, Anisman-Posner DJ, Redsar BN, Bryson YJ, Yang OO, Uittenbogaart CH. Interferon-gamma decreases replication of primary R5 HIV-1 isolates in thymocytes.. AIDS (London, England), 2006.
  156. Jamieson BD, Ibarrondo FJ, Wong JT, Hausner MA, Ng HL, Fuerst M, Price C, Shih R, Elliott J, Hultin PM, Hultin LE, Anton PA, Yang OO. Transience of vaccine-induced HIV-1-specific CTL and definition of vaccine "response".. Vaccine, 2006.
  157. Zheng J, Xie Y, Campbell R, Song J, Massachi S, Razi M, Chiu R, Berenson J, Yang OO, Chen IS, Pang S. Involvement of claudin-7 in HIV infection of CD4(-) cells.. Retrovirology, 2005.
  158. Yang OO, Church J, Kitchen CM, Kilpatrick R, Ali A, Geng Y, Killian MS, Sabado RL, Ng H, Suen J, Bryson Y, Jamieson BD, Krogstad P. Genetic and stochastic influences on the interaction of human immunodeficiency virus type 1 and cytotoxic T lymphocytes in identical twins.. Journal of virology, 2005.
  159. Ali A, Yang OO. A novel small reporter gene and HIV-1 fitness assay.. Journal of virological methods, 2005.
  160. Ali A, Ng HL, Dagarag MD, Yang OO. Evasion of cytotoxic T lymphocytes is a functional constraint maintaining HIV-1 Nef expression.. European journal of immunology, 2005.
  161. Wick WD, Yang OO, Corey L, Self SG. How many human immunodeficiency virus type 1-infected target cells can a cytotoxic T-lymphocyte kill?. Journal of virology, 2005.
  162. Yang OO, Ferbas JJ, Hausner MA, Hultin LE, Hultin PM, McFadden D, Sawicki M, Detels R, Majchrowicz M, Matud JL, Giorgi JV, Jamieson BD. Effects of HIV-1 infection on lymphocyte phenotypes in blood versus lymph nodes.. Journal of acquired immune deficiency syndromes (1999), 2005.
  163. Killian MS, Sabado RL, Kilpatrick S, Hausner MA, Jamieson BD, Yang OO. Clonal breadth of the HIV-1-specific T-cell receptor repertoire in vivo as determined by subtractive analysis.. AIDS (London, England), 2005.
  164. Ibarrondo FJ, Anton PA, Fuerst M, Ng HL, Wong JT, Matud J, Elliott J, Shih R, Hausner MA, Price C, Hultin LE, Hultin PM, Jamieson BD, Yang OO. Parallel human immunodeficiency virus type 1-specific CD8+ T-lymphocyte responses in blood and mucosa during chronic infection.. Journal of virology, 2005.
  165. Yang OO, Lin H, Dagarag M, Ng HL, Effros RB, Uittenbogaart CH. Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes.. Virology, 2005.
  166. Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains.. Journal of virology, 2005.
  167. Zheng J, Yang OO, Xie Y, Campbell R, Chen IS, Pang S. Ethanol stimulation of HIV infection of oral epithelial cells.. Journal of acquired immune deficiency syndromes (1999), 2004.
  168. Sabado RL, Kilpatrick S, Ali A, Dagarag M, Ng HL, Cao H, Yang OO. Detection of HIV-1-specific CTL responses in Clade B infection with Clade C Peptides and not Clade B consensus peptides.. Journal of immunological methods, 2004.
  169. Norris PJ, Moffett HF, Yang OO, Kaufmann DE, Clark MJ, Addo MM, Rosenberg ES. Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.. Journal of virology, 2004.
  170. Lubong R, Ng HL, Uittenbogaart CH, Yang OO. Culturing of HIV-1-specific cytotoxic T lymphocytes with interleukin-7 and interleukin-15.. Virology, 2004.
  171. Yang OO. CTL ontogeny and viral escape: implications for HIV-1 vaccine design.. Trends in immunology, 2004.
  172. Killian MS, Monteiro J, Matud J, Hultin LE, Hausner MA, Yang OO, Gregersen PK, Detels R, Giorgi JV, Jamieson BD. Persistent alterations in the T-cell repertoires of HIV-1-infected and at-risk uninfected men.. AIDS (London, England), 2004.
  173. Ali A, Lubong R, Ng H, Brooks DG, Zack JA, Yang OO. Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.. Journal of virology, 2004.
  174. Jamieson BD, Yang OO, Hultin L, Hausner MA, Hultin P, Matud J, Kunstman K, Killian S, Altman J, Kommander K, Korber B, Giorgi J, Wolinsky S. Epitope escape mutation and decay of human immunodeficiency virus type 1-specific CTL responses.. Journal of immunology (Baltimore, Md. : 1950), 2003.
  175. Ali A, Pillai S, Ng H, Lubong R, Richman DD, Jamieson BD, Ding Y, McElrath MJ, Guatelli JC, Yang OO. Broadly increased sensitivity to cytotoxic T lymphocytes resulting from Nef epitope escape mutations.. Journal of immunology (Baltimore, Md. : 1950), 2003.
  176. Yang OO, Sarkis PT, Trocha A, Kalams SA, Johnson RP, Walker BD. Impacts of avidity and specificity on the antiviral efficiency of HIV-1-specific CTL.. Journal of immunology (Baltimore, Md. : 1950), 2003.
  177. Münk C, Wei G, Yang OO, Waring AJ, Wang W, Hong T, Lehrer RI, Landau NR, Cole AM. The theta-defensin, retrocyclin, inhibits HIV-1 entry.. AIDS research and human retroviruses, 2003.
  178. Shacklett BL, Yang O, Hausner MA, Elliott J, Hultin L, Price C, Fuerst M, Matud J, Hultin P, Cox C, Ibarrondo J, Wong JT, Nixon DF, Anton PA, Jamieson BD. Optimization of methods to assess human mucosal T-cell responses to HIV infection.. Journal of immunological methods, 2003.
  179. Ali A, Jamieson BD, Yang OO. Half-genome human immunodeficiency virus type 1 constructs for rapid production of reporter viruses.. Journal of virological methods, 2003.
  180. Yang OO, Sarkis PT, Ali A, Harlow JD, Brander C, Kalams SA, Walker BD. Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes.. The Journal of experimental medicine, 2003.
  181. Dagarag M, Ng H, Lubong R, Effros RB, Yang OO. Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.. Journal of virology, 2003.
  182. Severino ME, Sarkis PT, Walker BD, Yang OO. Chimeric immune receptor T cells bypass class I requirements and recognize multiple cell types relevant in HIV-1 infection.. Virology, 2003.
  183. Yang OO. Will we be able to 'spot' an effective HIV-1 vaccine?. Trends in immunology, 2003.
  184. Cole AM, Liao HI, Ganz T, Yang OO. Antibacterial activity of peptides derived from envelope glycoproteins of HIV-1.. FEBS letters, 2003.
  185. Yang OO, Boscardin WJ, Matud J, Hausner MA, Hultin LE, Hultin PM, Shih R, Ferbas J, Siegal FP, Shodell M, Shearer GM, Grene E, Carrington M, O'Brien S, Price CB, Detels R, Jamieson BD, Giorgi JV. Immunologic profile of highly exposed yet HIV type 1-seronegative men.. AIDS research and human retroviruses, 2002.
  186. Yang OO, Garcia-Zepeda EA, Walker BD, Luster AD. Monocyte chemoattractant protein-2 (CC chemokine ligand 8) inhibits replication of human immunodeficiency virus type 1 via CC chemokine receptor 5.. The Journal of infectious diseases, 2002.
  187. Cole AM, Hong T, Boo LM, Nguyen T, Zhao C, Bristol G, Zack JA, Waring AJ, Yang OO, Lehrer RI. Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.. Proceedings of the National Academy of Sciences of the United States of America, 2002.
  188. Yang OO, Nguyen PT, Kalams SA, Dorfman T, Göttlinger HG, Stewart S, Chen IS, Threlkeld S, Walker BD. Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes.. Journal of virology, 2002.
  189. Yang OO, Racke FK, Nguyen PT, Gausling R, Severino ME, Horton HF, Byrne MC, Strominger JL, Wilson SB. CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of V alpha 24J alpha Q T cells: a feedback mechanism for immune regulation.. Journal of immunology (Baltimore, Md. : 1950), 2000.