
Holly R Middlekauff
Professor, Medicine, University of California Los Angeles
Professor, Physiology, University of California Los Angeles
hmiddlekauff@mednet.ucla.edu
Mailing Address:
47-123 CHS
Office Address:
42-237 CHS
Los Angeles, CA
Affiliations
Member, Adult Cardiac Catheterization Laboratory, Molecular, Cellular & Integrative Physiology GPB Home Area
Faculty, Cardiology
Faculty, Cardiology
Publications
- Ruedisueli I, Lakhani K, Nguyen R, Gornbein J, Middlekauff HR. Electronic cigarettes prolong ventricular repolarization in people who smoke tobacco cigarettes: Implications for harm reduction.. American journal of physiology. Heart and circulatory physiology, 2023.
- Youn JY, Middlekauff HR, Reudiseuli I, Huang K, Cai H. Endothelial damage in young adult e-cigarette users.. Redox biology, 2023.
- Vuong JT, Ruedisueli I, Beaudin CS, Middlekauff HR. Electronic Cigarettes: an Overlooked Tool to Alleviate Disparities in Tobacco Use Disorder Among People with Mental Health and Substance Use Disorders.. Journal of general internal medicine, 2023.
- Kelesidis T, Sharma M, Satta S, Tran E, Gupta R, Araujo JA, Middlekauff HR. Ectodomain shedding of proteins important for SARS-CoV-2 pathogenesis in plasma of tobacco cigarette smokers compared to electronic cigarette vapers: a cross-sectional study.. Journal of molecular medicine (Berlin, Germany), 2023.
- Ruedisueli I, Arastoo S, Gupta PK, Gornbein J, Middlekauff HR. Neural-hematopoietic-inflammatory axis in nonsmokers, electronic cigarette users, and tobacco smokers.. Physiological reports, 2022.
- Ruedisueli I, Ma J, Nguyen R, Lakhani K, Gornbein J, Middlekauff HR. Optimizing ECG lead selection for detection of prolongation of ventricular repolarization as measured by the Tpeak-end interval.. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2022.
- Middlekauff HR, Cooper ZD, Strauss SB. Drugs of Misuse: Focus on Vascular Dysfunction.. The Canadian journal of cardiology, 2022.
- Kelesidis T, Zhang Y, Tran E, Sosa G, Middlekauff HR. Instigators of COVID-19 in Immune Cells Are Increased in Tobacco Cigarette Smokers and Electronic Cigarette Vapers Compared With Nonsmokers.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2022.
- Kelesidis T, Tran E, Nguyen R, Zhang Y, Sosa G, Middlekauff HR. Association of 1 Vaping Session With Cellular Oxidative Stress in Otherwise Healthy Young People With No History of Smoking or Vaping: A Randomized Clinical Crossover Trial.. JAMA pediatrics, 2021.
- Gupta R, Lin Y, Luna K, Logue A, Yoon AJ, Haptonstall KP, Moheimani R, Choroomi Y, Nguyen K, Tran E, Zhu Y, Faull KF, Kelesidis T, Gornbein J, Middlekauff HR, Araujo JA. Electronic and Tobacco Cigarettes Alter Polyunsaturated Fatty Acids and Oxidative Biomarkers.. Circulation research, 2021.
- Kelesidis T, Zhang Y, Tran E, Sosa G, Middlekauff HR. Increased Expression of Proatherogenic Proteins in Immune Cell Subtypes in Tobacco Cigarette Smokers But Not in Electronic Cigarette Vapers.. The Canadian journal of cardiology, 2021.
- Shahandeh N, Chowdhary H, Middlekauff HR. Vaping and cardiac disease.. Heart (British Cardiac Society), 2021.
- Kelesidis T, Zhang Y, Tran E, Sosa G, Middlekauff HR. Expression of Key Inflammatory Proteins Is Increased in Immune Cells From Tobacco Cigarette Smokers But Not Electronic Cigarette Vapers: Implications for Atherosclerosis.. Journal of the American Heart Association, 2020.
- Nayeri A, Middlekauff H. Vaping Instead of Cigarette Smoking: A Panacea or Just Another Form of Cardiovascular Risk?. The Canadian journal of cardiology, 2020.
- Middlekauff HR, William KJ, Su B, Haptonstall K, Araujo JA, Wu X, Kim J, Sallam T. Changes in lipid composition associated with electronic cigarette use.. Journal of translational medicine, 2020.
- Kelesidis T, Tran E, Arastoo S, Lakhani K, Heymans R, Gornbein J, Middlekauff HR. Elevated Cellular Oxidative Stress in Circulating Immune Cells in Otherwise Healthy Young People Who Use Electronic Cigarettes in a Cross-Sectional Single-Center Study: Implications for Future Cardiovascular Risk.. Journal of the American Heart Association, 2020.
- Haptonstall KP, Choroomi Y, Moheimani R, Nguyen K, Tran E, Lakhani K, Ruedisueli I, Gornbein J, Middlekauff HR. Differential effects of tobacco cigarettes and electronic cigarettes on endothelial function in healthy young people.. American journal of physiology. Heart and circulatory physiology, 2020.
- Middlekauff HR. Cardiovascular effects of electronic cigarettes.. Nature reviews. Cardiology, 2020.
- Arastoo S, Haptonstall KP, Choroomi Y, Moheimani R, Nguyen K, Tran E, Gornbein J, Middlekauff HR. Acute and chronic sympathomimetic effects of e-cigarette and tobacco cigarette smoking: role of nicotine and non-nicotine constituents.. American journal of physiology. Heart and circulatory physiology, 2020.
- Feng Z, Philipson D, Uzzell JP, Stein-Merlob A, Yang EH, Middlekauff HR, Lau RP, Fishbein GA, Bradfield JS, Ajijola OA. A Case of Ventricular Tachycardia Caused by a Rare Cardiac Mesenchymal Hamartoma.. JACC. Case reports, 2020.
- Gordon SS, Hollowed J, Hayase J, Macias C, Wang J, Middlekauff HR. Acquired Long QT Syndrome after Acute Myocardial Infarction: A Rare but Potentially Fatal Entity.. Texas Heart Institute journal, 2020.
- Garcia PD, Gornbein JA, Middlekauff HR. Cardiovascular autonomic effects of electronic cigarette use: a systematic review.. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2020.
- Ip M, Diamantakos E, Haptonstall K, Choroomi Y, Moheimani RS, Nguyen KH, Tran E, Gornbein J, Middlekauff HR. Tobacco and electronic cigarettes adversely impact ECG indexes of ventricular repolarization: implication for sudden death risk.. American journal of physiology. Heart and circulatory physiology, 2020.
- MacDonald A, Middlekauff HR. Electronic cigarettes and cardiovascular health: what do we know so far?. Vascular health and risk management, 2019.
- Middlekauff HR. Cardiovascular impact of electronic-cigarette use.. Trends in cardiovascular medicine, 2019.
- Middlekauff HR, Gornbein J. Association of Electronic Cigarette Use With Myocardial Infarction: Persistent Uncertainty.. American journal of preventive medicine, 2018.
- Park SH, Fonkoue IT, Li Y, DaCosta DR, Middlekauff HR, Park J. Augmented Cardiopulmonary Baroreflex Sensitivity in Intradialytic Hypertension.. Kidney international reports, 2018.
- Ip M, Middlekauff HR. Noncigarette Tobacco Products-Gateway or Diversion?. JAMA pediatrics, 2018.
- Middlekauff HR, Araujo JA. Increased Cardiovascular Risk Associated With E-Cigarette Use-Reply.. JAMA cardiology, 2017.
- Moheimani RS, Bhetraratana M, Peters KM, Yang BK, Yin F, Gornbein J, Araujo JA, Middlekauff HR. Sympathomimetic Effects of Acute E-Cigarette Use: Role of Nicotine and Non-Nicotine Constituents.. Journal of the American Heart Association, 2017.
- Boas Z, Gupta P, Moheimani RS, Bhetraratana M, Yin F, Peters KM, Gornbein J, Araujo JA, Czernin J, Middlekauff HR. Activation of the "Splenocardiac Axis" by electronic and tobacco cigarettes in otherwise healthy young adults.. Physiological reports, 2017.
- Moheimani RS, Bhetraratana M, Yin F, Peters KM, Gornbein J, Araujo JA, Middlekauff HR. Increased Cardiac Sympathetic Activity and Oxidative Stress in Habitual Electronic Cigarette Users: Implications for Cardiovascular Risk.. JAMA cardiology, 2017.
- Chen JJ, Wu PT, Middlekauff HR, Nguyen KL. Aerobic exercise in anthracycline-induced cardiotoxicity: a systematic review of current evidence and future directions.. American journal of physiology. Heart and circulatory physiology, 2016.
- Lobo DM, Trevizan PF, Toschi-Dias E, Oliveira PA, Piveta RB, Almeida DR, Mady C, Bocchi EA, Lorenzi-Filho G, Middlekauff HR, Negrão CE. Sleep-Disordered Breathing Exacerbates Muscle Vasoconstriction and Sympathetic Neural Activation in Patients with Systolic Heart Failure.. Circulation. Heart failure, 2016.
- Loewenstein DK, Middlekauff HR. Electronic Cigarette Device-Related Hazards:: A Call for Immediate FDA Regulation.. American journal of preventive medicine, 2016.
- Nobre TS, Antunes-Correa LM, Groehs RV, Alves MJ, Sarmento AO, Bacurau AV, Urias U, Alves GB, Rondon MU, Brum PC, Martinelli M, Middlekauff HR, Negrao CE. Exercise training improves neurovascular control and calcium cycling gene expression in patients with heart failure with cardiac resynchronization therapy.. American journal of physiology. Heart and circulatory physiology, 2016.
- Macey PM, Rieken NS, Kumar R, Ogren JA, Middlekauff HR, Wu P, Woo MA, Harper RM. Sex Differences in Insular Cortex Gyri Responses to the Valsalva Maneuver.. Frontiers in neurology, 2016.
- Middlekauff HR. COUNTERPOINT: Does the Risk of Electronic Cigarettes Exceed Potential Benefits? No.. Chest, 2015.
- Middlekauff HR. Rebuttal From Dr Middlekauff.. Chest, 2015.
- Santos MR, Sayegh AL, Groehs RV, Fonseca G, Trombetta IC, Barretto AC, Arap MA, Negrão CE, Middlekauff HR, Alves MJ. Testosterone deficiency increases hospital readmission and mortality rates in male patients with heart failure.. Arquivos brasileiros de cardiologia, 2015.
- Middlekauff HR. A mechanistic explanation for the minimal impact of renal denervation on 24-h ambulatory blood pressure in SIMPLICITY HTN-3.. Journal of the American College of Cardiology, 2015.
- Groehs RV, Toschi-Dias E, Antunes-Correa LM, Trevizan PF, Rondon MU, Oliveira P, Alves MJ, Almeida DR, Middlekauff HR, Negrão CE. Exercise training prevents the deterioration in the arterial baroreflex control of sympathetic nerve activity in chronic heart failure patients.. American journal of physiology. Heart and circulatory physiology, 2015.
- Negrao CE, Middlekauff HR, Gomes-Santos IL, Antunes-Correa LM. Effects of exercise training on neurovascular control and skeletal myopathy in systolic heart failure.. American journal of physiology. Heart and circulatory physiology, 2015.
- Ramanathan G, Araujo JA, Gornbein J, Yin F, Middlekauff HR. Cigarette smoking is associated with dose-dependent adverse effects on paraoxonase activity and fibrinogen in young women.. Inhalation toxicology, 2014.
- Park J, Middlekauff HR. Abnormal neurocirculatory control during exercise in humans with chronic renal failure.. Autonomic neuroscience : basic & clinical, 2014.
- Middlekauff HR, Park J, Moheimani RS. Adverse effects of cigarette and noncigarette smoke exposure on the autonomic nervous system: mechanisms and implications for cardiovascular risk.. Journal of the American College of Cardiology, 2014.
- DiFranco M, Quiñonez M, Shieh P, Fonarow GC, Cruz D, Deng MC, Vergara JL, Middlekauff HR. Action potential-evoked calcium release is impaired in single skeletal muscle fibers from heart failure patients.. PloS one, 2014.
- Antunes-Correa LM, Nobre TS, Groehs RV, Alves MJ, Fernandes T, Couto GK, Rondon MU, Oliveira P, Lima M, Mathias W, Brum PC, Mady C, Almeida DR, Rossoni LV, Oliveira EM, Middlekauff HR, Negrao CE. Molecular basis for the improvement in muscle metaboreflex and mechanoreflex control in exercise-trained humans with chronic heart failure.. American journal of physiology. Heart and circulatory physiology, 2014.
- Middlekauff HR, Park J, Agrawal H, Gornbein JA. Abnormal sympathetic nerve activity in women exposed to cigarette smoke: a potential mechanism to explain increased cardiac risk.. American journal of physiology. Heart and circulatory physiology, 2013.
- Middlekauff HR, Verity MA, Horwich TB, Fonarow GC, Hamilton MA, Shieh P. Intact skeletal muscle mitochondrial enzyme activity but diminished exercise capacity in advanced heart failure patients on optimal medical and device therapy.. Clinical research in cardiology : official journal of the German Cardiac Society, 2013.
- Park J, Quyyumi AA, Middlekauff HR. Exercise pressor response and arterial baroreflex unloading during exercise in chronic kidney disease.. Journal of applied physiology (Bethesda, Md. : 1985), 2012.
- Middlekauff HR, Vigna C, Verity MA, Fonarow GC, Horwich TB, Hamilton MA, Shieh P, Tupling AR. Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?. Journal of cardiac failure, 2012.
- Park J, Middlekauff HR, Campese VM. Abnormal sympathetic reactivity to the cold pressor test in overweight humans.. American journal of hypertension, 2012.
- Nazaré Nunes Alves MJ, Alves MJ, dos Santos MR, Nobre TS, Martinez DG, Martinez DG, Pereira Barretto AC, Brum PC, Rondon MU, Middlekauff HR, Negrão CE. Mechanisms of blunted muscle vasodilation during peripheral chemoreceptor stimulation in heart failure patients.. Hypertension (Dallas, Tex. : 1979), 2012.
- Middlekauff HR, Park J, Gornbein JA. Lack of effect of ovarian cycle and oral contraceptives on baroreceptor and nonbaroreceptor control of sympathetic nerve activity in healthy women.. American journal of physiology. Heart and circulatory physiology, 2012.
- Martinez DG, Nicolau JC, Lage RL, Toschi-Dias E, de Matos LD, Alves MJ, Trombetta IC, Dias da Silva VJ, Middlekauff HR, Negrão CE, Rondon MU. Effects of long-term exercise training on autonomic control in myocardial infarction patients.. Hypertension (Dallas, Tex. : 1979), 2011.
- Horwich TB, Middlekauff HR, Maclellan WR, Fonarow GC. Statins do not significantly affect muscle sympathetic nerve activity in humans with nonischemic heart failure: a double-blind placebo-controlled trial.. Journal of cardiac failure, 2011.
- Antunes-Correa LM, Kanamura BY, Melo RC, Nobre TS, Ueno LM, Franco FG, Roveda F, Braga AM, Rondon MU, Brum PC, Barretto AC, Middlekauff HR, Negrao CE. Exercise training improves neurovascular control and functional capacity in heart failure patients regardless of age.. European journal of preventive cardiology, 2011.
- Soares-Miranda L, Franco FG, Roveda F, Martinez DG, Rondon MU, Mota J, Brum PC, Antunes-Correa LM, Nobre TS, Barretto AC, Middlekauff HR, Negrao CE. Effects of exercise training on neurovascular responses during handgrip exercise in heart failure patients.. International journal of cardiology, 2010.
- Middlekauff HR. Making the case for skeletal myopathy as the major limitation of exercise capacity in heart failure.. Circulation. Heart failure, 2010.
- Antunes-Correa LM, Melo RC, Nobre TS, Ueno LM, Franco FG, Braga AM, Rondon MU, Brum PC, Barretto AC, Middlekauff HR, Negrao CE. Impact of gender on benefits of exercise training on sympathetic nerve activity and muscle blood flow in heart failure.. European journal of heart failure, 2010.
- Park J, Middlekauff HR. Altered pattern of sympathetic activity with the ovarian cycle in female smokers.. American journal of physiology. Heart and circulatory physiology, 2009.
- Ueno LM, Drager LF, Rodrigues AC, Rondon MU, Braga AM, Mathias W, Krieger EM, Barretto AC, Middlekauff HR, Lorenzi-Filho G, Negrão CE. Effects of exercise training in patients with chronic heart failure and sleep apnea.. Sleep, 2009.
- Park J, Campese VM, Nobakht N, Middlekauff HR. Differential distribution of muscle and skin sympathetic nerve activity in patients with end-stage renal disease.. Journal of applied physiology (Bethesda, Md. : 1985), 2008.
- Negrão CE, Santos AC, Rondon MU, Franco FG, Ianni B, Rochitte CE, Braga AM, Oliveira MT, Mady C, Barretto AC, Middlekauff HR. Muscle sympathetic nerve activity in patients with Chagas' disease.. International journal of cardiology, 2008.
- Park J, Campese VM, Middlekauff HR. Exercise pressor reflex in humans with end-stage renal disease.. American journal of physiology. Regulatory, integrative and comparative physiology, 2008.
- Barretto AC, Santos AC, Munhoz R, Rondon MU, Franco FG, Trombetta IC, Roveda F, de Matos LN, Braga AM, Middlekauff HR, Negrão CE. Increased muscle sympathetic nerve activity predicts mortality in heart failure patients.. International journal of cardiology, 2008.
- Horwich TB, Middlekauff HR. Potential autonomic nervous system effects of statins in heart failure.. Heart failure clinics, 2008.
- Middlekauff HR, Chiu J, Hamilton MA, Fonarow GC, Maclellan WR, Hage A, Moriguchi J, Patel J. Cyclooxygenase products sensitize muscle mechanoreceptors in humans with heart failure.. American journal of physiology. Heart and circulatory physiology, 2008.
- Negrao CE, Middlekauff HR. Adaptations in autonomic function during exercise training in heart failure.. Heart failure reviews, 2008.
- Negrão CE, Middlekauff HR. Exercise training in heart failure: reduction in angiotensin II, sympathetic nerve activity, and baroreflex control.. Journal of applied physiology (Bethesda, Md. : 1985), 2008.
- Alves MJ, Rondon MU, Santos AC, Dias RG, Barretto AC, Krieger EM, Middlekauff HR, Negrão CE. Sympathetic nerve activity restrains reflex vasodilatation in heart failure.. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2007.
- Fraga R, Franco FG, Roveda F, de Matos LN, Braga AM, Rondon MU, Rotta DR, Brum PC, Barretto AC, Middlekauff HR, Negrão CE. Exercise training reduces sympathetic nerve activity in heart failure patients treated with carvedilol.. European journal of heart failure, 2007.
- Di Vanna A, Braga AM, Laterza MC, Ueno LM, Rondon MU, Barretto AC, Middlekauff HR, Negrão CE. Blunted muscle vasodilatation during chemoreceptor stimulation in patients with heart failure.. American journal of physiology. Heart and circulatory physiology, 2007.
- Middlekauff HR, Sinoway LI. Increased mechanoreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure.. Journal of applied physiology (Bethesda, Md. : 1985), 2006.
- Rondon E, Brasileiro-Santos MS, Moreira ED, Rondon MU, Mattos KC, Coelho MA, Silva GJ, Brum PC, Fiorino P, Irigoyen MC, Krieger EM, Middlekauff HR, Negrão CE. Exercise training improves aortic depressor nerve sensitivity in rats with ischemia-induced heart failure.. American journal of physiology. Heart and circulatory physiology, 2006.
- de Mello Franco FG, Santos AC, Rondon MU, Trombetta IC, Strunz C, Braga AM, Middlekauff H, Negrão CE, Pereira Barretto AC. Effects of home-based exercise training on neurovascular control in patients with heart failure.. European journal of heart failure, 2006.
- Rolim NP, Mattos KC, Brum PC, Baldo MV, Middlekauff HR, Negrão CE. The decreased oxygen uptake during progressive exercise in ischemia-induced heart failure is due to reduced cardiac output rate.. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2006.
- Middlekauff HR. How does cardiac resynchronization therapy improve exercise capacity in chronic heart failure?. Journal of cardiac failure, 2005.
- Santos AC, Alves MJ, Rondon MU, Barretto AC, Middlekauff HR, Negrão CE. Sympathetic activation restrains endothelium-mediated muscle vasodilatation in heart failure patients.. American journal of physiology. Heart and circulatory physiology, 2005.
- Thomas MA, Chung HK, Middlekauff H. Localized two-dimensional 1H magnetic resonance exchange spectroscopy: a preliminary evaluation in human muscle.. Magnetic resonance in medicine, 2005.
- De Matos LD, Gardenghi G, Rondon MU, Soufen HN, Tirone AP, Barretto AC, Brum PC, Middlekauff HR, Negrão CE. Impact of 6 months of therapy with carvedilol on muscle sympathetic nerve activity in heart failure patients.. Journal of cardiac failure, 2004.
- Middlekauff HR, Chiu J. Cyclooxygenase products sensitize muscle mechanoreceptors in healthy humans.. American journal of physiology. Heart and circulatory physiology, 2004.
- Middlekauff HR, Chiu J, Hamilton MA, Fonarow GC, Maclellan WR, Hage A, Moriguchi J, Patel J. Muscle mechanoreceptor sensitivity in heart failure.. American journal of physiology. Heart and circulatory physiology, 2004.
- Middlekauff HR. Acupuncture in the treatment of heart failure.. Cardiology in review, 2004.
- Middlekauff HR, Shah JB, Yu JL, Hui K. Acupuncture effects on autonomic responses to cold pressor and handgrip exercise in healthy humans.. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2004.
- Tede NH, Shivkumar K, Perloff JK, Middlekauff HR, Fishbein MC, Child JS, Laks H. Signal-averaged electrocardiogram in Ebstein's anomaly.. The American journal of cardiology, 2004.
- Roveda F, Middlekauff HR, Rondon MU, Reis SF, Souza M, Nastari L, Barretto AC, Krieger EM, Negrão CE. The effects of exercise training on sympathetic neural activation in advanced heart failure: a randomized controlled trial.. Journal of the American College of Cardiology, 2003.
- Middlekauff HR, Hui K, Yu JL, Hamilton MA, Fonarow GC, Moriguchi J, Maclellan WR, Hage A. Acupuncture inhibits sympathetic activation during mental stress in advanced heart failure patients.. Journal of cardiac failure, 2002.
- Middlekauff HR, Yu JL, Hui K. Acupuncture effects on reflex responses to mental stress in humans.. American journal of physiology. Regulatory, integrative and comparative physiology, 2001.
- Middlekauff HR, Nitzsche EU, Hoh CK, Hamilton MA, Fonarow GC, Hage A, Moriguchi JD. Exaggerated muscle mechanoreflex control of reflex renal vasoconstriction in heart failure.. Journal of applied physiology (Bethesda, Md. : 1985), 2001.
- Middlekauff HR, Doering A, Weiss JN. Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons.. Circulation, 2001.
- Negrão CE, Rondon MU, Tinucci T, Alves MJ, Roveda F, Braga AM, Reis SF, Nastari L, Barretto AC, Krieger EM, Middlekauff HR. Abnormal neurovascular control during exercise is linked to heart failure severity.. American journal of physiology. Heart and circulatory physiology, 2001.
- Middlekauff HR, Nitzsche EU, Hoh CK, Hamilton MA, Fonarow GC, Hage A, Moriguchi JD. Exaggerated renal vasoconstriction during exercise in heart failure patients.. Circulation, 2000.
- Negrao CE, Hamilton MA, Fonarow GC, Hage A, Moriguchi JD, Middlekauff HR. Impaired endothelium-mediated vasodilation is not the principal cause of vasoconstriction in heart failure.. American journal of physiology. Heart and circulatory physiology, 2000.
- Wilkes MS, Middlekauff H, Hoffman JR. Heart failure: Part II.. The Western journal of medicine, 1999.
- Wilkes MS, Middlekauff H, Hoffman JR. Heart failure: Part I. First hospitalization and post-hospital care.. The Western journal of medicine, 1999.
- Middlekauff HR, Mark AL. The treatment of heart failure: the role of neurohumoral activation.. Internal medicine (Tokyo, Japan), 1998.
- Middlekauff HR, Nguyen AH, Negrao CE, Nitzsche EU, Hoh CK, Natterson BA, Hamilton MA, Fonarow GC, Hage A, Moriguchi JD. Impact of acute mental stress on sympathetic nerve activity and regional blood flow in advanced heart failure: implications for 'triggering' adverse cardiac events.. Circulation, 1997.
- Middlekauff HR. Mechanisms and implications of autonomic nervous system dysfunction in heart failure.. Current opinion in cardiology, 1997.
- Middlekauff HR, Nitzsche EU, Nguyen AH, Hoh CK, Gibbs GG. Modulation of renal cortical blood flow during static exercise in humans.. Circulation research, 1997.
- Stevenson WG, Stevenson LW, Middlekauff HR, Fonarow GC, Hamilton MA, Woo MA, Saxon LA, Natterson PD, Steimle A, Walden JA, Tillisch JH. Improving survival for patients with atrial fibrillation and advanced heart failure.. Journal of the American College of Cardiology, 1996.
- Nguyen AH, Garfinkel A, Walter DO, Hamilton MA, Fonarow GC, Moriguchi JD, Hage A, Weiss JN, Middlekauff HR. Dynamics of muscle sympathetic nerve activity in advanced heart failure patients.. The American journal of physiology, 1996.
- Stevenson WG, Stevenson LW, Middlekauff HR, Fonarow GC, Hamilton MA, Woo MA, Saxon LA, Natterson PD, Steimle A, Walden JA. Improving survival for patients with advanced heart failure: a study of 737 consecutive patients.. Journal of the American College of Cardiology, 1995.
- Middlekauff HR, Stevenson WG, Saxon LA, Stevenson LW. Amiodarone and torsades de pointes in patients with advanced heart failure.. The American journal of cardiology, 1995.
- Middlekauff HR, Nitzsche EU, Hamilton MA, Schelbert HR, Fonarow GC, Moriguchi JD, Hage A, Saleh S, Gibbs GG. Evidence for preserved cardiopulmonary baroreflex control of renal cortical blood flow in humans with advanced heart failure. A positron emission tomography study.. Circulation, 1995.
- Stevenson WG, Sager PT, Natterson PD, Saxon LA, Middlekauff HR, Wiener I. Relation of pace mapping QRS configuration and conduction delay to ventricular tachycardia reentry circuits in human infarct scars.. Journal of the American College of Cardiology, 1995.
- Chun SH, Sager PT, Stevenson WG, Nademanee K, Middlekauff HR, Singh BN. Long-term efficacy of amiodarone for the maintenance of normal sinus rhythm in patients with refractory atrial fibrillation or flutter.. The American journal of cardiology, 1995.
- Middlekauff HR, Sontz EM. Morning sympathetic nerve activity is not increased in humans. Implications for mechanisms underlying the circadian pattern of cardiac risk.. Circulation, 1995.
- Middlekauff HR, Stevenson WG, Gornbein JA. Antiarrhythmic prophylaxis vs warfarin anticoagulation to prevent thromboembolic events among patients with atrial fibrillation. A decision analysis.. Archives of internal medicine, 1995.
- Natterson PD, Stevenson WG, Saxon LA, Middlekauff HR, Stevenson LW. Risk of arterial embolization in 224 patients awaiting cardiac transplantation.. American heart journal, 1995.
- Middlekauff HR, Hamilton MA, Stevenson LW, Mark AL. Independent control of skin and muscle sympathetic nerve activity in patients with heart failure.. Circulation, 1994.
- Woo MA, Stevenson WG, Moser DK, Middlekauff HR. Complex heart rate variability and serum norepinephrine levels in patients with advanced heart failure.. Journal of the American College of Cardiology, 1994.
- Stevenson WG, Stevenson LW, Middlekauff HR, Saxon LA. Sudden death prevention in patients with advanced ventricular dysfunction.. Circulation, 1993.
- Middlekauff HR, Wiener I, Stevenson WG. Low-dose amiodarone for atrial fibrillation.. The American journal of cardiology, 1993.
- Saxon LA, Stevenson WG, Fonarow GC, Middlekauff HR, Yeatman LA, Sherman CT, Child JS. Transesophageal echocardiography during radiofrequency catheter ablation of ventricular tachycardia.. The American journal of cardiology, 1993.
- Saxon LA, Stevenson WG, Middlekauff HR, Fonarow G, Woo M, Moser D, Stevenson LW. Predicting death from progressive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.. The American journal of cardiology, 1993.
- Saxon LA, Stevenson WG, Middlekauff HR, Stevenson LW. Increased risk of progressive hemodynamic deterioration in advanced heart failure patients requiring permanent pacemakers.. American heart journal, 1993.
- Middlekauff HR, Stevenson WG, Stevenson LW, Saxon LA. Syncope in advanced heart failure: high risk of sudden death regardless of origin of syncope.. Journal of the American College of Cardiology, 1993.
- Chelimsky-Fallick C, Middlekauff HR, Stevenson WG, Kobashigawa J, Saxon LA, Moriguchi J, Brownfield ED, Hamilton MA, Drinkwater D, Laks H. Amiodarone therapy does not compromise subsequent heart transplantation.. Journal of the American College of Cardiology, 1992.
- Stevenson WG, Middlekauff HR, Stevenson LW, Saxon LA, Woo MA, Moser D. Significance of aborted cardiac arrest and sustained ventricular tachycardia in patients referred for treatment therapy of advanced heart failure.. American heart journal, 1992.
- Middlekauff HR, Stevenson WG, Tillisch JH. Prevention of sudden death in survivors of myocardial infarction: a decision analysis approach.. American heart journal, 1992.
- Middlekauff HR, Stevenson WG, Stevenson LW. Prognostic significance of atrial fibrillation in advanced heart failure. A study of 390 patients.. Circulation, 1991.
- Middlekauff HR, Stevenson WG, Woo MA, Moser DK, Stevenson LW. Comparison of frequency of late potentials in idiopathic dilated cardiomyopathy and ischemic cardiomyopathy with advanced congestive heart failure and their usefulness in predicting sudden death.. The American journal of cardiology, 1990.