
Janet S Sinsheimer
Professor, Human Genetics, University of California Los Angeles
Professor, Computational Medicine, University of California Los Angeles
5-357C Gonda / 5213 LSB
Los Angeles, CA 90095 Gonda Center
Los Angeles, CA 90095
Affiliations
Member, Bioinformatics GPB Home Area, CTSI, Genetics & Genomics GPB Home Area, JCCC Healthy and At-Risk Populations Program Area, JCCC Molecular Epidemiology Program Area
Research Interests
Dr. Sinsheimer’s research is focused on developing mathematical models of evolution and genetics. Her research program involves the development and application of statistical methodology for mapping complex trait and disease genes. Most recently, her group have been working on statistical methods for detecting disease genes acting through maternal-fetal genotype incompatibility and models to disentangle maternal genetic effects from environment. She has also developed methods for realistic inference of evolutionary relationships in a Bayesian context and applied these methods to HIV evolution. Her research in HIV evolution has been geared towards understanding the mechanisms by which HIV evades the immune system.
Biography
Janet Sinsheimer is a Professor in the Departments of Human Genetics, Computational Medicine and Biostatistics at UCLA. She has a PhD in Biomathematics (UCLA), an MA in Biochemistry (Brandeis) and an ScB in Chemistry (Brown U). Dr. Sinsheimer’s research is focused on developing mathematical models for the analysis of genomic and genetic data. She has also developed methods for realistic inference of evolutionary relationships. Most recently, her group has been working on novel statistical methods for detecting disease and trait genes via a variance component paradigm and on methods of rapid inference with big genetic and genomic data sets.
Publications
A selected list of publications:
- Palmer Christina G S, Boudreault Patrick, Baldwin Erin E, Fox Michelle, Deignan Joshua L, Kobayashi Yoko, Sininger Yvonne, Grody Wayne, Sinsheimer Janet S Deaf genetic testing and psychological well-being in deaf adults Journal of genetic counseling, 2013; 22(4): 492-507.
- Lange Kenneth, Papp Jeanette C, Sinsheimer Janet S, Sripracha Ram, Zhou Hua, Sobel Eric M Mendel: the Swiss army knife of genetic analysis programs Bioinformatics (Oxford, England), 2013; 29(12): 1568-70.
- Lee Pei-Chen, Rhodes Shannon L, Sinsheimer Janet S, Bronstein Jeff, Ritz Beate Functional paraoxonase 1 variants modify the risk of Parkinson’s disease due to organophosphate exposure Environment international, 2013; 56(12): 42-7.
- Weissglas-Volkov Daphna, Aguilar-Salinas Carlos A, Nikkola Elina, Deere Kerry A, Cruz-Bautista Ivette, Arellano-Campos Olimpia, Muñoz-Hernandez Linda Liliana, Gomez-Munguia Lizeth, Ordoñez-Sánchez Maria Luisa, Reddy Prasad M V Linga, Lusis Aldons J, Matikainen Niina, Taskinen Marja-Riitta, Riba Laura, Cantor Rita M, Sinsheimer Janet S, Tusie-Luna Teresa, Pajukanta Päivi Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci Journal of medical genetics, 2013; 50(5): 298-308.
- Cybis Gabriela B, Sinsheimer Janet S, Lemey Philippe, Suchard Marc A Graph hierarchies for phylogeography Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013; 368(1614): 20120206.
- Clark Michelle M, Blangero John, Dyer Thomas D, Sobel Eric M, Sinsheimer Janet S The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions Annals of human genetics, 2016; 80(1): 63-80.
- Lange Kenneth, Papp Jeanette C, Sinsheimer Janet S, Sobel Eric M Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data Annual review of statistics and its application, 2014; 1(1): 279-300.
- Clark Michelle M, Chazara Olympe, Sobel Eric M, Gjessing Håkon K, Magnus Per, Moffett Ashley, Sinsheimer Janet S Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes Human heredity, 2016; 81(4): 181-193.
- Cybis Gabriela B, Sinsheimer Janet S, Bedford Trevor, Rambaut Andrew, Lemey Philippe, Suchard Marc A Bayesian nonparametric clustering in phylogenetics: modeling antigenic evolution in influenza Statistics in medicine, 2018; 37(2): 195-206.
- Lake James A, Larsen Joseph, Sarna Brooke, de la Haba Rafael R, Pu Yiyi, Koo HyunMin, Zhao Jun, Sinsheimer Janet S Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria Genome biology and evolution, 2015; 7(12): 3434-42.
- Chuang Yu-Hsuan, Lill Christina M, Lee Pei-Chen, Hansen Johnni, Lassen Christina F, Bertram Lars, Greene Naomi, Sinsheimer Janet S, Ritz Beate Gene-Environment Interaction in Parkinson’s Disease: Coffee, ADORA2A, and CYP1A2 Neuroepidemiology, 2016; 47(3-4): 192-200.
- Boudreault Patrick, Wolfson Alicia, Berman Barbara, Venne Vickie L, Sinsheimer Janet S, Palmer Christina Bilingual Cancer Genetic Education Modules for the Deaf Community: Development and Evaluation of the Online Video Material Journal of genetic counseling, 2017; 37(2): 195-206.
- Narayan Shilpa, Sinsheimer Janet S, Paul Kimberly C, Liew Zeyan, Cockburn Myles, Bronstein Jeff M, Ritz Beate Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson’s disease Environmental research, 2015; 143(Pt A): 98-106.
- Kusters Cynthia D J, Paul Kimberly C, Guella Ilaria, Bronstein Jeff M, Sinsheimer Janet S, Farrer Matt J, Ritz Beate R Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson’s disease Parkinsonism & related disorders, 2017; 37(2): 195-206.
- Gilbert Princess S, Chang Jonathan, Pan Calvin, Sobel Eric M, Sinsheimer Janet S, Faircloth Brant C, Alfaro Michael E Genome-wide ultraconserved elements exhibit higher phylogenetic informativeness than traditional gene markers in percomorph fishes Molecular phylogenetics and evolution, 2015; 92(Pt A): 140-6.
- Paul Kimberly C, Sinsheimer Janet S, Cockburn Myles, Bronstein Jeff M, Bordelon Yvette, Ritz Beate Organophosphate pesticides and PON1 L55M in Parkinson’s disease progression Environment international, 2017; 107(2): 75-81.
- Cybis Gabriela B, Sinsheimer Janet S, Bedford Trevor, Mather Alison E, Lemey Philippe, Suchard Marc A ASSESSING PHENOTYPIC CORRELATION THROUGH THE MULTIVARIATE PHYLOGENETIC LATENT LIABILITY MODEL The annals of applied statistics, 2015; 9(2): 969-991.
- vonHoldt Bridgett M, Shuldiner Emily, Koch Ilana Janowitz, Kartzinel Rebecca Y, Hogan Andrew, Brubaker Lauren, Wanser Shelby, Stahler Daniel, Wynne Clive D L, Ostrander Elaine A, Sinsheimer Janet S, Udell Monique A R Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs Science advances, 2017; 3(7): e1700398.
- Huertas-Vazquez Adriana, Nelson Christopher P, Sinsheimer Janet S, Reinier Kyndaron, Uy-Evanado Audrey, Teodorescu Carmen, Ayala Jo, Hall Alistair S, Gunson Karen, Jui Jonathan, Samani Nilesh J, Chugh Sumeet S Cumulative effects of common genetic variants on risk of sudden cardiac death International journal of cardiology. Heart & vasculature, 2015; 7(2): 88-91.
- Lorenzo Bermejo Justo, Boekstegers Felix, González Silos Rosa, Marcelain Katherine, Baez Benavides Pablo, Barahona Ponce Carol, Müller Bettina, Ferreccio Catterina, Koshiol Jill, Fischer Christine, Peil Barbara, Sinsheimer Janet, Fuentes Guajardo Macarena, Barajas Olga, Gonzalez-Jose Rolando, Bedoya Gabriel, Cátira Bortolini Maria, Canizales-Quinteros Samuel, Gallo Carla, Ruiz Linares Andres, Rothhammer Francisco Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile PLoS genetics, 2017; 13(5): e1006756.
- Gatto Nicole M, Sinsheimer Janet S, Cockburn Myles, Escobedo Loraine A, Bordelon Yvette, Ritz Beate Vitamin D receptor gene polymorphisms and Parkinson’s disease in a population with high ultraviolet radiation exposure Journal of the neurological sciences, 2015; 352(1-2): 88-93.
- Crandall Carolyn J, Manson JoAnn E, Hohensee Chancellor, Horvath Steve, Wactawski-Wende Jean, LeBlanc Erin S, Vitolins Mara Z, Nassir Rami, Sinsheimer Janet S Association of genetic variation in the tachykinin receptor 3 locus with hot flashes and night sweats in the Women’s Health Initiative Study Menopause (New York, N.Y.), 2017; 24(3): 252-261.
- Rickabaugh Tammy M, Baxter Ruth M, Sehl Mary, Sinsheimer Janet S, Hultin Patricia M, Hultin Lance E, Quach Austin, Martínez-Maza Otoniel, Horvath Steve, Vilain Eric, Jamieson Beth D Acceleration of age-associated methylation patterns in HIV-1-infected adults PloS one, 2015; 10(3): e0119201.
- Han Eunjung, Sinsheimer Janet S, Novembre John Fast and accurate site frequency spectrum estimation from low coverage sequence data Bioinformatics (Oxford, England), 2015; 31(5): 720-7.
- Palmer Christina G S, Boudreault Patrick, Berman Barbara A, Wolfson Alicia, Duarte Lionel, Venne Vickie L, Sinsheimer Janet S Bilingual approach to online cancer genetics education for Deaf American Sign Language users produces greater knowledge and confidence than English text only: A randomized study Disability and health journal, 2017; 10(1): 23-32.
- Gatto Nicole M, Paul Kimberly C, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette, Rausch Rebecca, Ritz Beate Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson’s disease Journal of the neurological sciences, 2016; 370(1): 100-106.
- Palmer Christina G S, Boudreault Patrick, Baldwin Erin E, Sinsheimer Janet S Impact of genetic counseling and Connexin-26 and Connexin-30 testing on deaf identity and comprehension of genetic test results in a sample of deaf adults: a prospective, longitudinal study PloS one, 2014; 9(11): e111512.
- Lee Pei-Chen, Raaschou-Nielsen Ole, Lill Christina M, Bertram Lars, Sinsheimer Janet S, Hansen Johnni, Ritz Beate Gene-environment interactions linking air pollution and inflammation in Parkinson’s disease Environmental research, 2016; 151(1): 713-720.
- Arboleda Valerie A, Fleming Alice, Barseghyan Hayk, Délot Emmanuèle, Sinsheimer Janet S, Vilain Eric Regulation of sex determination in mice by a non-coding genomic region Genetics, 2014; 197(3): 885-97.
- Ngun Tuck C, Ghahramani Negar M, Creek Michelle M, Williams-Burris Shayna M, Barseghyan Hayk, Itoh Yuichiro, Sánchez Francisco J, McClusky Rebecca, Sinsheimer Janet S, Arnold Arthur P, Vilain Eric Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome Archives of sexual behavior, 2014; 43(6): 1043-57.
- Levine Andrew J, Soontornniyomkij Virawudh, Achim Cristian L, Masliah Eliezer, Gelman Benjamin B, Sinsheimer Janet S, Singer Elyse J, Moore David J Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV Journal of neurovirology, 2016; 22(4): 431-41.
- Anastasopoulos Eleftherios, Coleman Anne L, Wilson M Roy, Sinsheimer Janet S, Yu Fei, Katafigiotis Sokratis, Founti Panayiota, Salonikiou Angeliki, Pappas Theofanis, Koskosas Archimidis, Katopodi Theodora, Lambropoulos Alexandros, Topouzis Fotis Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study Investigative ophthalmology & visual science, 2014; 55(7): 4238-43.
- Paul Kimberly C, Sinsheimer Janet S, Rhodes Shannon L, Cockburn Myles, Bronstein Jeff, Ritz Beate Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson’s Disease, California (USA) Environmental health perspectives, 2016; 124(5): 570-7.
- Ko Arthur, Cantor Rita M, Weissglas-Volkov Daphna, Nikkola Elina, Reddy Prasad M V Linga, Sinsheimer Janet S, Pasaniuc Bogdan, Brown Robert, Alvarez Marcus, Rodriguez Alejandra, Rodriguez-Guillen Rosario, Bautista Ivette C, Arellano-Campos Olimpia, Muñoz-Hernández Linda L, Salomaa Veikko, Kaprio Jaakko, Jula Antti, Jauhiainen Matti, Heliövaara Markku, Raitakari Olli, Lehtimäki Terho, Eriksson Johan G, Perola Markus, Lohmueller Kirk E, Matikainen Niina, Taskinen Marja-Riitta, Rodriguez-Torres Maribel, Riba Laura, Tusie-Luna Teresa, Aguilar-Salinas Carlos A, Pajukanta Päivi Amerindian-specific regions under positive selection harbour new lipid variants in Latinos Nature communications, 2014; 5(7): 3983.
- Paul Kimberly C, Rausch Rebecca, Creek Michelle M, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette, Ritz Beate APOE, MAPT, and COMT and Parkinson’s Disease Susceptibility and Cognitive Symptom Progression Journal of Parkinson’s disease, 2016; 6(2): 349-59.
- Levine Andrew J, Reynolds Sandra, Cox Christopher, Miller Eric N, Sinsheimer Janet S, Becker James T, Martin Eileen, Sacktor Ned, Sacktor Ned The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning Journal of neurovirology, 2014; 20(3): 243-57.
- Janowitz Koch Ilana, Clark Michelle M, Thompson Michael J, Deere-Machemer Kerry A, Wang Jun, Duarte Lionel, Gnanadesikan Gitanjali E, McCoy Eskender L, Rubbi Liudmilla, Stahler Daniel R, Pellegrini Matteo, Ostrander Elaine A, Wayne Robert K, Sinsheimer Janet S, vonHoldt Bridgett M The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves Molecular ecology, 2016; 25(8): 1838-55.
- Han Eunjung, Sinsheimer Janet S, Novembre John Characterizing bias in population genetic inferences from low-coverage sequencing data Molecular biology and evolution, 2014; 31(3): 723-35.
- Lake James A, Larsen Joseph, Sarna Brooke, de la Haba Rafael R, Pu Yiyi, Koo HyunMin, Zhao Jun, Sinsheimer Janet S Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria Genome biology and evolution, 2016; 8(3): 578.
- Stutz Timothy C, Sinsheimer Janet S, Sehl Mary, Xu Jason Computational tools for assessing gene therapy under branching process models of mutation Bulletin of mathematical biology, 2021; 84(1): 15.
- Kusters Cynthia D J, Paul Kimberly C, Duarte Folle Aline, Keener Adrienne M, Bronstein Jeff M, Bertram Lars, Hansen Johnni, Horvath Steve, Sinsheimer Janet S, Lill Christina M, Ritz Beate R Increased Menopausal Age Reduces the Risk of Parkinson’s Disease: A Mendelian Randomization Approach Movement disorders : official journal of the Movement Disorder Society, 2021; 36(10): 2264-2272.
- Pan David Z, Garske Kristina M, Alvarez Marcus, Bhagat Yash V, Boocock James, Nikkola Elina, Miao Zong, Raulerson Chelsea K, Cantor Rita M, Civelek Mete, Glastonbury Craig A, Small Kerrin S, Boehnke Michael, Lusis Aldons J, Sinsheimer Janet S, Mohlke Karen L, Laakso Markku, Pajukanta Päivi, Ko Arthur Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS Nature communications, 2018; 9(1): 1512.
- Kusters Cynthia D J, Paul Kimberly C, Duarte Folle Aline, Keener Adrienne M, Bronstein Jeff M, Dobricic Valerija, Tysnes Ole-Bjørn, Bertram Lars, Alves Guido, Sinsheimer Janet S, Lill Christina M, Maple-Grødem Jodi, Ritz Beate R Genetic risk scores and hallucinations in patients with Parkinson disease Neurology. Genetics, 2020; 6(5): e492.
- Bolanos Rachel, Martinez-Maza Otoniel, Zhang Zuo-Feng, Hussain Shehnaz, Sehl Mary, Sinsheimer Janet S, D’Souza Gypsyarn, Jenkins Frank, Wolinsky Steven, Detels Roger Decreased levels of the serum inflammatory biomarkers, sGP130, IL-6, sCRP and BAFF, are associated with increased likelihood of AIDS related Kaposi’s sarcoma in men who have sex with men Cancer research frontiers, 2018; 4(1): 45-59.
- Chu Benjamin B, Keys Kevin L, German Christopher A, Zhou Hua, Zhou Jin J, Sobel Eric M, Sinsheimer Janet S, Lange Kenneth Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity GigaScience, 2020; 9(6): e492.
- Flores Yvonne N, Amoon Aryana T, Su Baolong, Velazquez-Cruz Rafael, Ramírez-Palacios Paula, Salmerón Jorge, Rivera-Paredez Berenice, Sinsheimer Janet S, Lusis Aldons J, Huertas-Vazquez Adriana, Saab Sammy, Glenn Beth A, May Folasade P, Williams Kevin J, Bastani Roshan, Bensinger Steven J Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico Lipids in health and disease, 2021; 20(1): 136.
- Fejzo Marlena Schoenberg, Myhre Ronny, Colodro-Conde Lucía, MacGibbon Kimber W, Sinsheimer Janet S, Reddy M V Prasad Linga, Pajukanta Päivi, Nyholt Dale R, Wright Margaret J, Martin Nicholas G, Engel Stephanie M, Medland Sarah E, Magnus Per, Mullin Patrick M Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2) Molecular and cellular endocrinology, 2017; 439(1): 308-316.
- German Christopher A, Sinsheimer Janet S, Klimentidis Yann C, Zhou Hua, Zhou Jin J Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale Genetic epidemiology, 2020; 44(3): 248-260.
- vonHoldt Bridgett M, DeCandia Alexandra L, Heppenheimer Elizabeth, Janowitz-Koch Ilana, Shi Ruoyao, Zhou Hua, German Christopher A, Brzeski Kristin E, Cassidy Kira A, Stahler Daniel R, Sinsheimer Janet S Heritability of interpack aggression in a wild pedigreed population of North American grey wolves Molecular ecology, 2020; 29(10): 1764-1775.
- Chang Chih-Chiang, Huang Zi-Yu, Shih Shu-Fu, Luo Yuan, Ko Arthur, Cui Qingyu, Sumner Jennifer, Cavallero Susana, Das Swarna, Gao Wei, Sinsheimer Janet, Bui Alex, Jacobs Jonathan P, Pajukanta Päivi, Wu Holden, Tai Yu-Chong, Li Zhaoping, Hsiai Tzung K Electrical impedance tomography for non-invasive identification of fatty liver infiltrate in overweight individuals Scientific reports, 2021; 11(1): 19859.
- Rhodes Shannon L, Buchanan Daniel D, Ahmed Ismaïl, Taylor Kent D, Loriot Marie-Anne, Sinsheimer Janet S, Bronstein Jeff M, Elbaz Alexis, Mellick George D, Rotter Jerome I, Ritz Beate Pooled analysis of iron-related genes in Parkinson’s disease: association with transferrin Neurobiology of disease, 2014; 62(1): 172-8.
- Lee Hane, Huang Alden Y, Wang Lee-Kai, Yoon Amanda J, Renteria Genecee, Eskin Ascia, Signer Rebecca H, Dorrani Naghmeh, Nieves-Rodriguez Shirley, Wan Jijun, Douine Emilie D, Woods Jeremy D, Dell’Angelica Esteban C, Fogel Brent L, Martin Martin G, Butte Manish J, Parker Neil H, Wang Richard T, Shieh Perry B, Wong Derek A, Gallant Natalie, Singh Kathryn E, Tavyev Asher Y Jane, Sinsheimer Janet S, Krakow Deborah, Loo Sandra K, Allard Patrick, Papp Jeanette C, Papp Jeanette C, Palmer Christina G S, Martinez-Agosto Julian A, Nelson Stanley F Diagnostic utility of transcriptome sequencing for rare Mendelian diseases Genetics in medicine : official journal of the American College of Medical Genetics, 2020; 22(3): 490-499.
- Kobayashi Yoko, Boudreault Patrick, Hill Karin, Sinsheimer Janet S, Palmer Christina G S Using a social marketing framework to evaluate recruitment of a prospective study of genetic counseling and testing for the deaf community BMC medical research methodology, 2013; 13(1): 145.
- Zhou Hua, Sinsheimer Janet S, Bates Douglas M, Chu Benjamin B, German Christopher A, Ji Sarah S, Keys Kevin L, Kim Juhyun, Ko Seyoon, Mosher Gordon D, Papp Jeanette C, Sobel Eric M, Zhai Jing, Zhou Jin J, Lange Kenneth OPENMENDEL: a cooperative programming project for statistical genetics Human genetics, 2020; 139(1): 61-71.
- Pan David Z, Miao Zong, Comenho Caroline, Rajkumar Sandhya, Koka Amogha, Lee Seung Hyuk T, Alvarez Marcus, Kaminska Dorota, Ko Arthur, Sinsheimer Janet S, Mohlke Karen L, Mancuso Nicholas, Muñoz-Hernandez Linda Liliana, Herrera-Hernandez Miguel, Tusié-Luna Maria Teresa, Aguilar-Salinas Carlos, Pietiläinen Kirsi H, Pihlajamäki Jussi, Laakso Markku, Garske Kristina M, Pajukanta Päivi Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes Genome medicine, 2021; 13(1): 123.
- Soontornniyomkij Virawudh, Moore David J, Gouaux Ben, Soontornniyomkij Benchawanna, Sinsheimer Janet S, Levine Andrew J Associations of regional amyloid-β plaque and phospho-tau pathology with biological factors and neuropsychological functioning among HIV-infected adults Journal of neurovirology, 2019; 25(6): 741-753.
- Chu Benjamin B, Sobel Eric M, Wasiolek Rory, Ko Seyoon, Sinsheimer Janet S, Zhou Hua, Lange Kenneth A fast Data-Driven method for genotype imputation, phasing, and local ancestry inference: MendelImpute.jl Bioinformatics (Oxford, England), 2021; 13(1): 123.
- Shih I-Fan, Haan Mary N, Paul Kimberly C, Yu Yu, Sinsheimer Janet S, Ritz Beate The Roles of Physical Activity and Inflammation in Mortality, Cognition, and Depressive Symptoms Among Older Mexican Americans American journal of epidemiology, 2019; 188(11): 1944-1952.
- German Christopher A, Sinsheimer Janet S, Zhou Jin, Zhou Hua WiSER: Robust and scalable estimation and inference of within-subject variances from intensive longitudinal data Biometrics, 2021; 13(1): 123.
- Garske Kristina M, Pan David Z, Miao Zong, Bhagat Yash V, Comenho Caroline, Robles Christopher R, Benhammou Jihane N, Alvarez Marcus, Ko Arthur, Ye Chun Jimmie, Pisegna Joseph R, Mohlke Karen L, Sinsheimer Janet S, Laakso Markku, Pajukanta Päivi Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans Nature metabolism, 2019; 1(6): 630-642.
- Landeros Alfonso, Ji Xiang, Lange Kenneth, Stutz Timothy C, Xu Jason, Sehl Mary E, Sinsheimer Janet S An examination of school reopening strategies during the SARS-CoV-2 pandemic PloS one, 2021; 16(5): e0251242.
- Chuang Yu-Hsuan, Paul Kimberly C, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette M, Ritz Beate Genetic variants in nicotinic receptors and smoking cessation in Parkinson’s disease Parkinsonism & related disorders, 2019; 62(6): 57-61.
- Ji Sarah S, German Christopher A, Lange Kenneth, Sinsheimer Janet S, Zhou Hua, Zhou Jin, Sobel Eric M Modern simulation utilities for genetic analysis BMC bioinformatics, 2021; 22(1): 228.
- Landeros Alfonso, Stutz Timothy, Keys Kevin L, Alekseyenko Alexander, Sinsheimer Janet S, Lange Kenneth, Sehl Mary E BioSimulator.jl: Stochastic simulation in Julia Computer methods and programs in biomedicine, 2018; 167(6): 23-35.
- Studwell Courtney M, Kelley Emily G, Kelley Emily G, Sinsheimer Janet S, Palmer Christina G S, LeBlanc Kimberly Family genetic result communication in rare and undiagnosed disease communities: Understanding the practice Journal of genetic counseling, 2021; 30(2): 439-447.
- Lin Liang-Yu, Chun Chang Sunny, O’Hearn Jim, Hui Simon T, Seldin Marcus, Gupta Pritha, Bondar Galyna, Deng Mario, Jauhiainen Raimo, Kuusisto Johanna, Laakso Markku, Sinsheimer Janet S, Deb Arjun, Rau Christoph, Ren Shuxun, Wang Yibin, Lusis Aldons J, Wang Jessica J, Huertas-Vazquez Adriana Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans G3 (Bethesda, Md.), 2018; 8(11): 3499-3506.
- Stutz Timothy C, Landeros Alfonso, Xu Jason, Sinsheimer Janet S, Sehl Mary, Lange Kenneth Stochastic simulation algorithms for Interacting Particle Systems PloS one, 2021; 16(3): e0247046.
- Gilbert Princess S, Wu Jing, Simon Margaret W, Sinsheimer Janet S, Alfaro Michael E Filtering nucleotide sites by phylogenetic signal to noise ratio increases confidence in the Neoaves phylogeny generated from ultraconserved elements Molecular phylogenetics and evolution, 2018; 126(5): 116-128.
- Palmer Christina G S, McConkie-Rosell Allyn, Holm Ingrid A, LeBlanc Kimberly, Sinsheimer Janet S, Briere Lauren C, Dorrani Naghmeh, Herzog Matthew R, Lincoln Sharyn, Schoch Kelly, Spillmann Rebecca C, Brokamp Elly, Brokamp Elly Understanding Adult Participant and Parent Empowerment Prior to Evaluation in the Undiagnosed Diseases Network Journal of genetic counseling, 2018; 27(5): 1087-1101.
- Pan David Z, Garske Kristina M, Alvarez Marcus, Bhagat Yash V, Boocock James, Nikkola Elina, Miao Zong, Raulerson Chelsea K, Cantor Rita M, Civelek Mete, Glastonbury Craig A, Small Kerrin S, Boehnke Michael, Lusis Aldons J, Sinsheimer Janet S, Mohlke Karen L, Laakso Markku, Pajukanta Päivi, Ko Arthur Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS Nature communications, 2018; 9(1): 3472.
- Crandall Carolyn J, Diamant Allison L, Maglione Margaret, Thurston Rebecca C, Sinsheimer Janet Genetic Variation and Hot Flashes: A Systematic Review The Journal of clinical endocrinology and metabolism, 2020; 105(12): e0247046.
- Lake James A, Larsen Joseph, Tran Dan Thy, Sinsheimer Janet S Uncovering the Genomic Origins of Life Genome biology and evolution, 2018; 10(7): 1705-1714.
- Hung Tony K W, Dong Tien S, Chen Zixi, Elashoff David, Sinsheimer Janet S, Jacobs Jonathan P, Lagishetty Venu, Vora Priten, Stains Jean, Mayer Emeran A, Gupta Arpana Understanding the Heterogeneity of Obesity and the Relationship to the Brain-Gut Axis Nutrients, 2020; 12(12): e0247046.
- Paul Kimberly C, Sinsheimer Janet S, Cockburn Myles, Bronstein Jeff M, Bordelon Yvette, Ritz Beate NFE2L2, PPARGC1α, and pesticides and Parkinson’s disease risk and progression Mechanisms of ageing and development, 2018; 173(7): 1-8.
- vonHoldt Bridgett M, Ji Sarah S, Aardema Matthew L, Stahler Daniel R, Udell Monique A R, Sinsheimer Janet S Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome Genome biology and evolution, 2018; 10(6): 1546-1553.
- Levine Andrew J, Soontornniyomkij Virawudh, Masliah Eliezer, Sinsheimer Janet S, Ji Sarah S, Horvath Steve, Singer Elyse J, Kallianpur Asha, Moore David J A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders Journal of neurovirology, 2020; 26(4): 496-508.