Biosciences at UCLA
Cores and Resources Serving UCLA
John Miao, Ph.D.

Email Address:
miao@physics.ucla.edu Work Address:
UCLA
Department of Physics & Astronomy
Box 951547
3-108 Knudsen
Los Angeles, CA 90095
UNITED STATES

Work Phone Number:
(310) 206-2645

Web Address:
http://www.cnsi.ucla.edu/arr/personnel-papers?personnel_id=113666
Web Address:
http://www.physics.ucla.edu/research/imaging/index.htm?
Web Address:
http://www.physics.ucla.edu/research/imaging/members/john_miao/index.htm

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Department / Division Affiliations
Director, X-Ray Diffraction & Imaging Lab
Professor, Physics and Astronomy
Member, NanoBiotechnology and Biomaterials, California NanoSystems Institute
Research Interest:

My research interests lie in the interplay of physics, nanoscience and biology. I am particularly interested in developing new physical methods for quantitative imaging of nanoscale materials and biological specimens in three dimensions. I have played a major role in pioneering a three-dimensional imaging approach based upon the principle of using coherent diffraction in combination with a method of direct phase recovery called oversampling. I, together with my graduate students and postdocs, will continue to improve the spatial resolution of this imaging technique and pursue its applications in nanoscience and biology by using optical lasers, coherent X-rays and electrons.

Publications:

J. Miao, Y. Nishino, Y. Kohmura, B. Johnson, S.H. Risbud and T. Ishikawa. "Quantitative Image Reconstructive of GaN Quantum Dots from Oversampled Diffraction Intensities Alone". Phys. Rev. Lett. 2005; .
Miao, J Chapman, HN Kirz, J Sayre, D Hodgson, KO. "Taking X-ray diffraction to the limit: macromolecular structures from femtosecond X-ray pulses and diffraction microscopy of cells with synchrotron radiation". Annual review of biophysics and biomolecular structure. . 2004; 33: 157-76.
K. Robinson and J. Miao. "Three Dimensional X-ray Diffraction Microscopy". MRS Bulletin 2004; 29: 177-181 .
J. Miao, J. Amonette, Y. Nishino, T. Ishikawa and K. O. Hodgson. "Direct Determination of the Absolute Electron Density of Nanostructured and Disordered Materials at Sub-10 nm Resolution". Phys. Rev. 2003; B 68: 012201.
G.S. Edwards, R.H. Austin, F.E. Carroll, M.L. Copeland, M.E. Couprie, W.E.Gabella, R.F. Haglund, B.A. Hooper, M.S. Hutson, E.D. Jansen, K.M. Joos, D.P. Kiehart, I. Lindau, J. Miao, H.S. Pratisto, J.H. Shen, Y. Tokutake, L. van der Meer and Aihua Xie. "Free-electron-laser-based biophysical and biomedical instrumentation". Rev. Sci. Instru. 2003; 74: 3207-45.
Y. Nishino, J. Miao and T. Ishikawa. "Image Reconstruction of Nanostructured Non-Periodic Objects Only from Oversampled Hard X-ray Diffraction Intensities". Phys. Rev. B (Rapid Commun.) 2003; 68: 220101.
J. Miao, T. Ishikawa, E. H. Anderson and K. O. Hodgson. "Phase Retrieval of Diffraction Patterns from Non-Crystalline Samples". Phys. Rev. 2003; B 67: 174104.
Miao, J Hodgson, KO Ishikawa, T Larabell, CA LeGros, MA Nishino, Y Imaging whole Escherichia coli bacteria by using single-particle x-ray diffraction.. Proceedings of the National Academy of Sciences of the United States of America. . 2003; 100(1): 110-2.
J. Miao, T. Ohsuna, O. Terasaki, K. O. Hodgson and M. A. O'Keefe. "Atomic Resolution Three-Dimensional Electron Diffraction Microscopy". Phys. Rev. Lett. 2002; 89: 155502.
J. Miao, T. Ishikawa, B. Johnson, E. H. Anderson, B. Lai and K. O. Hodgson. "High Resolution 3D X-ray Diffraction Microscopy". Phys. Rev. Lett. 2002; 89: 088303.