Hsian-Rong Tseng

Professor, Molecular and Medical Pharmacology, University of California Los Angeles

UC Profile
UCLA Liquid Biopsy Lab

I am currently a Professor in the Department of Molecular & Medical Pharmacology in David Geffen School of Medicine at UCLA. I also hold memberships in the California NanoSystems Institute, Crump Institute for Molecular Imaging, and Jonsson Comprehensive Cancer Center on the UCLA campus. I have over 31 years of experience in organic chemistry, covering synthetic methodology, organometallic, supramolecular and radiochemistry, as well as 21 years of experience in micro- and nanofabrication for applications in electronic and microfluidic devices. To translate our liquid biopsy-based diagnostic technologies into the clinical setting, I established an extensive collaboration network with oncology programs at UCLA and Cedars Sinai Medical Center, and other medical institutions in the US. To facilitate the commercial transition of our NanoVelcro Assays, I founded CytoLumina Technologies Corp., a biotechnology company that has licensed intellectual properties associated with NanoVelcro Assays from UCLA. In October 2019, NanoVelcro Assay was recognized as one of the Success Stories by NCI Innovative Molecular Analysis Technologies (IMAT) program. I co-direct UCLA Liquid Biopsy Laboratory, in which our research team has been working to develop in vitro diagnostics (IVD) technologies for applications in the field of oncology. With continuous support from NIH via R21, R33, R01, P01, U01, U54, and SBIR funding mechanisms, we have built a series of nanotechnology- and microfluidics-enabled IVD technologies that are capable of processing liquid biopsy samples, i.e., extracellular vesicles (EVs) and circulating tumor cells (CTCs). More specifically, our nanomaterials-embedded diagnostic platforms, including NanoVelcro CTC Chips, NanoVilli EV Chips, and Click Chips, introduce powerful non-invasive diagnostic solutions for detection, isolation, and characterization of CTCs and tumor-derived EVs in peripheral blood. Over the past decade, our research endeavors have led to multiple generations of technologies, which have been used to explore the full potential of CTCs and EVs as cancer biomarkers for a variety of clinical applications, e.g., prognostic prediction, disease detection/staging, and treatment monitoring.

Interests

Liquid Biopsy, Non-viral Vectors, In Vitro Diagnostics

Education and Training

University of California, Los AngelesPostdoctoral10/2003Supramolecular and Physical Chemistry
National Taiwan UniversityPhD06/1998Organic Chemistry
Tunghai UniversityBS06/1993Chemistry

Publications

  1. Flowers AE, Gonzalez TL, Wang Y, Santiskulvong C, Clark EL, Novoa A, Jefferies CA, Lawrenson K, Chan JL, Joshi NV, Zhu Y, Tseng HR, Wang ET, Ishimori M, Karumanchi SA, Williams J, Pisarska MD. High-throughput mRNA sequencing of human placenta shows sex differences across gestation.. Placenta, 2024.
  2. Afshar Y, Yin O, Jeong A, Martinez G, Kim J, Ma F, Jang C, Tabatabaei S, You S, Tseng HR, Zhu Y, Krakow D. Placenta accreta spectrum disorder at single-cell resolution: a loss of boundary limits in the decidua and endothelium.. American journal of obstetrics and gynecology, 2024.
  3. Gonzalez TL, Wertheimer S, Flowers AE, Wang Y, Santiskulvong C, Clark EL, Jefferies CA, Lawrenson K, Chan JL, Joshi NV, Zhu Y, Tseng HR, Karumanchi SA, Williams J, Pisarska MD. High-throughput mRNA-seq atlas of human placenta shows vast transcriptome remodeling from first to third trimester.. Biology of reproduction, 2024.
  4. Flora K, Ishihara M, Zhang Z, Bowen ES, Wu A, Ayoub T, Huang J, Cano-Ruiz C, Jackson M, Reghu K, Ayoub Y, Zhu Y, Tseng HR, Zhou ZH, Hu J, Wu L. Exosomes from Von Hippel-Lindau-Null Cancer Cells Promote Metastasis in Renal Cell Carcinoma.. International journal of molecular sciences, 2023.
  5. Gonzalez TL, Wertheimer S, Flowers AE, Wang Y, Santiskulvong C, Clark EL, Jefferies CA, Lawrenson K, Chan JL, Joshi NV, Zhu Y, Tseng HR, Karumanchi SA, Williams J, Pisarska MD. High-throughput mRNA-seq atlas of human placenta shows vast transcriptome remodeling from first to third trimester.. bioRxiv : the preprint server for biology, 2023.
  6. Xu X, Hou S, Wattanatorn N, Wang F, Yang Q, Zhao C, Yu X, Tseng HR, Jonas SJ, Weiss PS. Retraction of "Precision-Guided Nanospears for Targeted and High-Throughput Intracellular Gene Delivery".. ACS nano, 2023.
  7. Gautam B, Luo CH, Gao HD, Hsiao JC, Tseng HR, Lee HM, Yu HH. Nano-On-Nano: Responsive Nanosubstrate-Mediated Liposome Delivery with High Cellular Uptake Efficiency.. ACS applied bio materials, 2023.
  8. Sun N, Zhang C, Wang J, Yue X, Kim HY, Zhang RY, Liu H, Widjaja J, Tang H, Zhang TX, Ye J, Qian A, Liu C, Wu A, Wang K, Johanis M, Yang P, Liu H, Meng M, Liang L, Pei R, Chai-Ho W, Zhu Y, Tseng HR. Hierarchical integration of DNA nanostructures and NanoGold onto a microchip facilitates covalent chemistry-mediated purification of circulating tumor cells in head and neck squamous cell carcinoma.. Nano today, 2023.
  9. Sun N, Zhang C, Lee YT, Tran BV, Wang J, Kim H, Lee J, Zhang RY, Wang JJ, Hu J, Zhang Z, Alsudaney MS, Hou KC, Tang H, Zhang TX, Liang IY, Zhou Z, Chen M, Yeh AH, Li W, Zhou XJ, Chang HR, Han SB, Sadeghi S, Finn RS, Saab S, Busuttil RW, Noureddin M, Ayoub WS, Kuo A, Sundaram V, Al-Ghaieb B, Palomique J, Kosari K, Kim IK, Todo T, Nissen NN, Tomasi ML, You S, Posadas EM, Wu JX, Wadehra M, Sim MS, Li Y, Wang HL, French SW, Lu SC, Wu L, Pei R, Liang L, Yang JD, Agopian VG, Tseng HR, Zhu Y. HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma.. Hepatology (Baltimore, Md.), 2023.
  10. Lee YT, Zhu Y, Yang JD, Agopian VG, Tseng HR. Reply.. Hepatology (Baltimore, Md.), 2023.
  11. Wang JJ, Sun N, Lee YT, Kim M, Vagner T, Rohena-Rivera K, Wang Z, Chen Z, Zhang RY, Lee J, Zhang C, Tang H, Widjaja J, Zhang TX, Qi D, Teng PC, Jan YJ, Hou KC, Hamann C, Sandler HM, Daskivich TJ, Luthringer DJ, Bhowmick NA, Pei R, You S, Di Vizio D, Tseng HR, Chen JF, Zhu Y, Posadas EM. Prostate cancer extracellular vesicle digital scoring assay - a rapid noninvasive approach for quantification of disease-relevant mRNAs.. Nano today, 2023.
  12. Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer.. Nature communications, 2022.
  13. Teng PC, Agopian VG, Lin TY, You S, Zhu Y, Tseng HR, Yang JD. Circulating tumor cells: A step toward precision medicine in hepatocellular carcinoma.. Journal of gastroenterology and hepatology, 2022.
  14. Flowers AE, Gonzalez TL, Joshi NV, Eisman LE, Clark EL, Buttle RA, Sauro E, DiPentino R, Lin Y, Wu D, Wang Y, Santiskulvong C, Tang J, Lee B, Sun T, Chan JL, Wang ET, Jefferies C, Lawrenson K, Zhu Y, Afshar Y, Tseng HR, Williams J, Pisarska MD. Sex differences in microRNA expression in first and third trimester human placenta†.. Biology of reproduction, 2022.
  15. Agopian VG, Yang JD, Zhu Y, You S, Tseng HR. Early detection of primary liver cancer using plasma cell-free DNA fragmentomics: Do all the pieces come together?. Hepatology (Baltimore, Md.), 2022.
  16. Ahn JC, Lee YT, Agopian VG, Zhu Y, You S, Tseng HR, Yang JD. Hepatocellular carcinoma surveillance: current practice and future directions.. Hepatoma research, 2022.
  17. Sun N, Tran BV, Peng Z, Wang J, Zhang C, Yang P, Zhang TX, Widjaja J, Zhang RY, Xia W, Keir A, She JW, Yu HH, Shyue JJ, Zhu H, Agopian VG, Pei R, Tomlinson JS, Toretsky JA, Jonas SJ, Federman N, Lu S, Tseng HR, Zhu Y. Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations.. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022.
  18. Sun N, Yang Y, Miao H, Redublo P, Liu H, Liu W, Huang YW, Teng PC, Zhang C, Zhang RY, Smalley M, Yang P, Chou SJ, Huai K, Zhang Z, Lee YT, Wang JJ, Wang J, Liang IY, Zhang TX, Zhang D, Liang L, Weiss PS, Posadas EM, Donahue T, Hecht JR, Allen-Auerbach MS, Bergsland EK, Hope TA, Pei R, Zhu Y, Tseng HR, Heaney AP. Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips.. Biosensors & bioelectronics, 2021.
  19. Lee YT, Sun N, Kim M, Wang JJ, Tran BV, Zhang RY, Qi D, Zhang C, Chen PJ, Sadeghi S, Finn RS, Saab S, Han SB, Busuttil RW, Pei R, Zhu Y, Tseng HR, You S, Yang JD, Agopian VG. Circulating Tumor Cell-Based Messenger RNA Scoring System for Prognostication of Hepatocellular Carcinoma: Translating Tissue-Based Messenger RNA Profiling Into a Noninvasive Setting.. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2021.
  20. Lee YT, Wang JJ, Luu M, Noureddin M, Kosari K, Agopian VG, Rich NE, Lu SC, Tseng HR, Nissen NN, Singal AG, Yang JD. The Mortality and Overall Survival Trends of Primary Liver Cancer in the United States.. Journal of the National Cancer Institute, 2021.
  21. Lee YT, Wang JJ, Zhu Y, Agopian VG, Tseng HR, Yang JD. Diagnostic Criteria and LI-RADS for Hepatocellular Carcinoma.. Clinical liver disease, 2021.
  22. Afshar Y, Dong J, Zhao P, Li L, Wang S, Zhang RY, Zhang C, Yin O, Han CS, Einerson BD, Gonzalez TL, Zhang H, Zhou A, Yang Z, Chou SJ, Sun N, Cheng J, Zhu H, Wang J, Zhang TX, Lee YT, Wang JJ, Teng PC, Yang P, Qi D, Zhao M, Sim MS, Zhe R, Goldstein JD, Williams J, Wang X, Zhang Q, Platt LD, Zou C, Pisarska MD, Tseng HR, Zhu Y. Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders.. Nature communications, 2021.
  23. Lee YT, Tran BV, Wang JJ, Liang IY, You S, Zhu Y, Agopian VG, Tseng HR, Yang JD. The Role of Extracellular Vesicles in Disease Progression and Detection of Hepatocellular Carcinoma.. Cancers, 2021.
  24. Lee YT, Wang JJ, Luu M, Tseng HR, Rich NE, Lu SC, Nissen NN, Noureddin M, Singal AG, Yang JD. State-Level HCC Incidence and Association With Obesity and Physical Activity in the United States.. Hepatology (Baltimore, Md.), 2021.
  25. Ban Q, Yang P, Chou SJ, Qiao L, Xia H, Xue J, Wang F, Xu X, Sun N, Zhang RY, Zhang C, Lee A, Liu W, Lin TY, Ko YL, Antovski P, Zhang X, Chiou SH, Lee CF, Hui W, Liu D, Jonas SJ, Weiss PS, Tseng HR. Supramolecular Nanosubstrate-Mediated Delivery for CRISPR/Cas9 Gene Disruption and Deletion.. Small (Weinheim an der Bergstrasse, Germany), 2021.
  26. Gonzalez TL, Eisman LE, Joshi NV, Flowers AE, Wu D, Wang Y, Santiskulvong C, Tang J, Buttle RA, Sauro E, Clark EL, DiPentino R, Jefferies CA, Chan JL, Lin Y, Zhu Y, Afshar Y, Tseng HR, Taylor K, Williams J, Pisarska MD. High-throughput miRNA sequencing of the human placenta: expression throughout gestation.. Epigenomics, 2021.
  27. Sun N, Lee YT, Kim M, Wang JJ, Zhang C, Teng PC, Qi D, Zhang RY, Tran BV, Lee YT, Ye J, Palomique J, Nissen NN, Han SB, Sadeghi S, Finn RS, Saab S, Busuttil RW, Posadas EM, Liang L, Pei R, Yang JD, You S, Agopian VG, Tseng HR, Zhu Y. Covalent Chemistry-Mediated Multimarker Purification of Circulating Tumor Cells Enables Noninvasive Detection of Molecular Signatures of Hepatocellular Carcinoma.. Advanced materials technologies, 2021.
  28. Ahn JC, Teng PC, Chen PJ, Posadas E, Tseng HR, Lu SC, Yang JD. Detection of Circulating Tumor Cells and Their Implications as a Biomarker for Diagnosis, Prognostication, and Therapeutic Monitoring in Hepatocellular Carcinoma.. Hepatology (Baltimore, Md.), 2021.
  29. Sun T, Gonzalez TL, Deng N, DiPentino R, Clark EL, Lee B, Tang J, Wang Y, Stripp BR, Yao C, Tseng HR, Karumanchi SA, Koeppel AF, Turner SD, Farber CR, Rich SS, Wang ET, Williams J, Pisarska MD. Sexually Dimorphic Crosstalk at the Maternal-Fetal Interface.. The Journal of clinical endocrinology and metabolism, 2020.
  30. Yang P, Chou SJ, Li J, Hui W, Liu W, Sun N, Zhang RY, Zhu Y, Tsai ML, Lai HI, Smalley M, Zhang X, Chen J, Romero Z, Liu D, Ke Z, Zou C, Lee CF, Jonas SJ, Ban Q, Weiss PS, Kohn DB, Chen K, Chiou SH, Tseng HR. Supramolecular nanosubstrate-mediated delivery system enables CRISPR-Cas9 knockin of hemoglobin beta gene for hemoglobinopathies.. Science advances, 2020.
  31. Dong J, Zhang RY, Sun N, Hu J, Smalley MD, Zhou A, Yue H, Rothermich W, Chen M, Chen J, Ye J, Teng PC, Qi D, Toretsky JA, Tomlinson JS, Li M, Weiss PS, Jonas SJ, Federman N, Wu L, Zhao M, Tseng HR, Zhu Y. Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.. Advanced functional materials, 2020.
  32. Sun N, Lee YT, Zhang RY, Kao R, Teng PC, Yang Y, Yang P, Wang JJ, Smalley M, Chen PJ, Kim M, Chou SJ, Bao L, Wang J, Zhang X, Qi D, Palomique J, Nissen N, Han SB, Sadeghi S, Finn RS, Saab S, Busuttil RW, Markovic D, Elashoff D, Yu HH, Li H, Heaney AP, Posadas E, You S, Yang JD, Pei R, Agopian VG, Tseng HR, Zhu Y. Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring.. Nature communications, 2020.
  33. Winograd P, Hou S, Court CM, Lee YT, Chen PJ, Zhu Y, Sadeghi S, Finn RS, Teng PC, Wang JJ, Zhang Z, Liu H, Busuttil RW, Tomlinson JS, Tseng HR, Agopian VG. Hepatocellular Carcinoma-Circulating Tumor Cells Expressing PD-L1 Are Prognostic and Potentially Associated With Response to Checkpoint Inhibitors.. Hepatology communications, 2020.
  34. Wang J, Sun N, Lee YT, Ni Y, Koochekpour R, Zhu Y, Tseng HR, Wang S, Jiang L, Zhu H. A circulating tumor cell-based digital assay for the detection of EGFR T790M mutation in advanced non-small cell lung cancer.. Journal of materials chemistry. B, 2020.
  35. Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, Tseng HR, Tomlinson JS, Graeber TG, Agopian VG. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells.. NPJ precision oncology, 2020.
  36. Chou SJ, Yang P, Ban Q, Yang YP, Wang ML, Chien CS, Chen SJ, Sun N, Zhu Y, Liu H, Hui W, Lin TC, Wang F, Zhang RY, Nguyen VQ, Liu W, Chen M, Jonas SJ, Weiss PS, Tseng HR, Chiou SH. Dual Supramolecular Nanoparticle Vectors Enable CRISPR/Cas9-Mediated Knockin of Retinoschisin 1 Gene-A Potential Nonviral Therapeutic Solution for X-Linked Juvenile Retinoschisis.. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020.
  37. Febbo PG, Martin AM, Scher HI, Barrett JC, Beaver JA, Beresford PJ, Blumenthal GM, Bramlett K, Compton C, Dittamore R, Eberhard DA, Edelstein D, Godsey J, Gruen A, Hanlon SE, Hicks J, Hovelson D, Hullings M, Johann D, Johnson J, Kolatkar A, Kuhn P, Levine R, Martini JF, Miller DP, Moore C, Moy B, Pathak A, Philip R, Reese D, Royalty W, Ryder M, Sakul H, Salvatore LM, Schade A, Silvestro A, Simmons JK, Simons J, Singh Bhan S, Smalley MD, Somiari SB, Talasaz A, Tewari M, Tseng HR, Vinson J, Wells W, Welsh A, Grossman RL, Lee JSH, Leiman LC. Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases.. Clinical pharmacology and therapeutics, 2020.
  38. Dong J, Chen JF, Smalley M, Zhao M, Ke Z, Zhu Y, Tseng HR. Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications.. Advanced materials (Deerfield Beach, Fla.), 2019.
  39. Dong J, Jan YJ, Cheng J, Zhang RY, Meng M, Smalley M, Chen PJ, Tang X, Tseng P, Bao L, Huang TY, Zhou D, Liu Y, Chai X, Zhang H, Zhou A, Agopian VG, Posadas EM, Shyue JJ, Jonas SJ, Weiss PS, Li M, Zheng G, Yu HH, Zhao M, Tseng HR, Zhu Y. Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells.. Science advances, 2019.
  40. Jan YJ, Yoon J, Chen JF, Teng PC, Yao N, Cheng S, Lozano A, Chu GCY, Chung H, Lu YT, Chen PJ, Wang JJ, Lee YT, Kim M, Zhu Y, Knudsen BS, Feng FY, Garraway IP, Gao AC, Chung LWK, Freeman MR, You S, Tseng HR, Posadas EM. A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.. Theranostics, 2019.
  41. Dong J, Zhang RY, Sun N, Smalley M, Wu Z, Zhou A, Chou SJ, Jan YJ, Yang P, Bao L, Qi D, Tang X, Tseng P, Hua Y, Xu D, Kao R, Meng M, Zheng X, Liu Y, Vagner T, Chai X, Zhou D, Li M, Chiou SH, Zheng G, Di Vizio D, Agopian VG, Posadas E, Jonas SJ, Ju SP, Weiss PS, Zhao M, Tseng HR, Zhu Y. Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer.. ACS applied materials & interfaces, 2019.
  42. Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR. Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.. Cancer research, 2018.
  43. Court CM, Hou S, Winograd P, Segel NH, Li QW, Zhu Y, Sadeghi S, Finn RS, Ganapathy E, Song M, French SW, Naini BV, Sho S, Kaldas FM, Busuttil RW, Tomlinson JS, Tseng HR, Agopian VG. A novel multimarker assay for the phenotypic profiling of circulating tumor cells in hepatocellular carcinoma.. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2018.
  44. Wang F, Yang P, Choi JS, Antovski P, Zhu Y, Xu X, Kuo TH, Lin LE, Kim DNH, Huang PC, Xu H, Lee CF, Wang C, Hsu CC, Chen K, Weiss PS, Tseng HR. Cross-Linked Fluorescent Supramolecular Nanoparticles for Intradermal Controlled Release of Antifungal Drug-A Therapeutic Approach for Onychomycosis.. ACS nano, 2018.
  45. He W, Zhang H, Wang Y, Zhou Y, Luo Y, Cui Y, Jiang N, Jiang W, Wang H, Xu D, Li S, Wang Z, Chen Y, Sun Y, Zhang Y, Tseng HR, Zou X, Wang L, Ke Z. CTHRC1 induces non-small cell lung cancer (NSCLC) invasion through upregulating MMP-7/MMP-9.. BMC cancer, 2018.
  46. Yao N, Jan YJ, Cheng S, Chen JF, Chung LW, Tseng HR, Posadas EM. Structure and function analysis in circulating tumor cells: using nanotechnology to study nuclear size in prostate cancer.. American journal of clinical and experimental urology, 2018.
  47. Xu X, Hou S, Wattanatorn N, Wang F, Yang Q, Zhao C, Yu X, Tseng HR, Jonas SJ, Weiss PS. Precision-Guided Nanospears for Targeted and High-Throughput Intracellular Gene Delivery.. ACS nano, 2018.
  48. Salem AF, Wang S, Billet S, Chen JF, Udompholkul P, Gambini L, Baggio C, Tseng HR, Posadas EM, Bhowmick NA, Pellecchia M. Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide-Drug Conjugate.. Journal of medicinal chemistry, 2018.
  49. Court CM, Ankeny JS, Sho S, Winograd P, Hou S, Song M, Wainberg ZA, Girgis MD, Graeber TG, Agopian VG, Tseng HR, Tomlinson JS. Circulating Tumor Cells Predict Occult Metastatic Disease and Prognosis in Pancreatic Cancer.. Annals of surgical oncology, 2018.
  50. Jan YJ, Chen JF, Zhu Y, Lu YT, Chen SH, Chung H, Smalley M, Huang YW, Dong J, Chen LC, Yu HH, Tomlinson JS, Hou S, Agopian VG, Posadas EM, Tseng HR. NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells.. Advanced drug delivery reviews, 2018.
  51. Hou S, Chen JF, Song M, Zhu Y, Jan YJ, Chen SH, Weng TH, Ling DA, Chen SF, Ro T, Liang AJ, Lee T, Jin H, Li M, Liu L, Hsiao YS, Chen P, Yu HH, Tsai MS, Pisarska MD, Chen A, Chen LC, Tseng HR. Correction to Imprinted NanoVelcro Microchips for Isolation and Characterization of Circulating Fetal Trophoblasts: Toward Noninvasive Prenatal Diagnostics.. ACS nano, 2017.
  52. Shen MY, Chen JF, Luo CH, Lee S, Li CH, Yang YL, Tsai YH, Ho BC, Bao LR, Lee TJ, Jan YJ, Zhu YZ, Cheng S, Feng FY, Chen P, Hou S, Agopian V, Hsiao YS, Tseng HR, Posadas EM, Yu HH. Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection.. Advanced healthcare materials, 2017.
  53. Hou S, Chen JF, Song M, Zhu Y, Jan YJ, Chen SH, Weng TH, Ling DA, Chen SF, Ro T, Liang AJ, Lee T, Jin H, Li M, Liu L, Hsiao YS, Chen P, Yu HH, Tsai MS, Pisarska MD, Chen A, Chen LC, Tseng HR. Imprinted NanoVelcro Microchips for Isolation and Characterization of Circulating Fetal Trophoblasts: Toward Noninvasive Prenatal Diagnostics.. ACS nano, 2017.
  54. Sho S, Court CM, Winograd P, Lee S, Hou S, Graeber TG, Tseng HR, Tomlinson JS. Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications.. BMC cancer, 2017.
  55. Sho S, Court CM, Kim S, Braxton DR, Hou S, Muthusamy VR, Watson RR, Sedarat A, Tseng HR, Tomlinson JS. Digital PCR Improves Mutation Analysis in Pancreas Fine Needle Aspiration Biopsy Specimens.. PloS one, 2017.
  56. Chen JF, Lu YT, Cheng S, Tseng HR, Figlin RA, Posadas EM. Circulating tumor cells in prostate cancer: beyond enumeration.. Clinical advances in hematology & oncology : H&O, 2017.
  57. Choi JS, Zhu Y, Li H, Peyda P, Nguyen TT, Shen MY, Yang YM, Zhu J, Liu M, Lee MM, Sun SS, Yang Y, Yu HH, Chen K, Chuang GS, Tseng HR. Cross-Linked Fluorescent Supramolecular Nanoparticles as Finite Tattoo Pigments with Controllable Intradermal Retention Times.. ACS nano, 2016.
  58. Cheng S, Chen JF, Lu YT, Chung LWK, Tseng HR, Posadas EM. Applications of circulating tumor cells for prostate cancer.. Asian journal of urology, 2016.
  59. Liu S, Tian Z, Zhang L, Hou S, Hu S, Wu J, Jing Y, Sun H, Yu F, Zhao L, Wang R, Tseng HR, Zhau HE, Chung LW, Wu K, Wang H, Wu JB, Nie Y, Shao C. Combined cell surface carbonic anhydrase 9 and CD147 antigens enable high-efficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients.. Oncotarget, 2016.
  60. Wang R, Chu GCY, Mrdenovic S, Annamalai AA, Hendifar AE, Nissen NN, Tomlinson JS, Lewis M, Palanisamy N, Tseng HR, Posadas EM, Freeman MR, Pandol SJ, Zhau HE, Chung LWK. Cultured circulating tumor cells and their derived xenografts for personalized oncology.. Asian journal of urology, 2016.
  61. Nair BG, Hagiwara K, Ueda M, Yu HH, Tseng HR, Ito Y. High Density of Aligned Nanowire Treated with Polydopamine for Efficient Gene Silencing by siRNA According to Cell Membrane Perturbation.. ACS applied materials & interfaces, 2016.
  62. Court CM, Ankeny JS, Sho S, Hou S, Li Q, Hsieh C, Song M, Liao X, Rochefort MM, Wainberg ZA, Graeber TG, Tseng HR, Tomlinson JS. Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer.. The Journal of molecular diagnostics : JMD, 2016.
  63. Chen JF, Zhu Y, Lu YT, Hodara E, Hou S, Agopian VG, Tomlinson JS, Posadas EM, Tseng HR. Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells.. Theranostics, 2016.
  64. Zhao L, Tang C, Xu L, Zhang Z, Li X, Hu H, Cheng S, Zhou W, Huang M, Fong A, Liu B, Tseng HR, Gao H, Liu Y, Fang X. Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail.. Small (Weinheim an der Bergstrasse, Germany), 2016.
  65. Hou S, Choi JS, Garcia MA, Xing Y, Chen KJ, Chen YM, Jiang ZK, Ro T, Wu L, Stout DB, Tomlinson JS, Wang H, Chen K, Tseng HR, Lin WY. Pretargeted Positron Emission Tomography Imaging That Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry.. ACS nano, 2016.
  66. Jiang R, Lu YT, Ho H, Li B, Chen JF, Lin M, Li F, Wu K, Wu H, Lichterman J, Wan H, Lu CL, OuYang W, Ni M, Wang L, Li G, Lee T, Zhang X, Yang J, Rettig M, Chung LW, Yang H, Li KC, Hou Y, Tseng HR, Hou S, Xu X, Wang J, Posadas EM. A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer.. Oncotarget, 2015.
  67. Liu Y, Du J, Choi JS, Chen KJ, Hou S, Yan M, Lin WY, Chen KS, Ro T, Lipshutz GS, Wu L, Shi L, Lu Y, Tseng HR, Wang H. A High-Throughput Platform for Formulating and Screening Multifunctional Nanoparticles Capable of Simultaneous Delivery of Genes and Transcription Factors.. Angewandte Chemie (International ed. in English), 2015.
  68. Rim YS, Bae SH, Chen H, Yang JL, Kim J, Andrews AM, Weiss PS, Yang Y, Tseng HR. Printable Ultrathin Metal Oxide Semiconductor-Based Conformal Biosensors.. ACS nano, 2015.
  69. Court CM, Ankeny JS, Hou S, Tseng HR, Tomlinson JS. Improving pancreatic cancer diagnosis using circulating tumor cells: prospects for staging and single-cell analysis.. Expert review of molecular diagnostics, 2015.
  70. Chen JF, Ho H, Lichterman J, Lu YT, Zhang Y, Garcia MA, Chen SF, Liang AJ, Hodara E, Zhau HE, Hou S, Ahmed RS, Luthringer DJ, Huang J, Li KC, Chung LW, Ke Z, Tseng HR, Posadas EM. Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases.. Cancer, 2015.
  71. Hou S, Choi JS, Chen KJ, Zhang Y, Peng J, Garcia MA, Yu JH, Thakore-Shah K, Ro T, Chen JF, Peyda P, Fan G, Pyle AD, Wang H, Tseng HR. Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.. Small (Weinheim an der Bergstrasse, Germany), 2015.
  72. Ke Z, Lin M, Chen JF, Choi JS, Zhang Y, Fong A, Liang AJ, Chen SF, Li Q, Fang W, Zhang P, Garcia MA, Lee T, Song M, Lin HA, Zhao H, Luo SC, Hou S, Yu HH, Tseng HR. Programming thermoresponsiveness of NanoVelcro substrates enables effective purification of circulating tumor cells in lung cancer patients.. ACS nano, 2014.
  73. Lin M, Chen JF, Lu YT, Zhang Y, Song J, Hou S, Ke Z, Tseng HR. Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells.. Accounts of chemical research, 2014.
  74. Peng J, Garcia MA, Choi JS, Zhao L, Chen KJ, Bernstein JR, Peyda P, Hsiao YS, Liu KW, Lin WY, Pyle AD, Wang H, Hou S, Tseng HR. Molecular recognition enables nanosubstrate-mediated delivery of gene-encapsulated nanoparticles with high efficiency.. ACS nano, 2014.
  75. Hsiao YS, Luo SC, Hou S, Zhu B, Sekine J, Kuo CW, Chueh DY, Yu HH, Tseng HR, Chen P. 3D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control.. Small (Weinheim an der Bergstrasse, Germany), 2014.
  76. Lu YT, Zhao L, Shen Q, Garcia MA, Wu D, Hou S, Song M, Xu X, Ouyang WH, Ouyang WW, Lichterman J, Luo Z, Xuan X, Huang J, Chung LW, Rettig M, Tseng HR, Shao C, Posadas EM. NanoVelcro Chip for CTC enumeration in prostate cancer patients.. Methods (San Diego, Calif.), 2013.
  77. Zhao L, Lu YT, Li F, Wu K, Hou S, Yu J, Shen Q, Wu D, Song M, OuYang WH, Luo Z, Lee T, Fang X, Shao C, Xu X, Garcia MA, Chung LW, Rettig M, Tseng HR, Posadas EM. High-purity prostate circulating tumor cell isolation by a polymer nanofiber-embedded microchip for whole exome sequencing.. Advanced materials (Deerfield Beach, Fla.), 2013.
  78. Lee JH, Chen KJ, Noh SH, Garcia MA, Wang H, Lin WY, Jeong H, Kong BJ, Stout DB, Cheon J, Tseng HR. On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles.. Angewandte Chemie (International ed. in English), 2013.
  79. Shen Q, Xu L, Zhao L, Wu D, Fan Y, Zhou Y, Ouyang WH, Xu X, Zhang Z, Song M, Lee T, Garcia MA, Xiong B, Hou S, Tseng HR, Fang X. Specific capture and release of circulating tumor cells using aptamer-modified nanosubstrates.. Advanced materials (Deerfield Beach, Fla.), 2013.
  80. Hou S, Zhao L, Shen Q, Yu J, Ng C, Kong X, Wu D, Song M, Shi X, Xu X, OuYang WH, He R, Zhao XZ, Lee T, Brunicardi FC, Garcia MA, Ribas A, Lo RS, Tseng HR. Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells.. Angewandte Chemie (International ed. in English), 2013.
  81. Hou S, Zhao H, Zhao L, Shen Q, Wei KS, Suh DY, Nakao A, Garcia MA, Song M, Lee T, Xiong B, Luo SC, Tseng HR, Yu HH. Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.. Advanced materials (Deerfield Beach, Fla.), 2012.
  82. Chen KJ, Tang L, Garcia MA, Wang H, Lu H, Lin WY, Hou S, Yin Q, Shen CK, Cheng J, Tseng HR. The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles.. Biomaterials, 2011.
  83. Sekine J, Luo SC, Wang S, Zhu B, Tseng HR, Yu HH. Functionalized conducting polymer nanodots for enhanced cell capturing: the synergistic effect of capture agents and nanostructures.. Advanced materials (Deerfield Beach, Fla.), 2011.
  84. Liu K, Lepin EJ, Wang MW, Guo F, Lin WY, Chen YC, Sirk SJ, Olma S, Phelps ME, Zhao XZ, Tseng HR, Michael van Dam R, Wu AM, Shen CK. Microfluidic-based 18F-labeling of biomolecules for immuno-positron emission tomography.. Molecular imaging, 2011.
  85. Vu NT, Yu ZT, Comin-Anduix B, Søndergaard JN, Silverman RW, Chang CY, Ribas A, Tseng HR, Chatziioannou AF. A beta-camera integrated with a microfluidic chip for radioassays based on real-time imaging of glycolysis in small cell populations.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011.
  86. Wang S, Liu K, Liu J, Yu ZT, Xu X, Zhao L, Lee T, Lee EK, Reiss J, Lee YK, Chung LW, Huang J, Rettig M, Seligson D, Duraiswamy KN, Shen CK, Tseng HR. Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers.. Angewandte Chemie (International ed. in English), 2011.
  87. Liu Y, Wang H, Kamei K, Yan M, Chen KJ, Yuan Q, Shi L, Lu Y, Tseng HR. Delivery of intact transcription factor by using self-assembled supramolecular nanoparticles.. Angewandte Chemie (International ed. in English), 2011.
  88. Kamei K, Sun J, Tseng HR, Damoiseaux R. Microfluidic image cytometry.. Methods in molecular biology (Clifton, N.J.), 2011.
  89. Wang S, Owens GE, Tseng HR. Nano "fly paper" technology for the capture of circulating tumor cells.. Methods in molecular biology (Clifton, N.J.), 2011.
  90. Chen KJ, Wolahan SM, Wang H, Hsu CH, Chang HW, Durazo A, Hwang LP, Garcia MA, Jiang ZK, Wu L, Lin YY, Tseng HR. A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity.. Biomaterials, 2010.
  91. Wang H, Liu K, Chen KJ, Lu Y, Wang S, Lin WY, Guo F, Kamei K, Chen YC, Ohashi M, Wang M, Garcia MA, Zhao XZ, Shen CK, Tseng HR. A rapid pathway toward a superb gene delivery system: programming structural and functional diversity into a supramolecular nanoparticle library.. ACS nano, 2010.
  92. Liu K, Wang H, Chen KJ, Guo F, Lin WY, Chen YC, Phung DL, Tseng HR, Shen CK. A digital microfluidic droplet generator produces self-assembled supramolecular nanoparticles for targeted cell imaging.. Nanotechnology, 2010.
  93. Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG. Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples.. Cancer research, 2010.
  94. Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, Liu M, Zhang N, Wang S, Angenieux B, Panosyan E, Samuels ER, Park J, Williams D, Konkankit V, Nathanson D, van Dam RM, Phelps ME, Wu H, Liau LM, Mischel PS, Lazareff JA, Kornblum HI, Yong WH, Graeber TG, Tseng HR. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.. Cancer research, 2010.
  95. Wang S, Chen KJ, Wu TH, Wang H, Lin WY, Ohashi M, Chiou PY, Tseng HR. Photothermal effects of supramolecularly assembled gold nanoparticles for the targeted treatment of cancer cells.. Angewandte Chemie (International ed. in English), 2010.
  96. Liu K, Chen YC, Tseng HR, Shen CK, van Dam RM. Microfluidic device for robust generation of two-component liquid-in-air slugs with individually controlled composition.. Microfluidics and nanofluidics, 2010.
  97. Kamei K, Ohashi M, Gschweng E, Ho Q, Suh J, Tang J, For Yu ZT, Clark AT, Pyle AD, Teitell MA, Lee KB, Witte ON, Tseng HR. Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions.. Lab on a chip, 2010.
  98. Sherman DJ, Kenanova VE, Lepin EJ, McCabe KE, Kamei K, Ohashi M, Wang S, Tseng HR, Wu AM, Behrenbruch CP. A differential cell capture assay for evaluating antibody interactions with cell surface targets.. Analytical biochemistry, 2010.
  99. Wang H, Chen KJ, Wang S, Ohashi M, Kamei K, Sun J, Ha JH, Liu K, Tseng HR. A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery.. Chemical communications (Cambridge, England), 2010.
  100. Jung J, Solanki A, Memoli KA, Kamei K, Kim H, Drahl MA, Williams LJ, Tseng HR, Lee K. Selective inhibition of human brain tumor cells through multifunctional quantum-dot-based siRNA delivery.. Angewandte Chemie (International ed. in English), 2010.
  101. Lin WY, Wang Y, Wang S, Tseng HR. Integrated Microfluidic Reactors.. Nano today, 2009.
  102. Wang Y, Lin WY, Liu K, Lin RJ, Selke M, Kolb HC, Zhang N, Zhao XZ, Phelps ME, Shen CK, Faull KF, Tseng HR. An integrated microfluidic device for large-scale in situ click chemistry screening.. Lab on a chip, 2009.
  103. Yu ZT, Kamei K, Takahashi H, Shu CJ, Wang X, He GW, Silverman R, Radu CG, Witte ON, Lee KB, Tseng HR. Integrated microfluidic devices for combinatorial cell-based assays.. Biomedical microdevices, 2009.
  104. Wang H, Wang S, Su H, Chen KJ, Armijo AL, Lin WY, Wang Y, Sun J, Kamei K, Czernin J, Radu CG, Tseng HR. A supramolecular approach for preparation of size-controlled nanoparticles.. Angewandte Chemie (International ed. in English), 2009.
  105. Wang S, Wang H, Jiao J, Chen KJ, Owens GE, Kamei K, Sun J, Sherman DJ, Behrenbruch CP, Wu H, Tseng HR. Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells.. Angewandte Chemie (International ed. in English), 2009.
  106. Kamei K, Guo S, Yu ZT, Takahashi H, Gschweng E, Suh C, Wang X, Tang J, McLaughlin J, Witte ON, Lee KB, Tseng HR. An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells.. Lab on a chip, 2008.
  107. Cotí KK, Wang Y, Lin WY, Chen CC, Tak For Yu Z, Liu K, Shen CK, Selke M, Yeh A, Lu W, Tseng HR. A dynamic micromixer for arbitrary control of disguised chemical selectivity.. Chemical communications (Cambridge, England), 2008.
  108. Hou S, Wang S, Yu ZT, Zhu NQ, Liu K, Sun J, Lin WY, Shen CK, Fang X, Tseng HR. A hydrodynamically focused stream as a dynamic template for site-specific electrochemical micropatterning of conducting polymers.. Angewandte Chemie (International ed. in English), 2008.
  109. Wang Y, Coti KK, Wang J, Alam MM, Shyue JJ, Lu W, Padture NP, Tseng HR. Individually addressable crystalline conducting polymer nanowires in a microelectrode sensor array.. Nanotechnology, 2007.
  110. Sui G, Lee CC, Kamei K, Li HJ, Wang JY, Wang J, Herschman HR, Tseng HR. A microfluidic platform for sequential ligand labeling and cell binding analysis.. Biomedical microdevices, 2007.
  111. Green JE, Choi JW, Boukai A, Bunimovich Y, Johnston-Halperin E, DeIonno E, Luo Y, Sheriff BA, Xu K, Shin YS, Tseng HR, Stoddart JF, Heath JR. A 160-kilobit molecular electronic memory patterned at 10(11) bits per square centimetre.. Nature, 2007.
  112. Ferrer B, Rogez G, Credi A, Ballardini R, Gandolfi MT, Balzani V, Liu Y, Tseng HR, Stoddart JF. Photoinduced electron flow in a self-assembling supramolecular extension cable.. Proceedings of the National Academy of Sciences of the United States of America, 2006.
  113. Leung KC, Mendes PM, Magonov SN, Northrop BH, Kim S, Patel K, Flood AH, Tseng HR, Stoddart JF. Supramolecular self-assembly of dendronized polymers: reversible control of the polymer architectures through acid-base reactions.. Journal of the American Chemical Society, 2006.
  114. Wang J, Sui G, Mocharla VP, Lin RJ, Phelps ME, Kolb HC, Tseng HR. Integrated microfluidics for parallel screening of an in situ click chemistry library.. Angewandte Chemie (International ed. in English), 2006.
  115. Sui G, Wang J, Lee CC, Lu W, Lee SP, Leyton JV, Wu AM, Tseng HR. Solution-phase surface modification in intact poly(dimethylsiloxane) microfluidic channels.. Analytical chemistry, 2006.
  116. Wang J, Bunimovich YL, Sui G, Savvas S, Wang J, Guo Y, Heath JR, Tseng HR. Electrochemical fabrication of conducting polymer nanowires in an integrated microfluidic system.. Chemical communications (Cambridge, England), 2006.
  117. Brough B, Northrop BH, Schmidt JJ, Tseng HR, Houk KN, Stoddart JF, Ho CM. Evaluation of synthetic linear motor-molecule actuation energetics.. Proceedings of the National Academy of Sciences of the United States of America, 2006.
  118. DeIonno E, Tseng HR, Harvey DD, Stoddart JF, Heath JR. Infrared spectroscopic characterization of [2]rotaxane molecular switch tunnel junction devices.. The journal of physical chemistry. B, 2006.
  119. Mendes PM, Lu W, Tseng HR, Shinder S, Iijima T, Miyaji M, Knobler CM, Stoddart JF. A soliton phenomenon in langmuir monolayers of amphiphilic bistable rotaxanes.. The journal of physical chemistry. B, 2006.
  120. Lee CC, Sui G, Elizarov A, Shu CJ, Shin YS, Dooley AN, Huang J, Daridon A, Wyatt P, Stout D, Kolb HC, Witte ON, Satyamurthy N, Heath JR, Phelps ME, Quake SR, Tseng HR. Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics.. Science (New York, N.Y.), 2005.
  121. Saha S, Johansson E, Flood AH, Tseng HR, Zink JI, Stoddart JF. A photoactive molecular triad as a nanoscale power supply for a supramolecular machine.. Chemistry (Weinheim an der Bergstrasse, Germany), 2005.
  122. Nørgaard K, Laursen BW, Nygaard S, Kjaer K, Tseng HR, Flood AH, Stoddart JF, Bjørnholm T. Structural evidence of mechanical shuttling in condensed monolayers of bistable rotaxane molecules.. Angewandte Chemie (International ed. in English), 2005.
  123. Liu Y, Flood AH, Bonvallet PA, Vignon SA, Northrop BH, Tseng HR, Jeppesen JO, Huang TJ, Brough B, Baller M, Magonov S, Solares SD, Goddard WA, Ho CM, Stoddart JF. Linear artificial molecular muscles.. Journal of the American Chemical Society, 2005.
  124. Nguyen TD, Tseng HR, Celestre PC, Flood AH, Liu Y, Stoddart JF, Zink JI. A reversible molecular valve.. Proceedings of the National Academy of Sciences of the United States of America, 2005.
  125. Alam MM, Wang J, Guo Y, Lee SP, Tseng HR. Electrolyte-gated transistors based on conducting polymer nanowire junction arrays.. The journal of physical chemistry. B, 2005.
  126. Jang SS, Jang YH, Kim YH, Goddard WA, Flood AH, Laursen BW, Tseng HR, Stoddart JF, Jeppesen JO, Choi JW, Steuerman DW, Deionno E, Heath JR. Structures and properties of self-assembled monolayers of bistable [2]rotaxanes on Au (111) surfaces from molecular dynamics simulations validated with experiment.. Journal of the American Chemical Society, 2005.
  127. Saha S, Johansson LE, Flood AH, Tseng HR, Zink JI, Stoddart JF. Powering a supramolecular machine with a photoactive molecular triad.. Small (Weinheim an der Bergstrasse, Germany), 2005.
  128. Marchioni F, Venturi M, Ceroni P, Balzani V, Belohradsky M, Elizarov AM, Tseng HR, Stoddart JF. Complete charge pooling is prevented in viologen-based dendrimers by self-protection.. Chemistry (Weinheim an der Bergstrasse, Germany), 2004.
  129. Iijima T, Vignon SA, Tseng HR, Jarrosson T, Sanders JK, Marchioni F, Venturi M, Apostoli E, Balzani V, Stoddart JF. Controllable donor-acceptor neutral [2]rotaxanes.. Chemistry (Weinheim an der Bergstrasse, Germany), 2004.
  130. Steuerman DW, Tseng HR, Peters AJ, Flood AH, Jeppesen JO, Nielsen KA, Stoddart JF, Heath JR. Molecular-mechanical switch-based solid-state electrochromic devices.. Angewandte Chemie (International ed. in English), 2004.
  131. Flood AH, Peters AJ, Vignon SA, Steuerman DW, Tseng HR, Kang S, Heath JR, Stoddart JF. The role of physical environment on molecular electromechanical switching.. Chemistry (Weinheim an der Bergstrasse, Germany), 2004.
  132. Vignon SA, Jarrosson T, Iijima T, Tseng HR, Sanders JK, Stoddart JF. Switchable neutral bistable rotaxanes.. Journal of the American Chemical Society, 2004.
  133. Lee IC, Frank CW, Yamamoto T, Tseng HR, Flood AH, Stoddart JF, Jeppesen JO. Langmuir and Langmuir-Blodgett films of amphiphilic bistable rotaxanes.. Langmuir : the ACS journal of surfaces and colloids, 2004.
  134. Kang S, Vignon SA, Tseng HR, Stoddart JF. Molecular shuttles based on tetrathiafulvalene units and 1,5-dioxynaphthalene ring systems.. Chemistry (Weinheim an der Bergstrasse, Germany), 2004.
  135. Vignon SA, Wong J, Tseng HR, Stoddart JF. Helical chirality in donor-acceptor catenanes.. Organic letters, 2004.
  136. Hernandez R, Tseng HR, Wong JW, Stoddart JF, Zink JI. An operational supramolecular nanovalve.. Journal of the American Chemical Society, 2004.
  137. Tseng HR, Wu D, Fang NX, Zhang X, Stoddart JF. The metastability of an electrochemically controlled nanoscale machine on gold surfaces.. Chemphyschem : a European journal of chemical physics and physical chemistry, 2004.
  138. Marchioni F, Venturi M, Credi A, Balzani V, Belohradsky M, Elizarov AM, Tseng HR, Stoddart JF. Polyvalent scaffolds. Counting the number of seats available for eosin guest molecules in viologen-based host dendrimers.. Journal of the American Chemical Society, 2004.
  139. Tseng HR, Vignon SA, Celestre PC, Perkins J, Jeppesen JO, Di Fabio A, Ballardini R, Gandolfi MT, Venturi M, Balzani V, Stoddart JF. Redox-controllable amphiphilic [2]rotaxanes.. Chemistry (Weinheim an der Bergstrasse, Germany), 2004.
  140. Diehl MR, Steuerman DW, Tseng HR, Vignon SA, Star A, Celestre PC, Stoddart JF, Heath JR. Single-walled carbon nanotube based molecular switch tunnel junctions.. Chemphyschem : a European journal of chemical physics and physical chemistry, 2003.
  141. Yu H, Luo Y, Beverly K, Stoddart JF, Tseng HR, Heath JR. The molecule-electrode interface in single-molecule transistors.. Angewandte Chemie (International ed. in English), 2003.
  142. Tseng HR, Vignon SA, Stoddart JF. Toward chemically controlled nanoscale molecular machinery.. Angewandte Chemie (International ed. in English), 2003.
  143. Tseng HR, Vignon SA, Celestre PC, Stoddart JF, White AJ, Williams DJ. Dynamic chirality: keen selection in the face of stereochemical diversity in mechanically bonded compounds.. Chemistry (Weinheim an der Bergstrasse, Germany), 2003.
  144. Luo Y, Collier PC, Jeppesen JO, Nielsen KA, Delonno E, Ho G, Perkins J, Tseng HR, Yamamoto T, Stoddart JF, Heath JR. Two-dimensional molecular electronics circuits.. Chemphyschem : a European journal of chemical physics and physical chemistry, 2002.
  145. Stoddart JF, Tseng HR. Chemical synthesis gets a fillip from molecular recognition and self-assembly processes.. Proceedings of the National Academy of Sciences of the United States of America, 2002.