Charalabos Pothoulakis

Charalabos Pothoulakis

Professor, Medicine, University of California Los Angeles


675 Charles E. Young Dr. South
MRL 1240, Box 957019
Los Angeles, CA 90095


UCLA Vatche and Tamar Manoukian Division of Digestive Diseases

UCLA Center for Inflammatory Bowel Diseases

Pothoulakis Laboratory


Eli and Edythe Broad Chair, Medicine
Director of Research, UCLA Center for Inflammatory Bowel Diseases
Director, Research Integration
Member, CTSI, I3T Theme, Immunity, Microbes & Molecular Pathogenesis GPB Home Area, Molecular, Cellular & Integrative Physiology GPB Home Area, Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC)


Dr. Pothoulakis’ research program is primarily focused on the role of neuropeptides and hormones in several disease states, including inflammatory bowel disease, Clostridium difficile infection, and irritable bowel syndrome. His recent projects also involve characterization of neuropeptide-microRNA dependent signaling mechanisms that modulate development of colitis and inflammatory bowel disease. In 2005, Dr. Pothoulakis received an honorary degree from Harvard University and he is the recipient of the “Janssen Award in Basic Research in Gastrointestinal Motility” by the American Gastroenterological Association for his discoveries and insights into the function of gastrointestinal neuropeptides. In 2017 he also received the Mentor Award from the Cellular and Molecular Gastroenterology Section of the American Gastroenterological Association. Dr. Pothoulakis’ research projects have been supported by grants from the National Institutes of Health, the Broad Foundation, The Martin Blinder Foundation for Crohn’s Disease, and the Knapp Foundation.