
Ke Sheng
Professor, Radiation Oncology, University of California Los Angeles
200 Medl Plz, Ste B265
CA
Fax Number:
310-983-3603
Affiliations
Member, Physics & Biology in Medicine GPB Home Area
Biography:
Dr. Sheng has a B.S. degree in mechanical engineering and an M.S. degree in astrophysics from the University of Science and Technology of China. In 2004, Dr. Sheng received his Ph.D. from the University of Wisconsin-Madison in medical physics. He is certified by the American Board of Radiology in radiation therapy physics. He was appointed as Assistant Professor and then Associate Professor at the University of Virginia prior to joining UCLA, where he was promoted to tenured full Professor. Dr. Sheng has wide research interests including treatment planning optimization, particle therapy, image reconstruction and processing, radiobiology, and novel radiotherapy instrumentations. He runs an active and productive research group consisting of junior faculty, postdoctoral researchers and graduate students. He is supported by NIH, DOE and industrial partners. He is a fellow of American Association of Physicists in Medicine.
Publications
- Ramesh P, Lyu Q, Gu W, Ruan D, Sheng K. Reformulated McNamara RBE-weighted beam orientation optimization for intensity modulated proton therapy.. Medical physics, 2022.
- Woods KE, Ma TM, Cook KA, Morris ED, Gao Y, Sheng K, Kishan AU, Hegde JV, Felix C, Basehart V, Narahara K, Shen Z, Tenn S, Steinberg ML, Chin RK, Cao M. A Prospective Phase II Study of Automated Non-Coplanar VMAT for Recurrent Head and Neck Cancer: Initial Report of Feasibility, Safety, and Patient-Reported Outcomes.. Cancers, 2022.
- Ma TM, Neylon J, Casado M, Sharma S, Sheng K, Low D, Yang Y, Steinberg ML, Lamb J, Cao M, Kishan AU. Dosimetric impact of interfraction prostate and seminal vesicle volume changes and rotation: A post-hoc analysis of a phase III randomized trial of MRI-guided versus CT-guided stereotactic body radiotherapy.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2021.
- Lao Y, Ruan D, Vassantachart A, Fan Z, Ye JC, Chang EL, Chin R, Kaprealian T, Zada G, Shiroishi MS, Sheng K, Yang W. Voxelwise Prediction of Recurrent High-Grade Glioma via Proximity Estimation-Coupled Multidimensional Support Vector Machine.. International journal of radiation oncology, biology, physics, 2021.
- Lao Y, Cao M, Yang Y, Kishan AU, Yang W, Wang Y, Sheng K. Bladder surface dose modeling in prostate cancer radiotherapy: An analysis of motion-induced variations and the cumulative dose across the treatment.. Medical physics, 2021.
- Pham J, Savjani RR, Gao Y, Cao M, Hu P, Sheng K, Low DA, Steinberg M, Kishan AU, Yang Y. Evaluation of T2-Weighted MRI for Visualization and Sparing of Urethra with MR-Guided Radiation Therapy (MRgRT) On-Board MRI.. Cancers, 2021.
- McKenzie EM, Tong N, Ruan D, Cao M, Chin RK, Sheng K. Using neural networks to extend cropped medical images for deformable registration among images with differing scan extents.. Medical physics, 2021.
- Neylon J, Cook KA, Yang Y, Du D, Sheng K, Chin RK, Kishan AU, Lamb JM, Low DA, Cao M. Clinical assessment of geometric distortion for a 0.35T MR-guided radiotherapy system.. Journal of applied clinical medical physics, 2021.
- Cao M, Gao Y, Yoon SM, Yang Y, Sheng K, Ballas LK, Basehart V, Sachdeva A, Felix C, Low DA, Steinberg ML, Kishan AU. Interfractional Geometric Variations and Dosimetric Benefits of Stereotactic MRI Guided Online Adaptive Radiotherapy (SMART) of Prostate Bed after Radical Prostatectomy: Post-Hoc Analysis of a Phase II Trial.. Cancers, 2021.
- Ma TM, Lamb JM, Casado M, Wang X, Basehart TV, Yang Y, Low D, Sheng K, Agazaryan N, Nickols NG, Cao M, Steinberg ML, Kishan AU. Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial.. BMC cancer, 2021.
- Woods K, Chin RK, Cook KA, Sheng K, Kishan AU, Hegde JV, Tenn S, Steinberg ML, Cao M. Automated Non-Coplanar VMAT for Dose Escalation in Recurrent Head and Neck Cancer Patients.. Cancers, 2021.
- Lao Y, Yu V, Pham A, Wang T, Cui J, Gallogly A, Chang E, Fan Z, Kaprealian T, Yang W, Sheng K. Quantitative Characterization of Tumor Proximity to Stem Cell Niches: Implications on Recurrence and Survival in GBM Patients.. International journal of radiation oncology, biology, physics, 2021.
- Yu VY, Nguyen D, O'Connor D, Ruan D, Kaprealian T, Chin R, Sheng K. Treating Glioblastoma Multiforme (GBM) with super hyperfractionated radiation therapy: Implication of temporal dose fractionation optimization including cancer stem cell dynamics.. PloS one, 2021.
- Neph R, Lyu Q, Huang Y, Yang YM, Sheng K. DeepMC: a deep learning method for efficient Monte Carlo beamlet dose calculation by predictive denoising in magnetic resonance-guided radiotherapy.. Physics in medicine and biology, 2021.
- Lyu Q, Neph R, O'Connor D, Ruan D, Boucher S, Sheng K. ROAD: ROtational direct Aperture optimization with a Decoupled ring-collimator for FLASH radiotherapy.. Physics in medicine and biology, 2021.
- Tong N, Gou S, Chen S, Yao Y, Yang S, Cao M, Kishan A, Sheng K. Multi-task edge-recalibrated network for male pelvic multi-organ segmentation on CT images.. Physics in medicine and biology, 2021.
- Iwamoto KS, Sandstrom RE, Bryan M, Liu Y, Elgart SR, Sheng K, Steinberg ML, McBride WH, Low DA. Weak Magnetic Fields Enhance the Efficacy of Radiation Therapy.. Advances in radiation oncology, 2021.
- Cao Y, Vassantachart A, Ye JC, Yu C, Ruan D, Sheng K, Lao Y, Shen ZL, Balik S, Bian S, Zada G, Shiu A, Chang EL, Yang W. Automatic detection and segmentation of multiple brain metastases on magnetic resonance image using asymmetric UNet architecture.. Physics in medicine and biology, 2021.
- Gou S, Tong N, Qi S, Yang S, Chin R, Sheng K. Self-channel-and-spatial-attention neural network for automated multi-organ segmentation on head and neck CT images.. Physics in medicine and biology, 2020.
- Cao M, Stiehl B, Yu VY, Sheng K, Kishan AU, Chin RK, Yang Y, Ruan D. Analysis of Geometric Performance and Dosimetric Impact of Using Automatic Contour Segmentation for Radiotherapy Planning.. Frontiers in oncology, 2020.
- Hu Q, Yu VY, Yang Y, Hu P, Sheng K, Lee PP, Kishan AU, Raldow AC, O'Connell DP, Woods KE, Cao M. Practical Safety Considerations for Integration of Magnetic Resonance Imaging in Radiation Therapy.. Practical radiation oncology, 2020.
- Gu W, O'Connor D, Ruan D, Zou W, Dong L, Sheng K. Fraction-variant beam orientation optimization for intensity-modulated proton therapy.. Medical physics, 2020.
- Sheng K. Artificial intelligence in radiotherapy: a technological review.. Frontiers of medicine, 2020.
- Gu W, Ruan D, Zou W, Dong L, Sheng K. Linear energy transfer weighted beam orientation optimization for intensity-modulated proton therapy.. Medical physics, 2020.
- Tong N, Gou S, Niu T, Yang S, Sheng K. Self-paced DenseNet with boundary constraint for automated multi-organ segmentation on abdominal CT images.. Physics in medicine and biology, 2020.
- Lao Y, David J, Fan Z, Bian S, Shiu A, Chang EL, Sheng K, Yang W, Tuli R. Quantifying vascular invasion in pancreatic cancer-a contrast CT based method for surgical resectability evaluation.. Physics in medicine and biology, 2020.
- Xue Y, Luo C, Jiang Y, Yang P, Hu X, Zhou Q, Wang J, Hu X, Sheng K, Niu T. Image domain multi-material decomposition using single energy CT.. Physics in medicine and biology, 2020.
- Gu W, Ruan D, Lyu Q, Zou W, Dong L, Sheng K. A novel energy layer optimization framework for spot-scanning proton arc therapy.. Medical physics, 2020.
- Lyu Q, Neph R, Yu VY, Ruan D, Boucher S, Sheng K. Many-isocenter optimization for robotic radiotherapy.. Physics in medicine and biology, 2020.
- McKenzie EM, Santhanam A, Ruan D, O'Connor D, Cao M, Sheng K. Multimodality image registration in the head-and-neck using a deep learning-derived synthetic CT as a bridge.. Medical physics, 2020.
- Shang D, Gu W, Landers A, Woods K, Yu V, Neph R, Tenn S, Sheng K. Technical Note: Robust individual thermoluminescence dosimeter tracking using optical fingerprinting.. Medical physics, 2019.
- Woods K, Nguyen D, Neph R, Ruan D, O'Connor D, Sheng K. A sparse orthogonal collimator for small animal intensity-modulated radiation therapy part I: Planning system development and commissioning.. Medical physics, 2019.
- Woods K, Neph R, Nguyen D, Sheng K. A sparse orthogonal collimator for small animal intensity-modulated radiation therapy. Part II: hardware development and commissioning.. Medical physics, 2019.
- Lyu Q, O'Connor D, Niu T, Sheng K. Image-domain multimaterial decomposition for dual-energy computed tomography with nonconvex sparsity regularization.. Journal of medical imaging (Bellingham, Wash.), 2019.
- Landers A, O'Connor D, Ruan D, Sheng K. Automated 4p radiotherapy treatment planning with evolving knowledge-base.. Medical physics, 2019.
- Jiang Y, Yang C, Yang P, Hu X, Luo C, Xue Y, Xu L, Hu X, Zhang L, Wang J, Sheng K, Niu T. Scatter correction of cone-beam CT using a deep residual convolution neural network (DRCNN).. Physics in medicine and biology, 2019.
- Neph R, Ouyang C, Neylon J, Yang Y, Sheng K. Parallel beamlet dose calculation via beamlet contexts in a distributed multi-GPU framework.. Medical physics, 2019.
- Gu W, Neph R, Ruan D, Zou W, Dong L, Sheng K. Robust beam orientation optimization for intensity-modulated proton therapy.. Medical physics, 2019.
- Jiang Y, Xue Y, Lyu Q, Xu L, Luo C, Yang P, Yang C, Wang J, Hu X, Zhang X, Sheng K, Niu T. Noise Suppression in Image-Domain Multi-Material Decomposition for Dual-Energy CT.. IEEE transactions on bio-medical engineering, 2019.
- Tong N, Gou S, Yang S, Cao M, Sheng K. Shape constrained fully convolutional DenseNet with adversarial training for multiorgan segmentation on head and neck CT and low-field MR images.. Medical physics, 2019.
- Lyu Q, Neph R, Yu VY, Ruan D, Sheng K. Single-arc VMAT optimization for dual-layer MLC.. Physics in medicine and biology, 2019.
- Zhao N, O'Connor D, Basarab A, Ruan D, Sheng K. Motion Compensated Dynamic MRI Reconstruction With Local Affine Optical Flow Estimation.. IEEE transactions on bio-medical engineering, 2019.
- Gu W, Ruan D, O'Connor D, Zou W, Dong L, Tsai MY, Jia X, Sheng K. Robust optimization for intensity-modulated proton therapy with soft spot sensitivity regularization.. Medical physics, 2019.
- Sheng KL, Pridham KJ, Sheng Z, Lamouille S, Varghese RT. Functional Blockade of Small GTPase RAN Inhibits Glioblastoma Cell Viability.. Frontiers in oncology, 2019.
- Tong N, Gou S, Yang S, Ruan D, Sheng K. Fully automatic multi-organ segmentation for head and neck cancer radiotherapy using shape representation model constrained fully convolutional neural networks.. Medical physics, 2018.
- Lyu Q, Yu VY, Ruan D, Neph R, O'Connor D, Sheng K. A novel optimization framework for VMAT with dynamic gantry couch rotation.. Physics in medicine and biology, 2018.
- Han F, Zhou Z, Du D, Gao Y, Rashid S, Cao M, Shaverdian N, Hegde JV, Steinberg M, Lee P, Raldow A, Low DA, Sheng K, Yang Y, Hu P. Respiratory motion-resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK): Initial clinical experience on an MRI-guided radiotherapy system.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018.
- Lyu Q, O'Connor D, Ruan D, Yu V, Nguyen D, Sheng K. VMAT optimization with dynamic collimator rotation.. Medical physics, 2018.
- Lyu Q, Yang C, Gao H, Xue Y, O'Connor D, Niu T, Sheng K. Technical Note: Iterative megavoltage CT (MVCT) reconstruction using block-matching 3D-transform (BM3D) regularization.. Medical physics, 2018.
- Sheng K, Pawlicki T, Cai J. A career path for pure academic medical physicists in radiation oncology should be established.. Medical physics, 2018.
- Sheng K. Response to "in regard to "Tran A, Zhang J, Woods K, Yu V, Nguyen D, Gustafson G, Rosen L, Sheng K. Treatment planning comparison of IMPT, VMAT and 4p radiotherapy for prostate cases"".. Radiation oncology (London, England), 2018.
- Murzin VL, Woods K, Moiseenko V, Karunamuni R, Tringale KR, Seibert TM, Connor MJ, Simpson DR, Sheng K, Hattangadi-Gluth JA. 4π plan optimization for cortical-sparing brain radiotherapy.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018.
- Gu W, O'Connor D, Nguyen D, Yu VY, Ruan D, Dong L, Sheng K. Integrated beam orientation and scanning-spot optimization in intensity-modulated proton therapy for brain and unilateral head and neck tumors.. Medical physics, 2018.
- O'Connor D, Yu V, Nguyen D, Ruan D, Sheng K. Fraction-variant beam orientation optimization for non-coplanar IMRT.. Physics in medicine and biology, 2018.
- Woods K, Lee P, Kaprealian T, Yang I, Sheng K. Cochlea-sparing acoustic neuroma treatment with 4π radiation therapy.. Advances in radiation oncology, 2018.
- Yu VY, Landers A, Woods K, Nguyen D, Cao M, Du D, Chin RK, Sheng K, Kaprealian TB. A Prospective 4p Radiation Therapy Clinical Study in Recurrent High-Grade Glioma Patients.. International journal of radiation oncology, biology, physics, 2018.
- Landers A, Neph R, Scalzo F, Ruan D, Sheng K. Performance Comparison of Knowledge-Based Dose Prediction Techniques Based on Limited Patient Data.. Technology in cancer research & treatment, 2018.
- Nguyen D, O'Connor D, Ruan D, Sheng K. Deterministic direct aperture optimization using multiphase piecewise constant segmentation.. Medical physics, 2017.
- Qi XS, Pajonk F, McCloskey S, Low DA, Kupelian P, Steinberg M, Sheng K. Radioresistance of the breast tumor is highly correlated to its level of cancer stem cell and its clinical implication for breast irradiation.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017.
- Johnstone CD, Lindsay P, Graves EE, Wong E, Perez JR, Poirier Y, Ben-Bouchta Y, Kanesalingam T, Chen H, Rubinstein AE, Sheng K, Bazalova-Carter M. Multi-institutional MicroCT image comparison of image-guided small animal irradiators.. Physics in medicine and biology, 2017.
- Tran A, Woods K, Nguyen D, Yu VY, Niu T, Cao M, Lee P, Sheng K. Predicting liver SBRT eligibility and plan quality for VMAT and 4p plans.. Radiation oncology (London, England), 2017.
- Han F, Zhou Z, Cao M, Yang Y, Sheng K, Hu P. Respiratory motion-resolved, self-gated 4D-MRI using rotating cartesian k-space (ROCK).. Medical physics, 2017.
- Shaverdian N, Yang Y, Hu P, Hart S, Sheng K, Lamb J, Cao M, Agazaryan N, Thomas D, Steinberg M, Low DA, Lee P. Feasibility evaluation of diffusion-weighted imaging using an integrated MRI-radiotherapy system for response assessment to neoadjuvant therapy in rectal cancer.. The British journal of radiology, 2017.
- Tran A, Zhang J, Woods K, Yu V, Nguyen D, Gustafson G, Rosen L, Sheng K. Treatment planning comparison of IMPT, VMAT and 4p radiotherapy for prostate cases.. Radiation oncology (London, England), 2017.
- Xu R, Yang HN, Li YQ, Wang QF, Guo AH, Ayiti A, Chen XC, Gong R, Banu G, Jian LD, Gao Y, Sheng K, Maimti Y. Association of coronary artery calcium with bone mineral density in postmenopausal women.. Coronary artery disease, 2016.
- Nguyen D, Thomas D, Cao M, O'Connor D, Lamb J, Sheng K. Computerized triplet beam orientation optimization for MRI-guided Co-60 radiotherapy.. Medical physics, 2016.
- Nguyen D, Lyu Q, Ruan D, O'Connor D, Low DA, Sheng K. A comprehensive formulation for volumetric modulated arc therapy planning.. Medical physics, 2016.
- Gou S, Lee P, Hu P, Rwigema JC, Sheng K. Feasibility of automated 3-dimensional magnetic resonance imaging pancreas segmentation.. Advances in radiation oncology, 2016.
- Yang Y, Cao M, Sheng K, Gao Y, Chen A, Kamrava M, Lee P, Agazaryan N, Lamb J, Thomas D, Low D, Hu P. Longitudinal diffusion MRI for treatment response assessment: Preliminary experience using an MRI-guided tri-cobalt 60 radiotherapy system.. Medical physics, 2016.
- Hasse K, Neylon J, Sheng K, Santhanam AP. Systematic feasibility analysis of a quantitative elasticity estimation for breast anatomy using supine/prone patient postures.. Medical physics, 2016.
- Jin J, McKenzie E, Fan Z, Tuli R, Deng Z, Pang J, Fraass B, Li D, Sandler H, Yang G, Sheng K, Gou S, Yang W. Nonlocal Means Denoising of Self-Gated and k-Space Sorted 4-Dimensional Magnetic Resonance Imaging Using Block-Matching and 3-Dimensional Filtering: Implications for Pancreatic Tumor Registration and Segmentation.. International journal of radiation oncology, biology, physics, 2016.
- Nguyen D, Ruan D, O'Connor D, Woods K, Low DA, Boucher S, Sheng K. A novel software and conceptual design of the hardware platform for intensity modulated radiation therapy.. Medical physics, 2016.
- Merna C, Rwigema JC, Cao M, Wang PC, Kishan AU, Michailian A, Lamb J, Sheng K, Agazaryan N, Low DA, Kupelian P, Steinberg ML, Lee P. A treatment planning comparison between modulated tri-cobalt-60 teletherapy and linear accelerator-based stereotactic body radiotherapy for central early-stage non-small cell lung cancer.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2016.
- Yang Y, Cao M, Kaprealian T, Sheng K, Gao Y, Han F, Gomez C, Santhanam A, Tenn S, Agazaryan N, Low DA, Hu P. Accuracy of UTE-MRI-based patient setup for brain cancer radiation therapy.. Medical physics, 2016.
- Woods K, Nguyen D, Tran A, Yu VY, Cao M, Niu T, Lee P, Sheng K. Viability of Non-Coplanar VMAT for Liver SBRT as Compared to Coplanar VMAT and Beam Orientation Optimized 4p IMRT.. Advances in radiation oncology, 2016.
- Yu VY, Tran A, Nguyen D, Cao M, Ruan D, Low DA, Sheng K. The development and verification of a highly accurate collision prediction model for automated noncoplanar plan delivery.. Medical physics, 2015.
- Wu P, Sun X, Hu H, Mao T, Zhao W, Sheng K, Cheung AA, Niu T. Iterative CT shading correction with no prior information.. Physics in medicine and biology, 2015.
- Qi XS, Santhanam A, Neylon J, Min Y, Armstrong T, Sheng K, Staton RJ, Pukala J, Pham A, Low DA, Lee SP, Steinberg M, Manon R, Chen AM, Kupelian P. Near Real-Time Assessment of Anatomic and Dosimetric Variations for Head and Neck Radiation Therapy via Graphics Processing Unit-based Dose Deformation Framework.. International journal of radiation oncology, biology, physics, 2015.
- Nguyen D, O'Connor D, Yu VY, Ruan D, Cao M, Low DA, Sheng K. Dose domain regularization of MLC leaf patterns for highly complex IMRT plans.. Medical physics, 2015.
- Gou S, Wang Y, Wu J, Lee P, Sheng K. Lung dynamic MRI deblurring using low-rank decomposition and dictionary learning.. Medical physics, 2015.
- Kishan AU, Cao M, Wang PC, Mikaeilian AG, Tenn S, Rwigema JM, Sheng K, Low DA, Kupelian PA, Steinberg ML, Lee P. Feasibility of magnetic resonance imaging-guided liver stereotactic body radiation therapy: A comparison between modulated tri-cobalt-60 teletherapy and linear accelerator-based intensity modulated radiation therapy.. Practical radiation oncology, 2015.
- Yu VY, Nguyen D, Pajonk F, Kupelian P, Kaprealian T, Selch M, Low DA, Sheng K. Incorporating cancer stem cells in radiation therapy treatment response modeling and the implication in glioblastoma multiforme treatment resistance.. International journal of radiation oncology, biology, physics, 2015.
- Sheng K, Shepard DM, Orton CG. Point/Counterpoint. Noncoplanar beams improve dosimetry quality for extracranial intensity modulated radiotherapy and should be used more extensively.. Medical physics, 2015.
- Rwigema JC, Nguyen D, Heron DE, Chen AM, Lee P, Wang PC, Vargo JA, Low DA, Huq MS, Tenn S, Steinberg ML, Kupelian P, Sheng K. 4p noncoplanar stereotactic body radiation therapy for head-and-neck cancer: potential to improve tumor control and late toxicity.. International journal of radiation oncology, biology, physics, 2014.
- Nguyen D, Rwigema JC, Yu VY, Kaprealian T, Kupelian P, Selch M, Lee P, Low DA, Sheng K. Feasibility of extreme dose escalation for glioblastoma multiforme using 4p radiotherapy.. Radiation oncology (London, England), 2014.
- Sheng K, Gou S, Wu J, Qi SX. Denoised and texture enhanced MVCT to improve soft tissue conspicuity.. Medical physics, 2014.
- Kishan AU, Wang PC, Sheng K, Yu V, Ruan D, Cao M, Tenn S, Low DA, Lee P. Correlation of Clinical and Dosimetric Parameters With Radiographic Lung Injury Following Stereotactic Body Radiotherapy.. Technology in cancer research & treatment, 2014.
- Mata J, Sheng K, Hagspiel K, Ruppert K, Sylvester P, Mugler J, Fernandes C, Guan S, Larner J, Read P. Pulmonary toxicity in a rabbit model of stereotactic lung radiation therapy: efficacy of a radioprotector.. Experimental lung research, 2014.
- Dong P, Yu V, Nguyen D, Demarco J, Woods K, Boucher S, Low DA, Sheng K. Feasibility of using intermediate x-ray energies for highly conformal extracranial radiotherapy.. Medical physics, 2014.
- Sarma M, Hu P, Rapacchi S, Ennis D, Thomas A, Lee P, Kupelian P, Sheng K. Accelerating dynamic magnetic resonance imaging (MRI) for lung tumor tracking based on low-rank decomposition in the spatial-temporal domain: a feasibility study based on simulation and preliminary prospective undersampled MRI.. International journal of radiation oncology, biology, physics, 2014.
- Nguyen D, Dong P, Long T, Ruan D, Low DA, Romeijn E, Sheng K. Integral dose investigation of non-coplanar treatment beam geometries in radiotherapy.. Medical physics, 2014.
- Dong P, Nguyen D, Ruan D, King C, Long T, Romeijn E, Low DA, Kupelian P, Steinberg M, Yang Y, Sheng K. Feasibility of prostate robotic radiation therapy on conventional C-arm linacs.. Practical radiation oncology, 2013.
- Thomas MA, Nagarajan R, Huda A, Margolis D, Sarma MK, Sheng K, Reiter RE, Raman SS. Multidimensional MR spectroscopic imaging of prostate cancer in vivo.. NMR in biomedicine, 2013.
- Dong P, Lee P, Ruan D, Long T, Romeijn E, Low DA, Kupelian P, Abraham J, Yang Y, Sheng K. 4p noncoplanar stereotactic body radiation therapy for centrally located or larger lung tumors.. International journal of radiation oncology, biology, physics, 2013.
- Santhanam AP, Dou T, Neylon J, Min Y, Kupelian A, Sheng K, Ennis D, Rolland J, Low D, Kupelian P. Multi-scale, multi-modal image integration for image-guided clinical interventions in the head and neck anatomy.. Studies in health technology and informatics, 2013.
- Dong P, Lee P, Ruan D, Long T, Romeijn E, Yang Y, Low D, Kupelian P, Sheng K. 4p non-coplanar liver SBRT: a novel delivery technique.. International journal of radiation oncology, biology, physics, 2012.
- Dunlap NE, Yang W, McIntosh A, Sheng K, Benedict SH, Read PW, Larner JM. Computed tomography-based anatomic assessment overestimates local tumor recurrence in patients with mass-like consolidation after stereotactic body radiotherapy for early-stage non-small cell lung cancer.. International journal of radiation oncology, biology, physics, 2012.
- Nagarajan R, Margolis D, Raman S, Sarma MK, Sheng K, King CR, Verma G, Sayre J, Reiter RE, Thomas MA. MR spectroscopic imaging and diffusion-weighted imaging of prostate cancer with Gleason scores.. Journal of magnetic resonance imaging : JMRI, 2012.
- Chen Q, Westerly D, Fang Z, Sheng K, Chen Y. TomoTherapy MLC verification using exit detector data.. Medical physics, 2012.
- Nagarajan R, Margolis D, Raman S, Sheng K, King C, Reiter R, Thomas MA. Correlation of Gleason scores with diffusion-weighted imaging findings of prostate cancer.. Advances in urology, 2011.
- Baisden JM, Sheehan J, Reish AG, McIntosh AF, Sheng K, Read PW, Benedict SH, Larner JM. Helical tomotherapy simultaneous integrated boost provides a dosimetric advantage in the treatment of primary intracranial tumors.. Neurological research, 2011.
- Yang W, Jones R, Lu W, Geesey C, Benedict S, Read P, Larner J, Sheng K. Feasibility of non-coplanar tomotherapy for lung cancer stereotactic body radiation therapy.. Technology in cancer research & treatment, 2011.
- Jones R, Yang W, Read P, Sheng K. Radiation therapy of post-mastectomy patients with positive nodes using fixed beam tomotherapy.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011.
- Cai J, McLawhorn R, Altes TA, de Lange E, Read PW, Larner JM, Benedict SH, Sheng K. Helical tomotherapy planning for lung cancer based on ventilation magnetic resonance imaging.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2011.
- Shoushtari A, Saylor D, Kerr KL, Sheng K, Thomas C, Jameson M, Reibel J, Shonka D, Levine P, Read P. Outcomes of patients with head-and-neck cancer of unknown primary origin treated with intensity-modulated radiotherapy.. International journal of radiation oncology, biology, physics, 2011.
- Sheng K, Jones R, Yang W, Saraiya S, Schneider B, Chen Q, Sobering G, Olivera G, Read P. 3D dose verification using tomotherapy CT detector array.. International journal of radiation oncology, biology, physics, 2011.
- Libby B, Sheng K, McLawhorn R, McIntosh A, Van Ausdal RG, Martof A, Read P. Use of megavoltage computed tomography with image registration for high-dose rate treatment planning of an oral tongue cancer using a custom oral mold applicator with embedded lead shielding.. Brachytherapy, 2011.
- Yang W, Jones R, Read P, Benedict S, Sheng K. Standardized evaluation of simultaneous integrated boost plans on volumetric modulated arc therapy.. Physics in medicine and biology, 2010.
- Wang L, Yang W, Read P, Larner J, Sheng K. Tumor cell apoptosis induced by nanoparticle conjugate in combination with radiation therapy.. Nanotechnology, 2010.
- Cai J, Yue J, McLawhorn R, Yang W, Wijesooriya K, Dunlap NE, Sheng K, Yin FF, Benedict SH. Dosimetric comparison of 6 MV and 15 MV single arc rapidarc to helical TomoTherapy for the treatment of pancreatic cancer.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2010.
- Cai J, McLawhorn R, Read PW, Larner JM, Yin FF, Benedict SH, Sheng K. Effects of breathing variation on gating window internal target volume in respiratory gated radiation therapy.. Medical physics, 2010.
- Shoushtari A, Meeneghan M, Sheng K, Moskaluk CA, Thomas CY, Reibel JF, Levine PA, Jameson MJ, Keene K, Read PW. Intensity-modulated radiotherapy outcomes for oropharyngeal squamous cell carcinoma patients stratified by p16 status.. Cancer, 2010.
- Dunlap NE, Larner JM, Read PW, Kozower BD, Lau CL, Sheng K, Jones DR. Size matters: a comparison of T1 and T2 peripheral non-small-cell lung cancers treated with stereotactic body radiation therapy (SBRT).. The Journal of thoracic and cardiovascular surgery, 2010.
- Rao M, Yang W, Chen F, Sheng K, Ye J, Mehta V, Shepard D, Cao D. Comparison of Elekta VMAT with helical tomotherapy and fixed field IMRT: plan quality, delivery efficiency and accuracy.. Medical physics, 2010.
- Dunlap N, McIntosh A, Sheng K, Yang W, Turner B, Shoushtari A, Sheehan J, Jones DR, Lu W, Ruchala K, Olivera G, Parnell D, Larner JL, Benedict SH, Read PW. Helical tomotherapy-based STAT stereotactic body radiation therapy: Dosimetric evaluation for a real-time SBRT treatment planning and delivery program.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2010.
- McIntosh A, Dunlap N, Sheng K, Geezey C, Turner B, Blackhall L, Weiss G, Lappinen E, Larner JM, Read PW. Helical tomotherapy-based STAT RT: Dosimetric evaluation for clinical implementation of a rapid radiation palliation program.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2009.
- Yang W, Wang L, Larner J, Read P, Benedict S, Sheng K. Tumor cell survival dependence on helical tomotherapy, continuous arc and segmented dose delivery.. Physics in medicine and biology, 2009.
- Zhong X, Meyer CH, Schlesinger DJ, Sheehan JP, Epstein FH, Larner JM, Benedict SH, Read PW, Sheng K, Cai J. Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI.. Medical physics, 2009.
- Cai J, Sheng K, Benedict SH, Read PW, Larner JM, Mugler JP, de Lange EE, Cates GD, Miller GW. Dynamic MRI of grid-tagged hyperpolarized helium-3 for the assessment of lung motion during breathing.. International journal of radiation oncology, biology, physics, 2009.
- Dunlap NE, Cai J, Biedermann GB, Yang W, Benedict SH, Sheng K, Schefter TE, Kavanagh BD, Larner JM. Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy.. International journal of radiation oncology, biology, physics, 2009.
- Yang W, Van Ausdal R, Read P, Larner J, Benedict S, Sheng K. The implication of non-cyclic intrafractional longitudinal motion in SBRT by TomoTherapy.. Physics in medicine and biology, 2009.
- Cai J, Mata JF, Orton MD, Hagspiel KD, Mugler JP, Larner JM, Sheng K, Read PW. A rabbit irradiation platform for outcome assessment of lung stereotactic radiosurgery.. International journal of radiation oncology, biology, physics, 2009.
- Cai J, Read PW, Larner JM, Jones DR, Benedict SH, Sheng K. Reproducibility of interfraction lung motion probability distribution function using dynamic MRI: statistical analysis.. International journal of radiation oncology, biology, physics, 2008.
- Yang W, Read PW, Mi J, Baisden JM, Reardon KA, Larner JM, Helmke BP, Sheng K. Semiconductor nanoparticles as energy mediators for photosensitizer-enhanced radiotherapy.. International journal of radiation oncology, biology, physics, 2008.
- Cai J, Read PW, Sheng K. The effect of respiratory motion variability and tumor size on the accuracy of average intensity projection from four-dimensional computed tomography: an investigation based on dynamic MRI.. Medical physics, 2008.
- McIntosh A, Read PW, Khandelwal SR, Arthur DW, Turner AB, Ruchala KJ, Olivera GH, Jeswani S, Sheng K. Evaluation of coplanar partial left breast irradiation using tomotherapy-based topotherapy.. International journal of radiation oncology, biology, physics, 2008.
- Sheng K, Chow J, Hunter G, Larner J, Read P. Is daily CT image guidance necessary for nasal cavity and nasopharyngeal radiotherapy: an investigation based on helical tomotherapy.. Journal of applied clinical medical physics, 2008.
- Cai J, Read PW, Baisden JM, Larner JM, Benedict SH, Sheng K. Estimation of error in maximal intensity projection-based internal target volume of lung tumors: a simulation and comparison study using dynamic magnetic resonance imaging.. International journal of radiation oncology, biology, physics, 2007.
- Cai J, Sheng K, Sheehan JP, Benedict SH, Larner JM, Read PW. Evaluation of thoracic spinal cord motion using dynamic MRI.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007.
- Baisden JM, Romney DA, Reish AG, Cai J, Sheng K, Jones DR, Benedict SH, Read PW, Larner JM. Dose as a function of lung volume and planned treatment volume in helical tomotherapy intensity-modulated radiation therapy-based stereotactic body radiation therapy for small lung tumors.. International journal of radiation oncology, biology, physics, 2007.
- Cai J, Miller GW, Altes TA, Read PW, Benedict SH, de Lange EE, Cates GD, Brookeman JR, Mugler JP, Sheng K. Direct measurement of lung motion using hyperpolarized helium-3 MR tagging.. International journal of radiation oncology, biology, physics, 2007.
- Sheng K, Molloy JA, Larner JM, Read PW. A dosimetric comparison of non-coplanar IMRT versus Helical Tomotherapy for nasal cavity and paranasal sinus cancer.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007.
- Cai J, Read PW, Altes TA, Molloy JA, Brookeman JR, Sheng K. Evaluation of the reproducibility of lung motion probability distribution function (PDF) using dynamic MRI.. Physics in medicine and biology, 2006.
- Kanagaki B, Read PW, Molloy JA, Larner JM, Sheng K. A motion phantom study on helical tomotherapy: the dosimetric impacts of delivery technique and motion.. Physics in medicine and biology, 2006.
- Sheng K, Cai J, Brookeman J, Molloy J, Christopher J, Read P. A computer simulated phantom study of tomotherapy dose optimization based on probability density functions (PDF) and potential errors caused by low reproducibility of PDF.. Medical physics, 2006.
- Baisden JM, Reish AG, Sheng K, Larner JM, Kavanagh BD, Read PW. Dose as a function of liver volume and planning target volume in helical tomotherapy, intensity-modulated radiation therapy-based stereotactic body radiation therapy for hepatic metastasis.. International journal of radiation oncology, biology, physics, 2006.
- Sheng K, Molloy JA, Read PW. Intensity-modulated radiation therapy (IMRT) dosimetry of the head and neck: a comparison of treatment plans using linear accelerator-based IMRT and helical tomotherapy.. International journal of radiation oncology, biology, physics, 2006.
- Sheng K, Jeraj R, Shaw R, Mackie TR, Paliwal BR. Imaging dose management using multi-resolution in CT-guided radiation therapy.. Physics in medicine and biology, 2005.