Otoniel Martinez-Maza

Otoniel Martinez-Maza

(310) 825-2542

Laboratory Address:
UCLA AIDS Institute
615 Charles E. Young Drive South
BSRB 157
Los Angeles, CA 90095

Mailing Address:
BOX 951740, 153 BSRB
Los Angeles, CA 90095

Office Address:
615 Charles F. Young Drive South
BSRB 173
mail code: 736322
Los Angeles, CA 90095


Member, CTSI, Immunity, Microbes & Molecular Pathogenesis GPB Home Area, Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC) , Microbiology, Immunology & Molecular Genetics

Research Interests

We are interested in better understanding the role of immune dysfunction in the genesis and growth of human cancer. Current work is focusing on better defining the role of HIV infection-associated immune dysfunction in the development and growth of AIDS-associated cancers. Currently, much of our work is directed at determining how immune system factors associated with B cell hyperactivation, including the up-regulation of the expression of activation-induced cytidine deaminase (AID), and virus (EBV, HIV) infection, contribute to the molecular lesions that result in the genesis of B cell lymphoma.


Dr. Martinez-Maza received his Ph.D. in Microbiology and Immunology from UCLA in 1981, going on to do postdoctoral work at the Karolinska Institute (Stockholm), Pasteur Institute (Paris), and at UCLA. He has been a faculty member at UCLA since 1988, most recently serving as Professor of Obstetrics & Gynecology (Vice Chair for Basic Research) and Microbiology, Immunology & Molecular Genetics in the David Geffen School of Medicine at UCLA, as well as in Epidemiology in the UCLA Fielding School of Public Health. Martinez-Maza also is a member of the UCLA AIDS Institute, where his laboratory is physically located, as well as the Jonsson Comprehensive Cancer Center. He is actively involved in several national and international multi-center studies, serving on the Executive Committees of the Multicenter AIDS Cohort Study and the AIDS Malignancies Consortium, and participating in Interlymph, an international consortium of researchers with an interest in the epidemiology and pathogenesis of lymphoma. In addition to this, he is on the external steering committee for the AIDS Cancer Specimen Resource, is a member of the advisory council for the California HIV Research Program and of the Human Stem Cell Research Advisory Committee, California Department of Health Services


A selected list of publications: