Publications

1. Wang L, Shang J, Weng S, Aliyari SR, Ji C, Cheng G, Wu A. Genomic annotation and molecular evolution of monkeypox virus outbreak in 2022.. Journal of medical virology, 2022.
2. Wang L, Zhou HY, Li JY, Cheng YX, Zhang S, Aliyari S, Wu A, Cheng G. Potential intervariant and intravariant recombination of Delta and Omicron variants.. Journal of medical virology, 2022.
3. Zhang S, Wang J, Wang L, Aliyari S, Cheng G. SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1.. Cellular & molecular immunology, 2022.
4. Aliyari SR, Quanquin N, Pernet O, Zhang S, Wang L, Cheng G. The Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2.. Pathogens (Basel, Switzerland), 2022.
5. Aliyari SR, Ghaffari AA, Pernet O, Parvatiyar K, Wang Y, Gerami H, Tong AJ, Vergnes L, Takallou A, Zhang A, Wei X, Chilin LD, Wu Y, Semenkovich CF, Reue K, Smale ST, Lee B, Cheng G. Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2.. Acta pharmaceutica Sinica. B, 2022.
6. Zhang S, Wang L, Cheng G. The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies.. Molecular therapy : the journal of the American Society of Gene Therapy, 2022.
7. Wang L, Cheng G. Sequence analysis of the emerging SARS-CoV-2 variant Omicron in South Africa.. Journal of medical virology, 2021.
8. López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, White SA, Silva AJ. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications.. Science advances, 2021.
9. Zhang S, Wang J, Cheng G. Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1.. Proceedings of the National Academy of Sciences of the United States of America, 2021.
10. Quanquin NM, Barres LG, Aliyari SR, Day NT, Gerami H, Fisher SJ, Kakuru A, Kamya MR, Havlir DV, Feeney M, Dorsey G, Cheng G, Gaw SL. Gravidity-dependent associations between interferon response and birth weight in placental malaria.. Malaria journal, 2020.
11. Chapon M, Parvatiyar K, Aliyari SR, Zhao JS, Cheng G. Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction.. Journal of virology, 2019.
12. Li C, Zu S, Deng YQ, Li D, Parvatiyar K, Quanquin N, Shang J, Sun N, Su J, Liu Z, Wang M, Aliyari SR, Li XF, Wu A, Ma F, Shi Y, Nielsevn-Saines K, Jung JU, Qin FX, Qin CF, Cheng G. Azithromycin Protects against Zika virus Infection by Upregulating virus-induced Type I and III Interferon Responses.. Antimicrobial agents and chemotherapy, 2019.
13. Nielsen-Saines K, Brasil P, Kerin T, Vasconcelos Z, Gabaglia CR, Damasceno L, Pone M, Abreu de Carvalho LM, Pone SM, Zin AA, Tsui I, Salles TRS, da Cunha DC, Costa RP, Malacarne J, Reis AB, Hasue RH, Aizawa CYP, Genovesi FF, Einspieler C, Marschik PB, Pereira JP, Gaw SL, Adachi K, Cherry JD, Xu Z, Cheng G, Moreira ME. Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children.. Nature medicine, 2019.
14. Tao CY, Shang J, Chen T, Yu D, Jiang YM, Liu D, Cheng GY, Xiao J, Zhao ZZ. Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis.. Medicine, 2019.
15. Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.. Radiation research, 2019.
16. He L, Cheng GS, Zhang YS, He XM, Wang XY, Du YJ. Transcatheter Closure of Perimembranous Ventricular Septal Defects in Children using a Wire-Drifting Technique.. Clinics (Sao Paulo, Brazil), 2018.
17. Parvatiyar K, Pindado J, Dev A, Aliyari SR, Zaver SA, Gerami H, Chapon M, Ghaffari AA, Dhingra A, Cheng G. A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling.. Nature communications, 2018.
18. Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.. Cell reports, 2017.
19. Su Y, Wu L, Mu G, Wang Q, Yang B, Cheng G, Kuang H. 9,19-Cycloartenol glycoside G3 from Cimicifuga simplex regulates immune responses by modulating Th17/Treg ratio.. Bioorganic & medicinal chemistry, 2017.
20. Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.. PloS one, 2017.
21. Dong S, Zhan ZY, Cao HY, Wu C, Bian YQ, Li JY, Cheng GH, Liu P, Sun MY. Urinary metabolomics analysis identifies key biomarkers of different stages of nonalcoholic fatty liver disease.. World journal of gastroenterology, 2017.
22. Wang L, Liu SY, Chen HW, Xu J, Chapon M, Zhang T, Zhou F, Wang YE, Quanquin N, Wang G, Tian X, He Z, Liu L, Yu W, Sanchez DJ, Liang Y, Jiang T, Modlin R, Bloom BR, Li Q, Deng JC, Zhou P, Qin FX, Cheng G. Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets.. Cell host & microbe, 2017.
23. Quanquin N, Wang L, Cheng G. Potential for treatment and a Zika virus vaccine.. Current opinion in pediatrics, 2017.
24. Boxx GM, Cheng G. The Roles of Type I Interferon in Bacterial Infection.. Cell host & microbe, 2016.
25. Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons.. PLoS pathogens, 2016.
26. Wang L, Valderramos SG, Wu A, Ouyang S, Li C, Brasil P, Bonaldo M, Coates T, Nielsen-Saines K, Jiang T, Aliyari R, Cheng G. From Mosquitos to Humans: Genetic Evolution of Zika Virus.. Cell host & microbe, 2016.
27. Wang L, Wu A, Wang YE, Quanquin N, Li C, Wang J, Chen HW, Liu S, Liu P, Zhang H, Qin FX, Jiang T, Cheng G. Functional Genomics Reveals Linkers Critical for Influenza Virus Polymerase.. Journal of virology, 2015.
28. Teles RMB, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa MT, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy.. The Journal of investigative dermatology, 2015.
29. Ma F, Li B, Liu SY, Iyer SS, Yu Y, Wu A, Cheng G. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.. Journal of immunology (Baltimore, Md. : 1950), 2015.
30. Ma F, Li B, Yu Y, Iyer SS, Sun M, Cheng G. Positive feedback regulation of type I interferon by the interferon-stimulated gene STING.. EMBO reports, 2015.
31. Schaue D, Micewicz ED, Ratikan JA, Xie MW, Cheng G, McBride WH. Radiation and inflammation.. Seminars in radiation oncology, 2015.
32. Reichardt AD, Pindado J, Zaver SA, Cheng G. TRAF protein function in noncanonical NF-κB signaling.. Methods in molecular biology (Clifton, N.J.), 2015.
33. Ma F, Liu SY, Razani B, Arora N, Li B, Kagechika H, Tontonoz P, Núñez V, Ricote M, Cheng G. Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon.. Nature communications, 2014.
34. Li JY, Cao HY, Liu P, Cheng GH, Sun MY. Glycyrrhizic acid in the treatment of liver diseases: literature review.. BioMed research international, 2014.
35. Zhang N, Cheng GY, Liu XZ, Zhang FJ. Expression of Bcl-2 and NF-κB in brain tissue after acute renal ischemia-reperfusion in rats.. Asian Pacific journal of tropical medicine, 2014.
36. Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, Brooks DG, Jung ME, Colicelli J, Damoiseaux R, Bradley KA. Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.. Proceedings of the National Academy of Sciences of the United States of America, 2013.
37. Kamo N, Ke B, Ghaffari AA, Shen XD, Busuttil RW, Cheng G, Kupiec-Weglinski JW. ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury.. Hepatology (Baltimore, Md.), 2013.
38. Wilson EB, Yamada DH, Elsaesser H, Herskovitz J, Deng J, Cheng G, Aronow BJ, Karp CL, Brooks DG. Blockade of chronic type I interferon signaling to control persistent LCMV infection.. Science (New York, N.Y.), 2013.
39. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses.. Science (New York, N.Y.), 2013.
40. Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.. Immunity, 2012.
41. Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.. PLoS pathogens, 2012.
42. Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.. Nature immunology, 2012.
43. Huang S, Yu C, Cheng G, Chen Y. Detection of single influenza viral RNA in cells using a polymeric sequence probe.. Analytical chemistry, 2012.
44. Tian X, Xu F, Lung WY, Meyerson C, Ghaffari AA, Cheng G, Deng JC. Poly I:C enhances susceptibility to secondary pulmonary infections by gram-positive bacteria.. PloS one, 2012.
45. Liu SY, Guo JY, Zhang L, Liu ZS, Zheng ZH, Cheng GY, Gao GM, Zhang X, Liu GZ, Zeng XF. [Incidence of metabolic syndrome in systemic lupus erythematosus and its influence by glucocorticoids].. Zhonghua nei ke za zhi, 2012.
46. Ding X, Sanchez DJ, Shahangian A, Al-Shyoukh I, Cheng G, Ho CM. Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity.. International journal of nanomedicine, 2012.
47. Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy.. Nature medicine, 2012.
48. Liu SY, Sanchez DJ, Aliyari R, Lu S, Cheng G. Systematic identification of type I and type II interferon-induced antiviral factors.. Proceedings of the National Academy of Sciences of the United States of America, 2012.
49. Razani B, Reichardt AD, Cheng G. Non-canonical NF-κB signaling activation and regulation: principles and perspectives.. Immunological reviews, 2011.
50. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages.. Science translational medicine, 2011.
51. Liu Y, Tian X, Leitner WW, Aldridge ME, Zheng J, Yu Z, Restifo NP, Weiss R, Scheiblhofer S, Xie C, Sun R, Cheng G, Zeng G. Polymeric structure and host Toll-like receptor 4 dictate immunogenicity of NY-ESO-1 antigen in vivo.. The Journal of biological chemistry, 2011.
52. Koon HW, Shih DQ, Chen J, Bakirtzi K, Hing TC, Law I, Ho S, Ichikawa R, Zhao D, Xu H, Gallo R, Dempsey P, Cheng G, Targan SR, Pothoulakis C. Cathelicidin signaling via the Toll-like receptor protects against colitis in mice.. Gastroenterology, 2011.
53. Parvatiyar K, Cheng G. NOD so fast: NLRX1 puts the brake on inflammation.. Immunity, 2011.
54. Ghaffari AA, Chow EK, Iyer SS, Deng JC, Cheng G. Polyinosinic-polycytidylic acid suppresses acetaminophen-induced hepatotoxicity independent of type I interferons and toll-like receptor 3.. Hepatology (Baltimore, Md.), 2011.
55. Pietras EM, Miller LS, Johnson CT, O'Connell RM, Dempsey PW, Cheng G. A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge.. Cell research, 2011.
56. Tricker E, Arvand A, Kwan R, Chen GY, Gallagher E, Cheng G. Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1.. PloS one, 2011.
57. Schopf E, Liu Y, Deng JC, Yang S, Cheng G, Chen Y. tuberculosis detection via rolling circle amplification.. Analytical methods : advancing methods and applications, 2011.
58. Dev A, Iyer S, Razani B, Cheng G. NF-κB and innate immunity.. Current topics in microbiology and immunology, 2011.
59. Liu SY, Sanchez DJ, Cheng G. New developments in the induction and antiviral effectors of type I interferon.. Current opinion in immunology, 2010.
60. Iyer SS, Ghaffari AA, Cheng G. Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages.. Journal of immunology (Baltimore, Md. : 1950), 2010.
61. Razani B, Cheng G. NF-kappaB: much learned, much to learn.. Science signaling, 2010.
62. Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF, Loo JA, Cheng G. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation.. Science signaling, 2010.
63. Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.. The Journal of clinical investigation, 2010.
64. Chin AI, Miyahira AK, Covarrubias A, Teague J, Guo B, Dempsey PW, Cheng G. Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance.. Cancer research, 2010.
65. Wang Y, Zhang P, Liu Y, Cheng G. TRAF-mediated regulation of immune and inflammatory responses.. Science China. Life sciences, 2010.
66. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. Divergence of macrophage phagocytic and antimicrobial programs in leprosy.. Cell host & microbe, 2009.
67. Shahangian A, Chow EK, Tian X, Kang JR, Ghaffari A, Liu SY, Belperio JA, Cheng G, Deng JC. Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice.. The Journal of clinical investigation, 2009.
68. Liu PT, Schenk M, Walker VP, Dempsey PW, Kanchanapoomi M, Wheelwright M, Vazirnia A, Zhang X, Steinmeyer A, Zügel U, Hollis BW, Cheng G, Modlin RL. Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses.. PloS one, 2009.
69. Hwang S, Kim KS, Flano E, Wu TT, Tong LM, Park AN, Song MJ, Sanchez DJ, O'Connell RM, Cheng G, Sun R. Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response.. Cell host & microbe, 2009.
70. Miyahira AK, Shahangian A, Hwang S, Sun R, Cheng G. TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections.. Journal of immunology (Baltimore, Md. : 1950), 2009.
71. Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.. Nature immunology, 2008.
72. Pietras EM, Cheng G. A New TRADDition in intracellular antiviral signaling.. Science signaling, 2008.
73. Tricker E, Cheng G. With a little help from my friends: modulation of phagocytosis through TLR activation.. Cell research, 2008.
74. Guo B, Chang EY, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.. The Journal of clinical investigation, 2008.
75. Pietras EM, Cheng G. New tricks for old NODs.. Genome biology, 2008.
76. Zhai Y, Qiao B, Shen XD, Gao F, Busuttil RW, Cheng G, Platt JL, Volk HD, Kupiec-Weglinski JW. Evidence for the pivotal role of endogenous toll-like receptor 4 ligands in liver ischemia and reperfusion injury.. Transplantation, 2008.
77. Velázquez P, Wei B, McPherson M, Mendoza LM, Nguyen SL, Turovskaya O, Kronenberg M, Huang TT, Schrage M, Lobato LN, Fujiwara D, Brewer S, Arditi M, Cheng G, Sartor RB, Newberry RD, Braun J. Villous B cells of the small intestine are specialized for invariant NK T cell dependence.. Journal of immunology (Baltimore, Md. : 1950), 2008.
78. Zarnegar B, Yamazaki S, He JQ, Cheng G. Control of canonical NF-kappaB activation through the NIK-IKK complex pathway.. Proceedings of the National Academy of Sciences of the United States of America, 2008.
79. Chow EK, Pierstorff E, Cheng G, Ho D. Copolymeric nanofilm platform for controlled and localized therapeutic delivery.. ACS nano, 2008.
80. Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells.. Journal of immunology (Baltimore, Md. : 1950), 2007.
81. Sanchez DJ, Miranda D, Arumugaswami V, Hwang S, Singer AE, Senaati A, Shahangian A, Song MJ, Sun R, Cheng G. A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon.. Journal of virology, 2007.
82. Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.. Journal of immunology (Baltimore, Md. : 1950), 2007.
83. Oganesyan G, Saha SK, Pietras EM, Guo B, Miyahira AK, Zarnegar B, Cheng G. IRF3-dependent type I interferon response in B cells regulates CpG-mediated antibody production.. The Journal of biological chemistry, 2007.
84. Chang EY, Guo B, Doyle SE, Cheng G. Cutting edge: involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production.. Journal of immunology (Baltimore, Md. : 1950), 2007.
85. Guo B, Cheng G. Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK.. The Journal of biological chemistry, 2007.
86. Chow EK, Razani B, Cheng G. Innate immune system regulation of nuclear hormone receptors in metabolic diseases.. Journal of leukocyte biology, 2007.
87. He JQ, Oganesyan G, Saha SK, Zarnegar B, Cheng G. TRAF3 and its biological function.. Advances in experimental medicine and biology, 2007.
88. He JQ, Saha SK, Kang JR, Zarnegar B, Cheng G. Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway.. The Journal of biological chemistry, 2006.
89. Chow EK, Castrillo A, Shahangian A, Pei L, O'Connell RM, Modlin RL, Tontonoz P, Cheng G. A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections.. The Journal of experimental medicine, 2006.
90. He JQ, Zarnegar B, Oganesyan G, Saha SK, Yamazaki S, Doyle SE, Dempsey PW, Cheng G. Rescue of TRAF3-null mice by p100 NF-kappa B deficiency.. The Journal of experimental medicine, 2006.
91. Deng JC, Cheng G, Newstead MW, Zeng X, Kobayashi K, Flavell RA, Standiford TJ. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M.. The Journal of clinical investigation, 2006.
92. Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif.. The EMBO journal, 2006.
93. Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response.. Journal of immunology (Baltimore, Md. : 1950), 2006.
94. Saha SK, Cheng G. TRAF3: a new regulator of type I interferons.. Cell cycle (Georgetown, Tex.), 2006.
95. Miller LS, O'Connell RM, Gutierrez MA, Pietras EM, Shahangian A, Gross CE, Thirumala A, Cheung AL, Cheng G, Modlin RL. MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus.. Immunity, 2006.
96. Pietras EM, Saha SK, Cheng G. The interferon response to bacterial and viral infections.. Journal of endotoxin research, 2006.
97. Chow EK, O'connell RM, Schilling S, Wang XF, Fu XY, Cheng G. TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk.. The EMBO journal, 2005.
98. Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, Perry A, Cheng G. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response.. Nature, 2005.
99. Liu ZS, Cheng GY, Li HJ, Liu SZ, Yao LN, Li JC. [Protective effects of rosiglitazone on hepatotoxicity in hepatocytes cultured with cyclosporine A].. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005.
100. Shen XD, Ke B, Zhai Y, Gao F, Busuttil RW, Cheng G, Kupiec-Weglinski JW. Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury.. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005.
101. Perry AK, Chen G, Zheng D, Tang H, Cheng G. The host type I interferon response to viral and bacterial infections.. Cell research, 2005.
102. Liu B, Yang R, Wong KA, Getman C, Stein N, Teitell MA, Cheng G, Wu H, Shuai K. Negative regulation of NF-kappaB signaling by PIAS1.. Molecular and cellular biology, 2005.
103. Jazirehi AR, Huerta-Yepez S, Cheng G, Bonavida B. Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis.. Cancer research, 2005.
104. Zhai Y, Shen XD, O'Connell R, Gao F, Lassman C, Busuttil RW, Cheng G, Kupiec-Weglinski JW. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway.. Journal of immunology (Baltimore, Md. : 1950), 2004.
105. Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. LXR-dependent gene expression is important for macrophage survival and the innate immune response.. Cell, 2004.
106. O'Connell RM, Saha SK, Vaidya SA, Bruhn KW, Miranda GA, Zarnegar B, Perry AK, Nguyen BO, Lane TF, Taniguchi T, Miller JF, Cheng G. Type I interferon production enhances susceptibility to Listeria monocytogenes infection.. The Journal of experimental medicine, 2004.
107. Huerta-Yepez S, Vega M, Jazirehi A, Garban H, Hongo F, Cheng G, Bonavida B. Nitric oxide sensitizes prostate carcinoma cell lines to TRAIL-mediated apoptosis via inactivation of NF-kappa B and inhibition of Bcl-xl expression.. Oncogene, 2004.
108. Perry AK, Chow EK, Goodnough JB, Yeh WC, Cheng G. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection.. The Journal of experimental medicine, 2004.
109. Zarnegar B, He JQ, Oganesyan G, Hoffmann A, Baltimore D, Cheng G. Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways.. Proceedings of the National Academy of Sciences of the United States of America, 2004.
110. Doyle SE, O'Connell RM, Miranda GA, Vaidya SA, Chow EK, Liu PT, Suzuki S, Suzuki N, Modlin RL, Yeh WC, Lane TF, Cheng G. Toll-like receptors induce a phagocytic gene program through p38.. The Journal of experimental medicine, 2003.
111. Dadgostar H, Doyle SE, Shahangian A, Garcia DE, Cheng G. T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1).. FEBS letters, 2003.
112. Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism.. Molecular cell, 2003.
113. Brown HJ, Song MJ, Deng H, Wu TT, Cheng G, Sun R. NF-kappaB inhibits gammaherpesvirus lytic replication.. Journal of virology, 2003.
114. Vaidya SA, Cheng G. Toll-like receptors and innate antiviral responses.. Current opinion in immunology, 2003.
115. Dempsey PW, Doyle SE, He JQ, Cheng G. The signaling adaptors and pathways activated by TNF superfamily.. Cytokine & growth factor reviews, 2003.
116. Ronni T, Agarwal V, Haykinson M, Haberland ME, Cheng G, Smale ST. Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets.. Molecular and cellular biology, 2003.
117. Doyle SE, O'Connell R, Vaidya SA, Chow EK, Yee K, Cheng G. Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4.. Journal of immunology (Baltimore, Md. : 1950), 2003.
118. Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, Cheng G. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses.. Nature, 2002.
119. Dadgostar H, Zarnegar B, Hoffmann A, Qin XF, Truong U, Rao G, Baltimore D, Cheng G. Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes.. Proceedings of the National Academy of Sciences of the United States of America, 2002.