Publications

1. Radaic A, Kamarajan P, Cho A, Wang S, Hung GC, Najarzadegan F, Wong DT, Ton-That H, Wang CY, Kapila YL. Biological biomarkers of oral cancer.. Periodontology 2000, 2023.
2. Liu Z, Suh JS, Deng P, Bezouglaia O, Do M, Mirnia M, Cui ZK, Lee M, Aghaloo T, Wang CY, Hong C. Epigenetic Regulation of NGF-Mediated Osteogenic Differentiation in Human Dental Mesenchymal Stem Cells.. Stem cells (Dayton, Ohio), 2022.
3. Deng P, Chang I, Wang J, Badreldin AA, Li X, Yu B, Wang CY. Loss of KDM4B impairs osteogenic differentiation of OMSCs and promotes oral bone aging.. International journal of oral science, 2022.
4. Yu B, Wang CY. Osteoporosis and periodontal diseases - An update on their association and mechanistic links.. Periodontology 2000, 2022.
5. Liu Z, Lee HL, Suh JS, Deng P, Lee CR, Bezouglaia O, Mirnia M, Chen V, Zhou M, Cui ZK, Kim RH, Lee M, Aghaloo T, Hong C, Wang CY. The ERα/KDM6B regulatory axis modulates osteogenic differentiation in human mesenchymal stem cells.. Bone research, 2022.
6. Li X, Wang CY. From bulk, single-cell to spatial RNA sequencing.. International journal of oral science, 2021.
7. Elmusrati A, Wang J, Wang CY. Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma.. International journal of oral science, 2021.
8. Pouraghaei Sevari S, Kim JK, Chen C, Nasajpour A, Wang CY, Krebsbach PH, Khademhosseini A, Ansari S, Weiss PS, Moshaverinia A. Whitlockite-Enabled Hydrogel for Craniofacial Bone Regeneration.. ACS applied materials & interfaces, 2021.
9. Dong J, Li J, Li Y, Ma Z, Yu Y, Wang CY. Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma.. Nature communications, 2021.
10. Wang C, Li Y, Jia L, Kim JK, Li J, Deng P, Zhang W, Krebsbach PH, Wang CY. CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance.. Cell stem cell, 2021.
11. Jia L, Wang Y, Wang CY. circFAT1 Promotes Cancer Stemness and Immune Evasion by Promoting STAT3 Activation.. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021.
12. Zhang W, Liu W, Jia L, Chen D, Chang I, Lake M, Bentolila LA, Wang CY. Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress.. Molecular cell, 2021.
13. Deng P, Yuan Q, Cheng Y, Li J, Liu Z, Liu Y, Li Y, Su T, Wang J, Salvo ME, Wang W, Fan G, Lyons K, Yu B, Wang CY. Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging.. Cell stem cell, 2021.
14. Deng P, Yu Y, Hong C, Wang CY. Growth differentiation factor 6, a repressive target of EZH2, promotes the commitment of human embryonic stem cells to mesenchymal stem cells.. Bone research, 2020.
15. Zhou P, Wang J, Mishail D, Wang CY. Recent advancements in PARP inhibitors-based targeted cancer therapy.. Precision clinical medicine, 2020.
16. Jia L, Zhang W, Wang CY. BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse.. Cell stem cell, 2020.
17. Abril-Rodriguez G, Torrejon DY, Liu W, Zaretsky JM, Nowicki TS, Tsoi J, Puig-Saus C, Baselga-Carretero I, Medina E, Quist MJ, Garcia AJ, Senapedis W, Baloglu E, Kalbasi A, Cheung-Lau G, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Wang CY, Grasso CS, Ribas A. Publisher Correction: PAK4 inhibition improves PD-1 blockade immunotherapy.. Nature cancer, 2020.
18. Abril-Rodriguez G, Torrejon DY, Liu W, Zaretsky JM, Nowicki TS, Tsoi J, Puig-Saus C, Baselga-Carretero I, Medina E, Quist MJ, Garcia AJ, Senapedis W, Baloglu E, Kalbasi A, Cheung-Lau G, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Wang CY, Grasso CS, Ribas A. PAK4 inhibition improves PD-1 blockade immunotherapy.. Nature cancer, 2019.
19. Li J, Yu B, Deng P, Cheng Y, Yu Y, Kevork K, Ramadoss S, Ding X, Li X, Wang CY. Author Correction: KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling.. Nature communications, 2019.
20. Chen D, Wang CY. Targeting cancer stem cells in squamous cell carcinoma.. Precision clinical medicine, 2019.
21. Arai A, Kim S, Goldshteyn V, Kim T, Park NH, Wang CY, Kim RH. Beclin1 Modulates Bone Homeostasis by Regulating Osteoclast and Chondrocyte Differentiation.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019.
22. Suh JS, Kim S, Boström KI, Wang CY, Kim RH, Park NH. Periodontitis-induced systemic inflammation exacerbates atherosclerosis partly via endothelial-mesenchymal transition in mice.. International journal of oral science, 2019.
23. Alvarez R, Lee HL, Hong C, Wang CY. Author Correction: Single CD271 marker isolates mesenchymal stem cells from human dental pulp.. International journal of oral science, 2019.
24. Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, Luo X, Hong C, Lin J, Wang CY. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ.. Cell stem cell, 2018.
25. Cheng Y, Yuan Q, Vergnes L, Rong X, Youn JY, Li J, Yu Y, Liu W, Cai H, Lin JD, Tontonoz P, Hong C, Reue K, Wang CY. KDM4B protects against obesity and metabolic dysfunction.. Proceedings of the National Academy of Sciences of the United States of America, 2018.
26. Chen W, Kang KL, Alshaikh A, Varma S, Lin YL, Shin KH, Kim R, Wang CY, Park NH, Walentin K, Schmidt-Ott KM, Kang MK. Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways.. Oncogenesis, 2018.
27. Yu Y, Deng P, Yu B, Szymanski JM, Aghaloo T, Hong C, Wang CY. Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3.. Stem cell reports, 2017.
28. Hong C, Song D, Lee DK, Lin L, Pan HC, Lee D, Deng P, Liu Z, Hadaya D, Lee HL, Mohammad A, Zhang X, Lee M, Wang CY, Ho D. Reducing posttreatment relapse in cleft lip palatal expansion using an injectable estrogen-nanodiamond hydrogel.. Proceedings of the National Academy of Sciences of the United States of America, 2017.
29. Li J, Yu B, Deng P, Cheng Y, Yu Y, Kevork K, Ramadoss S, Ding X, Li X, Wang CY. KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling.. Nature communications, 2017.
30. Chen D, Wu M, Li Y, Chang I, Yuan Q, Ekimyan-Salvo M, Deng P, Yu B, Yu Y, Dong J, Szymanski JM, Ramadoss S, Li J, Wang CY. Targeting BMI1+ Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma.. Cell stem cell, 2017.
31. Cheng Y, Wang Y, Li J, Chang I, Wang CY. A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival.. Oncotarget, 2017.
32. King AD, Huang K, Rubbi L, Liu S, Wang CY, Wang Y, Pellegrini M, Fan G. Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells.. Cell reports, 2016.
33. Chang I, Wang CY. Inhibition of HDAC6 Protein Enhances Bortezomib-induced Apoptosis in Head and Neck Squamous Cell Carcinoma (HNSCC) by Reducing Autophagy.. The Journal of biological chemistry, 2016.
34. Yu B, Wang CY. Osteoporosis: The Result of an 'Aged' Bone Microenvironment.. Trends in molecular medicine, 2016.
35. Hoang M, Kim JJ, Kim Y, Tong E, Trammell B, Liu Y, Shi S, Lee CR, Hong C, Wang CY, Kim Y. Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells.. Stem cell research, 2016.
36. Hu Y, Huang K, An Q, Du G, Hu G, Xue J, Zhu X, Wang CY, Xue Z, Fan G. Simultaneous profiling of transcriptome and DNA methylome from a single cell.. Genome biology, 2016.
37. Deng P, Zhou C, Alvarez R, Hong C, Wang CY. Inhibition of IKK/NF-κB Signaling Enhances Differentiation of Mesenchymal Stromal Cells from Human Embryonic Stem Cells.. Stem cell reports, 2016.
38. Fan J, Im CS, Guo M, Cui ZK, Fartash A, Kim S, Patel N, Bezouglaia O, Wu BM, Wang CY, Aghaloo TL, Lee M. Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists.. Stem cells translational medicine, 2016.
39. Alvarez R, Lee HL, Wang CY, Hong C. Characterization of the osteogenic potential of mesenchymal stem cells from human periodontal ligament based on cell surface markers.. International journal of oral science, 2015.
40. Deng P, Chen QM, Hong C, Wang CY. Histone methyltransferases and demethylases: regulators in balancing osteogenic and adipogenic differentiation of mesenchymal stem cells.. International journal of oral science, 2015.
41. Alvarez R, Lee HL, Hong C, Wang CY. Single CD271 marker isolates mesenchymal stem cells from human dental pulp.. International journal of oral science, 2015.
42. Lee HL, Yu B, Deng P, Wang CY, Hong C. Transforming Growth Factor-β-Induced KDM4B Promotes Chondrogenic Differentiation of Human Mesenchymal Stem Cells.. Stem cells (Dayton, Ohio), 2015.
43. Tang ED, Wang CY. Single amino acid change in STING leads to constitutive active signaling.. PloS one, 2015.
44. Tang ED, Wang CY. YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation.. Cellular signalling, 2015.
45. Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, Graves DT, Park NH, Wang CY. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB.. Nature medicine, 2014.
46. Messadi DV, Younai FS, Liu HH, Guo G, Wang CY. The clinical effectiveness of reflectance optical spectroscopy for the in vivo diagnosis of oral lesions.. International journal of oral science, 2014.
47. Gong D, Wu NC, Xie Y, Feng J, Tong L, Brulois KF, Luan H, Du Y, Jung JU, Wang CY, Kang MK, Park NH, Sun R, Wu TT. Kaposi's sarcoma-associated herpesvirus ORF18 and ORF30 are essential for late gene expression during lytic replication.. Journal of virology, 2014.
48. Li J, Chen X, Ding X, Cheng Y, Zhao B, Lai ZC, Al Hezaimi K, Hakem R, Guan KL, Wang CY. LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.. Cell reports, 2013.
49. Xu J, Yu B, Hong C, Wang CY. KDM6B epigenetically regulates odontogenic differentiation of dental mesenchymal stem cells.. International journal of oral science, 2013.
50. Wu L, Zhao JC, Kim J, Jin HJ, Wang CY, Yu J. ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer.. Cancer research, 2013.
51. Chang J, Liu F, Lee M, Wu B, Ting K, Zara JN, Soo C, Al Hezaimi K, Zou W, Chen X, Mooney DJ, Wang CY. NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation.. Proceedings of the National Academy of Sciences of the United States of America, 2013.
52. Ding X, Pan H, Li J, Zhong Q, Chen X, Dry SM, Wang CY. Epigenetic activation of AP1 promotes squamous cell carcinoma metastasis.. Science signaling, 2013.
53. Ding X, Park SI, McCauley LK, Wang CY. Signaling between transforming growth factor β (TGF-β) and transcription factor SNAI2 represses expression of microRNA miR-203 to promote epithelial-mesenchymal transition and tumor metastasis.. The Journal of biological chemistry, 2013.
54. Ramadoss S, Chen X, Wang CY. Histone demethylase KDM6B promotes epithelial-mesenchymal transition.. The Journal of biological chemistry, 2012.
55. Ramadoss S, Li J, Ding X, Al Hezaimi K, Wang CY. Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation.. Molecular and cellular biology, 2010.
56. Krum SA, Chang J, Miranda-Carboni G, Wang CY. Novel functions for NFκB: inhibition of bone formation.. Nature reviews. Rheumatology, 2010.
57. Song J, Chang I, Chen Z, Kang M, Wang CY. Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling.. PloS one, 2010.
58. Kim J, Guan J, Chang I, Chen X, Han D, Wang CY. PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells.. Molecular cancer therapeutics, 2010.
59. Sun S, Wang Q, Giang A, Cheng C, Soo C, Wang CY, Liau LM, Chiu R. Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB.. Journal of neuro-oncology, 2010.
60. Tang ED, Wang CY. TRAF5 is a downstream target of MAVS in antiviral innate immune signaling.. PloS one, 2010.
61. Rehman AO, Wang CY. CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex.. International journal of oral science, 2009.
62. Fan Z, Yamaza T, Lee JS, Yu J, Wang S, Fan G, Shi S, Wang CY. BCOR regulates mesenchymal stem cell function by epigenetic mechanisms.. Nature cell biology, 2009.
63. Chang J, Wang Z, Tang E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY. Inhibition of osteoblastic bone formation by nuclear factor-kappaB.. Nature medicine, 2009.
64. Tang ED, Wang CY. MAVS self-association mediates antiviral innate immune signaling.. Journal of virology, 2009.
65. Rehman AO, Wang CY. SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB.. The Journal of biological chemistry, 2008.
66. Li J, Wang CY. TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis.. Nature cell biology, 2008.