Affiliations

Director, Epilepsy Surgery, Pediatric Epilepsy Program
Member, Brain Research Institute, Neuroscience GPB Home Area, Pediatric Neuro-oncology and Neural Tumors Center

Biography

Dr. Mathern graduated from the Case Western Reserve University School of Medicine in 1982. He completed his Rotating Internship at the Cleveland Clinic Foundation in 1983 and his Residencies in Surgery (1985) and Neurosurgery (1986-1991) at UCLA Harbor Medical Center and UCLA School of Medicine, respectively.  Dr. Mathern received his Board Certification in Neurological Surgery in 1996.  He currently practices medicine at the David Geffen UCLA School of Medicine and specializes in Neurological Surgery and Pediatric Neurological Surgery. Dr. Mathern is affiliated with both Santa Monica UCLA Medical Center and Ronald Reagan UCLA Medical Center.

HOSPITAL POSITIONS

• Dr. Alfonsina Q. Davies Endowed Chair in Honor of Paul Crandall, M.D. for Epilepsy Research
• Professor in Residence, David Geffen UCLA School of Medicine, Department of Neurosurgery, Psychiatry and Biobehavioral Sciences, Mattel Children’s Hospital
• Faculty, Intellectual Developmental Disabilities Research Center (IDDRC), David Geffen UCLA School of Medicine
• Faculty, Brain Research Institute, David Geffen UCLA School of Medicine
• Faculty, Interdepartmental PhD Program for Neuroscience, David Geffen UCLA School of Medicine

Professional Associations

• American Association of Neurological Surgeons
• American Association for the Advancement of Science
• American Clinical Neurophysiology Society
• American Epilepsy Society
• University of California, Irvine EpiCenter
• International League Against Epilepsy
• Congress of Neurological Surgeons
• Society for Neuroscience

Publications

A selected list of publications:

• de Bode Stella, Smets Lieselotte, Mathern Gary W, Dubinsky Stanley   Complex syntax in the isolated right hemisphere: Receptive grammatical abilities after cerebral hemispherectomy Epilepsy & behavior : E&B, 2015; 51: 33-39.
• Owens Geoffrey C, Erickson Kate L, Malone Colin C, Pan Calvin, Huynh My N, Chang Julia W, Chirwa Thabiso, Vinters Harry V, Mathern Gary W, Kruse Carol A   Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis Journal of neuroinflammation, 2015; 12: 134.
• Diamond Matthew, Mathern Gary, Nehlig Astrid, Sperling Michael   Interview with Matthew Diamond, 2014 Epilepsia prize winner Epilepsia, 2015; 56(7): 987-8.
• Baca Christine B, Pieters Huibrie C, Iwaki Tomoko J, Mathern Gary W, Vickrey Barbara G   “A journey around the world”: Parent narratives of the journey to pediatric resective epilepsy surgery and beyond Epilepsia, 2015; 56(6): 822-32.
• de Bode Stella, Chanturidze Marine, Mathern Gary W, Dubinsky Stanley   Literacy after cerebral hemispherectomy: Can the isolated right hemisphere read? Epilepsy & behavior : E&B, 2015; 45(4): 248-53.
• D’Gama Alissa M, Geng Ying, Couto Javier A, Martin Beth, Boyle Evan A, LaCoursiere Christopher M, Hossain Amer, Hatem Nicole E, Barry Brenda J, Kwiatkowski David J, Vinters Harry V, Barkovich A James, Shendure Jay, Mathern Gary W, Walsh Christopher A, Poduri Annapurna   Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia Annals of neurology, 2015; 77(4): 720-5.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   Should consciousness describe seizures and what terms should be applied? Epilepsia’s survey results Epilepsia, 2015; 56(3): 340-3.
• Abdijadid Sara, Mathern Gary W, Levine Michael S, Cepeda Carlos   Basic mechanisms of epileptogenesis in pediatric cortical dysplasia CNS neuroscience & therapeutics, 2015; 21(2): 92-103.
• Mathern Gary W, Nehlig Astrid   Global awareness and International Epilepsy Day Epilepsia, 2015; 56(2): 167.
• Cepeda Carlos, Chang Julia W, Owens Geoffrey C, Huynh My N, Chen Jane Y, Tran Conny, Vinters Harry V, Levine Michael S, Mathern Gary W   In Rasmussen encephalitis, hemichannels associated with microglial activation are linked to cortical pyramidal neuron coupling: a possible mechanism for cellular hyperexcitability CNS neuroscience & therapeutics, 2015; 21(2): 152-63.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   Reasons for discrepancy between incidence and prevalence of epilepsy in lower income countries: Epilepsia’s survey results Epilepsia, 2015; 56(2): 163-5.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   Fewer specialists support using medical marijuana and CBD in treating epilepsy patients compared with other medical professionals and patients: result of Epilepsia’s survey Epilepsia, 2015; 56(1): 1-6.
• Jehi Lara, Mathern Gary W   Who’s responsible to refer for epilepsy surgery? We all are! Neurology, 2015; 84(2): 112-3.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   From the editors: Epilepsia’s survey on the necessity of the Wada test and intracranial electrodes for cortical mapping Epilepsia, 2014; 55(12): 1887-9.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   From the editors: Epilepsia’s 2014 Operational Definition of Epilepsy survey Epilepsia, 2014; 55(11): 1683-7.
• Mathern Gary, Nehlig Astrid, Hesdorffer Dale C   SUDEP’s health burden and when to talk about it Epilepsia, 2014; 55(10): 1477-8.
• Mathern Gary W, Nehlig Astrid   From the editors: using consciousness to describe seizures and classify the epilepsies Epilepsia, 2014; 55(8): 1139.
• Mathern Gary W, Beninsig Laurie, Nehlig Astrid   From the editors: our paper (first) anniversary and launching Epilepsia’s new look Epilepsia, 2014; 55(7): 949-55.
• Mathern Gary, Nehlig Astrid   From the editors: the discrepancy between accumulative incidence and lifetime prevalence of epilepsy Epilepsia, 2014; 55(7): 956-7.
• Mathern Gary, Nehlig Astrid, Sperling Michael   Cannabidiol and medical marijuana for the treatment of epilepsy Epilepsia, 2014; 55(6): 781-2.
• Mathern Gary, Nehlig Astrid   From the editors: Introducing Epilepsia’s Controversy in Epilepsy series Epilepsia, 2014; 55(5): 627-8.
• Jayakar Prasanna, Gaillard William D, Tripathi Manjari, Libenson Mark H, Mathern Gary W, Cross J Helen, Cross J Helen   Diagnostic test utilization in evaluation for resective epilepsy surgery in children Epilepsia, 2014; 55(4): 507-18.
• Fisher Robert S, Acevedo Carlos, Arzimanoglou Alexis, Bogacz Alicia, Cross J Helen, Elger Christian E, Engel Jerome, Forsgren Lars, French Jacqueline A, Glynn Mike, Hesdorffer Dale C, Lee B I, Mathern Gary W, Moshé Solomon L, Perucca Emilio, Scheffer Ingrid E, Tomson Torbjörn, Watanabe Masako, Wiebe Samuel   ILAE official report: a practical clinical definition of epilepsy Epilepsia, 2014; 55(4): 475-82.
• Mathern Gary, Nehlig Astrid   Editorial: reducing stigma by changing the name of epilepsy Epilepsia, 2014; 55(3): 383.
• Rosenow Felix, Alonso-Vanegas Mario A, Baumgartner Christoph, Blümcke Ingmar, Carreño Mar, Gizewski Elke R, Hamer Hajo M, Knake Susanne, Kahane Philippe, Lüders Hans O, Mathern Gary W, Menzler Katja, Miller Jonathan, Otsuki Taisuke, Ozkara Cigdem, Pitkänen Asla, Roper Steven N, Sakamoto Americo C, Sure Ulrich, Walker Matthew C, Steinhoff Bernhard J, Steinhoff Bernhard J   In response to commentary on cavernoma-related epilepsy: review and recommendations for management-report of the surgical task force of the ILAE commission on therapeutic strategies Epilepsia, 2014; 55(3): 466-7.
• Lewis Darrell V, Shinnar Shlomo, Hesdorffer Dale C, Bagiella Emilia, Bello Jacqueline A, Chan Stephen, Xu Yuan, MacFall James, Gomes William A, Moshé Solomon L, Mathern Gary W, Pellock John M, Nordli Douglas R, Frank L Matthew, Provenzale James, Shinnar Ruth C, Epstein Leon G, Masur David, Litherland Claire, Sun Shumei, Sun Shumei   Hippocampal sclerosis after febrile status epilepticus: the FEBSTAT study Annals of neurology, 2014; 75(2): 178-85.
• Cepeda Carlos, Chen Jane Y, Wu Joyce Y, Fisher Robin S, Vinters Harry V, Mathern Gary W, Levine Michael S   Pacemaker GABA synaptic activity may contribute to network synchronization in pediatric cortical dysplasia Neurobiology of disease, 2014; 62(2): 208-17.
• Varadkar Sophia, Bien Christian G, Kruse Carol A, Jensen Frances E, Bauer Jan, Pardo Carlos A, Vincent Angela, Mathern Gary W, Cross J Helen   Rasmussen’s encephalitis: clinical features, pathobiology, and treatment advances The Lancet. Neurology, 2014; 13(2): 195-205.
• Rosenow Felix, Alonso-Vanegas Mario A, Baumgartner Christoph, Blümcke Ingmar, Carreño Maria, Gizewski Elke R, Hamer Hajo M, Knake Susanne, Kahane Philippe, Lüders Hans O, Mathern Gary W, Menzler Katja, Miller Jonathan, Otsuki Taisuke, Ozkara Cigdem, Pitkänen Asla, Roper Steven N, Sakamoto Americo C, Sure Ulrich, Walker Matthew C, Steinhoff Bernhard J, Steinhoff Bernhard J   Cavernoma-related epilepsy: review and recommendations for management–report of the Surgical Task Force of the ILAE Commission on Therapeutic Strategies Epilepsia, 2013; 54(12): 2025-35.
• Phung Jennifer, Krogstad Paul, Mathern Gary W   Fevers and abnormal blood and cerebrospinal fluid studies after pediatric cerebral hemispherectomy: impact of etiology and age at surgery Journal of neurosurgery. Pediatrics, 2013; 12(6): 595-603.
• Mathern Gary W, Nehlig Astrid   Epilepsia editorial: publications by country Epilepsia, 2013; 54(11): 1849-50.
• Phung Jennifer, Krogstad Paul, Mathern Gary W   Etiology associated with developing posthemispherectomy hydrocephalus after resection-disconnection procedures Journal of neurosurgery. Pediatrics, 2013; 12(5): 469-75.
• Blümcke Ingmar, Thom Maria, Aronica Eleonora, Armstrong Dawna D, Bartolomei Fabrice, Bernasconi Andrea, Bernasconi Neda, Bien Christian G, Cendes Fernando, Coras Roland, Cross J Helen, Jacques Thomas S, Kahane Philippe, Mathern Gary W, Miyata Haijme, Moshé Solomon L, Oz Buge, Özkara Çiğdem, Perucca Emilio, Sisodiya Sanjay, Wiebe Samuel, Spreafico Roberto   International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods Epilepsia, 2013; 54(7): 1315-29.
• Mathern Gary W, Nehlig Astrid   Introduction of new Editors-in-Chief, Epilepsia Epilepsia, 2013; 54(7): 1141-2.
• Hauptman Jason S, Dadour Andrew, Oh Taemin, Baca Christine B, Vickrey Barbara G, Vassar Stefanie, Sankar Raman, Salamon Noriko, Vinters Harry V, Mathern Gary W   Time to pediatric epilepsy surgery is longer and developmental outcomes lower for government compared with private insurance Neurosurgery, 2013; 73(1): 152-7.
• Owens Geoffrey C, Huynh My N, Chang Julia W, McArthur David L, Hickey Michelle J, Vinters Harry V, Mathern Gary W, Kruse Carol A   Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response Journal of neuroinflammation, 2013; 10(5): 56.
• Akhtari Massoud, Pope Whitney, Mathern Gary, Moats Rex, Frew Andrew, Mandelkern Mark   Functionalized magnetonanoparticles in visualization of intracranial tumors on MRI Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2013; 15(3): 299-306.
• Sarafian Theodore A, Ryan Christopher M, Souda Puneet, Masliah Eliezer, Kar Upendra K, Vinters Harry V, Mathern Gary W, Faull Kym F, Whitelegge Julian P, Watson Joseph B   Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein PloS one, 2013; 8(5): e63557.
• Phung Jennifer, Mathern Gary W, Krogstad Paul   Timing and predictors of fever and infection after craniotomy for epilepsy in children The Pediatric infectious disease journal, 2013; 32(5): 450-9.
• Baek Seung Tae, Gibbs Elizabeth M, Gleeson Joseph G, Mathern Gary W   Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders Current opinion in neurology, 2013; 26(2): 122-7.
• Mathern Gary W, Miller John W   Outcomes for temporal lobe epilepsy operations may not be equal: a call for an RCT of ATL vs SAH Neurology, 2013; 80(18): 1630-1.
• Hauptman Jason S, Dadour Andrew, Oh Taemin, Baca Christine B, Vickrey Barbara G, Vassar Stefanie D, Sankar Raman, Salamon Noriko, Vinters Harry V, Mathern Gary W   Sociodemographic changes over 25 years of pediatric epilepsy surgery at UCLA Journal of neurosurgery. Pediatrics, 2013; 11(3): 250-5.
• Baca Christine B, Vickrey Barbara G, Vassar Stefanie, Hauptman Jason S, Dadour Andrew, Oh Taemin, Salamon Noriko, Vinters Harry V, Sankar Raman, Mathern Gary W   Time to pediatric epilepsy surgery is related to disease severity and nonclinical factors Neurology, 2013; 80(13): 1231-9.
• Hauptman Jason S, Pedram Kayvon, Sison Christia Angela, Sankar Raman, Salamon Noriko, Vinters Harry V, Mathern Gary W   Pediatric epilepsy surgery: long-term 5-year seizure remission and medication use Neurosurgery, 2012; 71(5): 985-93.
• Chang Julia W, Arnold Monica M, Rozenbaum Anna, Caputo Anna, Schweizer Felix E, Huynh My, Mathern Gary W, Sarafian Theodore A, Watson Joseph B   Synaptoneurosome micromethod for fractionation of mouse and human brain, and primary neuronal cultures Journal of neuroscience methods, 2012; 211(2): 289-95.
• de Bode Stella, Fritz Stacy, Mathern Gary W   Cerebral hemispherectomy: sensory scores before and after intensive mobility training Brain & development, 2012; 34(8): 625-31.
• Hauptman Jason S, Mathern Gary W   Surgical treatment of epilepsy associated with cortical dysplasia: 2012 update Epilepsia, 2012; 53 Suppl 4(8): 98-104.
• Langfitt John T, Mathern Gary W   Web-based eight-question tool to determine epilepsy surgery evaluation: the future is here Neurology, 2012; 79(11): 1074-5.
• Lee Jeong Ho, Huynh My, Silhavy Jennifer L, Kim Sangwoo, Dixon-Salazar Tracy, Heiberg Andrew, Scott Eric, Bafna Vineet, Hill Kiley J, Collazo Adrienne, Funari Vincent, Russ Carsten, Gabriel Stacey B, Mathern Gary W, Gleeson Joseph G   De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly Nature genetics, 2012; 44(8): 941-5.
• Wagner Aaron S, Yin Nicole S, Tung Spencer, Mathern Gary W, Vinters Harry V   Intimal thickening of meningeal arteries after serial corticectomies for Rasmussen encephalitis Human pathology, 2012; 43(8): 1308-13.
• Hauptman Jason S, Salamon Noriko, Mathern Gary W   Neuroimaging in the definition and organization of the epilepsies: we’re not there yet Epilepsia, 2012; 53 Suppl 2(8): 22-7.
• Cepeda Carlos, André Véronique M, Hauptman Jason S, Yamazaki Irene, Huynh My N, Chang Julia W, Chen Jane Y, Fisher Robin S, Vinters Harry V, Levine Michael S, Mathern Gary W   Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex Neurobiology of disease, 2012; 45(1): 310-21.
• Hauptman Jason S, Mathern Gary W   Epilepsy neurosurgery in children Handbook of clinical neurology, 2012; 108(1): 881-95.
• Moshé Solomon L, Perucca Emilio, Wiebe Samuel, Mathern Gary W   The International League Against Epilepsy at the threshold of its second century: year 2 Epilepsia, 2012; 53(1): 215-9.
• Hauptman Jason S, Mathern Gary W   Vagal nerve stimulation for pharmacoresistant epilepsy in children Surgical neurology international, 2012; 3(Suppl 4): S269-74.
• Velasco Tonicarlo R, Wichert-Ana Lauro, Mathern Gary W, Araújo David, Walz Roger, Bianchin Marino M, Dalmagro Charles L, Leite Joao P, Santos Antonio C, Assirati Joao A, Carlotti Carlos G, Sakamoto Americo C   Utility of ictal single photon emission computed tomography in mesial temporal lobe epilepsy with hippocampal atrophy: a randomized trial Neurosurgery, 2011; 68(2): 431-6; discussion 436.
• Moshé Solomon L, Perucca Emilio, Wiebe Samuel, Mathern Gary W   The International League Against Epilepsy at the threshold of its second century: year 1 Epilepsia, 2011; 52(1): 185-7.
• Blümcke Ingmar, Thom Maria, Aronica Eleonora, Armstrong Dawna D, Vinters Harry V, Palmini Andre, Jacques Thomas S, Avanzini Giuliano, Barkovich A James, Battaglia Giorgio, Becker Albert, Cepeda Carlos, Cendes Fernando, Colombo Nadia, Crino Peter, Cross J Helen, Delalande Olivier, Dubeau François, Duncan John, Guerrini Renzo, Kahane Philippe, Mathern Gary, Najm Imad, Ozkara Ciğdem, Raybaud Charles, Represa Alfonso, Roper Steven N, Salamon Noriko, Schulze-Bonhage Andreas, Tassi Laura, Vezzani Annamaria, Spreafico Roberto   The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission Epilepsia, 2011; 52(1): 158-74.
• Qin Wei, Chan Jennifer A, Vinters Harry V, Mathern Gary W, Franz David N, Taillon Bruce E, Bouffard Pascal, Kwiatkowski David J   Analysis of TSC cortical tubers by deep sequencing of TSC1, TSC2 and KRAS demonstrates that small second-hit mutations in these genes are rare events Brain pathology (Zurich, Switzerland), 2010; 20(6): 1096-105.
• Mathern Gary W   Cerebral hemispherectomy: when half a brain is good enough Neurology, 2010; 75(18): 1578-80.
• Thom Maria, Mathern Gary W, Cross J Helen, Bertram Edward H   Mesial temporal lobe epilepsy: How do we improve surgical outcome? Annals of neurology, 2010; 68(4): 424-34.
• Cepeda Carlos, André Véronique M, Yamazaki Irene, Hauptman Jason S, Chen Jane Y, Vinters Harry V, Mathern Gary W, Levine Michael S   Comparative study of cellular and synaptic abnormalities in brain tissue samples from pediatric tuberous sclerosis complex and cortical dysplasia type II Epilepsia, 2010; 51 Suppl 3(4): 160-5.
• André Véronique M, Cepeda Carlos, Vinters Harry V, Huynh My, Mathern Gary W, Levine Michael S   Interneurons, GABAA currents, and subunit composition of the GABAA receptor in type I and type II cortical dysplasia Epilepsia, 2010; 51 Suppl 3(4): 166-70.
• Kwan Patrick, Arzimanoglou Alexis, Berg Anne T, Brodie Martin J, Allen Hauser W, Mathern Gary, Moshé Solomon L, Perucca Emilio, Wiebe Samuel, French Jacqueline   Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies Epilepsia, 2010; 51(6): 1069-77.
• Berg Anne T, Berkovic Samuel F, Brodie Martin J, Buchhalter Jeffrey, Cross J Helen, van Emde Boas Walter, Engel Jerome, French Jacqueline, Glauser Tracy A, Mathern Gary W, Moshé Solomon L, Nordli Douglas, Plouin Perrine, Scheffer Ingrid E   Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009 Epilepsia, 2010; 51(4): 676-85.
• Mathern Gary W   Commentary Surgical neurology, 2009; 72(6): 591.
• Mehta Rupal I, Cutler Aaron R, Lasky Joseph L, Yong William H, Lerner Jason T, Hirota Brandon K, Salamon Noriko, Mathern Gary W, Vinters Harry V   “Primary” leptomeningeal medulloblastoma Human pathology, 2009; 40(11): 1661-5.
• Mathern Gary W   Challenges in the surgical treatment of epilepsy patients with cortical dysplasia Epilepsia, 2009; 50 Suppl 9(Pt 10): 45-50.
• Berg Anne T, Mathern Gary W, Bronen Richard A, Fulbright Robert K, DiMario Francis, Testa Francine M, Levy Susan R   Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy Brain : a journal of neurology, 2009; 132(Pt 10): 2785-97.
• Khanlou Négar, Mathern Gary W, Mitchell Wendy G, Salamon Noriko, Pope Whitney B, Yong William H, Vinters Harry V   Cortical dysplasia with prominent Rosenthal fiber formation in a case of intractable pediatric epilepsy Human pathology, 2009; 40(8): 1200-4.
• Lerner Jason T, Salamon Noriko, Hauptman Jason S, Velasco Tonicarlo R, Hemb Marta, Wu Joyce Y, Sankar Raman, Donald Shields W, Engel Jerome, Fried Itzhak, Cepeda Carlos, Andre Veronique M, Levine Michael S, Miyata Hajime, Yong William H, Vinters Harry V, Mathern Gary W   Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience Epilepsia, 2009; 50(6): 1310-35.
• Wirenfeldt Martin, Clare Ryan, Tung Spencer, Bottini Alexander, Mathern Gary W, Vinters Harry V   Increased activation of Iba1+ microglia in pediatric epilepsy patients with Rasmussen’s encephalitis compared with cortical dysplasia and tuberous sclerosis complex Neurobiology of disease, 2009; 34(3): 432-40.
• de Bode Stella, Fritz Stacy L, Weir-Haynes Kristi, Mathern Gary W   Constraint-induced movement therapy for individuals after cerebral hemispherectomy: a case series Physical therapy, 2009; 89(4): 361-9.
• Mathern Gary W   Epilepsy surgery patients with cortical dysplasia: present and future therapeutic challenges Neurology, 2009; 72(3): 206-7.
• Wu Joyce Y, Koh Susan, Sankar Raman, Mathern Gary W   Paroxysmal fast activity: an interictal scalp EEG marker of epileptogenesis in children Epilepsy research, 2008; 82(1): 99-106.
• André Véronique M, Cepeda Carlos, Vinters Harry V, Huynh My, Mathern Gary W, Levine Michael S   Pyramidal cell responses to gamma-aminobutyric acid differ in type I and type II cortical dysplasia Journal of neuroscience research, 2008; 86(14): 3151-62.
• Harvey A Simon, Cross J Helen, Shinnar Shlomo, Mathern Gary W, Mathern Bary W, Mathern Bary W   Defining the spectrum of international practice in pediatric epilepsy surgery patients Epilepsia, 2008; 49(1): 146-55.
• Staba Richard J, Frighetto Leonardo, Behnke Eric J, Mathern Gary W, Fields Tony, Bragin Anatol, Ogren Jennifer, Fried Itzhak, Wilson Charles L, Engel Jerome   Increased fast ripple to ripple ratios correlate with reduced hippocampal volumes and neuron loss in temporal lobe epilepsy patients Epilepsia, 2007; 48(11): 2130-8.
• de Bode Stella, Mathern Gary W, Bookheimer Susan, Dobkin Bruce   Locomotor training remodels fMRI sensorimotor cortical activations in children after cerebral hemispherectomy Neurorehabilitation and neural repair, 2007; 21(6): 497-508.
• Mathern Gary W, Andres Marissa, Salamon Noriko, Chandra P Sarat, Andre Veronique M, Cepeda Carlos, Levine Michael S, Leite Joao P, Neder Luciano, Vinters Harry V   A hypothesis regarding the pathogenesis and epileptogenesis of pediatric cortical dysplasia and hemimegalencephaly based on MRI cerebral volumes and NeuN cortical cell densities Epilepsia, 2007; 48 Suppl 5(6): 74-8.
• André Véronique M, Wu Nanping, Yamazaki Irene, Nguyen Snow T, Fisher Robin S, Vinters Harry V, Mathern Gary W, Levine Michael S, Cepeda Carlos   Cytomegalic interneurons: a new abnormal cell type in severe pediatric cortical dysplasia Journal of neuropathology and experimental neurology, 2007; 66(6): 491-504.
• de Bode Stella, Sininger Yvonne, Healy Eric W, Mathern Gary W, Zaidel Eran   Dichotic listening after cerebral hemispherectomy: methodological and theoretical observations Neuropsychologia, 2007; 45(11): 2461-6.
• Cepeda Carlos, André Véronique M, Wu Nanping, Yamazaki Irene, Uzgil Besim, Vinters Harry V, Levine Michael S, Mathern Gary W   Immature neurons and GABA networks may contribute to epileptogenesis in pediatric cortical dysplasia Epilepsia, 2007; 48 Suppl 5(6): 79-85.
• Mathern Gary W, Trevathan Edwin   Childhood-onset temporal lobe epilepsy: neuroimaging predicts seizure control Neurology, 2006; 67(12): 2117-8.
• Huang Susie Y, Wolahan Stephanie M, Mathern Gary W, Chute Dennis J, Akhtari Massoud, Nguyen Snow T, Huynh My N, Salamon Noriko, Lin Yung-Ya   Improving MRI differentiation of gray and white matter in epileptogenic lesions based on nonlinear feedback Magnetic resonance in medicine, 2006; 56(4): 776-86.
• Cepeda Carlos, André Véronique M, Levine Michael S, Salamon Noriko, Miyata Hajime, Vinters Harry V, Mathern Gary W   Epileptogenesis in pediatric cortical dysplasia: the dysmature cerebral developmental hypothesis Epilepsy & behavior : E&B, 2006; 9(2): 219-35.
• Chandra Poodipedi S, Salamon Noriko, Huang Jimmy, Wu Joyce Y, Koh Susan, Vinters Harry V, Mathern Gary W   FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex: a preliminary report Epilepsia, 2006; 47(9): 1543-9.
• Cross J Helen, Jayakar Prasanna, Nordli Doug, Delalande Olivier, Duchowny Michael, Wieser Heinz G, Guerrini Renzo, Mathern Gary W, Mathern Gary W, Mathern Gary W   Proposed criteria for referral and evaluation of children for epilepsy surgery: recommendations of the Subcommission for Pediatric Epilepsy Surgery Epilepsia, 2006; 47(6): 952-9.
• Salamon Noriko, Andres Marissa, Chute Dennis J, Nguyen Snow T, Chang Julia W, Huynh My N, Chandra P Sarat, Andre Veronique M, Cepeda Carlos, Levine Michael S, Leite Joao P, Neder Luciano, Vinters Harry V, Mathern Gary W   Contralateral hemimicrencephaly and clinical-pathological correlations in children with hemimegalencephaly Brain : a journal of neurology, 2006; 129(Pt 2): 352-65.
• Leppik Ilo E, Kelly Kevin M, deToledo-Morrell Leyla, Patrylo Peter R, DeLorenzo Robert J, Mathern Gary W, White H Steve   Basic research in epilepsy and aging Epilepsy research, 2006; 68 Suppl 1(Pt 2): S21-37.
• Koh Susan, Mathern Gary W, Glasser Gabrielle, Wu Joyce Y, Shields W Donald, Jonas Rinat, Yudovin Sue, Cepeda Carlos, Salamon Noriko, Vinters Harry V, Sankar Raman   Status epilepticus and frequent seizures: incidence and clinical characteristics in pediatric epilepsy surgery patients Epilepsia, 2005; 46(12): 1950-4.
• Cepeda, C. Andre, V. M. Vinters, H. V. Levine, M. S. Mathern, G. W.   Are cytomegalic neurons and balloon cells generators of epileptic activity in pediatric cortical dysplasia? Epilepsia, 2005; 46 Suppl 5: 82-8.
• Cepeda, C. Andre, V. M. Flores-Hernandez, J. Nguyen, O. K. Wu, N. Klapstein, G. J. Nguyen, S. Koh, S. Vinters, H. V. Levine, M. S. Mathern, G. W.   Pediatric cortical dysplasia: correlations between neuroimaging, electrophysiology and location of cytomegalic neurons and balloon cells and glutamate/GABA synaptic circuits Dev Neurosci, 2005; 27(1): 59-76.
• Jonas, R Asarnow, RF LoPresti, C Yudovin, S Koh, S Wu, JY Sankar, R Shields, WD Vinters, HV Mathern, GW   Surgery for symptomatic infant-onset epileptic encephalopathy with and without infantile spasms Neurology. , 2005; 64(4): 746-50.
• Andres, M Andre, VM Nguyen, S Salamon, N Cepeda, C Levine, MS Leite, JP Neder, L Vinters, HV Mathern, GW   Human cortical dysplasia and epilepsy: an ontogenetic hypothesis based on volumetric MRI and NeuN neuronal density and size measurements Cerebral cortex (New York, N.Y. : 1991) , 2005; 15(2): 194-210.
• de Bode, S Firestine, A Mathern, GW Dobkin, B   Residual motor control and cortical representations of function following hemispherectomy: effects of etiology Journal of child neurology. , 2005; 20(1): 64-75.
• Koh, S. Nguyen, S. Asarnow, R. F. LoPresti, C. Yudovin, S. Shields, W. D. Vinters, H. V. Mathern, G. W.   Five or more acute postoperative seizures predict hospital course and long-term seizure control after hemispherectomy Epilepsia, 2004; 45(5): 527-33.
• Andre, V. M. Flores-Hernandez, J. Cepeda, C. Starling, A. J. Nguyen, S. Lobo, M. K. Vinters, H. V. Levine, M. S. Mathern, G. W.   NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue Cereb Cortex, 2004; 14(6): 634-46.
• Jonas, R Nguyen, S Hu, B Asarnow, RF LoPresti, C Curtiss, S de Bode, S Yudovin, S Shields, WD Vinters, HV Mathern, GW   Cerebral hemispherectomy: hospital course, seizure, developmental, language, and motor outcomes Neurology. , 2004; 62(10): 1712-21.
• Najm, I Ying, Z Babb, T Crino, PB Macdonald, R Mathern, GW Spreafico, R   Mechanisms of epileptogenicity in cortical dysplasias Neurology. , 2004; 62(6 Suppl 3): S9-13.
• Cook, SW Nguyen, ST Hu, B Yudovin, S Shields, WD Vinters, HV Van de Wiele, BM Harrison, RE Mathern, GW   Cerebral hemispherectomy in pediatric patients with epilepsy: comparison of three techniques by pathological substrate in 115 patients Journal of neurosurgery. , 2004; 100(2 Suppl Pediatrics): 125-41.
• Stables, JP Bertram, E Dudek, FE Holmes, G Mathern, G Pitkanen, A White, HS   Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop Epilepsia. , 2003; 44(12): 1472-8.
• Handforth, A Ondo, WG Tatter, S Mathern, GW Simpson, RK Walker, F Sutton, JP Hubble, JP Jankovic, J   Vagus nerve stimulation for essential tremor: a pilot efficacy and safety trial Neurology. , 2003; 61(10): 1401-5.
• Bender, RA Soleymani, SV Brewster, AL Nguyen, ST Beck, H Mathern, GW Baram, TZ   Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus The Journal of neuroscience : the official journal of the Society for Neuroscience. , 2003; 23(17): 6826-36.
• Cepeda, C. Hurst, R. S. Flores-Hernandez, J. Hernandez-Echeagaray, E. Klapstein, G. J. Boylan, M. K. Calvert, C. R. Jocoy, E. L. Nguyen, O. K. Andre, V. M. Vinters, H. V. Ariano, M. A. Levine, M. S. Mathern, G. W.   Morphological and electrophysiological characterization of abnormal cell types in pediatric cortical dysplasia J Neurosci Res, 2003; 72(4): 472-86.
• Caplan, R. Siddarth, P. Mathern, G. Vinters, H. Curtiss, S. Levitt, J. Asarnow, R. Shields, W. D.   Developmental outcome with and without successful intervention Int Rev Neurobiol, 2002; 49: 269-84.
• Mathern, GW Adelson, PD Cahan, LD Leite, JP   Hippocampal neuron damage in human epilepsy: Meyer’s hypothesis revisited Progress in brain research. , 2002; 135: 237-51.
• Mathern, GW Leiphart, JL De Vera, A Adelson, PD Seki, T Neder, L Leite, JP   Seizures decrease postnatal neurogenesis and granule cell development in the human fascia dentata Epilepsia. , 2002; 43 Suppl 5: 68-73.
• Shusta, E. V. Boado, R. J. Mathern, G. W. Pardridge, W. M.   Vascular genomics of the human brain J Cereb Blood Flow Metab, 2002; 22(3): 245-52.
• Curtiss, S de Bode, S Mathern, GW   Spoken language outcomes after hemispherectomy: factoring in etiology Brain and language. , 2001; 79(3): 379-96.
• Leiphart, JW Peacock, WJ Mathern, GW   Lobar and multilobar resections for medically intractable pediatric epilepsy Pediatric neurosurgery. , 2001; 34(6): 311-8.
• Katzir, H Mendoza, D Mathern, GW   Effect of theophylline and trimethobenzamide when given during kainate-induced status epilepticus: an improved histopathologic rat model of human hippocampal sclerosis Epilepsia. , 2000; 41(11): 1390-9.
• Mathern, GW Cepeda, C Hurst, RS Flores-Hernandez, J Mendoza, D Levine, MS   Neurons recorded from pediatric epilepsy surgery patients with cortical dysplasia Epilepsia. , 2000; 41 Suppl 6: S162-7.
• Mathern, GW Giza, CC Yudovin, S Vinters, HV Peacock, WJ Shewmon, DA Shields, WD   Postoperative seizure control and antiepileptic drug use in pediatric epilepsy surgery patients: the UCLA experience, 1986-1997 Epilepsia. , 1999; 40(12): 1740-9.
• Kerfoot, C Vinters, HV Mathern, GW   Cerebral cortical dysplasia: giant neurons show potential for increased excitation and axonal plasticity Developmental neuroscience. , 1999; 21(3-5): 260-70.
• Isokawa, M Mathern, GW   Developmental changes in NMDA-induced intrinsic optical signals in the hippocampal dentate gyrus of children with medically intractable seizures Developmental neuroscience. , 1999; 21(3-5): 215-22.
• Cepeda, C Li, Z Cromwell, HC Altemus, KL Crawford, CA Nansen, EA Ariano, MA Sibley, DR Peacock, WJ Mathern, GW Levine, MS   Electrophysiological and morphological analyses of cortical neurons obtained from children with catastrophic epilepsy: dopamine receptor modulation of glutamatergic responses Developmental neuroscience. , 1999; 21(3-5): 223-35.
• Bragin, A Engel, J Wilson, CL Vizentin, E Mathern, GW   Electrophysiologic analysis of a chronic seizure model after unilateral hippocampal KA injection Epilepsia. , 1999; 40(9): 1210-21.
• Mathern, GW Pretorius, JK Mendoza, D Leite, JP Chimelli, L Born, DE Fried, I Assirati, JA Ojemann, GA Adelson, PD Cahan, LD Kornblum, HI   Hippocampal N-methyl-D-aspartate receptor subunit mRNA levels in temporal lobe epilepsy patients Annals of neurology. , 1999; 46(3): 343-58.
• Mathern, GW Mendoza, D Lozada, A Pretorius, JK Dehnes, Y Danbolt, NC Nelson, N Leite, JP Chimelli, L Born, DE Sakamoto, AC Assirati, JA Fried, I Peacock, WJ Ojemann, GA Adelson, PD   Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy Neurology. , 1999; 52(3): 453-72.
• Bragin, A Engel, J Wilson, CL Fried, I Mathern, GW   Hippocampal and entorhinal cortex high-frequency oscillations (100–500 Hz) in human epileptic brain and in kainic acid–treated rats with chronic seizures Epilepsia. , 1999; 40(2): 127-37.
• Mathern, GW Pretorius, JK Mendoza, D Lozada, A Kornblum, HI   Hippocampal AMPA and NMDA mRNA levels correlate with aberrant fascia dentata mossy fiber sprouting in the pilocarpine model of spontaneous limbic epilepsy Journal of neuroscience research. , 1998; 54(6): 734-53.
• Mathern, GW Pretorius, JK Kornblum, HI Mendoza, D Lozada, A Leite, JP Chimelli, L Born, DE Fried, I Sakamoto, AC Assirati, JA Peacock, WJ Ojemann, GA Adelson, PD   Altered hippocampal kainate-receptor mRNA levels in temporal lobe epilepsy patients Neurobiology of disease. , 1998; 5(3): 151-76.
• Mathern, GW Pretorius, JK Leite, JP Kornblum, HI Mendoza, D Lozada, A Bertram, EH   Hippocampal AMPA and NMDA mRNA levels and subunit immunoreactivity in human temporal lobe epilepsy patients and a rodent model of chronic mesial limbic epilepsy Epilepsy research. , 1998; 32(1-2): 154-71.
• Mathern, GW Pretorius, JK Mendoza, D Lozada, A Leite, JP Chimelli, L Fried, I Sakamoto, AC Assirati, JA Adelson, PD   Increased hippocampal AMPA and NMDA receptor subunit immunoreactivity in temporal lobe epilepsy patients Journal of neuropathology and experimental neurology. , 1998; 57(6): 615-34.
• Mathern, GW Price, G Rosales, C Pretorius, JK Lozada, A Mendoza, D   Anoxia during kainate status epilepticus shortens behavioral convulsions but generates hippocampal neuron loss and supragranular mossy fiber sprouting Epilepsy research. , 1998; 30(2): 133-51.
• Mathern, GW Pretorius, JK Kornblum, HI Mendoza, D Lozada, A Leite, JP Chimelli, LM Fried, I Sakamoto, AC Assirati, JA Lévesque, MF Adelson, PD Peacock, WJ   Human hippocampal AMPA and NMDA mRNA levels in temporal lobe epilepsy patients Brain : a journal of neurology. , 1997; 120 ( Pt 11): 1937-59.
• Mathern, GW Babb, TL Micevych, PE Blanco, CE Pretorius, JK   Granule cell mRNA levels for BDNF, NGF, and NT-3 correlate with neuron losses or supragranular mossy fiber sprouting in the chronically damaged and epileptic human hippocampus Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid. , 1997; 30(1-2): 53-76.
• Mathern, GW Bertram, EH Babb, TL Pretorius, JK Kuhlman, PA Spradlin, S Mendoza, D   In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for N-methyl-D-aspartate, AMPA and GABA(A) receptors Neuroscience. , 1997; 77(4): 1003-19.
• Mathern, GW Kuhlman, PA Mendoza, D Pretorius, JK   Human fascia dentata anatomy and hippocampal neuron densities differ depending on the epileptic syndrome and age at first seizure Journal of neuropathology and experimental neurology. , 1997; 56(2): 199-212.
• Babb, TL Mathern, GW Leite, JP Pretorius, JK Yeoman, KM Kuhlman, PA   Glutamate AMPA receptors in the fascia dentata of human and kainate rat hippocampal epilepsy Epilepsy research. , 1996; 26(1): 193-205.
• Leite, JP Babb, TL Pretorius, JK Kuhlman, PA Yeoman, KM Mathern, GW   Neuron loss, mossy fiber sprouting, and interictal spikes after intrahippocampal kainate in developing rats Epilepsy research. , 1996; 26(1): 219-31.
• Mathern, GW Babb, TL Leite, JP Pretorius, K Yeoman, KM Kuhlman, PA   The pathogenic and progressive features of chronic human hippocampal epilepsy Epilepsy research. , 1996; 26(1): 151-61.
• Babb, TL Mathern, GW Pretorius, JK Cifuentes, F   Astrocytes may contribute to the latent period in progressive neuron loss, axon sprouting, and chronic seizures in rat kainate hippocampal epilepsy Epilepsy research. Supplement. , 1996; 12: 343-54.
• Mathern, G. W. Leite, J. P. Pretorius, J. K. Quinn, B. Peacock, W. J. Babb, T. L.   Severe seizures in young children are associated with hippocampal neuron losses and aberrant mossy fiber sprouting during fascia dentata postnatal development Epilepsy Res Suppl, 1996; 12: 33-43.
• Mathern, GW Babb, TL Mischel, PS Vinters, HV Pretorius, JK Leite, JP Peacock, WJ   Childhood generalized and mesial temporal epilepsies demonstrate different amounts and patterns of hippocampal neuron loss and mossy fibre synaptic reorganization Brain : a journal of neurology. , 1996; 119 ( Pt 3): 965-87.
• Mathern, GW Leite, JP Babb, TL Pretorius, JK Kuhlman, PA Mendoza, D Fried, I Sakamoto, AC Assirati, JA Adelson, PD Peacock, WJ   Aberrant hippocampal mossy fiber sprouting correlates with greater NMDAR2 receptor staining Neuroreport. , 1996; 7(5): 1029-35.
• Babb, TL Pereira-Leite, J Mathern, GW Pretorius, JK   Kainic acid induced hippocampal seizures in rats: comparisons of acute and chronic seizures using intrahippocampal versus systemic injections Italian journal of neurological sciences. , 1995; 16(1-2): 39-44.
• Mathern, G. W. Babb, T. L. Pretorius, J. K. Melendez, M. Levesque, M. F.   The pathophysiologic relationships between lesion pathology, intracranial ictal EEG onsets, and hippocampal neuron losses in temporal lobe epilepsy Epilepsy Res, 1995; 21(2): 133-47.
• Mathern, GW Babb, TL Pretorius, JK Leite, JP   Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata The Journal of neuroscience : the official journal of the Society for Neuroscience. , 1995; 15(5 Pt 2): 3990-4004.
• Mathern, GW Pretorius, JK Babb, TL   Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures Journal of neurosurgery. , 1995; 82(2): 220-7.
• Mathern, GW Pretorius, JK Babb, TL   Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures Journal of neurosurgery. , 1995; 82(2): 211-9.
• Mathern, GW Babb, TL Vickrey, BG Melendez, M Pretorius, JK   The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy Brain : a journal of neurology. , 1995; 118 ( Pt 1): 105-18.
• Mathern, GW Pretorius, JK Babb, TL Quinn, B   Unilateral hippocampal mossy fiber sprouting and bilateral asymmetric neuron loss with episodic postictal psychosis Journal of neurosurgery. , 1995; 82(2): 228-33.
• Mathern, GW Babb, TL Vickrey, BG Melendez, M Pretorius, JK   Traumatic compared to non-traumatic clinical-pathologic associations in temporal lobe epilepsy Epilepsy research. , 1994; 19(2): 129-39.
• Mathern, GW Leite, JP Pretorius, JK Quinn, B Peacock, WJ Babb, TL   Children with severe epilepsy: evidence of hippocampal neuron losses and aberrant mossy fiber sprouting during postnatal granule cell migration and differentiation Brain research. Developmental brain research. , 1994; 78(1): 70-80.
• Mathern, GW Cifuentes, F Leite, JP Pretorius, JK Babb, TL   Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model Electroencephalography and clinical neurophysiology. , 1993; 87(5): 326-39.
• Babb, TL Pretorius, JK Mello, LE Mathern, GW Levesque, MF   Synaptic reorganizations in epileptic human and rat kainate hippocampus may contribute to feedback and feedforward excitation Epilepsy research. Supplement. , 1992; 9: 193-202; discussion 203.
• Schell, RE Mathern, GW   Complication in nasogastric tube placement after a gunshot wound to the face Oral surgery, oral medicine, and oral pathology. , 1990; 70(4): 525-6.
• Mathern, GW Batzdorf, U   Grisel’s syndrome. Cervical spine clinical, pathologic, and neurologic manifestations Clinical orthopaedics and related research. , 1989; (244): 131-46.