George Wasonga Agak
Associate Professor-in-residence, Medicine, University of California Los Angeles
gagak@mednet.ucla.edu
Publications
- Qin M, Evron E, Tran PT, Deng M, Nelson AM, Kim J, Agak GW. Immune activation and glycolytic responses to Cutibacterium acnes cell wall polysaccharides.. The Journal of investigative dermatology, 2025.
- Del Vecchio G, Nguyen NPN, Ouyang K, Odhiambo CO, Nelson AM, Deng M, Pellegrini M, Agak GW. Functional Dynamics of Dendritic Cells in Response to Cutibacteriumacnes Strains Associated with Healthy and Acne-Prone Skin.. The Journal of investigative dermatology, 2025.
- Patel R, Romero AG, Bryant AS, Agak GW, Hallem EA. Dopamine signaling drives skin invasion by human-infective nematodes.. bioRxiv : the preprint server for biology, 2025.
- Deng M, Farahani K, Agak GW. Insights into early acne pathogenesis: Exploring intercellular dynamics and key dysregulated genes.. Cell signaling, 2025.
- Sennett ML, Agak GW, Thiboutot DM, Nelson AM. Transcriptomic Analyses Predict Enhanced Metabolic Activity and Therapeutic Potential of mTOR Inhibitors in Acne-Prone Skin.. JID innovations : skin science from molecules to population health, 2024.
- Deng M, Odhiambo WO, Qin M, To TT, Brewer GM, Kheshvadjian AR, Cheng C, Agak GW. Analysis of intracellular communication reveals consistent gene changes associated with early-stage acne skin.. Cell communication and signaling : CCS, 2024.
- Deng M, Odhiambo WO, Qin M, To TT, Brewer GM, Kheshvadjian AR, Cheng C, Agak GW. Analysis of Intracellular Communication Reveals Consistent Gene Changes Associated with Early-Stage Acne Skin.. Research square, 2024.
- To TT, Oparaugo NC, Kheshvadjian AR, Nelson AM, Agak GW. Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection.. International journal of molecular sciences, 2024.
- Agak GW, Thiboutot DM, Zaenglein AL, Nelson AM. SLST D1 strains may contribute to skin health.. Experimental dermatology, 2023.
- Nolan ZT, Banerjee K, Cong Z, Gettle SL, Longenecker AL, Kawasawa YI, Zaenglein AL, Thiboutot DM, Agak GW, Zhan X, Nelson AM. Treatment response to isotretinoin correlates with specific shifts in Cutibacterium acnes strain composition within the follicular microbiome.. Experimental dermatology, 2023.
- Oparaugo NC, Ouyang K, Nguyen NPN, Nelson AM, Agak GW. Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers.. International journal of molecular sciences, 2023.
- Konate D, Diawara SI, Sogoba N, Shaffer J, Keita B, Cisse A, Sanogo I, Dicko I, Guindo MDA, Balam S, Traore A, Kante S, Dembele A, Kasse F, Denou L, Diakite SAS, Traore K, M'Baye Thiam S, Sanogo V, Toure M, Diarra A, Agak GW, Doumbia S, Diakite M. Effect of a fifth round of seasonal malaria chemoprevention in children aged 5-14 years in Dangassa, an area of long transmission in Mali.. Parasite epidemiology and control, 2023.
- Nguyen NPN, Oparaugo NC, Ouyang K, Agak GW. A protocol to detect human CD4+ T cell extracellular traps using scanning electron microscopy.. STAR protocols, 2022.
- Nang'ole WF, Omu A, Ogeng'o JA, Agak GW. Do Mesenchymal Stem Cells Influence Keloid Recurrence?. Stem cells and cloning : advances and applications, 2022.
- Ouyang K, Zheng DX, Agak GW. T-Cell Mediated Immunity in Merkel Cell Carcinoma.. Cancers, 2022.
- Schneider AM, Nolan ZT, Banerjee K, Paine AR, Cong Z, Gettle SL, Longenecker AL, Zhan X, Agak GW, Nelson AM. Evolution of the facial skin microbiome during puberty in normal and acne skin.. Journal of the European Academy of Dermatology and Venereology : JEADV, 2022.
- Ouyang K, Oparaugo N, Nelson AM, Agak GW. T Cell Extracellular Traps: Tipping the Balance Between Skin Health and Disease.. Frontiers in immunology, 2022.
- Nangole FW, Agak G. The effects of negative pressure wound therapy on wounds with cerebrospinal fluid leakages.. Journal of wound care, 2022.
- Wanjala NF, Joseph G, Anthony M, Primus O, Ogeng'o JJ, Anzala O, Dohil I, Agak GW. Keloids: Does patients' sex influence the presentation and recurrence post-excision?. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2021.
- Nangole FW, Ouyang K, Anzala O, Ogeng'o J, Agak GW, Zuriel D. Does Keloid Histology Influence Recurrence?. The American Journal of dermatopathology, 2021.
- Nangole FW, Ouyang K, Anzala O, Ogengo J, Agak GW. Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?. Journal of inflammation research, 2021.
- Agak GW, Mouton A, Teles RM, Weston T, Morselli M, Andrade PR, Pellegrini M, Modlin RL. Extracellular traps released by antimicrobial TH17 cells contribute to host defense.. The Journal of clinical investigation, 2021.
- Nangole FW, Agak GW. Keloid pathophysiology: fibroblast or inflammatory disorders?. JPRAS open, 2019.
- Park AJ, Agak GW, Qin M, Hisaw LD, Pirouz A, Kao S, Marinelli LJ, Garbán HJ, Thiboutot D, Liu PT, Kim J. G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes.. Annals of dermatology, 2017.
- Agak GW, Kao S, Ouyang K, Qin M, Moon D, Butt A, Kim J. Phenotype and Antimicrobial Activity of Th17 Cells Induced by Propionibacterium acnes Strains Associated with Healthy and Acne Skin.. The Journal of investigative dermatology, 2017.
- Yu Y, Champer J, Agak GW, Kao S, Modlin RL, Kim J. Different Propionibacterium acnes Phylotypes Induce Distinct Immune Responses and Express Unique Surface and Secreted Proteomes.. The Journal of investigative dermatology, 2016.
- Hisaw LD, Qin M, Park A, Agak GW, Pirouz A, Phan J, Fernandez C, Garbán HJ, Nelson A, Thiboutot D, Kim J. Antimicrobial Activity of Sebocytes against Propionibacterium acnes via Toll-Like Receptor 2 and Lysosomal Pathway.. The Journal of investigative dermatology, 2016.
- Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J, Friedman AJ. Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response.. The Journal of investigative dermatology, 2015.
- Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL. Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes.. The Journal of investigative dermatology, 2015.
- Agak GW, Qin M, Nobe J, Kim MH, Krutzik SR, Tristan GR, Elashoff D, Garbán HJ, Kim J. Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D.. The Journal of investigative dermatology, 2013.
- Olugbile S, Villard V, Bertholet S, Jafarshad A, Kulangara C, Roussilhon C, Frank G, Agak GW, Felger I, Nebie I, Konate K, Kajava AV, Schuck P, Druilhe P, Spertini F, Corradin G. Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope.. Vaccine, 2011.
- Agak GW, Bejon P, Fegan G, Gicheru N, Villard V, Kajava AV, Marsh K, Corradin G. Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya.. Vaccine, 2008.
- Villard V, Agak GW, Frank G, Jafarshad A, Servis C, Nébié I, Sirima SB, Felger I, Arevalo-Herrera M, Herrera S, Heitz F, Bäcker V, Druilhe P, Kajava AV, Corradin G. Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.. PloS one, 2007.