Publications

1. González VV, Zhang Y, Ashikyan SA, Rickard A, Yassine I, Romero-Sosa JL, Blaisdell AP, Izquierdo A. A special role for anterior cingulate cortex, but not orbitofrontal cortex or basolateral amygdala, in choices involving information.. Cerebral cortex (New York, N.Y. : 1991), 2024.
2. Aguirre CG, Woo JH, Romero-Sosa JL, Rivera ZM, Tejada AN, Munier JJ, Perez J, Goldfarb M, Das K, Gomez M, Ye T, Pannu J, Evans K, O'Neill PR, Spigelman I, Soltani A, Izquierdo A. Dissociable Contributions of Basolateral Amygdala and Ventrolateral Orbitofrontal Cortex to Flexible Learning Under Uncertainty.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024.
3. González VV, Ashikyan SA, Zhang Y, Rickard A, Yassine I, Romero-Sosa JL, Blaisdell AP, Izquierdo A. A special role for anterior cingulate cortex, but not orbitofrontal cortex or basolateral amygdala, in choices involving information.. bioRxiv : the preprint server for biology, 2023.
4. Ye T, Romero-Sosa JL, Rickard A, Aguirre CG, Wikenheiser AM, Blair HT, Izquierdo A. Theta oscillations in anterior cingulate cortex and orbitofrontal cortex differentially modulate accuracy and speed in flexible reward learning.. Oxford open neuroscience, 2023.
5. Woo JH, Aguirre CG, Bari BA, Tsutsui KI, Grabenhorst F, Cohen JY, Schultz W, Izquierdo A, Soltani A. Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys.. Cognitive, affective & behavioral neuroscience, 2023.
6. Chen Z, Blair GJ, Guo C, Zhou J, Romero-Sosa JL, Izquierdo A, Golshani P, Cong J, Aharoni D, Blair HT. A hardware system for real-time decoding of in vivo calcium imaging data.. eLife, 2023.
7. Sanabria F, Langdon A, Izquierdo A. Timing, neural timescales, and temporal cognition.. Behavioral neuroscience, 2022.
8. Gilbert S, Ibáñez C, Izquierdo A, Reiner O, Wang H. Introducing Oxford Open Neuroscience.. Oxford open neuroscience, 2022.
9. Nieto SJ, Grodin EN, Aguirre CG, Izquierdo A, Ray LA. Translational opportunities in animal and human models to study alcohol use disorder.. Translational psychiatry, 2021.
10. Rudebeck PH, Izquierdo A. Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021.
11. Harris C, Aguirre C, Kolli S, Das K, Izquierdo A, Soltani A. Unique features of stimulus-based probabilistic reversal learning.. Behavioral neuroscience, 2021.
12. Sosa JLR, Buonomano D, Izquierdo A. The orbitofrontal cortex in temporal cognition.. Behavioral neuroscience, 2021.
13. Izquierdo A. Touchscreen response technology and the power of stimulus-based approaches in freely behaving animals.. Genes, brain, and behavior, 2021.
14. Aguirre CG, Stolyarova A, Das K, Kolli S, Marty V, Ray L, Spigelman I, Izquierdo A. Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal.. PloS one, 2020.
15. Hart EE, Blair GJ, O'Dell TJ, Blair HT, Izquierdo A. Chemogenetic Modulation and Single-Photon Calcium Imaging in Anterior Cingulate Cortex Reveal a Mechanism for Effort-Based Decisions.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020.
16. Soltani A, Izquierdo A. Adaptive learning under expected and unexpected uncertainty.. Nature reviews. Neuroscience, 2019.
17. Hart EE, Izquierdo A. Quantity versus quality: Convergent findings in effort-based choice tasks.. Behavioural processes, 2019.
18. Izquierdo A, Aguirre C, Hart EE, Stolyarova A. Rodent Models of Adaptive Value Learning and Decision-Making.. Methods in molecular biology (Clifton, N.J.), 2019.
19. Hart EE, Gerson JO, Izquierdo A. Persistent effect of withdrawal from intravenous methamphetamine self-administration on brain activation and behavioral economic indices involving an effort cost.. Neuropharmacology, 2018.
20. Izquierdo A. Functional Heterogeneity within Rat Orbitofrontal Cortex in Reward Learning and Decision Making.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017.
21. Stolyarova A, Izquierdo A. Complementary contributions of basolateral amygdala and orbitofrontal cortex to value learning under uncertainty.. eLife, 2017.
22. Hart EE, Gerson JO, Zoken Y, Garcia M, Izquierdo A. Anterior cingulate cortex supports effort allocation towards a qualitatively preferred option.. The European journal of neuroscience, 2017.
23. Thompson AB, Gerson J, Stolyarova A, Bugarin A, Hart EE, Jentsch JD, Izquierdo A. Steep effort discounting of a preferred reward over a freely-available option in prolonged methamphetamine withdrawal in male rats.. Psychopharmacology, 2017.
24. Hart EE, Izquierdo A. Basolateral amygdala supports the maintenance of value and effortful choice of a preferred option.. The European journal of neuroscience, 2017.
25. Hart EE, Stolyarova A, Conoscenti MA, Minor TR, Izquierdo A. Rigid patterns of effortful choice behavior after acute stress in rats.. Stress (Amsterdam, Netherlands), 2016.
26. Izquierdo A, Pozos H, Torre Ade L, DeShields S, Cevallos J, Rodriguez J, Stolyarova A. Sex differences, learning flexibility, and striatal dopamine D1 and D2 following adolescent drug exposure in rats.. Behavioural brain research, 2016.
27. Izquierdo A, Brigman JL, Radke AK, Rudebeck PH, Holmes A. The neural basis of reversal learning: An updated perspective.. Neuroscience, 2016.
28. Izquierdo A, Silva AJ. Hijacking translation in addiction.. eLife, 2016.
29. Wassum KM, Izquierdo A. The basolateral amygdala in reward learning and addiction.. Neuroscience and biobehavioral reviews, 2015.
30. Thompson AB, Stolyarova A, Ying Z, Zhuang Y, Gómez-Pinilla F, Izquierdo A. Methamphetamine blocks exercise effects on Bdnf and Drd2 gene expression in frontal cortex and striatum.. Neuropharmacology, 2015.
31. Ochoa JG, Stolyarova A, Kaur A, Hart EE, Bugarin A, Izquierdo A. Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning.. Frontiers in neuroscience, 2015.
32. Stolyarova A, Izquierdo A. Distinct patterns of outcome valuation and amygdala-prefrontal cortex synaptic remodeling in adolescence and adulthood.. Frontiers in behavioral neuroscience, 2015.
33. Stolyarova A, Thompson AB, Barrientos RM, Izquierdo A. Reductions in frontocortical cytokine levels are associated with long-lasting alterations in reward valuation after methamphetamine.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015.
34. Stolyarova A, O'Dell SJ, Marshall JF, Izquierdo A. Positive and negative feedback learning and associated dopamine and serotonin transporter binding after methamphetamine.. Behavioural brain research, 2014.
35. Ye T, Pozos H, Phillips TJ, Izquierdo A. Long-term effects of exposure to methamphetamine in adolescent rats.. Drug and alcohol dependence, 2014.
36. Izquierdo A, Darling C, Manos N, Pozos H, Kim C, Ostrander S, Cazares V, Stepp H, Rudebeck PH. Basolateral amygdala lesions facilitate reward choices after negative feedback in rats.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013.
37. Kosheleff AR, Rodriguez D, O'Dell SJ, Marshall JF, Izquierdo A. Comparison of single-dose and extended methamphetamine administration on reversal learning in rats.. Psychopharmacology, 2012.
38. Izquierdo A, Carlos K, Ostrander S, Rodriguez D, McCall-Craddolph A, Yagnik G, Zhou F. Impaired reward learning and intact motivation after serotonin depletion in rats.. Behavioural brain research, 2012.
39. Izquierdo A, Belcher AM. Rodent models of adaptive decision making.. Methods in molecular biology (Clifton, N.J.), 2012.
40. Izquierdo A, Jentsch JD. Reversal learning as a measure of impulsive and compulsive behavior in addictions.. Psychopharmacology, 2011.
41. Barkus C, Feyder M, Graybeal C, Wright T, Wiedholz L, Izquierdo A, Kiselycznyk C, Schmitt W, Sanderson DJ, Rawlins JN, Saksida LM, Bussey TJ, Sprengel R, Bannerman D, Holmes A. Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?. Neuropharmacology, 2011.
42. Kosheleff AR, Grimes M, O'Dell SJ, Marshall JF, Izquierdo A. Work aversion and associated changes in dopamine and serotonin transporter after methamphetamine exposure in rats.. Psychopharmacology, 2011.
43. Ostrander S, Cazares VA, Kim C, Cheung S, Gonzalez I, Izquierdo A. Orbitofrontal cortex and basolateral amygdala lesions result in suboptimal and dissociable reward choices on cue-guided effort in rats.. Behavioral neuroscience, 2011.
44. Izquierdo A, Murray EA. Functional interaction of medial mediodorsal thalamic nucleus but not nucleus accumbens with amygdala and orbital prefrontal cortex is essential for adaptive response selection after reinforcer devaluation.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010.
45. Izquierdo A, Belcher AM, Scott L, Cazares VA, Chen J, O'Dell SJ, Malvaez M, Wu T, Marshall JF. Reversal-specific learning impairments after a binge regimen of methamphetamine in rats: possible involvement of striatal dopamine.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010.
46. Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, Bussey TJ, Fox S, Deneris E, Murphy DL, Holmes A. Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice.. Cerebral cortex (New York, N.Y. : 1991), 2009.
47. Chudasama Y, Izquierdo A, Murray EA. Distinct contributions of the amygdala and hippocampus to fear expression.. The European journal of neuroscience, 2009.
48. Murray EA, Izquierdo A. Orbitofrontal cortex and amygdala contributions to affect and action in primates.. Annals of the New York Academy of Sciences, 2007.
49. Izquierdo A, Newman TK, Higley JD, Murray EA. Genetic modulation of cognitive flexibility and socioemotional behavior in rhesus monkeys.. Proceedings of the National Academy of Sciences of the United States of America, 2007.
50. Izquierdo A, Murray EA. Selective bilateral amygdala lesions in rhesus monkeys fail to disrupt object reversal learning.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007.
51. Izquierdo A, Wellman CL, Holmes A. Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006.
52. Izquierdo A, Wiedholz LM, Millstein RA, Yang RJ, Bussey TJ, Saksida LM, Holmes A. Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice.. Behavioural brain research, 2006.
53. Izquierdo A, Murray EA. Opposing effects of amygdala and orbital prefrontal cortex lesions on the extinction of instrumental responding in macaque monkeys.. The European journal of neuroscience, 2005.
54. Izquierdo A, Suda RK, Murray EA. Comparison of the effects of bilateral orbital prefrontal cortex lesions and amygdala lesions on emotional responses in rhesus monkeys.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005.
55. Izquierdo A, Suda RK, Murray EA. Bilateral orbital prefrontal cortex lesions in rhesus monkeys disrupt choices guided by both reward value and reward contingency.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004.
56. Izquierdo A, Murray EA. Combined unilateral lesions of the amygdala and orbital prefrontal cortex impair affective processing in rhesus monkeys.. Journal of neurophysiology, 2004.