Danielle L Schmitt

Assistant Professor, Chemistry and Biochemistry, University of California Los Angeles

UC Profile

Publications

  1. Jhawar A, Parks K, Schmitt DL. Illuminating compartmentalized AMPK signaling in single cells.. The Biochemical journal, 2026.
  2. Lee REC, Yeung J, Mumford T, Bugaj L, Daniels MJ, Stanley J, Pourmand N, Vineall KG, Schmitt DL, Rahman SMT, Sung MH. Noninvasive methods to monitor dynamic single-cell events.. Trends in cell biology, 2026.
  3. Vineall KG, Andrikopoulos A, Sun MJ, Yan A, Hartanto ER, Schmitt DL. Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity Reporter.. ACS sensors, 2026.
  4. Scully JM, Sun MJ, Das S, Arias NJ, Kapelczak ED, Robinson TD, Vineall KG, Dean TS, TeSlaa T, Divakaruni AS, Schmitt DL. Illuminating spatial dynamics of glutamine metabolism with a sensitive genetically encoded biosensor.. bioRxiv : the preprint server for biology, 2026.
  5. Parks K, Jhawar A, Andrikopoulos A, Winters DM, Dean TS, Kapelczak ED, TeSlaa T, Bouhaddou M, Schmitt DL. Spatial regulation of AMPK activity under oxidative stress requires LKB1.. bioRxiv : the preprint server for biology, 2025.
  6. Brennan PJ, Saunders RE, Spanou M, Singleton SE, Serafini M, Sun L, Heger GP, Konopacka A, Beveridge RD, Taylor CC, DePaola P, Gordon L, Bunally SB, Saudemont A, Benowitz AB, Martinez-Fleites C, Schmitt DL, Damoiseaux R, Queisser MA, An H, Deane CM, Hann MM, Brayshaw LL, Conway SJ. Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.. ACS chemical biology, 2025.
  7. Vineall KG, Andrikopoulos A, Sun MJ, Yan A, Hartanto ER, Schmitt DL. Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity Reporter.. bioRxiv : the preprint server for biology, 2025.
  8. Ranzau BL, Robinson TD, Scully JM, Kapelczak ED, Dean TS, TeSlaa T, Schmitt DL. A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA.. ACS bio & med chem Au, 2024.
  9. Ranzau BL, Robinson TD, Scully JM, Kapelczack ED, Dean TS, TeSlaa T, Schmitt DL. A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA.. bioRxiv : the preprint server for biology, 2024.
  10. Jeon M, Schmitt DL, Kyoung M, An S. Size-Specific Modulation of a Multienzyme Glucosome Assembly during the Cell Cycle.. ACS bio & med chem Au, 2023.
  11. Schmitt DL, Dranchak P, Parajuli P, Blivis D, Voss T, Kohnhorst CL, Kyoung M, Inglese J, An S. High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells.. PloS one, 2023.
  12. Schmitt DL. Imaging Subcellular AMPK Activity Using an Excitation-Ratiometric AMPK Activity Reporter.. Current protocols, 2023.
  13. Liu L, Wang Y, Schmitt DL. LUNAS: A Rapid and Sensitive Nucleic Acid Detection Assay Using Split NanoLuc Luciferase Complementation.. ACS central science, 2023.
  14. Peng Q, Huang Z, Sun K, Liu Y, Yoon CW, Harrison RES, Schmitt DL, Zhu L, Wu Y, Tasan I, Zhao H, Zhang J, Zhong S, Chien S, Wang Y. Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells.. Nature communications, 2022.
  15. Schmitt DL, Mehta S, Zhang J. Study of spatiotemporal regulation of kinase signaling using genetically encodable molecular tools.. Current opinion in chemical biology, 2022.
  16. Schmitt DL, Curtis SD, Lyons AC, Zhang JF, Chen M, He CY, Mehta S, Shaw RJ, Zhang J. Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter.. Nature communications, 2022.
  17. Schmitt DL, Mehta S, Zhang J. Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors.. Current opinion in chemical biology, 2020.
  18. Ohadi D, Schmitt DL, Calabrese B, Halpain S, Zhang J, Rangamani P. Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines.. Biophysical journal, 2019.
  19. Schmitt DL, Sundaram A, Jeon M, Luu BT, An S. Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways.. PloS one, 2018.
  20. Schmitt DL, An S. Spatial Organization of Metabolic Enzyme Complexes in Cells.. Biochemistry, 2017.
  21. Schmitt DL, Cheng YJ, Park J, An S. Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK.. ACS chemical biology, 2016.