Publications

1. Ramanathan G, Zhao Y, Gupta R, Langmo S, Bhetraratana M, Yin F, Driscoll W, Ricks J, Louie A, Stewart JA, Gould TR, Larson TV, Kaufman J, Rosenfeld ME, Yang X, Araujo JA. Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants.. Particle and fibre toxicology, 2024.
2. Castellanos JA, Cornett CG, Gonzalez DH, Li L, Luna K, Middlekauff HR, Gupta R, Jordan MC, Rünger D, Zhu Y, Shao XM, Roos KP, Araujo JA. Electronic cigarettes alter cardiac rhythm and heart rate variability hyperacutely in mice.. Toxicology and applied pharmacology, 2024.
3. Lin Y, Shi X, Qiu X, Jiang X, Liu J, Zhong P, Ge Y, Tseng CH, Zhang JJ, Zhu T, Araujo JA, Zhu Y. Reduction in polycyclic aromatic hydrocarbon exposure in Beijing following China's clean air actions.. Science bulletin, 2024.
4. Chang C, Louie A, Zhou Y, Gupta R, Liang F, Xanthou G, Ereso J, Koletic C, Yang JC, Sedighian F, Lagishetty V, Arias-Jayo N, Altuwayjiri A, Tohidi R, Navab M, Reddy ST, Sioutas C, Hsiai T, Araujo JA, Jacobs JP. Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid.. International journal of molecular sciences, 2024.
5. Bhetraratana M, Orozco LD, Bennett BJ, Luna K, Yang X, Lusis AJ, Araujo JA. Diesel exhaust particle extract elicits an oxPAPC-like transcriptomic profile in macrophages across multiple mouse strains.. Environmental pollution (Barking, Essex : 1987), 2024.
6. Chang C, Gupta R, Sedighian F, Louie A, Gonzalez DM, Le C, Cho JM, Park SK, Castellanos J, Ting TW, Dong TS, Arias-Jayo N, Lagishetty V, Navab M, Reddy S, Sioutas C, Hsiai T, Jacobs JP, Araujo JA. Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models.. Environmental research, 2024.
7. Kelesidis T, Sharma M, Satta S, Tran E, Gupta R, Araujo JA, Middlekauff HR. Ectodomain shedding of proteins important for SARS-CoV-2 pathogenesis in plasma of tobacco cigarette smokers compared to electronic cigarette vapers: a cross-sectional study.. Journal of molecular medicine (Berlin, Germany), 2023.
8. Lin Y, Zhu Y, Qiu X, Lu X, Yin F, Tseng CH, Araujo JA. Passive smoking and urinary oxidative biomarkers: A pilot study of healthy travelers from Los Angeles to Beijing.. International journal of hygiene and environmental health, 2022.
9. Lin Y, Lu X, Qiu X, Yin F, Faull KF, Tseng CH, Zhang JJ, Fiehn O, Zhu T, Araujo JA, Zhu Y. Arachidonic acid metabolism and inflammatory biomarkers associated with exposure to polycyclic aromatic hydrocarbons.. Environmental research, 2022.
10. Lu X, Lin Y, Qiu X, Liu J, Zhu T, Araujo JA, Fiehn O, Zhu Y. Triglyceride profiles are associated with subacute exposure to bisphenol A in healthy young adults.. The Science of the total environment, 2022.
11. Lind L, Araujo JA, Barchowsky A, Belcher S, Berridge BR, Chiamvimonvat N, Chiu WA, Cogliano VJ, Elmore S, Farraj AK, Gomes AV, McHale CM, Meyer-Tamaki KB, Posnack NG, Vargas HM, Yang X, Zeise L, Zhou C, Smith MT. Key Characteristics of Cardiovascular Toxicants.. Environmental health perspectives, 2021.
12. Rezk-Hanna M, Gupta R, Nettle CO, Dobrin D, Cheng CW, Means A, Brecht ML, Tashkin DP, Araujo JA. Differential Effects of Electronic Hookah Vaping and Traditional Combustible Hookah Smoking on Oxidation, Inflammation, and Arterial Stiffness.. Chest, 2021.
13. Gupta R, Lin Y, Luna K, Logue A, Yoon AJ, Haptonstall KP, Moheimani R, Choroomi Y, Nguyen K, Tran E, Zhu Y, Faull KF, Kelesidis T, Gornbein J, Middlekauff HR, Araujo JA. Electronic and Tobacco Cigarettes Alter Polyunsaturated Fatty Acids and Oxidative Biomarkers.. Circulation research, 2021.
14. Lu X, Lin Y, Qiu X, Liu J, Zhu T, Araujo JA, Zhang J, Zhu Y. Metabolomic Changes after Subacute Exposure to Polycyclic Aromatic Hydrocarbons: A Natural Experiment among Healthy Travelers from Los Angeles to Beijing.. Environmental science & technology, 2021.
15. Rezk-Hanna M, Seals DR, Rossman MJ, Gupta R, Nettle CO, Means A, Dobrin D, Cheng CW, Brecht ML, Mosenifar Z, Araujo JA, Benowitz NL. Ascorbic Acid Prevents Vascular Endothelial Dysfunction Induced by Electronic Hookah (Waterpipe) Vaping.. Journal of the American Heart Association, 2021.
16. Lin Y, Gao X, Qiu X, Liu J, Tseng CH, Zhang JJ, Araujo JA, Zhu Y. Urinary carboxylic acid metabolites as possible novel biomarkers of exposures to alkylated polycyclic aromatic hydrocarbons.. Environment international, 2020.
17. Middlekauff HR, William KJ, Su B, Haptonstall K, Araujo JA, Wu X, Kim J, Sallam T. Changes in lipid composition associated with electronic cigarette use.. Journal of translational medicine, 2020.
18. Barnhill LM, Khuansuwan S, Juarez D, Murata H, Araujo JA, Bronstein JM. Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy.. Toxicological sciences : an official journal of the Society of Toxicology, 2020.
19. Lin Y, Qiu X, Liu J, Tseng CH, Allard P, Araujo JA, Zhu Y. Different temporal trends of exposure to Bisphenol A among international travelers between Los Angeles and Beijing.. Environment international, 2020.
20. Lin Y, Ramanathan G, Zhu Y, Yin F, Rea ND, Lu X, Tseng CH, Faull KF, Yoon AJ, Jerrett M, Zhu T, Qiu X, Araujo JA. Pro-Oxidative and Proinflammatory Effects After Traveling From Los Angeles to Beijing: A Biomarker-Based Natural Experiment.. Circulation, 2019.
21. Bhetraratana M, Orozco LD, Hong J, Diamante G, Majid S, Bennett BJ, Ahn IS, Yang X, Lusis AJ, Araujo JA. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies.. Archives of biochemistry and biophysics, 2019.
22. Woodward NC, Crow AL, Zhang Y, Epstein S, Hartiala J, Johnson R, Kocalis H, Saffari A, Sankaranarayanan I, Akbari O, Ramanathan G, Araujo JA, Finch CE, Bouret SG, Sioutas C, Morgan TE, Allayee H. Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice.. Scientific reports, 2019.
23. Zhang M, Nakamura K, Kageyama S, Lawal AO, Gong KW, Bhetraratana M, Fujii T, Sulaiman D, Hirao H, Bolisetty S, Kupiec-Weglinski JW, Araujo JA. Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury.. JCI insight, 2018.
24. Kageyama S, Hirao H, Nakamura K, Ke B, Zhang M, Ito T, Aziz A, Oncel D, Kaldas FM, Busuttil RW, Sosa RA, Reed EF, Araujo JA, Kupiec-Weglinski JW. Recipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside.. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018.
25. Nakamura K, Zhang M, Kageyama S, Ke B, Araujo JA, Kupiec-Weglinski JW. Reply to: "Protective effects of heme oxygenase 1 during ischemia-reperfusion injury: Hepatocytes or non parenchymal cells?". Journal of hepatology, 2018.
26. Middlekauff HR, Araujo JA. Increased Cardiovascular Risk Associated With E-Cigarette Use-Reply.. JAMA cardiology, 2017.
27. Moheimani RS, Bhetraratana M, Peters KM, Yang BK, Yin F, Gornbein J, Araujo JA, Middlekauff HR. Sympathomimetic Effects of Acute E-Cigarette Use: Role of Nicotine and Non-Nicotine Constituents.. Journal of the American Heart Association, 2017.
28. Boas Z, Gupta P, Moheimani RS, Bhetraratana M, Yin F, Peters KM, Gornbein J, Araujo JA, Czernin J, Middlekauff HR. Activation of the "Splenocardiac Axis" by electronic and tobacco cigarettes in otherwise healthy young adults.. Physiological reports, 2017.
29. Nakamura K, Zhang M, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Araujo JA, Kupiec-Weglinski JW. Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury.. Journal of hepatology, 2017.
30. Moheimani RS, Bhetraratana M, Yin F, Peters KM, Gornbein J, Araujo JA, Middlekauff HR. Increased Cardiac Sympathetic Activity and Oxidative Stress in Habitual Electronic Cigarette Users: Implications for Cardiovascular Risk.. JAMA cardiology, 2017.
31. Ramanathan G, Yin F, Speck M, Tseng CH, Brook JR, Silverman F, Urch B, Brook RD, Araujo JA. Effects of urban fine particulate matter and ozone on HDL functionality.. Particle and fibre toxicology, 2016.
32. Lin Y, Qiu X, Yu N, Yang Q, Araujo JA, Zhu Y. Urinary Metabolites of Polycyclic Aromatic Hydrocarbons and the Association with Lipid Peroxidation: A Biomarker-Based Study between Los Angeles and Beijing.. Environmental science & technology, 2016.
33. Lawal A, Zhang M, Dittmar M, Lulla A, Araujo JA. Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals.. Toxicology and applied pharmacology, 2015.
34. Ramanathan G, Araujo JA, Gornbein J, Yin F, Middlekauff HR. Cigarette smoking is associated with dose-dependent adverse effects on paraoxonase activity and fibrinogen in young women.. Inhalation toxicology, 2014.
35. Li R, Navab K, Hough G, Daher N, Zhang M, Mittelstein D, Lee K, Pakbin P, Saffari A, Bhetraratana M, Sulaiman D, Beebe T, Wu L, Jen N, Wine E, Tseng CH, Araujo JA, Fogelman A, Sioutas C, Navab M, Hsiai TK. Effect of exposure to atmospheric ultrafine particles on production of free fatty acids and lipid metabolites in the mouse small intestine.. Environmental health perspectives, 2014.
36. Maiseyeu A, Yang HY, Ramanathan G, Yin F, Bard RL, Morishita M, Dvonch JT, Wang L, Spino C, Mukherjee B, Badgeley MA, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo JA, Brook RD. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function.. Inhalation toxicology, 2014.
37. Miller MR, McLean SG, Duffin R, Lawal AO, Araujo JA, Shaw CA, Mills NL, Donaldson K, Newby DE, Hadoke PW. Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice.. Particle and fibre toxicology, 2013.
38. Breton CV, Yin F, Wang X, Avol E, Gilliland FD, Araujo JA. HDL anti-oxidant function associates with LDL level in young adults.. Atherosclerosis, 2013.
39. Araujo JA. HO-1 and CO: fighters vs sickle cell disease?. Blood, 2013.
40. Li R, Navab M, Pakbin P, Ning Z, Navab K, Hough G, Morgan TE, Finch CE, Araujo JA, Fogelman AM, Sioutas C, Hsiai T. Ambient ultrafine particles alter lipid metabolism and HDL anti-oxidant capacity in LDLR-null mice.. Journal of lipid research, 2013.
41. Yin F, Lawal A, Ricks J, Fox JR, Larson T, Navab M, Fogelman AM, Rosenfeld ME, Araujo JA. Diesel exhaust induces systemic lipid peroxidation and development of dysfunctional pro-oxidant and pro-inflammatory high-density lipoprotein.. Arteriosclerosis, thrombosis, and vascular biology, 2013.
42. Yin F, Ramanathan G, Zhang M, Araujo JA. Prooxidative effects of ambient pollutant chemicals are inhibited by HDL.. Journal of biochemical and molecular toxicology, 2013.
43. Araujo JA, Zhang M, Yin F. Heme oxygenase-1, oxidation, inflammation, and atherosclerosis.. Frontiers in pharmacology, 2012.
44. Romanoski CE, Che N, Yin F, Mai N, Pouldar D, Civelek M, Pan C, Lee S, Vakili L, Yang WP, Kayne P, Mungrue IN, Araujo JA, Berliner JA, Lusis AJ. Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.. Circulation research, 2011.
45. Araujo JA. Are ultrafine particles a risk factor for cardiovascular diseases?. Revista espanola de cardiologia, 2011.
46. Araujo JA. Particulate air pollution, systemic oxidative stress, inflammation, and atherosclerosis.. Air quality, atmosphere, & health, 2010.
47. Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection.. Arteriosclerosis, thrombosis, and vascular biology, 2010.
48. Araujo JA, Nel AE. Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress.. Particle and fibre toxicology, 2009.
49. Campbell A, Araujo JA, Li H, Sioutas C, Kleinman M. Particulate matter induced enhancement of inflammatory markers in the brains of apolipoprotein E knockout mice.. Journal of nanoscience and nanotechnology, 2009.
50. Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ. Copy number variation influences gene expression and metabolic traits in mice.. Human molecular genetics, 2009.
51. Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress.. Circulation research, 2008.
52. Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.. Circulation research, 2007.
53. Ke B, Shen XD, Tsuchihashi S, Gao F, Araujo JA, Busuttil RW, Ritter T, Kupiec-Weglinski JW. Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity.. Human gene therapy, 2007.
54. Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.. Arteriosclerosis, thrombosis, and vascular biology, 2007.
55. Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells.. Genome biology, 2007.
56. Tsuchihashi S, Livhits M, Zhai Y, Busuttil RW, Araujo JA, Kupiec-Weglinski JW. Basal rather than induced heme oxygenase-1 levels are crucial in the antioxidant cytoprotection.. Journal of immunology (Baltimore, Md. : 1950), 2006.
57. Lai DW, Saver JL, Araujo JA, Reidl M, Tobis J. Pericarditis associated with nickel hypersensitivity to the Amplatzer occluder device: a case report.. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2005.
58. Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, Ishikawa K, Iyer S, Buelow R, Busuttil RW, Shih DM, Lusis AJ, Kupiec-Weglinski JW. Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse.. Journal of immunology (Baltimore, Md. : 1950), 2003.