
Janet S Sinsheimer
Professor, Human Genetics, University of California Los Angeles
Professor, Computational Medicine, University of California Los Angeles
5-357C Gonda / 5213 LSB
Los Angeles, CA 90095 Gonda Center
Los Angeles, CA 90095
Affiliations
Member, Bioinformatics GPB Home Area, CTSI, Genetics & Genomics GPB Home Area, JCCC Healthy and At-Risk Populations Program Area, JCCC Molecular Epidemiology Program Area
Research Interests
Dr. Sinsheimer’s research is focused on developing mathematical models of evolution and genetics. Her research program involves the development and application of statistical methodology for mapping complex trait and disease genes. Most recently, her group have been working on statistical methods for detecting disease genes acting through maternal-fetal genotype incompatibility and models to disentangle maternal genetic effects from environment. She has also developed methods for realistic inference of evolutionary relationships in a Bayesian context and applied these methods to HIV evolution. Her research in HIV evolution has been geared towards understanding the mechanisms by which HIV evades the immune system.
Biography
Janet Sinsheimer is a Professor in the Departments of Human Genetics, Computational Medicine and Biostatistics at UCLA. She has a PhD in Biomathematics (UCLA), an MA in Biochemistry (Brandeis) and an ScB in Chemistry (Brown U). Dr. Sinsheimer’s research is focused on developing mathematical models for the analysis of genomic and genetic data. She has also developed methods for realistic inference of evolutionary relationships. Most recently, her group has been working on novel statistical methods for detecting disease and trait genes via a variance component paradigm and on methods of rapid inference with big genetic and genomic data sets.
Publications
A selected list of publications:
- Palmer Christina G S, Boudreault Patrick, Baldwin Erin E, Fox Michelle, Deignan Joshua L, Kobayashi Yoko, Sininger Yvonne, Grody Wayne, Sinsheimer Janet S Deaf genetic testing and psychological well-being in deaf adults Journal of genetic counseling, 2013; 22(4): 492-507.
- Lange Kenneth, Papp Jeanette C, Sinsheimer Janet S, Sripracha Ram, Zhou Hua, Sobel Eric M Mendel: the Swiss army knife of genetic analysis programs Bioinformatics (Oxford, England), 2013; 29(12): 1568-70.
- Lee Pei-Chen, Rhodes Shannon L, Sinsheimer Janet S, Bronstein Jeff, Ritz Beate Functional paraoxonase 1 variants modify the risk of Parkinson’s disease due to organophosphate exposure Environment international, 2013; 56(12): 42-7.
- Weissglas-Volkov Daphna, Aguilar-Salinas Carlos A, Nikkola Elina, Deere Kerry A, Cruz-Bautista Ivette, Arellano-Campos Olimpia, Muñoz-Hernandez Linda Liliana, Gomez-Munguia Lizeth, Ordoñez-Sánchez Maria Luisa, Reddy Prasad M V Linga, Lusis Aldons J, Matikainen Niina, Taskinen Marja-Riitta, Riba Laura, Cantor Rita M, Sinsheimer Janet S, Tusie-Luna Teresa, Pajukanta Päivi Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci Journal of medical genetics, 2013; 50(5): 298-308.
- Cybis Gabriela B, Sinsheimer Janet S, Lemey Philippe, Suchard Marc A Graph hierarchies for phylogeography Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013; 368(1614): 20120206.
- Clark Michelle M, Blangero John, Dyer Thomas D, Sobel Eric M, Sinsheimer Janet S The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions Annals of human genetics, 2016; 80(1): 63-80.
- Lange Kenneth, Papp Jeanette C, Sinsheimer Janet S, Sobel Eric M Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data Annual review of statistics and its application, 2014; 1(1): 279-300.
- Clark Michelle M, Chazara Olympe, Sobel Eric M, Gjessing Håkon K, Magnus Per, Moffett Ashley, Sinsheimer Janet S Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes Human heredity, 2016; 81(4): 181-193.
- Cybis Gabriela B, Sinsheimer Janet S, Bedford Trevor, Rambaut Andrew, Lemey Philippe, Suchard Marc A Bayesian nonparametric clustering in phylogenetics: modeling antigenic evolution in influenza Statistics in medicine, 2018; 37(2): 195-206.
- Lake James A, Larsen Joseph, Sarna Brooke, de la Haba Rafael R, Pu Yiyi, Koo HyunMin, Zhao Jun, Sinsheimer Janet S Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria Genome biology and evolution, 2015; 7(12): 3434-42.
- Chuang Yu-Hsuan, Lill Christina M, Lee Pei-Chen, Hansen Johnni, Lassen Christina F, Bertram Lars, Greene Naomi, Sinsheimer Janet S, Ritz Beate Gene-Environment Interaction in Parkinson’s Disease: Coffee, ADORA2A, and CYP1A2 Neuroepidemiology, 2016; 47(3-4): 192-200.
- Boudreault Patrick, Wolfson Alicia, Berman Barbara, Venne Vickie L, Sinsheimer Janet S, Palmer Christina Bilingual Cancer Genetic Education Modules for the Deaf Community: Development and Evaluation of the Online Video Material Journal of genetic counseling, 2017; 37(2): 195-206.
- Narayan Shilpa, Sinsheimer Janet S, Paul Kimberly C, Liew Zeyan, Cockburn Myles, Bronstein Jeff M, Ritz Beate Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson’s disease Environmental research, 2015; 143(Pt A): 98-106.
- Kusters Cynthia D J, Paul Kimberly C, Guella Ilaria, Bronstein Jeff M, Sinsheimer Janet S, Farrer Matt J, Ritz Beate R Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson’s disease Parkinsonism & related disorders, 2017; 37(2): 195-206.
- Gilbert Princess S, Chang Jonathan, Pan Calvin, Sobel Eric M, Sinsheimer Janet S, Faircloth Brant C, Alfaro Michael E Genome-wide ultraconserved elements exhibit higher phylogenetic informativeness than traditional gene markers in percomorph fishes Molecular phylogenetics and evolution, 2015; 92(Pt A): 140-6.
- Paul Kimberly C, Sinsheimer Janet S, Cockburn Myles, Bronstein Jeff M, Bordelon Yvette, Ritz Beate Organophosphate pesticides and PON1 L55M in Parkinson’s disease progression Environment international, 2017; 107(2): 75-81.
- Cybis Gabriela B, Sinsheimer Janet S, Bedford Trevor, Mather Alison E, Lemey Philippe, Suchard Marc A ASSESSING PHENOTYPIC CORRELATION THROUGH THE MULTIVARIATE PHYLOGENETIC LATENT LIABILITY MODEL The annals of applied statistics, 2015; 9(2): 969-991.
- vonHoldt Bridgett M, Shuldiner Emily, Koch Ilana Janowitz, Kartzinel Rebecca Y, Hogan Andrew, Brubaker Lauren, Wanser Shelby, Stahler Daniel, Wynne Clive D L, Ostrander Elaine A, Sinsheimer Janet S, Udell Monique A R Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs Science advances, 2017; 3(7): e1700398.
- Huertas-Vazquez Adriana, Nelson Christopher P, Sinsheimer Janet S, Reinier Kyndaron, Uy-Evanado Audrey, Teodorescu Carmen, Ayala Jo, Hall Alistair S, Gunson Karen, Jui Jonathan, Samani Nilesh J, Chugh Sumeet S Cumulative effects of common genetic variants on risk of sudden cardiac death International journal of cardiology. Heart & vasculature, 2015; 7(2): 88-91.
- Lorenzo Bermejo Justo, Boekstegers Felix, González Silos Rosa, Marcelain Katherine, Baez Benavides Pablo, Barahona Ponce Carol, Müller Bettina, Ferreccio Catterina, Koshiol Jill, Fischer Christine, Peil Barbara, Sinsheimer Janet, Fuentes Guajardo Macarena, Barajas Olga, Gonzalez-Jose Rolando, Bedoya Gabriel, Cátira Bortolini Maria, Canizales-Quinteros Samuel, Gallo Carla, Ruiz Linares Andres, Rothhammer Francisco Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile PLoS genetics, 2017; 13(5): e1006756.
- Gatto Nicole M, Sinsheimer Janet S, Cockburn Myles, Escobedo Loraine A, Bordelon Yvette, Ritz Beate Vitamin D receptor gene polymorphisms and Parkinson’s disease in a population with high ultraviolet radiation exposure Journal of the neurological sciences, 2015; 352(1-2): 88-93.
- Crandall Carolyn J, Manson JoAnn E, Hohensee Chancellor, Horvath Steve, Wactawski-Wende Jean, LeBlanc Erin S, Vitolins Mara Z, Nassir Rami, Sinsheimer Janet S Association of genetic variation in the tachykinin receptor 3 locus with hot flashes and night sweats in the Women’s Health Initiative Study Menopause (New York, N.Y.), 2017; 24(3): 252-261.
- Rickabaugh Tammy M, Baxter Ruth M, Sehl Mary, Sinsheimer Janet S, Hultin Patricia M, Hultin Lance E, Quach Austin, Martínez-Maza Otoniel, Horvath Steve, Vilain Eric, Jamieson Beth D Acceleration of age-associated methylation patterns in HIV-1-infected adults PloS one, 2015; 10(3): e0119201.
- Han Eunjung, Sinsheimer Janet S, Novembre John Fast and accurate site frequency spectrum estimation from low coverage sequence data Bioinformatics (Oxford, England), 2015; 31(5): 720-7.
- Palmer Christina G S, Boudreault Patrick, Berman Barbara A, Wolfson Alicia, Duarte Lionel, Venne Vickie L, Sinsheimer Janet S Bilingual approach to online cancer genetics education for Deaf American Sign Language users produces greater knowledge and confidence than English text only: A randomized study Disability and health journal, 2017; 10(1): 23-32.
- Gatto Nicole M, Paul Kimberly C, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette, Rausch Rebecca, Ritz Beate Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson’s disease Journal of the neurological sciences, 2016; 370(1): 100-106.
- Palmer Christina G S, Boudreault Patrick, Baldwin Erin E, Sinsheimer Janet S Impact of genetic counseling and Connexin-26 and Connexin-30 testing on deaf identity and comprehension of genetic test results in a sample of deaf adults: a prospective, longitudinal study PloS one, 2014; 9(11): e111512.
- Lee Pei-Chen, Raaschou-Nielsen Ole, Lill Christina M, Bertram Lars, Sinsheimer Janet S, Hansen Johnni, Ritz Beate Gene-environment interactions linking air pollution and inflammation in Parkinson’s disease Environmental research, 2016; 151(1): 713-720.
- Arboleda Valerie A, Fleming Alice, Barseghyan Hayk, Délot Emmanuèle, Sinsheimer Janet S, Vilain Eric Regulation of sex determination in mice by a non-coding genomic region Genetics, 2014; 197(3): 885-97.
- Ngun Tuck C, Ghahramani Negar M, Creek Michelle M, Williams-Burris Shayna M, Barseghyan Hayk, Itoh Yuichiro, Sánchez Francisco J, McClusky Rebecca, Sinsheimer Janet S, Arnold Arthur P, Vilain Eric Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome Archives of sexual behavior, 2014; 43(6): 1043-57.
- Levine Andrew J, Soontornniyomkij Virawudh, Achim Cristian L, Masliah Eliezer, Gelman Benjamin B, Sinsheimer Janet S, Singer Elyse J, Moore David J Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV Journal of neurovirology, 2016; 22(4): 431-41.
- Anastasopoulos Eleftherios, Coleman Anne L, Wilson M Roy, Sinsheimer Janet S, Yu Fei, Katafigiotis Sokratis, Founti Panayiota, Salonikiou Angeliki, Pappas Theofanis, Koskosas Archimidis, Katopodi Theodora, Lambropoulos Alexandros, Topouzis Fotis Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study Investigative ophthalmology & visual science, 2014; 55(7): 4238-43.
- Paul Kimberly C, Sinsheimer Janet S, Rhodes Shannon L, Cockburn Myles, Bronstein Jeff, Ritz Beate Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson’s Disease, California (USA) Environmental health perspectives, 2016; 124(5): 570-7.
- Ko Arthur, Cantor Rita M, Weissglas-Volkov Daphna, Nikkola Elina, Reddy Prasad M V Linga, Sinsheimer Janet S, Pasaniuc Bogdan, Brown Robert, Alvarez Marcus, Rodriguez Alejandra, Rodriguez-Guillen Rosario, Bautista Ivette C, Arellano-Campos Olimpia, Muñoz-Hernández Linda L, Salomaa Veikko, Kaprio Jaakko, Jula Antti, Jauhiainen Matti, Heliövaara Markku, Raitakari Olli, Lehtimäki Terho, Eriksson Johan G, Perola Markus, Lohmueller Kirk E, Matikainen Niina, Taskinen Marja-Riitta, Rodriguez-Torres Maribel, Riba Laura, Tusie-Luna Teresa, Aguilar-Salinas Carlos A, Pajukanta Päivi Amerindian-specific regions under positive selection harbour new lipid variants in Latinos Nature communications, 2014; 5(7): 3983.
- Paul Kimberly C, Rausch Rebecca, Creek Michelle M, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette, Ritz Beate APOE, MAPT, and COMT and Parkinson’s Disease Susceptibility and Cognitive Symptom Progression Journal of Parkinson’s disease, 2016; 6(2): 349-59.
- Levine Andrew J, Reynolds Sandra, Cox Christopher, Miller Eric N, Sinsheimer Janet S, Becker James T, Martin Eileen, Sacktor Ned, Sacktor Ned The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning Journal of neurovirology, 2014; 20(3): 243-57.
- Janowitz Koch Ilana, Clark Michelle M, Thompson Michael J, Deere-Machemer Kerry A, Wang Jun, Duarte Lionel, Gnanadesikan Gitanjali E, McCoy Eskender L, Rubbi Liudmilla, Stahler Daniel R, Pellegrini Matteo, Ostrander Elaine A, Wayne Robert K, Sinsheimer Janet S, vonHoldt Bridgett M The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves Molecular ecology, 2016; 25(8): 1838-55.
- Han Eunjung, Sinsheimer Janet S, Novembre John Characterizing bias in population genetic inferences from low-coverage sequencing data Molecular biology and evolution, 2014; 31(3): 723-35.
- Lake James A, Larsen Joseph, Sarna Brooke, de la Haba Rafael R, Pu Yiyi, Koo HyunMin, Zhao Jun, Sinsheimer Janet S Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria Genome biology and evolution, 2016; 8(3): 578.
- Stutz Timothy C, Sinsheimer Janet S, Sehl Mary, Xu Jason Computational tools for assessing gene therapy under branching process models of mutation Bulletin of mathematical biology, 2021; 84(1): 15.
- Kusters Cynthia D J, Paul Kimberly C, Duarte Folle Aline, Keener Adrienne M, Bronstein Jeff M, Bertram Lars, Hansen Johnni, Horvath Steve, Sinsheimer Janet S, Lill Christina M, Ritz Beate R Increased Menopausal Age Reduces the Risk of Parkinson’s Disease: A Mendelian Randomization Approach Movement disorders : official journal of the Movement Disorder Society, 2021; 36(10): 2264-2272.
- Pan David Z, Garske Kristina M, Alvarez Marcus, Bhagat Yash V, Boocock James, Nikkola Elina, Miao Zong, Raulerson Chelsea K, Cantor Rita M, Civelek Mete, Glastonbury Craig A, Small Kerrin S, Boehnke Michael, Lusis Aldons J, Sinsheimer Janet S, Mohlke Karen L, Laakso Markku, Pajukanta Päivi, Ko Arthur Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS Nature communications, 2018; 9(1): 1512.
- Kusters Cynthia D J, Paul Kimberly C, Duarte Folle Aline, Keener Adrienne M, Bronstein Jeff M, Dobricic Valerija, Tysnes Ole-Bjørn, Bertram Lars, Alves Guido, Sinsheimer Janet S, Lill Christina M, Maple-Grødem Jodi, Ritz Beate R Genetic risk scores and hallucinations in patients with Parkinson disease Neurology. Genetics, 2020; 6(5): e492.
- Bolanos Rachel, Martinez-Maza Otoniel, Zhang Zuo-Feng, Hussain Shehnaz, Sehl Mary, Sinsheimer Janet S, D’Souza Gypsyarn, Jenkins Frank, Wolinsky Steven, Detels Roger Decreased levels of the serum inflammatory biomarkers, sGP130, IL-6, sCRP and BAFF, are associated with increased likelihood of AIDS related Kaposi’s sarcoma in men who have sex with men Cancer research frontiers, 2018; 4(1): 45-59.
- Chu Benjamin B, Keys Kevin L, German Christopher A, Zhou Hua, Zhou Jin J, Sobel Eric M, Sinsheimer Janet S, Lange Kenneth Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity GigaScience, 2020; 9(6): e492.
- Flores Yvonne N, Amoon Aryana T, Su Baolong, Velazquez-Cruz Rafael, Ramírez-Palacios Paula, Salmerón Jorge, Rivera-Paredez Berenice, Sinsheimer Janet S, Lusis Aldons J, Huertas-Vazquez Adriana, Saab Sammy, Glenn Beth A, May Folasade P, Williams Kevin J, Bastani Roshan, Bensinger Steven J Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico Lipids in health and disease, 2021; 20(1): 136.
- Fejzo Marlena Schoenberg, Myhre Ronny, Colodro-Conde Lucía, MacGibbon Kimber W, Sinsheimer Janet S, Reddy M V Prasad Linga, Pajukanta Päivi, Nyholt Dale R, Wright Margaret J, Martin Nicholas G, Engel Stephanie M, Medland Sarah E, Magnus Per, Mullin Patrick M Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2) Molecular and cellular endocrinology, 2017; 439(1): 308-316.
- German Christopher A, Sinsheimer Janet S, Klimentidis Yann C, Zhou Hua, Zhou Jin J Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale Genetic epidemiology, 2020; 44(3): 248-260.
- vonHoldt Bridgett M, DeCandia Alexandra L, Heppenheimer Elizabeth, Janowitz-Koch Ilana, Shi Ruoyao, Zhou Hua, German Christopher A, Brzeski Kristin E, Cassidy Kira A, Stahler Daniel R, Sinsheimer Janet S Heritability of interpack aggression in a wild pedigreed population of North American grey wolves Molecular ecology, 2020; 29(10): 1764-1775.
- Chang Chih-Chiang, Huang Zi-Yu, Shih Shu-Fu, Luo Yuan, Ko Arthur, Cui Qingyu, Sumner Jennifer, Cavallero Susana, Das Swarna, Gao Wei, Sinsheimer Janet, Bui Alex, Jacobs Jonathan P, Pajukanta Päivi, Wu Holden, Tai Yu-Chong, Li Zhaoping, Hsiai Tzung K Electrical impedance tomography for non-invasive identification of fatty liver infiltrate in overweight individuals Scientific reports, 2021; 11(1): 19859.
- Rhodes Shannon L, Buchanan Daniel D, Ahmed Ismaïl, Taylor Kent D, Loriot Marie-Anne, Sinsheimer Janet S, Bronstein Jeff M, Elbaz Alexis, Mellick George D, Rotter Jerome I, Ritz Beate Pooled analysis of iron-related genes in Parkinson’s disease: association with transferrin Neurobiology of disease, 2014; 62(1): 172-8.
- Lee Hane, Huang Alden Y, Wang Lee-Kai, Yoon Amanda J, Renteria Genecee, Eskin Ascia, Signer Rebecca H, Dorrani Naghmeh, Nieves-Rodriguez Shirley, Wan Jijun, Douine Emilie D, Woods Jeremy D, Dell’Angelica Esteban C, Fogel Brent L, Martin Martin G, Butte Manish J, Parker Neil H, Wang Richard T, Shieh Perry B, Wong Derek A, Gallant Natalie, Singh Kathryn E, Tavyev Asher Y Jane, Sinsheimer Janet S, Krakow Deborah, Loo Sandra K, Allard Patrick, Papp Jeanette C, Papp Jeanette C, Palmer Christina G S, Martinez-Agosto Julian A, Nelson Stanley F Diagnostic utility of transcriptome sequencing for rare Mendelian diseases Genetics in medicine : official journal of the American College of Medical Genetics, 2020; 22(3): 490-499.
- Kobayashi Yoko, Boudreault Patrick, Hill Karin, Sinsheimer Janet S, Palmer Christina G S Using a social marketing framework to evaluate recruitment of a prospective study of genetic counseling and testing for the deaf community BMC medical research methodology, 2013; 13(1): 145.
- Zhou Hua, Sinsheimer Janet S, Bates Douglas M, Chu Benjamin B, German Christopher A, Ji Sarah S, Keys Kevin L, Kim Juhyun, Ko Seyoon, Mosher Gordon D, Papp Jeanette C, Sobel Eric M, Zhai Jing, Zhou Jin J, Lange Kenneth OPENMENDEL: a cooperative programming project for statistical genetics Human genetics, 2020; 139(1): 61-71.
- Pan David Z, Miao Zong, Comenho Caroline, Rajkumar Sandhya, Koka Amogha, Lee Seung Hyuk T, Alvarez Marcus, Kaminska Dorota, Ko Arthur, Sinsheimer Janet S, Mohlke Karen L, Mancuso Nicholas, Muñoz-Hernandez Linda Liliana, Herrera-Hernandez Miguel, Tusié-Luna Maria Teresa, Aguilar-Salinas Carlos, Pietiläinen Kirsi H, Pihlajamäki Jussi, Laakso Markku, Garske Kristina M, Pajukanta Päivi Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes Genome medicine, 2021; 13(1): 123.
- Soontornniyomkij Virawudh, Moore David J, Gouaux Ben, Soontornniyomkij Benchawanna, Sinsheimer Janet S, Levine Andrew J Associations of regional amyloid-β plaque and phospho-tau pathology with biological factors and neuropsychological functioning among HIV-infected adults Journal of neurovirology, 2019; 25(6): 741-753.
- Chu Benjamin B, Sobel Eric M, Wasiolek Rory, Ko Seyoon, Sinsheimer Janet S, Zhou Hua, Lange Kenneth A fast Data-Driven method for genotype imputation, phasing, and local ancestry inference: MendelImpute.jl Bioinformatics (Oxford, England), 2021; 13(1): 123.
- Shih I-Fan, Haan Mary N, Paul Kimberly C, Yu Yu, Sinsheimer Janet S, Ritz Beate The Roles of Physical Activity and Inflammation in Mortality, Cognition, and Depressive Symptoms Among Older Mexican Americans American journal of epidemiology, 2019; 188(11): 1944-1952.
- German Christopher A, Sinsheimer Janet S, Zhou Jin, Zhou Hua WiSER: Robust and scalable estimation and inference of within-subject variances from intensive longitudinal data Biometrics, 2021; 13(1): 123.
- Garske Kristina M, Pan David Z, Miao Zong, Bhagat Yash V, Comenho Caroline, Robles Christopher R, Benhammou Jihane N, Alvarez Marcus, Ko Arthur, Ye Chun Jimmie, Pisegna Joseph R, Mohlke Karen L, Sinsheimer Janet S, Laakso Markku, Pajukanta Päivi Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans Nature metabolism, 2019; 1(6): 630-642.
- Landeros Alfonso, Ji Xiang, Lange Kenneth, Stutz Timothy C, Xu Jason, Sehl Mary E, Sinsheimer Janet S An examination of school reopening strategies during the SARS-CoV-2 pandemic PloS one, 2021; 16(5): e0251242.
- Chuang Yu-Hsuan, Paul Kimberly C, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette M, Ritz Beate Genetic variants in nicotinic receptors and smoking cessation in Parkinson’s disease Parkinsonism & related disorders, 2019; 62(6): 57-61.
- Ji Sarah S, German Christopher A, Lange Kenneth, Sinsheimer Janet S, Zhou Hua, Zhou Jin, Sobel Eric M Modern simulation utilities for genetic analysis BMC bioinformatics, 2021; 22(1): 228.
- Landeros Alfonso, Stutz Timothy, Keys Kevin L, Alekseyenko Alexander, Sinsheimer Janet S, Lange Kenneth, Sehl Mary E BioSimulator.jl: Stochastic simulation in Julia Computer methods and programs in biomedicine, 2018; 167(6): 23-35.
- Studwell Courtney M, Kelley Emily G, Kelley Emily G, Sinsheimer Janet S, Palmer Christina G S, LeBlanc Kimberly Family genetic result communication in rare and undiagnosed disease communities: Understanding the practice Journal of genetic counseling, 2021; 30(2): 439-447.
- Lin Liang-Yu, Chun Chang Sunny, O’Hearn Jim, Hui Simon T, Seldin Marcus, Gupta Pritha, Bondar Galyna, Deng Mario, Jauhiainen Raimo, Kuusisto Johanna, Laakso Markku, Sinsheimer Janet S, Deb Arjun, Rau Christoph, Ren Shuxun, Wang Yibin, Lusis Aldons J, Wang Jessica J, Huertas-Vazquez Adriana Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans G3 (Bethesda, Md.), 2018; 8(11): 3499-3506.
- Stutz Timothy C, Landeros Alfonso, Xu Jason, Sinsheimer Janet S, Sehl Mary, Lange Kenneth Stochastic simulation algorithms for Interacting Particle Systems PloS one, 2021; 16(3): e0247046.
- Gilbert Princess S, Wu Jing, Simon Margaret W, Sinsheimer Janet S, Alfaro Michael E Filtering nucleotide sites by phylogenetic signal to noise ratio increases confidence in the Neoaves phylogeny generated from ultraconserved elements Molecular phylogenetics and evolution, 2018; 126(5): 116-128.
- Palmer Christina G S, McConkie-Rosell Allyn, Holm Ingrid A, LeBlanc Kimberly, Sinsheimer Janet S, Briere Lauren C, Dorrani Naghmeh, Herzog Matthew R, Lincoln Sharyn, Schoch Kelly, Spillmann Rebecca C, Brokamp Elly, Brokamp Elly Understanding Adult Participant and Parent Empowerment Prior to Evaluation in the Undiagnosed Diseases Network Journal of genetic counseling, 2018; 27(5): 1087-1101.
- Pan David Z, Garske Kristina M, Alvarez Marcus, Bhagat Yash V, Boocock James, Nikkola Elina, Miao Zong, Raulerson Chelsea K, Cantor Rita M, Civelek Mete, Glastonbury Craig A, Small Kerrin S, Boehnke Michael, Lusis Aldons J, Sinsheimer Janet S, Mohlke Karen L, Laakso Markku, Pajukanta Päivi, Ko Arthur Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS Nature communications, 2018; 9(1): 3472.
- Crandall Carolyn J, Diamant Allison L, Maglione Margaret, Thurston Rebecca C, Sinsheimer Janet Genetic Variation and Hot Flashes: A Systematic Review The Journal of clinical endocrinology and metabolism, 2020; 105(12): e0247046.
- Lake James A, Larsen Joseph, Tran Dan Thy, Sinsheimer Janet S Uncovering the Genomic Origins of Life Genome biology and evolution, 2018; 10(7): 1705-1714.
- Hung Tony K W, Dong Tien S, Chen Zixi, Elashoff David, Sinsheimer Janet S, Jacobs Jonathan P, Lagishetty Venu, Vora Priten, Stains Jean, Mayer Emeran A, Gupta Arpana Understanding the Heterogeneity of Obesity and the Relationship to the Brain-Gut Axis Nutrients, 2020; 12(12): e0247046.
- Paul Kimberly C, Sinsheimer Janet S, Cockburn Myles, Bronstein Jeff M, Bordelon Yvette, Ritz Beate NFE2L2, PPARGC1α, and pesticides and Parkinson’s disease risk and progression Mechanisms of ageing and development, 2018; 173(7): 1-8.
- vonHoldt Bridgett M, Ji Sarah S, Aardema Matthew L, Stahler Daniel R, Udell Monique A R, Sinsheimer Janet S Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome Genome biology and evolution, 2018; 10(6): 1546-1553.
- Levine Andrew J, Soontornniyomkij Virawudh, Masliah Eliezer, Sinsheimer Janet S, Ji Sarah S, Horvath Steve, Singer Elyse J, Kallianpur Asha, Moore David J A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders Journal of neurovirology, 2020; 26(4): 496-508.
Publications
- Alvarez M, Benhammou JN, Darci-Maher N, French SW, Han SB, Sinsheimer JS, Agopian VG, Pisegna JR, Pajukanta P. Human liver single nucleus and single�cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival.. Genome medicine, 2022.
- Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Bertram L, Hansen J, Horvath S, Sinsheimer JS, Lill CM, Ritz BR. Erratum to "Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Approach".. Movement disorders : official journal of the Movement Disorder Society, 2022.
- Ko S, German CA, Jensen A, Shen J, Wang A, Mehrotra DV, Sun YV, Sinsheimer JS, Zhou H, Zhou JJ. GWAS of longitudinal trajectories at biobank scale.. American journal of human genetics, 2022.
- Stutz TC, Sinsheimer JS, Sehl M, Xu J. Computational tools for assessing gene therapy under branching process models of mutation.. Bulletin of mathematical biology, 2021.
- Flores YN, Amoon AT, Su B, Velazquez-Cruz R, Ram?rez-Palacios P, Salmer?n J, Rivera-Paredez B, Sinsheimer JS, Lusis AJ, Huertas-Vazquez A, Saab S, Glenn BA, May FP, Williams KJ, Bastani R, Bensinger SJ. Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico.. Lipids in health and disease, 2021.
- Chang CC, Huang ZY, Shih SF, Luo Y, Ko A, Cui Q, Sumner J, Cavallero S, Das S, Gao W, Sinsheimer J, Bui A, Jacobs JP, Pajukanta P, Wu H, Tai YC, Li Z, Hsiai TK. Electrical impedance tomography for non-invasive identification of fatty liver infiltrate in overweight individuals.. Scientific reports, 2021.
- Pan DZ, Miao Z, Comenho C, Rajkumar S, Koka A, Lee SHT, Alvarez M, Kaminska D, Ko A, Sinsheimer JS, Mohlke KL, Mancuso N, Mu?oz-Hernandez LL, Herrera-Hernandez M, Tusi?-Luna MT, Aguilar-Salinas C, Pietil?inen KH, Pihlajam?ki J, Laakso M, Garske KM, Pajukanta P. Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.. Genome medicine, 2021.
- Miao Z, Garske KM, Pan DZ, Koka A, Kaminska D, Männistö V, Sinsheimer JS, Pihlajamäki J, Pajukanta P. Identification of 90 NAFLD GWAS loci and establishment of NAFLD PRS and causal role of NAFLD in coronary artery disease.. HGG advances, 2021.
- Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Bertram L, Hansen J, Horvath S, Sinsheimer JS, Lill CM, Ritz BR. Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach.. Movement disorders : official journal of the Movement Disorder Society, 2021.
- Pan DZ, Miao Z, Comenho C, Rajkumar S, Koka A, Lee SHT, Alvarez M, Kaminska D, Ko A, Sinsheimer JS, Mohlke KL, Mancuso N, Mu?oz-Hernandez LL, Herrera-Hernandez M, Tusi?-Luna MT, Aguilar-Salinas C, Pietil?inen KH, Pihlajam?ki J, Laakso M, Garske KM, Pajukanta P. Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.. Genome medicine, 2021.
- German CA, Sinsheimer JS, Zhou J, Zhou H. WiSER: Robust and scalable estimation and inference of within-subject variances from intensive longitudinal data.. Biometrics, 2021.
- Chu BB, Sobel EM, Wasiolek R, Ko S, Sinsheimer JS, Zhou H, Lange K. A fast Data-Driven method for genotype imputation, phasing, and local ancestry inference: MendelImpute.jl.. Bioinformatics (Oxford, England), 2021.
- Landeros A, Ji X, Lange K, Stutz TC, Xu J, Sehl ME, Sinsheimer JS. An examination of school reopening strategies during the SARS-CoV-2 pandemic.. PloS one, 2021.
- Ji SS, German CA, Lange K, Sinsheimer JS, Zhou H, Zhou J, Sobel EM. Modern simulation utilities for genetic analysis.. BMC bioinformatics, 2021.
- Landeros A, Ji X, Lange K, Stutz TC, Xu J, Sehl ME, Sinsheimer JS. An examination of school reopening strategies during the SARS-CoV-2 pandemic.. medRxiv : the preprint server for health sciences, 2021.
- Stutz TC, Landeros A, Xu J, Sinsheimer JS, Sehl M, Lange K. Stochastic simulation algorithms for Interacting Particle Systems.. PloS one, 2021.
- Bryant L, Li D, Cox SG, Marchione D, Joiner EF, Wilson K, Janssen K, Lee P, March ME, Nair D, Sherr E, Fregeau B, Wierenga KJ, Wadley A, Mancini GMS, Powell-Hamilton N, van de Kamp J, Grebe T, Dean J, Ross A, Crawford HP, Powis Z, Cho MT, Willing MC, Manwaring L, Schot R, Nava C, Afenjar A, Lessel D, Wagner M, Klopstock T, Winkelmann J, Catarino CB, Retterer K, Schuette JL, Innis JW, Pizzino A, L?ttgen S, Denecke J, Strom TM, Monaghan KG, DDD Study, Yuan ZF, Dubbs H, Bend R, Lee JA, Lyons MJ, Hoefele J, G?nthner R, Reutter H, Keren B, Radtke K, Sherbini O, Mrokse C, Helbig KL, Odent S, Cogne B, Mercier S, Bezieau S, Besnard T, Kury S, Redon R, Reinson K, Wojcik MH, ?unap K, Ilves P, Innes AM, Kernohan KD, Care4Rare Canada Consortium, Costain G, Meyn MS, Chitayat D, Zackai E, Lehman A, Kitson H, CAUSES Study, Martin MG, Martinez-Agosto JA, Undiagnosed Diseases Network, Nelson SF, Palmer CGS, Papp JC, Parker NH, Sinsheimer JS, Vilain E, Wan J, Yoon AJ, Zheng A, Brimble E, Ferrero GB, Radio FC, Carli D, Barresi S, Brusco A, Tartaglia M, Thomas JM, Umana L, Weiss MM, Gotway G, Stuurman KE, Thompson ML, McWalter K, Stumpel CTRM, Stevens SJC, Stegmann APA, Tveten K, V?llo A, Prescott T, Fagerberg C, Laulund LW, Larsen MJ, Byler M, Lebel RR, Hurst AC, Dean J, Schrier Vergano SA, Norman J, Mercimek-Andrews S, Neira J, Van Allen MI, Longo N, Sellars E, Louie RJ, Cathey SS, Brokamp E, Heron D, Snyder M, Vanderver A, Simon C, de la Cruz X, Padilla N, Crump JG, Chung W, Garcia B, Hakonarson HH, Bhoj EJ. Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients.. Science advances, 2020.
- Crandall CJ, Diamant AL, Maglione M, Thurston RC, Sinsheimer J. Genetic Variation and Hot Flashes: A Systematic Review.. The Journal of clinical endocrinology and metabolism, 2020.
- Hung TKW, Dong TS, Chen Z, Elashoff D, Sinsheimer JS, Jacobs JP, Lagishetty V, Vora P, Stains J, Mayer EA, Gupta A. Understanding the Heterogeneity of Obesity and the Relationship to the Brain-Gut Axis.. Nutrients, 2020.
- Studwell CM, Kelley EG, Undiagnosed Diseases Network, Sinsheimer JS, Palmer CGS, LeBlanc K. Family genetic result communication in rare and undiagnosed disease communities: Understanding the practice.. Journal of genetic counseling, 2020.
- Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. Correction to: A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders.. Journal of neurovirology, 2020.
- Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Dobricic V, Tysnes OB, Bertram L, Alves G, Sinsheimer JS, Lill CM, Maple-Gr?dem J, Ritz BR. Genetic risk scores and hallucinations in patients with Parkinson disease.. Neurology. Genetics, 2020.
- Chu BB, Keys KL, German CA, Zhou H, Zhou JJ, Sobel EM, Sinsheimer JS, Lange K. Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity.. GigaScience, 2020.
- Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders.. Journal of neurovirology, 2020.
- vonHoldt BM, DeCandia AL, Heppenheimer E, Janowitz-Koch I, Shi R, Zhou H, German CA, Brzeski KE, Cassidy KA, Stahler DR, Sinsheimer JS. Heritability of interpack aggression in a wild pedigreed population of North American grey wolves.. Molecular ecology, 2020.
- German CA, Sinsheimer JS, Klimentidis YC, Zhou H, Zhou JJ. Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale.. Genetic epidemiology, 2019.
- Shih IF, Haan MN, Paul KC, Yu Y, Sinsheimer JS, Ritz B. The Roles of Physical Activity and Inflammation in Mortality, Cognition, and Depressive Symptoms Among Older Mexican Americans.. American journal of epidemiology, 2019.
- Lee H, Huang AY, Wang LK, Yoon AJ, Renteria G, Eskin A, Signer RH, Dorrani N, Nieves-Rodriguez S, Wan J, Douine ED, Woods JD, Dell'Angelica EC, Fogel BL, Martin MG, Butte MJ, Parker NH, Wang RT, Shieh PB, Wong DA, Gallant N, Singh KE, Tavyev Asher YJ, Sinsheimer JS, Krakow D, Loo SK, Allard P, Papp JC, Undiagnosed Diseases Network, Palmer CGS, Martinez-Agosto JA, Nelson SF. Diagnostic utility of transcriptome sequencing for rare Mendelian diseases.. Genetics in medicine : official journal of the American College of Medical Genetics, 2019.
- Garske KM, Pan DZ, Miao Z, Bhagat YV, Comenho C, Robles CR, Benhammou JN, Alvarez M, Ko A, Ye CJ, Pisegna JR, Mohlke KL, Sinsheimer JS, Laakso M, Pajukanta P. Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.. Nature metabolism, 2019.
- Soontornniyomkij V, Moore DJ, Gouaux B, Soontornniyomkij B, Sinsheimer JS, Levine AJ. Associations of regional amyloid-� plaque and phospho-tau pathology with biological factors and neuropsychological functioning among HIV-infected adults.. Journal of neurovirology, 2019.
- Zhou H, Sinsheimer JS, Bates DM, Chu BB, German CA, Ji SS, Keys KL, Kim J, Ko S, Mosher GD, Papp JC, Sobel EM, Zhai J, Zhou JJ, Lange K. OPENMENDEL: a cooperative programming project for statistical genetics.. Human genetics, 2019.
- Chuang YH, Paul KC, Sinsheimer JS, Bronstein JM, Bordelon YM, Ritz B. Genetic variants in nicotinic receptors and smoking cessation in Parkinson's disease.. Parkinsonism & related disorders, 2019.
- Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.. G3 (Bethesda, Md.), 2018.
- Landeros A, Stutz T, Keys KL, Alekseyenko A, Sinsheimer JS, Lange K, Sehl ME. BioSimulator.jl: Stochastic simulation in Julia.. Computer methods and programs in biomedicine, 2018.
- Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, Mohlke KL, Laakso M, Pajukanta P, Ko A. Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.. Nature communications, 2018.
- Lake JA, Larsen J, Tran DT, Sinsheimer JS. Uncovering the Genomic Origins of Life.. Genome biology and evolution, 2018.
- vonHoldt BM, Ji SS, Aardema ML, Stahler DR, Udell MAR, Sinsheimer JS. Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome.. Genome biology and evolution, 2018.
- Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, Mohlke KL, Laakso M, Pajukanta P, Ko A. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.. Nature communications, 2018.
- Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. NFE2L2, PPARGC1a, and pesticides and Parkinson's disease risk and progression.. Mechanisms of ageing and development, 2018.
- Gilbert PS, Wu J, Simon MW, Sinsheimer JS, Alfaro ME. Filtering nucleotide sites by phylogenetic signal to noise ratio increases confidence in the Neoaves phylogeny generated from ultraconserved elements.. Molecular phylogenetics and evolution, 2018.
- Palmer CGS, McConkie-Rosell A, Holm IA, LeBlanc K, Sinsheimer JS, Briere LC, Dorrani N, Herzog MR, Lincoln S, Schoch K, Spillmann RC, Brokamp E, Undiagnosed Diseases Network. Understanding Adult Participant and Parent Empowerment Prior to Evaluation in the Undiagnosed Diseases Network.. Journal of genetic counseling, 2018.
- Bolanos R, Martinez-Maza O, Zhang ZF, Hussain S, Sehl M, Sinsheimer JS, D'Souza G, Jenkins F, Wolinsky S, Detels R. Decreased levels of the serum inflammatory biomarkers, sGP130, IL-6, sCRP and BAFF, are associated with increased likelihood of AIDS related Kaposi's sarcoma in men who have sex with men.. Cancer research frontiers, 2018.
- Boudreault P, Wolfson A, Berman B, Venne VL, Sinsheimer JS, Palmer C. Bilingual Cancer Genetic Education Modules for the Deaf Community: Development and Evaluation of the Online Video Material.. Journal of genetic counseling, 2017.
- Kusters CDJ, Paul KC, Guella I, Bronstein JM, Sinsheimer JS, Farrer MJ, Ritz BR. Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson's disease.. Parkinsonism & related disorders, 2017.
- vonHoldt BM, Shuldiner E, Koch IJ, Kartzinel RY, Hogan A, Brubaker L, Wanser S, Stahler D, Wynne CDL, Ostrander EA, Sinsheimer JS, Udell MAR. Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs.. Science advances, 2017.
- Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. Organophosphate pesticides and PON1 L55M in Parkinson's disease progression.. Environment international, 2017.
- Lorenzo Bermejo J, Boekstegers F, González Silos R, Marcelain K, Baez Benavides P, Barahona Ponce C, Müller B, Ferreccio C, Koshiol J, Fischer C, Peil B, Sinsheimer J, Fuentes Guajardo M, Barajas O, Gonzalez-Jose R, Bedoya G, Cátira Bortolini M, Canizales-Quinteros S, Gallo C, Ruiz Linares A, Rothhammer F. Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile.. PLoS genetics, 2017.
- Crandall CJ, Manson JE, Hohensee C, Horvath S, Wactawski-Wende J, LeBlanc ES, Vitolins MZ, Nassir R, Sinsheimer JS. Association of genetic variation in the tachykinin receptor 3 locus with hot flashes and night sweats in the Women's Health Initiative Study.. Menopause (New York, N.Y.), 2017.
- Clark MM, Chazara O, Sobel EM, Gjessing HK, Magnus P, Moffett A, Sinsheimer JS. Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes.. Human heredity, 2017.
- Cybis GB, Sinsheimer JS, Bedford T, Rambaut A, Lemey P, Suchard MA. Bayesian nonparametric clustering in phylogenetics: modeling antigenic evolution in influenza.. Statistics in medicine, 2017.
- Fejzo MS, Myhre R, Colodro-Conde L, MacGibbon KW, Sinsheimer JS, Reddy MVPL, Pajukanta P, Nyholt DR, Wright MJ, Martin NG, Engel SM, Medland SE, Magnus P, Mullin PM. Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2).. Molecular and cellular endocrinology, 2016.
- Lee PC, Raaschou-Nielsen O, Lill CM, Bertram L, Sinsheimer JS, Hansen J, Ritz B. Gene-environment interactions linking air pollution and inflammation in Parkinson's disease.. Environmental research, 2016.
- Gatto NM, Paul KC, Sinsheimer JS, Bronstein JM, Bordelon Y, Rausch R, Ritz B. Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson's disease.. Journal of the neurological sciences, 2016.
- Palmer CG, Boudreault P, Berman BA, Wolfson A, Duarte L, Venne VL, Sinsheimer JS. Bilingual approach to online cancer genetics education for Deaf American Sign Language users produces greater knowledge and confidence than English text only: A randomized study.. Disability and health journal, 2016.
- Paul KC, Rausch R, Creek MM, Sinsheimer JS, Bronstein JM, Bordelon Y, Ritz B. APOE, MAPT, and COMT and Parkinson's Disease Susceptibility and Cognitive Symptom Progression.. Journal of Parkinson's disease, 2016.
- Lake JA, Larsen J, Sarna B, de la Haba RR, Pu Y, Koo H, Zhao J, Sinsheimer JS. Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria.. Genome biology and evolution, 2016.
- Chuang YH, Lill CM, Lee PC, Hansen J, Lassen CF, Bertram L, Greene N, Sinsheimer JS, Ritz B. Gene-Environment Interaction in Parkinson's Disease: Coffee, ADORA2A, and CYP1A2.. Neuroepidemiology, 2016.
- Janowitz Koch I, Clark MM, Thompson MJ, Deere-Machemer KA, Wang J, Duarte L, Gnanadesikan GE, McCoy EL, Rubbi L, Stahler DR, Pellegrini M, Ostrander EA, Wayne RK, Sinsheimer JS, vonHoldt BM. The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves.. Molecular ecology, 2016.
- Lake JA, Larsen J, Sarna B, de la Haba RR, Pu Y, Koo H, Zhao J, Sinsheimer JS. Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria.. Genome biology and evolution, 2015.
- Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ. Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV.. Journal of neurovirology, 2015.
- Clark MM, Blangero J, Dyer TD, Sobel EM, Sinsheimer JS. The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions.. Annals of human genetics, 2015.
- Narayan S, Sinsheimer JS, Paul KC, Liew Z, Cockburn M, Bronstein JM, Ritz B. Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.. Environmental research, 2015.
- Paul KC, Sinsheimer JS, Rhodes SL, Cockburn M, Bronstein J, Ritz B. Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson's Disease, California (USA).. Environmental health perspectives, 2015.
- Gilbert PS, Chang J, Pan C, Sobel EM, Sinsheimer JS, Faircloth BC, Alfaro ME. Genome-wide ultraconserved elements exhibit higher phylogenetic informativeness than traditional gene markers in percomorph fishes.. Molecular phylogenetics and evolution, 2015.
- Cybis GB, Sinsheimer JS, Bedford T, Mather AE, Lemey P, Suchard MA. ASSESSING PHENOTYPIC CORRELATION THROUGH THE MULTIVARIATE PHYLOGENETIC LATENT LIABILITY MODEL.. The annals of applied statistics, 2015.
- Huertas-Vazquez A, Nelson CP, Sinsheimer JS, Reinier K, Uy-Evanado A, Teodorescu C, Ayala J, Hall AS, Gunson K, Jui J, Samani NJ, Chugh SS. Cumulative effects of common genetic variants on risk of sudden cardiac death.. International journal of cardiology. Heart & vasculature, 2015.
- Gatto NM, Sinsheimer JS, Cockburn M, Escobedo LA, Bordelon Y, Ritz B. Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure.. Journal of the neurological sciences, 2015.
- Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Mart?nez-Maza O, Horvath S, Vilain E, Jamieson BD. Acceleration of age-associated methylation patterns in HIV-1-infected adults.. PloS one, 2015.
- Palmer CG, Boudreault P, Baldwin EE, Sinsheimer JS. Impact of genetic counseling and Connexin-26 and Connexin-30 testing on deaf identity and comprehension of genetic test results in a sample of deaf adults: a prospective, longitudinal study.. PloS one, 2014.
- Han E, Sinsheimer JS, Novembre J. Fast and accurate site frequency spectrum estimation from low coverage sequence data.. Bioinformatics (Oxford, England), 2014.
- Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, S?nchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome.. Archives of sexual behavior, 2014.
- Anastasopoulos E, Coleman AL, Wilson MR, Sinsheimer JS, Yu F, Katafigiotis S, Founti P, Salonikiou A, Pappas T, Koskosas A, Katopodi T, Lambropoulos A, Topouzis F. Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study.. Investigative ophthalmology & visual science, 2014.
- Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Mu?oz-Hern?ndez LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heli?vaara M, Raitakari O, Lehtim?ki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.. Nature communications, 2014.
- Arboleda VA, Fleming A, Barseghyan H, D?lot E, Sinsheimer JS, Vilain E. Regulation of sex determination in mice by a non-coding genomic region.. Genetics, 2014.
- Levine AJ, Reynolds S, Cox C, Miller EN, Sinsheimer JS, Becker JT, Martin E, Sacktor N, Neuropsychology Working Group of the Multicenter AIDS Cohort Study. The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning.. Journal of neurovirology, 2014.
- Lange K, Papp JC, Sinsheimer JS, Sobel EM. Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data.. Annual review of statistics and its application, 2014.
- Han E, Sinsheimer JS, Novembre J. Characterizing bias in population genetic inferences from low-coverage sequencing data.. Molecular biology and evolution, 2013.
- Kobayashi Y, Boudreault P, Hill K, Sinsheimer JS, Palmer CG. Using a social marketing framework to evaluate recruitment of a prospective study of genetic counseling and testing for the deaf community.. BMC medical research methodology, 2013.
- Rhodes SL, Buchanan DD, Ahmed I, Taylor KD, Loriot MA, Sinsheimer JS, Bronstein JM, Elbaz A, Mellick GD, Rotter JI, Ritz B. Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin.. Neurobiology of disease, 2013.
- Narayan S, Liew Z, Paul K, Lee PC, Sinsheimer JS, Bronstein JM, Ritz B. Household organophosphorus pesticide use and Parkinson's disease.. International journal of epidemiology, 2013.
- Rhodes SL, Fitzmaurice AG, Cockburn M, Bronstein JM, Sinsheimer JS, Ritz B. Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson?s disease.. Environmental research, 2013.
- Panos SE, Hinkin CH, Singer EJ, Thames AD, Patel SM, Sinsheimer JS, Del Re AC, Gelman BB, Morgello S, Moore DJ, Levine AJ. Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity.. Neurobehavioral HIV medicine, 2013.
- Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM. Mendel: the Swiss army knife of genetic analysis programs.. Bioinformatics (Oxford, England), 2013.
- Lee PC, Rhodes SL, Sinsheimer JS, Bronstein J, Ritz B. Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure.. Environment international, 2013.
- Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Mu?oz-Hernandez LL, Gomez-Munguia L, Ordo?ez-S?nchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, Sinsheimer JS, Tusie-Luna T, Pajukanta P. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.. Journal of medical genetics, 2013.
- Palmer CG, Boudreault P, Baldwin EE, Fox M, Deignan JL, Kobayashi Y, Sininger Y, Grody W, Sinsheimer JS. Deaf genetic testing and psychological well-being in deaf adults.. Journal of genetic counseling, 2013.
- Cybis GB, Sinsheimer JS, Lemey P, Suchard MA. Graph hierarchies for phylogeography.. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013.
- Lake JA, Sinsheimer JS. The deep roots of the rings of life.. Genome biology and evolution, 2013.
- Riley L, Zhou H, Lange K, Sinsheimer JS, Sehl ME. Determining duration of HER2-targeted therapy using stem cell extinction models.. PloS one, 2012.
- Reddy MV, Iatan I, Weissglas-Volkov D, Nikkola E, Haas BE, Juvonen M, Ruel I, Ruel MJ, Sinsheimer JS, Genest J, Pajukanta P. Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family.. Circulation. Cardiovascular genetics, 2012.
- Anastasopoulos E, Kakoulidou A, Coleman AL, Sinsheimer JS, Wilson MR, Yu F, Salonikiou A, Koskosas A, Pappas T, Founti P, Lambropoulos A, Topouzis F. Association of sequence variation in the CX3CR1 gene with geographic atrophy age-related macular degeneration in a Greek population.. Current eye research, 2012.
- Sinsheimer JS, Little RJ, Lake JA. Rooting gene trees without outgroups: EP rooting.. Genome biology and evolution, 2012.
- Tom JA, Sinsheimer JS, Suchard MA. Does history repeat itself? Wavelets and the phylodynamics of influenza A.. Molecular biology and evolution, 2011.
- Zhou JJ, Ghazalpour A, Sobel EM, Sinsheimer JS, Lange K. Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses.. Genetics, 2011.
- Deere KA, Grether GF, Sun A, Sinsheimer JS. Female mate preference explains countergradient variation in the sexual coloration of guppies (Poecilia reticulata).. Proceedings. Biological sciences, 2011.
- Levine AJ, Sinsheimer JS, Bilder R, Shapshak P, Singer EJ. Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults.. Journal of clinical and experimental neuropsychology, 2011.
- Childs EJ, Sobel EM, Palmer CG, Sinsheimer JS. Detection of intergenerational genetic effects with application to HLA-B matching as a risk factor for schizophrenia.. Human heredity, 2011.
- Sehl M, Zhou H, Sinsheimer JS, Lange KL. Extinction models for cancer stem cell therapy.. Mathematical biosciences, 2011.
- Sinsheimer J. "Statistics 101"--a primer for the genetics of complex human disease.. Cold Spring Harbor protocols, 2011.
- Baldwin EE, Boudreault P, Fox M, Sinsheimer JS, Palmer CG. Effect of pre-test genetic counseling for deaf adults on knowledge of genetic testing.. Journal of genetic counseling, 2011.
- Weissglas-Volkov D, Calkin AC, Tusie-Luna T, Sinsheimer JS, Zelcer N, Riba L, Tino AM, Ordo?ez-S?nchez ML, Cruz-Bautista I, Aguilar-Salinas CA, Tontonoz P, Pajukanta P. The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.. The Journal of clinical investigation, 2011.
- Bocklandt S, Lin W, Sehl ME, S?nchez FJ, Sinsheimer JS, Horvath S, Vilain E. Epigenetic predictor of age.. PloS one, 2011.
- Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Comparative analysis of proteome and transcriptome variation in mouse.. PLoS genetics, 2011.
- Suwanwela J, Lee J, Lin A, Ucer TC, Devlin H, Sinsheimer J, Garrett NR, Nishimura I. A genetic association study of single nucleotide polymorphisms in FGFR1OP2/wit3.0 and long-term atrophy of edentulous mandible.. PloS one, 2011.
- Rhodes SL, Sinsheimer JS, Bordelon Y, Bronstein JM, Ritz B. Replication of GWAS associations for GAK and MAPT in Parkinson's disease.. Annals of human genetics, 2010.
- Zhou H, Sehl ME, Sinsheimer JS, Lange K. Association screening of common and rare genetic variants by penalized regression.. Bioinformatics (Oxford, England), 2010.
- Sinsheimer JS, Elston RC, Fu WJ. Gene-gene interaction in maternal and perinatal research.. Journal of biomedicine & biotechnology, 2010.
- Childs EJ, Palmer CG, Lange K, Sinsheimer JS. Modeling maternal-offspring gene-gene interactions: the extended-MFG test.. Genetic epidemiology, 2010.
- Boudreault P, Baldwin EE, Fox M, Dutton L, Tullis L, Linden J, Kobayashi Y, Zhou J, Sinsheimer JS, Sininger Y, Grody WW, Palmer CG. Deaf adults' reasons for genetic testing depend on cultural affiliation: results from a prospective, longitudinal genetic counseling and testing study.. Journal of deaf studies and deaf education, 2010.
- van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice.. Genetics, 2010.
- Cantor RM, Lange K, Sinsheimer JS. Prioritizing GWAS results: A review of statistical methods and recommendations for their application.. American journal of human genetics, 2010.
- Tom JA, Sinsheimer JS, Suchard MA. Reuse, Recycle, Reweigh: Combating Influenza through Efficient Sequential Bayesian Computation for Massive Data.. The annals of applied statistics, 2010.
- Sehl ME, Sinsheimer JS, Zhou H, Lange KL. Differential destruction of stem cells: implications for targeted cancer stem cell therapy.. Cancer research, 2009.
- Weissglas-Volkov D, Aguilar-Salinas CA, Sinsheimer JS, Riba L, Huertas-Vazquez A, Ordo?ez-S?nchez ML, Rodriguez-Guillen R, Cantor RM, Tusie-Luna T, Pajukanta P. Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.. Circulation. Cardiovascular genetics, 2009.
- Weissglas-Volkov D, Plaisier CL, Huertas-Vazquez A, Cruz-Bautista I, Riaño-Barros D, Herrera-Hernandez M, Riba L, Cantor RM, Sinsheimer JS, Aguilar-Salinas CA, Tusie-Luna T, Pajukanta P. Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans.. Arteriosclerosis, thrombosis, and vascular biology, 2009.
- Levine AJ, Singer EJ, Sinsheimer JS, Hinkin CH, Papp J, Dandekar S, Giovanelli A, Shapshak P. CCL3 genotype and current depression increase risk of HIV-associated dementia.. Neurobehavioral HIV medicine, 2009.
- Bonneaud C, Sinsheimer JS, Richard M, Chastel O, Sorci G. Mhc polymorphisms fail to explain the heritability of phytohaemagglutinin-induced skin swelling in a wild passerine.. Biology letters, 2009.
- Meex SJ, Weissglas-Volkov D, van der Kallen CJ, Thuerauf DJ, van Greevenbroek MM, Schalkwijk CG, Stehouwer CD, Feskens EJ, Heldens L, Ayoubi TA, Hofker MH, Wouters BG, Vlietinck R, Sinsheimer JS, Taskinen MR, Kuusisto J, Laakso M, de Bruin TW, Pajukanta P, Glembotski CC. The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels.. Arteriosclerosis, thrombosis, and vascular biology, 2009.
- Sinsheimer J. Statistical genetic approaches for mapping ophthalmic trait and disease genes.. American journal of ophthalmology, 2009.
- Crandall CJ, Sehl ME, Crawford SL, Gold EB, Habel LA, Butler LM, Sowers MR, Greendale GA, Sinsheimer JS. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.. Breast cancer research : BCR, 2009.
- Zhou JJ, Lange K, Papp JC, Sinsheimer JS. A heterozygote-homozygote test of Hardy-Weinberg equilibrium.. European journal of human genetics : EJHG, 2009.
- Sehl ME, Langer LR, Papp JC, Kwan L, Seldon JL, Arellano G, Reiss J, Reed EF, Dandekar S, Korin Y, Sinsheimer JS, Zhang ZF, Ganz PA. Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009.
- Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez-Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. Galanin preproprotein is associated with elevated plasma triglycerides.. Arteriosclerosis, thrombosis, and vascular biology, 2008.
- Bauman LE, Sinsheimer JS, Sobel EM, Lange K. Mixed effects models for quantitative trait loci mapping with inbred strains.. Genetics, 2008.
- Palmer CG, Mallery E, Turunen JA, Hsieh HJ, Peltonen L, Lonnqvist J, Woodward JA, Sinsheimer JS. Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex.. Schizophrenia research, 2008.
- Nikolova G, Sinsheimer JS, Eicher EM, Vilain E. The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice.. Genetics, 2008.
- Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF. A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers.. International journal of cancer, 2008.
- Seitzman RL, Mahajan VB, Mangione C, Cauley JA, Ensrud KE, Stone KL, Cummings SR, Hochberg MC, Hillier TA, Sinsheimer JS, Yu F, Coleman AL, Study of Osteoporotic Fractures Research Group. Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.. American journal of epidemiology, 2008.
- Sinsheimer JS, Plaisier CL, Huertas-Vazquez A, Aguilar-Salinas C, Tusie-Luna T, Pajukanta P, Lange K. Estimating ethnic admixture from pedigree data.. American journal of human genetics, 2008.
- Hsieh HJ, Palmer CG, Harney S, Chen HW, Bauman L, Brown MA, Sinsheimer JS. Using the maternal-fetal genotype incompatibility test to assess non-inherited maternal HLA-DRB1 antigen coding alleles as rheumatoid arthritis risk factors.. BMC proceedings, 2007.
- Lee JC, Weissglas-Volkov D, Kyttälä M, Sinsheimer JS, Jokiaho A, de Bruin TW, Lusis AJ, Brennan ML, van Greevenbroek MM, van der Kallen CJ, Hazen SL, Pajukanta P. USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.. Arteriosclerosis, thrombosis, and vascular biology, 2007.
- Wahner AD, Sinsheimer JS, Bronstein JM, Ritz B. Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease.. Archives of neurology, 2007.
- Loughlin J, Meulenbelt I, Min J, Mustafa Z, Sinsheimer JS, Carr A, Slagboom PE. Genetic association analysis of RHOB and TXNDC3 in osteoarthritis.. American journal of human genetics, 2007.
- Hsieh HJ, Palmer CG, Sinsheimer JS. Allowing for missing data at highly polymorphic genes when testing for maternal, offspring and maternal-fetal genotype incompatibility effects.. Human heredity, 2006.
- Nikolova G, Lee H, Berkovitz S, Nelson S, Sinsheimer J, Vilain E, Rodríguez LV. Sequence variant in the laminin gamma1 (LAMC1) gene associated with familial pelvic organ prolapse.. Human genetics, 2006.
- Kim S, Kim Y, Liang T, Sinsheimer JS, Chow SA. A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites.. Journal of virology, 2006.
- Palmer CG, Hsieh HJ, Reed EF, Lonnqvist J, Peltonen L, Woodward JA, Sinsheimer JS. HLA-B maternal-fetal genotype matching increases risk of schizophrenia.. American journal of human genetics, 2006.
- Hsieh HJ, Palmer CG, Harney S, Newton JL, Wordsworth P, Brown MA, Sinsheimer JS. The v-MFG test: investigating maternal, offspring and maternal-fetal genetic incompatibility effects on disease and viability.. Genetic epidemiology, 2006.
- Chapman K, Carr A, Loughlin J, Sinsheimer JS. Presence of a primary hip osteoarthritis susceptibility locus on chromosome 6: comment on the article by Meenagh et al.. Arthritis and rheumatism, 2006.
- Mustafa Z, Dowling B, Chapman K, Sinsheimer JS, Carr A, Loughlin J. Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.. Arthritis and rheumatism, 2005.
- Suchard MA, Weiss RE, Sinsheimer JS. Models for estimating bayes factors with applications to phylogeny and tests of monophyly.. Biometrics, 2005.
- Kraft P, Hsieh HJ, Cordell HJ, Sinsheimer J. A conditional-on-exchangeable-parental-genotypes likelihood that remains unbiased at the causal locus under multiple-affected-sibling ascertainment.. Genetic epidemiology, 2005.
- Lange K, Sinsheimer JS, Sobel E. Association testing with Mendel.. Genetic epidemiology, 2005.
- Minassian SL, Palmer CG, Sinsheimer JS. An exact maternal-fetal genotype incompatibility (MFG) test.. Genetic epidemiology, 2005.
- Fang G, Kuiken C, Weiser B, Rowland-Jones S, Plummer F, Chen CH, Kaul R, Anzala AO, Bwayo J, Kimani J, Philpott SM, Kitchen C, Sinsheimer JS, Gaschen B, Lang D, Shi B, Kemal KS, Rostron T, Brunner C, Beddows S, Sattenau Q, Paxinos E, Oyugi J, Burger H. Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations.. The Journal of infectious diseases, 2004.
- Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ. Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia.. Circulation research, 2004.
- Kraft P, Palmer CG, Woodward AJ, Turunen JA, Minassian S, Paunio T, Lönnqvist J, Peltonen L, Sinsheimer JS. RHD maternal-fetal genotype incompatibility and schizophrenia: extending the MFG test to include multiple siblings and birth order.. European journal of human genetics : EJHG, 2004.
- Pajukanta P, Lilja HE, Sinsheimer JS, Cantor RM, Lusis AJ, Gentile M, Duan XJ, Soro-Paavonen A, Naukkarinen J, Saarela J, Laakso M, Ehnholm C, Taskinen MR, Peltonen L. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).. Nature genetics, 2004.
- Lange K, Sinsheimer JS. The pedigree trimming problem.. Human heredity, 2004.
- Suchard MA, Kitchen CM, Sinsheimer JS, Weiss RE. Hierarchical phylogenetic models for analyzing multipartite sequence data.. Systematic biology, 2003.
- Duncan EL, Cardon LR, Sinsheimer JS, Wass JA, Brown MA. Site and gender specificity of inheritance of bone mineral density.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2003.
- Suchard MA, Weiss RE, Sinsheimer JS. Testing a molecular clock without an outgroup: derivations of induced priors on branch-length restrictions in a Bayesian framework.. Systematic biology, 2003.
- Sinsheimer JS, Suchard MA, Dorman KS, Fang F, Weiss RE. Are you my mother? Bayesian phylogenetic inference of recombination among putative parental strains.. Applied bioinformatics, 2003.
- Sinsheimer JS, Palmer CG, Woodward JA. Detecting genotype combinations that increase risk for disease: maternal-fetal genotype incompatibility test.. Genetic epidemiology, 2003.
- Palmer CG, Turunen JA, Sinsheimer JS, Minassian S, Paunio T, Lönnqvist J, Peltonen L, Woodward JA. RHD maternal-fetal genotype incompatibility increases schizophrenia susceptibility.. American journal of human genetics, 2002.
- Suchard MA, Weiss RE, Dorman KS, Sinsheimer JS. Oh brother, where art thou? A Bayes factor test for recombination with uncertain heritage.. Systematic biology, 2002.
- Schadt EE, Sinsheimer JS, Lange K. Applications of codon and rate variation models in molecular phylogeny.. Molecular biology and evolution, 2002.
- Auranen M, Vanhala R, Varilo T, Ayers K, Kempas E, Ylisaukko-Oja T, Sinsheimer JS, Peltonen L, Järvelä I. A genomewide screen for autism-spectrum disorders: evidence for a major susceptibility locus on chromosome 3q25-27.. American journal of human genetics, 2002.
- Dorman KS, Kaplan AH, Sinsheimer JS. Bootstrap confidence levels for HIV-1 recombination.. Journal of molecular evolution, 2002.