Jason Chiang

HS Assistant Clinical Professor, Radiological Sciences, University of California Los Angeles

Our interest is in using basic biomedical engineering/imaging principles to bridge the gap between bench top research and exceptional clinical care. We have longstanding collaborations with multiple departments within the UCLA School of Engineering and the UCLA School of Medicine. We pride ourselves in being able to speak both languages and leveraging each School’s strengths to improve patient care and long-term outcomes. Our work has primarily been involved in interventional oncology – using minimally-invasive tools under image guidance to treat early to intermediate-stage cancers. We aim to move the needle on cancer treatments using a three-pronged approach: 1) Computer simulation of medical devices and complex biological environments; 2) Validation of simulation results using phantom, ex-vivo, and in-vivo models; and 3) Optimizing medical devices and treatment techniques to improve outcomes directly to our clinical patient population.

Interests

In-vivo and ex-vivo validation, Medical device instrumentation, Numerical simulation, Solid oncology, Thermal ablation, Immunotherapy, Image guided therapy, Computational electromagnetic modeling, Minimally invasive cancer therapy

Education and Training

University of California, Los AngelesResident06/2022Interventional Radiology
University of WisconsinMD06/2016Medicine
University of WisconsinPhD06/2014Biomedical Engineering
Johns Hopkins UniversityBS06/2007Biomedical Engineering

Awards and Honors

  • Fulbright Grant, Tieraerztliche Hochschule Hannover, Germany, 2007.
  • Magna Cum Laude Educational Exhibit Award at the RSNA Annual Meeting, University of California - Los Angeles, 2017.
  • RSNA Trainee Research Prize, University of Wisconsin - Madison, 2011.
  • Phillips/RSNA Fellow Research Grant, University of California - Los Angeles, 2020.

Publications

  1. Lee J, Boas EF, Duran-Struuk R, Gaba R, Schachtschneider KM, Comin-Anduix B, Galic Z, Haile S, Bassir A, Chiang J. Pigs as clinically relevant models for synergizing interventional oncology and immunotherapy.. Journal of vascular and interventional radiology : JVIR, 2024.
  2. Chiang J, Chen PC, Pham J, Nguyen CQ, Kaur K, Raman SS, Jewett A. Characterizing hepatocellular carcinoma stem markers and their corresponding susceptibility to NK-cell based immunotherapy.. Frontiers in immunology, 2023.
  3. Chiang J, Rajendran PS, Hao F, Sayre J, Raman SS, Lu DSK, McWilliams JP. Combination transarterial chemoembolization and microwave ablation vs. microwave ablation monotherapy for hepatocellular carcinomas greater than 3 cm: a comparative study.. Diagnostic and interventional radiology (Ankara, Turkey), 2023.
  4. Chiang J, Sparks H, Rink JS, Meloni MF, Hao F, Sung KH, Lee EW. Dynamic Contrast-Enhanced MR Imaging Evaluation of Perfusional Changes and Ablation Zone Size after Combination Embolization and Ablation Therapy.. Journal of vascular and interventional radiology : JVIR, 2022.
  5. Karandikar A, Solberg A, Fung A, Lee AY, Farooq A, Taylor AC, Oliveira A, Narayan A, Senter A, Majid A, Tong A, McGrath AL, Malik A, Brown AL, Roberts A, Fleischer A, Vettiyil B, Zigmund B, Park B, Curran B, Henry C, Jaimes C, Connolly C, Robson C, Meltzer CC, Phillips CH, Dove C, Glastonbury C, Pomeranz C, Kirsch CFE, Burgan CM, Scher C, Tomblinson C, Fuss C, Santillan C, Daye D, Brown DB, Young DJ, Kopans D, Vargas D, Martin D, Thompson D, Jordan DW, Shatzkes D, Sun D, Mastrodicasa D, Smith E, Korngold E, Dibble EH, Arleo EK, Hecht EM, Morris E, Maltin EP, Cooke EA, Schwartz ES, Lehrman E, Sodagari F, Shah F, Doo FX, Rigiroli F, Vilanilam GK, Landinez G, Kim GG, Rahbar H, Choi H, Bandesha H, Ojeda-Fournier H, Ikuta I, Dragojevic I, Schroeder JLT, Ivanidze J, Katzen JT, Chiang J, Nguyen J, Robinson JD, Broder JC, Kemp J, Weaver JS, Conyers JM, Robbins JB, Leschied JR, Wen J, Park J, Mongan J, Perchik J, Barbero JPM, Jacob J, Ledbetter K, Macura KJ, Maturen KE, Frederick-Dyer K, Dodelzon K, Cort K, Kisling K, Babagbemi K, McGill KC, Chang KJ, Feigin K, Winsor KS, Seifert K, Patel K, Porter KK, Foley KM, Patel-Lippmann K, McIntosh LJ, Padilla L, Groner L, Harry LM, Ladd LM, Wang L, Spalluto LB, Mahesh M, Marx MV, Sugi MD, Sammer MBK, Sun M, Barkovich MJ, Miller MJ, Vella M, Davis MA, Englander MJ, Durst M, Oumano M, Wood MJ, McBee MP, Fischbein NJ, Kovalchuk N, Lall N, Eclov N, Madhuripan N, Ariaratnam NS, Vincoff NS, Kothary N, Yahyavi-Firouz-Abadi N, Brook OR, Glenn OA, Woodard PK, Mazaheri P, Rhyner P, Eby PR, Raghu P, Gerson RF, Patel R, Gutierrez RL, Gebhard R, Andreotti RF, Masum R, Woods R, Mandava S, Harrington SG, Parikh S, Chu S, Arora SS, Meyers SM, Prabhu S, Shams S, Pittman S, Patel SN, Payne S, Hetts SW, Hijaz TA, Chapman T, Loehfelm TW, Juang T, Clark TJ, Potigailo V, Shah V, Planz V, Kalia V, DeMartini W, Dillon WP, Gupta Y, Koethe Y, Hartley-Blossom Z, Wang ZJ, McGinty G, Haramati A, Allen LM, Germaine P. Radiologists staunchly support patient safety and autonomy, in opposition to the SCOTUS decision to overturn Roe v Wade.. Clinical imaging, 2022.
  6. Francica G, Meloni MF, Riccardi L, de Sio I, Caturelli E, Terracciano F, Giangregorio F, Chiang J, Danzi R, Marra A, Niosi M, Ranalli TV, Pompili M. Contrast-Enhanced Ultrasound Findings in Patients with Rare Solitary Necrotic Nodule of the Liver - a Multicenter Report.. Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2021.
  7. Chiang J, Song L, Abtin F, Rahmat-Samii Y. Efficacy of Lung-Tuned Monopole Antenna for Microwave Ablation: Analytical Solution and Validation in a Ventilator-Controlled ex Vivo Porcine Lung Model.. IEEE journal of electromagnetics, RF and microwaves in medicine and biology, 2021.
  8. Chiang J, Hebroni F, Bedayat A, Pourzand L. Case 286: Sarcoidlike Granulomatosis and Lymphadenopathy-Thoracic Manifestations of Nivolumab Drug Toxicity.. Radiology, 2021.
  9. Chiang J, Chiu HK, Moriarty JM, McWilliams JP. Hyperandrogenism and malignant degeneration of hepatic adenomas in the setting of Abernethy malformation.. Radiology case reports, 2020.
  10. Jamshidi N, Chiang J. Inline balloon-assisted vascular sheath fragment removal.. CVIR endovascular, 2020.
  11. Chiang J, Hebroni F, Bedayat A, Pourzand L. Case 286.. Radiology, 2020.
  12. Meloni MF, Francica G, Chiang J, Coltorti A, Danzi R, Laeseke PF. Use of Contrast-Enhanced Ultrasound in Ablation Therapy of HCC: Planning, Guiding, and Assessing Treatment Response.. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2020.
  13. Lingnan Song, Wuran Goo, Yahya Rahmat-Samii, Jason Chiang. 2020 IEEE International Symposium on Antennas and Propagation and North American Radio Science Meeting. Liquid metal-based tunable coaxial antenna for microwave ablation , 2020.
  14. Chiang J, Gershenson JP, Lewis MS, Vahidi K, Berenji GR. Focal 18F-NaF PET Prostate Activity in the Setting of Prostate Adenocarcinoma.. Clinical nuclear medicine, 2020.
  15. Bedayat A, Hassani C, Chiang J, Hebroni F, Ghandili S, Chalian H, Khoshpouri P, Lo HS, Karam AR. Abdominal wall and pelvic hernias: classic and unusual hernias and their mimics.. Clinical imaging, 2020.
  16. Chiang J, Loecher M, Moulin K, Meloni MF, Raman SS, McWilliams JP, Ennis DB, Lee EW. 4D Flow MR Imaging to Improve Microwave Ablation Prediction Models: A Feasibility Study in an In Vivo Porcine Liver.. Journal of vascular and interventional radiology : JVIR, 2020.
  17. Sievers P, Chiang J, Schrimpf D, Stichel D, Paramasivam N, Sill M, Gayden T, Casalini B, Reuss DE, Dalton J, Pajtler KW, Hänggi D, Herold-Mende C, Rushing E, Korshunov A, Mawrin C, Weller M, Schlesner M, Wick W, Jabado N, Jones DTW, Pfister SM, von Deimling A, Ellison DW, Sahm F. YAP1-fusions in pediatric NF2-wildtype meningioma.. Acta neuropathologica, 2019.
  18. Jason Chiang, MD, PhD; Neema Jamshidi, MD, PhD. Radiogenomics of Oncology: Current Trends and Future Directions. Advances in Clinical Radiology, 2019.
  19. Francica G, Meloni MF, Riccardi L, de Sio I, Terracciano F, Caturelli E, Iadevaia MD, Amoruso A, Roselli P, Chiang J, Scaglione M, Pompili M. Ablation treatment of primary and secondary liver tumors under contrast-enhanced ultrasound guidance in field practice of interventional ultrasound centers. A multicenter study.. European journal of radiology, 2018.
  20. Deng MY, Sill M, Chiang J, Schittenhelm J, Ebinger M, Schuhmann MU, Monoranu CM, Milde T, Wittmann A, Hartmann C, Sommer C, Paulus W, Gärtner J, Brück W, Rüdiger T, Leipold A, Jaunmuktane Z, Brandner S, Giangaspero F, Nozza P, Mora J, Morales la Madrid A, Cruz Martinez O, Hansford JR, Pietsch T, Tietze A, Hernáiz-Driever P, Stoler I, Capper D, Korshunov A, Ellison DW, von Deimling A, Pfister SM, Sahm F, Jones DTW. Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features.. Acta neuropathologica, 2018.
  21. Francica G, Meloni MF, de Sio I, Terracciano F, Caturelli E, Riccardi L, Roselli P, Iadevaia MD, Scaglione M, Lenna G, Chiang J, Pompili M. Biopsy of Liver Target Lesions under Contrast-Enhanced Ultrasound Guidance - A Multi-Center Study.. Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2017.
  22. Chiang J, Nickel K, Kimple RJ, Brace CL. Potential Mechanisms of Vascular Thrombosis after Microwave Ablation in an in Vivo Liver.. Journal of vascular and interventional radiology : JVIR, 2017.
  23. Santambrogio R, Chiang J, Barabino M, Meloni FM, Bertolini E, Melchiorre F, Opocher E. Comparison of Laparoscopic Microwave to Radiofrequency Ablation of Small Hepatocellular Carcinoma (≤3 cm).. Annals of surgical oncology, 2016.
  24. Meloni MF, Chiang J, Laeseke PF, Dietrich CF, Sannino A, Solbiati M, Nocerino E, Brace CL, Lee FT. Microwave ablation in primary and secondary liver tumours: technical and clinical approaches.. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2016.
  25. Chiang J, Cristescu M, Lee MH, Moreland A, Hinshaw JL, Lee FT, Brace CL. Effects of Microwave Ablation on Arterial and Venous Vasculature after Treatment of Hepatocellular Carcinoma.. Radiology, 2016.
  26. Jason Chiang, Christopher Brace. Feeding Structure for Dual Slot Microwave Ablation Probe. Feeding Structure for Dual Slot Microwave Ablation Probe, 2015.
  27. Bedoya M, del Rio AM, Chiang J, Brace CL. Microwave ablation energy delivery: influence of power pulsing on ablation results in an ex vivo and in vivo liver model.. Medical physics, 2014.
  28. Chiang J, Birla S, Bedoya M, Jones D, Subbiah J, Brace CL. Modeling and validation of microwave ablations with internal vaporization.. IEEE transactions on bio-medical engineering, 2014.
  29. Chiang J, Willey BJ, Del Rio AM, Hinshaw JL, Lee FT, Brace CL. Predictors of thrombosis in hepatic vasculature during microwave tumor ablation of an in vivo porcine model.. Journal of vascular and interventional radiology : JVIR, 2014.
  30. Gopal P, Yopp AC, Waljee AK, Chiang J, Nehra M, Kandunoori P, Singal AG. Factors that affect accuracy of α-fetoprotein test in detection of hepatocellular carcinoma in patients with cirrhosis.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013.
  31. Chiang J, Wang P, Brace CL. Computational modelling of microwave tumour ablations.. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2013.
  32. Chiang J, Hynes KA, Bedoya M, Brace CL. A dual-slot microwave antenna for more spherical ablation zones: ex vivo and in vivo validation.. Radiology, 2013.
  33. Chiang J, Hynes K, Brace CL. Flow-dependent vascular heat transfer during microwave thermal ablation.. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2012.
  34. Mirski MA, Ziai WC, Chiang J, Hinich M, Sherman D. Anticonvulsant serotonergic and deep brain stimulation in anterior thalamus.. Seizure, 2008.
  35. Hamani C, Hodaie M, Chiang J, del Campo M, Andrade DM, Sherman D, Mirski M, Mello LE, Lozano AM. Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticus.. Epilepsy research, 2007.