Brent L. Fogel*

Brent Linden Fogel

Professor-in-Residence, Neurology, University of California Los Angeles

Professor-in-Residence, Human Genetics, University of California Los Angeles

695 Charles E. Young Drive South, Gonda Room 6554A
Los Angeles, CA 90095

Websites

Laboratory

Clinic

Research Interests

  • Neurogenetics
  • Genomics of Neurological Disease
  • Genetic Diagnostics
  • Neurodevelopment
  • Regulation of gene expression
  • Gene therapy
  • Bioinformatics
  • Systems biology
  • Molecular genetics

Biography

Dr. Brent Fogel obtained a Ph.D. in Microbiology and Molecular Genetics from the Medical College of Wisconsin as well as an M.D. degree. He completed his residency training in Neurology at UCLA as well as a research fellowship in Neurogenetics. He is currently an Associate Professor in the Departments of Neurology and Human Genetics at the David Geffen School of Medicine at UCLA. Dr. Fogel’s research studies genomic methods to improve diagnosis of neurological disease, basic molecular mechanisms of neuronal function to understand how impairment can lead to neurodegenerative disorders such as cerebellar ataxia and develop new methods of treatment such as gene therapy, and the genetics of neurodevelopment to investigate conditions such as autism spectrum disorder and other neurological disorders. Clinically, Dr. Fogel directs the UCLA Neurogenetics Clinic where he is using genome-wide methods to identify rare and novel causes of neurodegenerative disease, particularly cerebellar ataxia, as well as other disorders including various forms of leukodystrophy and spastic paraparesis. Dr. Fogel is a member of the UCLA Ataxia Center and directs the Ataxia and Neurogenetics Biobank Program. Dr. Fogel also directs the Clinical Neurogenomics Research Center (CNRC) within the UCLA Department of Neurology. The CNRC facilitates incorporation of genomic data into clinical care and links patient populations with precision health-based research studies into the genetic and molecular basis of disease to improve diagnosis and treatment. He has authored many research and clinical articles, reviews, and book chapters on spinocerebellar ataxia, clinical neurogenetics, and neurodevelopmental disease. Dr. Fogel’s work has been funded by the American Academy of Neurology, the American Brain Foundation, the National Institutes of Health, and the National Ataxia Foundation.

Publications

A selected list of publications: