Publications

1. Jeyachandran AV, Zaiss AK, Chakravarty N, Singh S, Delgado Y, Paravastu R, Satheeshkumar N, Gerald E, Jeysankar A, Thomas J, Fuller L, Lee N, Taylor C, Joshi S, Parcells M, French SW, Date A, Bouhaddou M, Garcia G, Kumar A, Damoiseaux R, Arumugaswami V. Drug screen reveals new potent host-targeted antivirals against Mpox virus.. bioRxiv : the preprint server for biology, 2025.
2. Betz UAK, Garces R, Beier N, Lindemann S, Wolff KC, Riva L, Kirkpatrick MG, Gebara-Lamb A, McNamara CW, Damoiseaux R, Gomperts BN, Arumugaswami V, Strand M, Gwon Y, Elofsson M, Evander M. Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas.. Viruses, 2025.
3. Petcherski A, Tingley BM, Martin A, Adams S, Brownstein AJ, Steinberg RA, Shabane B, Ngo J, Osto C, Garcia G, Veliova M, Arumugaswami V, Colby AH, Shirihai OS, Grinstaff MW. Endolysosome-targeted nanoparticle delivery of antiviral therapy for coronavirus infections.. Life science alliance, 2025.
4. Sen C, Rickabaugh TM, Jeyachandran AV, Yuen C, Ghannam M, Durra A, Aziz A, Castillo K, Garcia G, Purkayastha A, Han B, Boulton FW, Chekler E, Garces R, Wolff KC, Riva L, Kirkpatrick MG, Gebara-Lamb A, McNamara CW, Betz UAK, Arumugaswami V, Damoiseaux R, Gomperts BN. Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2.. Respiratory research, 2025.
5. Abt ER, Lam AK, Noguchi M, Rashid K, McLaughlin J, Teng PL, Tran W, Cheng D, Nesterenko PA, Mao Z, Creech AL, Burton Sojo G, Jeyachandran AV, Tam YK, Henley JE, Comai L, Pardi N, Arumugaswami V, Witte ON, Radu CG, Wu TT. Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire.. Proceedings of the National Academy of Sciences of the United States of America, 2024.
6. Qin Y, Cui Q, Sun G, Chao J, Wang C, Chen X, Ye P, Zhou T, Jeyachandran AV, Sun O, Liu W, Yao S, Palmer C, Liu X, Arumugaswami V, Chan WC, Wang X, Shi Y. Developing enhanced immunotherapy using NKG2A knockout human pluripotent stem cell-derived NK cells.. Cell reports, 2024.
7. Chakravarty N, Hemani D, Paravastu R, Ahmad Z, Palani SN, Arumugaswami V, Kumar A. Mpox Virus and its ocular surface manifestations.. The ocular surface, 2024.
8. Takano KA, Wong AAL, Brown R, Situ K, Chua BA, Abu AE, Pham TT, Reyes GC, Ramachandran S, Kamata M, Li MMH, Wu TT, Rao DS, Arumugaswami V, Dorshkind K, Cole S, Morizono K. Envelope protein-specific B cell receptors direct lentiviral vector tropism in vivo.. Molecular therapy : the journal of the American Society of Gene Therapy, 2024.
9. Hasani-Sadrabadi MM, Majedi FS, Zarubova J, Thauland TJ, Arumugaswami V, Hsiai TK, Bouchard LS, Butte MJ, Li S. Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells.. ACS nano, 2024.
10. Singh S, Wright RE, Giri S, Arumugaswami V, Kumar A. Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus-induced ocular pathology.. iScience, 2024.
11. Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.. Communications biology, 2023.
12. Cui Q, Jeyachandran AV, Garcia G, Qin C, Zhou Y, Zhang M, Wang C, Sun G, Liu W, Zhou T, Feng L, Palmer C, Li Z, Aziz A, Gomperts BN, Feng P, Arumugaswami V, Shi Y. The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles.. MedComm, 2023.
13. Garcia G, Chakravarty N, Paiola S, Urena E, Gyani P, Tse C, French SW, Danielpour M, Breunig JJ, Nathanson DA, Arumugaswami V. Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus.. Cells, 2023.
14. Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses.. bioRxiv : the preprint server for biology, 2023.
15. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.. Cell reports. Medicine, 2023.
16. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.. Nature communications, 2023.
17. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses.. bioRxiv : the preprint server for biology, 2023.
18. Cambou MC, Liu CM, Mok T, Fajardo-Martinez V, Paiola SG, Ibarrondo FJ, Kerin T, Fuller T, Tobin NH, Garcia G, Bhattacharya D, Aldrovandi GM, Arumugaswami V, Foo SS, Jung JU, Vasconcelos Z, Brasil P, Brendolin M, Yang OO, Rao R, Nielsen-Saines K. Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy.. The Journal of infectious diseases, 2023.
19. Contreras D, Garcia G, Jones MK, Martinez LE, Jayakarunakaran A, Gangalapudi V, Tang J, Wu Y, Zhao JJ, Chen Z, Ramaiah A, Tsui I, Kumar A, Nielsen-Saines K, Wang S, Arumugaswami V. Differential Susceptibility of Fetal Retinal Pigment Epithelial Cells, hiPSC- Retinal Stem Cells, and Retinal Organoids to Zika Virus Infection.. Viruses, 2023.
20. Garcia G, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response.. PLoS biology, 2022.
21. Chauhan D, Chakravarty N, Jeyachandran AV, Jayakarunakaran A, Sinha S, Mishra R, Arumugaswami V, Ramaiah A. In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics.. Viruses, 2022.
22. Garcia G, Chakravarty N, Abu AE, Jeyachandran AV, Takano KA, Brown R, Morizono K, Arumugaswami V. Replication-Deficient Zika Vector-Based Vaccine Provides Maternal and Fetal Protection in Mouse Model.. Microbiology spectrum, 2022.
23. Petcherski A, Sharma M, Satta S, Daskou M, Vasilopoulos H, Hugo C, Ritou E, Dillon BJ, Fung E, Garcia G, Scafoglio C, Purkayastha A, Gomperts BN, Fishbein GA, Arumugaswami V, Liesa M, Shirihai OS, Kelesidis T. Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models.. bioRxiv : the preprint server for biology, 2022.
24. Arumugaperumal A, Sudalaimani DK, Arumugaswami V, Sivasubramaniam S. Draft Genome Sequence of the Earthworm Eudrilus eugeniae.. Current genomics, 2022.
25. Paul S, Balakrishnan S, Arumugaperumal A, Lathakumari S, Syamala SS, Vijayan V, Durairaj SCJ, Arumugaswami V, Sivasubramaniam S. Importance of clitellar tissue in the regeneration ability of earthworm Eudrilus eugeniae.. Functional & integrative genomics, 2022.
26. Garcia G, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V. Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response.. bioRxiv : the preprint server for biology, 2022.
27. Li YR, Dunn ZS, Garcia G, Carmona C, Zhou Y, Lee D, Yu J, Huang J, Kim JT, Arumugaswami V, Wang P, Yang L. Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention.. Stem cell research & therapy, 2022.
28. Paul S, Dinesh Kumar SM, Syamala SS, Balakrishnan S, Vijayan V, Arumugaswami V, Sudhakar S. Identification, tissue specific expression analysis and functional characterization of arrestin gene (ARRDC) in the earthworm Eudrilus eugeniae: a molecular hypothesis behind worm photoreception.. Molecular biology reports, 2022.
29. Ibrahim AG, Ciullo A, Li C, Garcia G, Peck K, Miyamoto K, Arumugaswami V, Marbán E. Engineered extracellular vesicles antagonize SARS-CoV-2 infection by inhibiting mTOR signaling.. Biomaterials and biosystems, 2022.
30. Cui Q, Garcia G, Zhang M, Wang C, Li H, Zhou T, Sun G, Arumugaswami V, Shi Y. Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection.. iScience, 2021.
31. Wu B, Ramaiah A, Garcia G, Hasiakos S, Arumugaswami V, Srikanth S. ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling.. Journal of immunology (Baltimore, Md. : 1950), 2021.
32. Chakravarty N, Senthilnathan T, Paiola S, Gyani P, Castillo Cario S, Urena E, Jeysankar A, Jeysankar P, Ignatius Irudayam J, Natesan Subramanian S, Lavretsky H, Joshi S, Garcia G, Ramaiah A, Arumugaswami V. Neurological pathophysiology of SARS-CoV-2 and pandemic potential RNA viruses: a comparative analysis.. FEBS letters, 2021.
33. Foo SS, Cambou MC, Mok T, Fajardo VM, Jung KL, Fuller T, Chen W, Kerin T, Mei J, Bhattacharya D, Choi Y, Wu X, Xia T, Shin WJ, Cranston J, Aldrovandi G, Tobin N, Contreras D, Ibarrondo FJ, Yang O, Yang S, Garner O, Cortado R, Bryson Y, Janzen C, Ghosh S, Devaskar S, Asilnejad B, Moreira ME, Vasconcelos Z, Soni PR, Gibson LC, Brasil P, Comhair SAA, Arumugaswami V, Erzurum SC, Rao R, Jung JU, Nielsen-Saines K. The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2.. Cell reports. Medicine, 2021.
34. Luu AP, Yao Z, Ramachandran S, Azzopardi SA, Miles LA, Schneider WM, Hoffmann HH, Bozzacco L, Garcia G, Gong D, Damoiseaux R, Tang H, Morizono K, Rudin CM, Sun R, Arumugaswami V, Poirier JT, MacDonald MR, Rice CM, Li MMH. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.. Viruses, 2021.
35. Liu X, Verma A, Garcia G, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition.. Proceedings of the National Academy of Sciences of the United States of America, 2021.
36. Singh S, Garcia G, Shah R, Kramerov AA, Wright RE, Spektor TM, Ljubimov AV, Arumugaswami V, Kumar A. SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response.. The ocular surface, 2021.
37. Sun G, Cui Q, Garcia G, Wang C, Zhang M, Arumugaswami V, Riggs AD, Shi Y. Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses.. Scientific reports, 2021.
38. Li Y, Garcia G, Arumugaswami V, Guo F. Structure-based design of antisense oligonucleotides that inhibit SARS-CoV-2 replication.. bioRxiv : the preprint server for biology, 2021.
39. Chen F, Shi Q, Pei F, Vogt A, Porritt RA, Garcia G, Gomez AC, Cheng MH, Schurdak ME, Liu B, Chan SY, Arumugaswami V, Stern AM, Taylor DL, Arditi M, Bahar I. A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection.. Molecular systems biology, 2021.
40. Liu X, Verma A, Garcia G, Ramage H, Myers RL, Lucas A, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition.. medRxiv : the preprint server for health sciences, 2021.
41. Shaharuddin SH, Wang V, Santos RS, Gross A, Wang Y, Jawanda H, Zhang Y, Hasan W, Garcia G, Arumugaswami V, Sareen D. Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells.. Frontiers in cellular and infection microbiology, 2021.
42. Song DH, Garcia G, Situ K, Chua BA, Hong MLO, Do EA, Ramirez CM, Harui A, Arumugaswami V, Morizono K. Development of a blocker of the universal phosphatidylserine- and phosphatidylethanolamine-dependent viral entry pathways.. Virology, 2021.
43. Wu B, Ramaiah A, Garcia G, Gwack Y, Arumugaswami V, Srikanth S. ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling.. bioRxiv : the preprint server for biology, 2021.
44. Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro.. Structure (London, England : 1993), 2021.
45. Mulay A, Konda B, Garcia G, Yao C, Beil S, Villalba JM, Koziol C, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.. Cell reports, 2021.
46. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.. Nature communications, 2021.
47. Garcia G, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.. Cell reports, 2021.
48. Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity.. JCI insight, 2021.
49. Shah R, Amador C, Tormanen K, Ghiam S, Saghizadeh M, Arumugaswami V, Kumar A, Kramerov AA, Ljubimov AV. Systemic diseases and the cornea.. Experimental eye research, 2021.
50. Wang C, Zhang M, Garcia G, Tian E, Cui Q, Chen X, Sun G, Wang J, Arumugaswami V, Shi Y. ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response.. Cell stem cell, 2021.
51. Paul S, Balakrishnan S, Arumugaperumal A, Lathakumari S, Syamala SS, Arumugaswami V, Sivasubramaniam S. The transcriptome of anterior regeneration in earthworm Eudrilus eugeniae.. Molecular biology reports, 2020.
52. Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro.. bioRxiv : the preprint server for biology, 2020.
53. Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.. Cell stem cell, 2020.
54. Chen Z, Garcia G, Arumugaswami V, Wirz RE. Cold atmospheric plasma for SARS-CoV-2 inactivation.. Physics of fluids (Woodbury, N.Y. : 1994), 2020.
55. Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response.. bioRxiv : the preprint server for biology, 2020.
56. Sharma A, Garcia G, Wang Y, Plummer JT, Morizono K, Arumugaswami V, Svendsen CN. Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection.. Cell reports. Medicine, 2020.
57. Mulay A, Konda B, Garcia G, Yao C, Beil S, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.. bioRxiv : the preprint server for biology, 2020.
58. Sharma A, Garcia G, Arumugaswami V, Svendsen CN. Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection.. bioRxiv : the preprint server for biology, 2020.
59. Martínez LE, Garcia G, Contreras D, Gong D, Sun R, Arumugaswami V. Zika Virus Mucosal Infection Provides Protective Immunity.. Journal of virology, 2020.
60. Singh S, Singh PK, Suhail H, Arumugaswami V, Pellett PE, Giri S, Kumar A. AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis.. Journal of immunology (Baltimore, Md. : 1950), 2020.
61. Garcia G, Paul S, Beshara S, Ramanujan VK, Ramaiah A, Nielsen-Saines K, Li MMH, French SW, Morizono K, Kumar A, Arumugaswami V. Hippo Signaling Pathway Has a Critical Role in Zika Virus Replication and in the Pathogenesis of Neuroinflammation.. The American journal of pathology, 2020.
62. Thaker SK, Chapa T, Garcia G, Gong D, Schmid EW, Arumugaswami V, Sun R, Christofk HR. Differential Metabolic Reprogramming by Zika Virus Promotes Cell Death in Human versus Mosquito Cells.. Cell metabolism, 2019.
63. Zin AA, Tsui I, Rossetto JD, Gaw SL, Neves LM, Zin OA, Haefeli L, Barros Silveira Filho JC, Adachi K, Vinicius da Silva Pone M, Pone SM, Molleri N, Pereira JP, Belfort R, Arumugaswami V, Vasconcelos Z, Brasil P, Nielsen-Saines K, Lopes Moreira ME. Visual function in infants with antenatal Zika virus exposure.. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2018.
64. Tsui I, Moreira MEL, Rossetto JD, Vasconcelos Z, Gaw SL, Neves LM, Zin OA, Haefeli L, Silveira Filho JCB, Gomes SC, Adachi K, Pone MVDS, Pone SM, Pereira JP, Belfort R, Arumugaswami V, Brasil P, Nielsen-Saines K, Zin AA. Eye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure.. Pediatrics, 2018.
65. Singh PK, Khatri I, Jha A, Pretto CD, Spindler KR, Arumugaswami V, Giri S, Kumar A, Bhasin MK. Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium.. Scientific reports, 2018.
66. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. HSP70 Copurifies with Zika Virus Particles.. Virology, 2018.
67. Lu NT, Liu NM, Patel D, Vu JQ, Liu L, Kim CY, Cho P, Khachatoorian R, Patel N, Magyar CE, Ganapathy E, Arumugaswami V, Dasgupta A, French SW. Oncoprotein Stathmin Modulates Sensitivity to Apoptosis in Hepatocellular Carcinoma Cells During Hepatitis C Viral Replication.. Journal of cell death, 2018.
68. Gong D, Zhang TH, Zhao D, Du Y, Chapa TJ, Shi Y, Wang L, Contreras D, Zeng G, Shi PY, Wu TT, Arumugaswami V, Sun R. High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells.. iScience, 2018.
69. Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M. Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis.. Human molecular genetics, 2017.
70. Subramanian ER, Gopi Daisy N, Sudalaimani DK, Ramamoorthy K, Balakrishnan S, Selvan Christyraj JD, Arumugaswami V, Sivasubramaniam S. Function of translationally controlled tumor protein (TCTP) in Eudrilus eugeniae regeneration.. PloS one, 2017.
71. Ramaiah A, Dai L, Contreras D, Sinha S, Sun R, Arumugaswami V. Comparative analysis of protein evolution in the genome of pre-epidemic and epidemic Zika virus.. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2017.
72. Qi H, Chu V, Wu NC, Chen Z, Truong S, Brar G, Su SY, Du Y, Arumugaswami V, Olson CA, Chen SH, Lin CY, Wu TT, Sun R. Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein.. Proceedings of the National Academy of Sciences of the United States of America, 2017.
73. Talavera-Adame D, Woolcott OO, Ignatius-Irudayam J, Arumugaswami V, Geller DH, Dafoe DC. Erratum to: Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells.. Diabetologia, 2016.
74. Talavera-Adame D, Woolcott OO, Ignatius-Irudayam J, Arumugaswami V, Geller DH, Dafoe DC. Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells.. Diabetologia, 2016.
75. Contreras D, Arumugaswami V. Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons.. Journal of visualized experiments : JoVE, 2016.
76. Gopi Daisy N, Subramanian ER, Selvan Christyraj JD, Sudalai Mani DK, Selvan Christyraj JR, Ramamoorthy K, Arumugaswami V, Sivasubramaniam S. Studies on regeneration of central nervous system and social ability of the earthworm Eudrilus eugeniae.. Invertebrate neuroscience : IN, 2016.
77. Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.. International journal of antimicrobial agents, 2016.
78. Ramaiah A, Arumugaswami V. Ebolavirus evolves in human to minimize the detection by immune cells by accumulating adaptive mutations.. Virusdisease, 2016.
79. Ignatius Irudayam J, Contreras D, Spurka L, Ren S, Kanagavel V, Ramaiah A, Annamalai A, French SW, Klein AS, Funari V, Arumugaswami V. Profile of Inflammation-associated genes during Hepatic Differentiation of Human Pluripotent Stem Cells.. Data in brief, 2015.
80. Irudayam JI, Contreras D, Spurka L, Subramanian A, Allen J, Ren S, Kanagavel V, Nguyen Q, Ramaiah A, Ramamoorthy K, French SW, Klein AS, Funari V, Arumugaswami V. Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection.. Stem cell research, 2015.
81. Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN. Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells.. Stem cells translational medicine, 2015.
82. Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A.. Virology, 2014.
83. Remenyi R, Qi H, Su SY, Chen Z, Wu NC, Arumugaswami V, Truong S, Chu V, Stokelman T, Lo HH, Olson CA, Wu TT, Chen SH, Lin CY, Sun R. A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins.. mBio, 2014.
84. Kurtovic S, Ng TT, Gupta A, Arumugaswami V, Chaiboonma KL, Aminzadeh MA, Makkar R, Dafoe DC, Talavera-Adame D. Leptin enhances endothelial cell differentiation and angiogenesis in murine embryonic stem cells.. Microvascular research, 2014.
85. Ren S, Contreras D, Arumugaswami V. A protocol for analyzing hepatitis C virus replication.. Journal of visualized experiments : JoVE, 2014.
86. Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.. Virology, 2014.
87. Dolan PT, Zhang C, Khadka S, Arumugaswami V, Vangeloff AD, Heaton NS, Sahasrabudhe S, Randall G, Sun R, LaCount DJ. Identification and comparative analysis of hepatitis C virus-host cell protein interactions.. Molecular bioSystems, 2013.
88. Talavera-Adame D, Gupta A, Kurtovic S, Chaiboonma KL, Arumugaswami V, Dafoe DC. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation.. Stem cells and development, 2013.
89. Lassmann B, Arumugaswami V, Chew KW, Lewis MJ. A new system to measure and compare hepatitis C virus replication capacity using full-length, replication competent viruses.. Journal of virological methods, 2013.
90. Chu D, Ren S, Hu S, Wang WG, Subramanian A, Contreras D, Kanagavel V, Chung E, Ko J, Amirtham Jacob Appadorai RS, Sinha S, Jalali Z, Hardy DW, French SW, Arumugaswami V. Systematic analysis of enhancer and critical cis-acting RNA elements in the protein-encoding region of the hepatitis C virus genome.. Journal of virology, 2013.
91. Suhane S, Kanzaki H, Arumugaswami V, Murali R, Ramanujan VK. Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells.. Biology open, 2013.
92. Khachatoorian R, Arumugaswami V, Raychaudhuri S, Yeh GK, Maloney EM, Wang J, Dasgupta A, French SW. Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle.. Virology, 2012.
93. Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW. A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production.. Hepatology (Baltimore, Md.), 2012.
94. Noh CW, Cho HJ, Kang HR, Jin HY, Lee S, Deng H, Wu TT, Arumugaswami V, Sun R, Song MJ. The virion-associated open reading frame 49 of murine gammaherpesvirus 68 promotes viral replication both in vitro and in vivo as a derepressor of RTA.. Journal of virology, 2011.
95. Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW. The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.. Hepatology (Baltimore, Md.), 2009.
96. Arumugaswami V, Kumar PM, Konjufca V, Dienglewicz RL, Reddy SM, Parcells MS. Latency of Marek's disease virus (MDV) in a reticuloendotheliosis virus-transformed T-cell line. I: uptake and structure of the latent MDV genome.. Avian diseases, 2009.
97. Arumugaswami V, Kumar PM, Konjufca V, Dienglewicz RL, Reddy SM, Parcells MS. Latency of Marek's disease virus (MDV) in a reticuloendotheliosis virus-transformed T-cell line. II: expression of the latent MDV genome.. Avian diseases, 2009.
98. Gong D, Qi J, Arumugaswami V, Sun R, Deng H. Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus 68.. Virology, 2009.
99. Arumugaswami V, Sitapara R, Hwang S, Song MJ, Ho TN, Su NQ, Sue EY, Kanagavel V, Xing F, Zhang X, Zhao M, Deng H, Wu TT, Kanagavel S, Zhang L, Dandekar S, Papp J, Sun R. High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genome.. Journal of virology, 2008.
100. Arumugaswami V, Remenyi R, Kanagavel V, Sue EY, Ngoc Ho T, Liu C, Fontanes V, Dasgupta A, Sun R. High-resolution functional profiling of hepatitis C virus genome.. PLoS pathogens, 2008.
101. Sanchez DJ, Miranda D, Arumugaswami V, Hwang S, Singer AE, Senaati A, Shahangian A, Song MJ, Sun R, Cheng G. A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon.. Journal of virology, 2007.
102. Arumugaswami V, Wu TT, Martinez-Guzman D, Jia Q, Deng H, Reyes N, Sun R. ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus.. Journal of virology, 2006.
103. Santin ER, Shamblin CE, Prigge JT, Arumugaswami V, Dienglewicz RL, Parcells MS. Examination of the effect of a naturally occurring mutation in glycoprotein L on Marek's disease virus pathogenesis.. Avian diseases, 2006.
104. Anobile JM, Arumugaswami V, Downs D, Czymmek K, Parcells M, Schmidt CJ. Nuclear localization and dynamic properties of the Marek's disease virus oncogene products Meq and Meq/vIL8.. Journal of virology, 2006.
105. Shamblin CE, Greene N, Arumugaswami V, Dienglewicz RL, Parcells MS. Comparative analysis of Marek's disease virus (MDV) glycoprotein-, lytic antigen pp38- and transformation antigen Meq-encoding genes: association of meq mutations with MDVs of high virulence.. Veterinary microbiology, 2004.
106. Parcells MS, Arumugaswami V, Prigge JT, Pandya K, Dienglewicz RL. Marek's disease virus reactivation from latency: changes in gene expression at the origin of replication.. Poultry science, 2003.