Education and Training

Publications

1. Tran HL, Zheng W, Issadore DA, Im H, Cho YK, Zhang Y, Liu D, Liu Y, Li B, Liu F, Wong DTW, Sun J, Qian K, He M, Wan M, Zeng Y, Cheng K, Huang TJ, Chiu DT, Lee LP, Zheng L, Godwin AK, Kalluri R, Soper SA, Hu TY. Extracellular Vesicles for Clinical Diagnostics: From Bulk Measurements to Single-Vesicle Analysis.. ACS nano, 2025.
2. Qian J, Xia J, Chiang S, Liu JF, Li K, Li F, Wei F, Aziz M, Kim Y, Go V, Morizio J, Zhong R, He Y, Yang K, Yang OO, Wong DTW, Lee LP, Huang TJ. Rapid and comprehensive detection of viral antibodies and nucleic acids via an acoustofluidic integrated molecular diagnostics chip: AIMDx.. Science advances, 2025.
3. Mohammadi A, Chiang S, Li F, Wei F, Lau CS, Aziz M, Ibarrondo FJ, Fulcher JA, Yang OO, Chia D, Kim Y, Wong DTW. Direct detection of 4-dimensions of SARS-CoV-2: infection (vRNA), infectivity (antigen), binding antibody, and functional neutralizing antibody in saliva.. Scientific reports, 2024.
4. Nordham KD, Tatum D, Attia AS, Patel MB, Paramesh A, Duchesne JC, Nahmias J, Maiga AW, Peetz AB, Udekwu PO, Stiles A, Shell C, Stodghill JD, Maghsoudi T, Iacullo E, McLafferty B, Coonan E, Boudreau RM, Zimmerman SA, Shammassian B, Egodage T, Aramento I, Morris P, Metheny J, Farrell MS, Painter MD, McCabe OT, Spadafore P, Wong DT, Serrano J, Sciarretta JD, Kim P, Hayton R, Gonzales D, Murry J, Meadows K, Jacobson LE, Williams JM, Bernard AC, Smith B, Morrissey SL, Patel N, Tabello D, Teicher E, Chowdhury SM, Ahmad F, Marcos BS, West MA, Jacome TH, Davis G, Marks JA, Rattigan D, Haan JM, Lightwine K, Matsushima K, Park S, Santos A, Shrestha K, Sawyer R, VandenBerg S, Jean RJ, Hicks RC, Lueckel S, Bugaev N, Abosena W, Alvarez C, Lieser MJ, McDonald H, Dumas RP, Fitzgerald CA, Terzian WTH, Tian Y, Mousafeiris V, Mulita F, Berne JD, Mederos DR, Smith AA, Taghavi S. Impact of catastrophic brain injury guidelines on organ donation rates: Results of an EAST multicenter trial.. The journal of trauma and acute care surgery, 2024.
5. Haslam DE, Liang L, Guo K, Martínez-Lozano M, Pérez CM, Lee CH, Morou-Bermudez E, Clish C, Wong DTW, Manson JE, Hu FB, Stampfer MJ, Joshipura K, Bhupathiraju SN. Correction: Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults.. Diabetologia, 2024.
6. Kamounah S, Wei F, Park JK, Song YW, Chia D, Wong DTW, Pedersen AML. Corrigendum to paper entitled "Seronegative patients with primary Sjogren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva" [Published in: BBA - Mol. Basis Dis. Volume 1870, Issue 5, June 2024, 167168].. Biochimica et biophysica acta. Molecular basis of disease, 2024.
7. Khanani AM, Sadda SR, Sarraf D, Tadayoni R, Wong DT, Kempf AS, Saffar I, Gedif K, Chang A. Effect of Brolucizumab and Aflibercept on the Maximum Thickness of Pigment Epithelial Detachments and Sub-Retinal Pigment Epithelium Fluid in HAWK and HARRIER.. Ophthalmology. Retina, 2024.
8. Cheng JC, Swarup N, Morselli M, Huang WL, Aziz M, Caggiano C, Kordi M, Patel AA, Chia D, Kim Y, Li F, Wei F, Zaitlen N, Krysan K, Dubinett S, Pellegrini M, Wong DTW. Single-stranded pre-methylated 5mC adapters uncover the methylation profile of plasma ultrashort Single-stranded cell-free DNA.. Nucleic acids research, 2024.
9. Haslam DE, Liang L, Guo K, Martínez-Lozano M, Pérez CM, Lee CH, Morou-Bermudez E, Clish C, Wong DTW, Manson JE, Hu FB, Stampfer MJ, Joshipura K, Bhupathiraju SN. Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults.. Diabetologia, 2024.
10. Kamounah S, Wei F, Park JK, Song YW, Chia D, Wong DTW, Pedersen AML. Seronegative patients with primary Sjögren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva.. Biochimica et biophysica acta. Molecular basis of disease, 2024.
11. Chiang S, Grogan T, Kamounah S, Wei F, Tayob N, Kim JY, Kyun Park J, Akin D, Elashoff DA, Pedersen AML, Song YW, Wong DTW, Chia D. Distinctive profile of monomeric and polymeric anti-SSA/Ro52 immunoglobulin A1 isoforms in saliva of patients with primary Sjögren's syndrome and Sicca.. RMD open, 2024.
12. Cheng JC, Swarup N, Wong DTW, Chia D. A review on the impact of single-stranded library preparation on plasma cell-free diversity for cancer detection.. Frontiers in oncology, 2024.
13. Mohammadi A, Chiang S, Li F, Wei F, Lau CS, Aziz M, Ibarrondo FJ, Fulcher JA, Yang OO, Chia D, Kim Y, Wong DTW. Direct Detection of 4-Dimensions of SARS-CoV-2: Infection (vRNA), Infectivity (Antigen), Binding Antibody, and Functional Neutralizing Antibody in Saliva.. Research square, 2023.
14. Radaic A, Kamarajan P, Cho A, Wang S, Hung GC, Najarzadegan F, Wong DT, Ton-That H, Wang CY, Kapila YL. Biological biomarkers of oral cancer.. Periodontology 2000, 2023.
15. Swarup N, Cheng J, Choi I, Heo YJ, Kordi M, Aziz M, Arora A, Li F, Chia D, Wei F, Elashoff D, Zhang L, Kim S, Kim Y, Wong DTW. Correction: Multi-faceted attributes of salivary cell-free DNA as liquid biopsy biomarkers for gastric cancer detection.. Biomarker research, 2023.
16. Cheng J, Swarup N, Li F, Kordi M, Lin CC, Yang SC, Huang WL, Aziz M, Kim Y, Chia D, Yeh YM, Wei F, Zheng D, Zhang L, Pellegrini M, Su WC, Wong DTW. Distinct Features of Plasma Ultrashort Single-Stranded Cell-Free DNA as Biomarkers for Lung Cancer Detection.. Clinical chemistry, 2023.
17. Swarup N, Cheng J, Choi I, Heo YJ, Kordi M, Aziz M, Arora A, Li F, Chia D, Wei F, Elashoff D, Zhang L, Kim S, Kim Y, Wong DTW. Multi-faceted attributes of salivary cell-free DNA as liquid biopsy biomarkers for gastric cancer detection.. Biomarker research, 2023.
18. Batool SM, Yekula A, Khanna P, Hsia T, Gamblin AS, Ekanayake E, Escobedo AK, You DG, Castro CM, Im H, Kilic T, Garlin MA, Skog J, Dinulescu DM, Dudley J, Agrawal N, Cheng J, Abtin F, Aberle DR, Chia D, Elashoff D, Grognan T, Krysan K, Oh SS, Strom C, Tu M, Wei F, Xian RR, Skates SJ, Zhang DY, Trinh T, Watson M, Aft R, Rawal S, Agarwal A, Kesmodel SB, Yang C, Shen C, Hochberg FH, Wong DTW, Patel AA, Papadopoulos N, Bettegowda C, Cote RJ, Srivastava S, Lee H, Carter BS, Balaj L. The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring.. Cell reports. Medicine, 2023.
19. Swarup N, Cheng J, Choi I, Heo YJ, Kordi M, Li F, Aziz M, Chia D, Wei F, Elashoff D, Zhang L, Kim S, Kim Y, Wong DTW. Multi-Faceted Attributes of Salivary Cell-free DNA as Liquid Biopsy Biomarkers for Gastric Cancer Detection.. Research square, 2023.
20. Kamounah S, Tayob N, Chiang S, Wei F, Park JK, Kwon HM, Feng Z, Chia D, Pedersen AML, Song YW, Wong DTW. Immunoassay Detects Salivary Anti-SSA/Ro-52 Autoantibodies in Seronegative Patients with Primary Sjögren's Syndrome.. ImmunoHorizons, 2023.
21. Wei F, Yu P, Cheng J, Li F, Chia D, Wong DTW. Single-Droplet Microsensor for Ultra-Short Circulating EFGR Mutation Detection in Lung Cancer Based on Multiplex EFIRM Liquid Biopsy.. International journal of molecular sciences, 2023.
22. Salfer B, Havo D, Kuppinger S, Wong DTW, Li F, Zhang L. Evaluating Pre-Analytical Variables for Saliva Cell-Free DNA Liquid Biopsy.. Diagnostics (Basel, Switzerland), 2023.
23. Bansal A, Hamli H, Lee WW, Sarraf D, Sadda S, Berger AR, Wong DT, Kertes PJ, Kohly RP, Hillier RJ, Muni RH. En Face OCT in Diagnosis of Persistent Subretinal Fluid and Outer Retinal Folds after Rhegmatogenous Retinal Detachment Repair.. Ophthalmology. Retina, 2023.
24. Kaczor-Urbanowicz KE, Wong DTW. RNA Sequencing Analysis of Saliva exRNA.. Methods in molecular biology (Clifton, N.J.), 2023.
25. Zhang J, Chen C, Becker R, Rufo J, Yang S, Mai J, Zhang P, Gu Y, Wang Z, Ma Z, Xia J, Hao N, Tian Z, Wong DTW, Sadovsky Y, Lee LP, Huang TJ. A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER).. Science advances, 2022.
26. Liu Z, Li T, Wang Z, Liu J, Huang S, Min BH, An JY, Kim KM, Kim S, Chen Y, Liu H, Kim Y, Wong DTW, Huang TJ, Xie YH. Gold Nanopyramid Arrays for Non-Invasive Surface-Enhanced Raman Spectroscopy-Based Gastric Cancer Detection via sEVs.. ACS applied nano materials, 2022.
27. Bansal A, Lee WW, Sarraf D, Sadda SR, Berger AR, Wong DT, Kertes PJ, Kohly RP, Hillier RJ, Muni RH. Persistent subfoveal fluid in pneumatic retinopexy versus pars plana vitrectomy for rhegmatogenous retinal detachment: posthoc analysis of the PIVOT randomised trial.. The British journal of ophthalmology, 2022.
28. Kaczor-Urbanowicz KE, Saad M, Grogan TR, Li F, Heo YJ, Elashoff D, Bresalier RS, Wong DTW, Kim Y. Performance of Salivary Extracellular RNA Biomarker Panels for Gastric Cancer Differs between Distinct Populations.. Cancers, 2022.
29. Li F, Wei F, Grogan TR, Elashoff DE, Vu D, Vigerust DJ, Gupta R, Wong DTW. Proficiency Testing of Epidermal Growth Factor Receptor Mutations Detection in Saliva Using Spectrum Saliva Collector (SDNA-1000) and Preservative Solution Detected by Electric Field-Induced Release and Measurement.. Biopreservation and biobanking, 2022.
30. Mateescu B, Jones JC, Alexander RP, Alsop E, An JY, Asghari M, Boomgarden A, Bouchareychas L, Cayota A, Chang HC, Charest A, Chiu DT, Coffey RJ, Das S, De Hoff P, deMello A, D'Souza-Schorey C, Elashoff D, Eliato KR, Franklin JL, Galas DJ, Gerstein MB, Ghiran IH, Go DB, Gould S, Grogan TR, Higginbotham JN, Hladik F, Huang TJ, Huo X, Hutchins E, Jeppesen DK, Jovanovic-Talisman T, Kim BYS, Kim S, Kim KM, Kim Y, Kitchen RR, Knouse V, LaPlante EL, Lebrilla CB, Lee LJ, Lennon KM, Li G, Li F, Li T, Liu T, Liu Z, Maddox AL, McCarthy K, Meechoovet B, Maniya N, Meng Y, Milosavljevic A, Min BH, Morey A, Ng M, Nolan J, De Oliveira Junior GP, Paulaitis ME, Phu TA, Raffai RL, Reátegui E, Roth ME, Routenberg DA, Rozowsky J, Rufo J, Senapati S, Shachar S, Sharma H, Sood AK, Stavrakis S, Stürchler A, Tewari M, Tosar JP, Tucker-Schwartz AK, Turchinovich A, Valkov N, Van Keuren-Jensen K, Vickers KC, Vojtech L, Vreeland WN, Wang C, Wang K, Wang Z, Welsh JA, Witwer KW, Wong DTW, Xia J, Xie YH, Yang K, Zaborowski MP, Zhang C, Zhang Q, Zivkovic AM, Laurent LC. Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.. iScience, 2022.
31. Cheng J, Morselli M, Huang WL, Heo YJ, Pinheiro-Ferreira T, Li F, Wei F, Chia D, Kim Y, He HJ, Cole KD, Su WC, Pellegrini M, Wong DTW. Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNA.. iScience, 2022.
32. Cohn W, Zhu C, Campagna J, Bilousova T, Spilman P, Teter B, Li F, Guo R, Elashoff D, Cole GM, Avidan A, Faull KF, Whitelegge J, Wong DTW, John V. Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.. International journal of molecular sciences, 2022.
33. Munk MR, Kashani AH, Tadayoni R, Korobelnik JF, Wolf S, Pichi F, Koh A, Ishibazawa A, Gaudric A, Loewenstein A, Lumbroso B, Ferrara D, Sarraf D, Wong DT, Skondra D, Rodriguez FJ, Staurenghi G, Pearce I, Kim JE, Freund KB, Parodi MB, Waheed NK, Rosen R, Spaide RF, Nakao S, Sadda S, Vujosevic S, Wong TY, Murata T, Chakravarthy U, Ogura Y, Huf W, Tian M. Recommendations for OCT Angiography Reporting in Retinal Vascular Disease: A Delphi Approach by International Experts.. Ophthalmology. Retina, 2022.
34. Dinis M, Agnello M, Cen L, Shokeen B, He X, Shi W, Wong DTW, Lux R, Tran NC. Oral Microbiome: Streptococcus mutans/Caries Concordant-Discordant Children.. Frontiers in microbiology, 2022.
35. Figueiredo N, Sarraf D, Gunnemann F, Sadda SR, Bansal A, Berger AR, Wong DT, Kohly RP, Kertes PJ, Hillier RJ, Muni RH. Longitudinal Assessment of Ellipsoid Zone Recovery Using En Face Optical Coherence Tomography After Retinal Detachment Repair.. American journal of ophthalmology, 2021.
36. Lee WW, Bansal A, Sadda SR, Sarraf D, Berger AR, Wong DT, Kertes PJ, Kohly RP, Hillier RJ, Muni RH. Outer Retinal Folds after Pars Plana Vitrectomy vs. Pneumatic Retinopexy for Retinal Detachment Repair: Post hoc analysis from PIVOT.. Ophthalmology. Retina, 2021.
37. Haslam DE, Liang L, Wang DD, Kelly RS, Wittenbecher C, Pérez CM, Martínez M, Lee CH, Clish CB, Wong DTW, Parnell LD, Lai CQ, Ordovás JM, Manson JE, Hu FB, Stampfer MJ, Tucker KL, Joshipura KJ, Bhupathiraju SN. Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent.. BMJ open diabetes research & care, 2021.
38. Kim C, Xi L, Cultraro CM, Wei F, Jones G, Cheng J, Shafiei A, Pham TH, Roper N, Akoth E, Ghafoor A, Misra V, Monkash N, Strom C, Tu M, Liao W, Chia D, Morris C, Steinberg SM, Bagheri H, Wong DTW, Raffeld M, Guha U. Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma.. Cancers, 2021.
39. Chiang SH, Tu M, Cheng J, Wei F, Li F, Chia D, Garner O, Chandrasekaran S, Bender R, Strom CM, Wong DTW. Development and validation of a quantitative, non-invasive, highly sensitive and specific, electrochemical assay for anti-SARS-CoV-2 IgG antibodies in saliva.. PloS one, 2021.
40. Muni RH, Felfeli T, Sadda SR, Juncal VR, Francisconi CLM, Nittala MG, Lindenberg S, Gunnemann F, Berger AR, Wong DT, Altomare F, Giavedoni LR, Kohly RP, Kertes PJ, Sarraf D, Hillier RJ. Postoperative Photoreceptor Integrity Following Pneumatic Retinopexy vs Pars Plana Vitrectomy for Retinal Detachment Repair: A Post Hoc Optical Coherence Tomography Analysis From the Pneumatic Retinopexy Versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial.. JAMA ophthalmology, 2021.
41. Gu Y, Chen C, Mao Z, Bachman H, Becker R, Rufo J, Wang Z, Zhang P, Mai J, Yang S, Zhang J, Zhao S, Ouyang Y, Wong DTW, Sadovsky Y, Huang TJ. Acoustofluidic centrifuge for nanoparticle enrichment and separation.. Science advances, 2021.
42. Chiang SH, Tu M, Cheng J, Wei F, Li F, Chia D, Garner O, Chandrasekaran S, Bender R, Strom CM, Wong DTW. Development and validation of a highly sensitive and specific electrochemical assay to quantify anti-SARS-CoV-2 IgG antibodies to facilitate pandemic surveillance and monitoring of vaccine response.. medRxiv : the preprint server for health sciences, 2020.
43. Tavanasefat H, Li F, Koyano K, Gourtani BK, Marty V, Mulpuri Y, Lee SH, Shin KH, Wong DTW, Xiao X, Spigelman I, Kim Y. Molecular consequences of fetal alcohol exposure on amniotic exosomal miRNAs with functional implications for stem cell potency and differentiation.. PloS one, 2020.
44. Kaczor-Urbanowicz KE, Cheng J, King JC, Sedarat A, Pandol SJ, Farrell JJ, Wong DTW, Kim Y. Reviews on Current Liquid Biopsy for Detection and Management of Pancreatic Cancers.. Pancreas, 2020.
45. Li N, Guha U, Kim C, Ye L, Cheng J, Li F, Chia D, Wei F, Wong DTW. Longitudinal Monitoring of EGFR and PIK3CA Mutations by Saliva-Based EFIRM in Advanced NSCLC Patients With Local Ablative Therapy and Osimertinib Treatment: Two Case Reports.. Frontiers in oncology, 2020.
46. Li F, Wei F, Huang WL, Lin CC, Li L, Shen MM, Yan Q, Liao W, Chia D, Tu M, Tang JH, Feng Z, Kim Y, Su WC, Wong DTW. Ultra-Short Circulating Tumor DNA (usctDNA) in Plasma and Saliva of Non-Small Cell Lung Cancer (NSCLC) Patients.. Cancers, 2020.
47. Tu M, Cheng J, Chen YL, Jea WC, Chen WL, Chen CJ, Ho CL, Huang WL, Lin CC, Su WC, Ye Q, Deignan J, Grody W, Li F, Chia D, Wei F, Liao W, Wong DTW, Strom CM. Electric Field-Induced Release and Measurement (EFIRM): Characterization and Technical Validation of a Novel Liquid Biopsy Platform in Plasma and Saliva.. The Journal of molecular diagnostics : JMD, 2020.
48. Wang Z, Li F, Rufo J, Chen C, Yang S, Li L, Zhang J, Cheng J, Kim Y, Wu M, Abemayor E, Tu M, Chia D, Spruce R, Batis N, Mehanna H, Wong DTW, Huang TJ. Acoustofluidic Salivary Exosome Isolation: A Liquid Biopsy Compatible Approach for Human Papillomavirus-Associated Oropharyngeal Cancer Detection.. The Journal of molecular diagnostics : JMD, 2020.
49. Kaczor-Urbanowicz KE, Wei F, Rao SL, Kim J, Shin H, Cheng J, Tu M, Wong DTW, Kim Y. Clinical validity of saliva and novel technology for cancer detection.. Biochimica et biophysica acta. Reviews on cancer, 2019.
50. Murillo OD, Thistlethwaite W, Rozowsky J, Subramanian SL, Lucero R, Shah N, Jackson AR, Srinivasan S, Chung A, Laurent CD, Kitchen RR, Galeev T, Warrell J, Diao JA, Welsh JA, Hanspers K, Riutta A, Burgstaller-Muehlbacher S, Shah RV, Yeri A, Jenkins LM, Ahsen ME, Cordon-Cardo C, Dogra N, Gifford SM, Smith JT, Stolovitzky G, Tewari AK, Wunsch BH, Yadav KK, Danielson KM, Filant J, Moeller C, Nejad P, Paul A, Simonson B, Wong DK, Zhang X, Balaj L, Gandhi R, Sood AK, Alexander RP, Wang L, Wu C, Wong DTW, Galas DJ, Van Keuren-Jensen K, Patel T, Jones JC, Das S, Cheung KH, Pico AR, Su AI, Raffai RL, Laurent LC, Roth ME, Gerstein MB, Milosavljevic A. exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids.. Cell, 2019.
51. Cheng J, Nonaka T, Wong DTW. Salivary Exosomes as Nanocarriers for Cancer Biomarker Delivery.. Materials (Basel, Switzerland), 2019.
52. Ishikawa S, Wong DTW, Sugimoto M, Gleber-Netto FO, Li F, Tu M, Zhang Y, Akin D, Iino M. Identification of salivary metabolites for oral squamous cell carcinoma and oral epithelial dysplasia screening from persistent suspicious oral mucosal lesions.. Clinical oral investigations, 2018.
53. Wei F, Strom CM, Cheng J, Lin CC, Hsu CY, Soo Hoo GW, Chia D, Kim Y, Li F, Elashoff D, Grognan T, Tu M, Liao W, Xian R, Grody WW, Su WC, Wong DTW. Electric Field-Induced Release and Measurement Liquid Biopsy for Noninvasive Early Lung Cancer Assessment.. The Journal of molecular diagnostics : JMD, 2018.
54. Li F, Yoshizawa JM, Kim KM, Kanjanapangka J, Grogan TR, Wang X, Elashoff DE, Ishikawa S, Chia D, Liao W, Akin D, Yan X, Lee MS, Choi R, Kim SM, Kang SY, Bae JM, Sohn TS, Lee JH, Choi MG, Min BH, Lee JH, Kim JJ, Kim Y, Kim S, Wong DTW. Discovery and Validation of Salivary Extracellular RNA Biomarkers for Noninvasive Detection of Gastric Cancer.. Clinical chemistry, 2018.
55. Kaczor-Urbanowicz KE, Trivedi HM, Lima PO, Camargo PM, Giannobile WV, Grogan TR, Gleber-Netto FO, Whiteman Y, Li F, Lee HJ, Dharia K, Aro K, Martin Carreras-Presas C, Amuthan S, Vartak M, Akin D, Al-Adbullah H, Bembey K, Klokkevold PR, Elashoff D, Barnes VM, Richter R, DeVizio W, Masters JG, Wong DTW. Salivary exRNA biomarkers to detect gingivitis and monitor disease regression.. Journal of clinical periodontology, 2018.
56. Li F, Kaczor-Urbanowicz KE, Sun J, Majem B, Lo HC, Kim Y, Koyano K, Rao SL, Kang SY, Kim SM, Kim KM, Kim S, Chia D, Elashoff D, Grogan TR, Xiao X, Wong DTW. Characterization of Human Salivary Extracellular RNA by Next-generation Sequencing.. Clinical chemistry, 2018.
57. Kaczor-Urbanowicz KE, Kim Y, Li F, Galeev T, Kitchen RR, Gerstein M, Koyano K, Jeong SH, Wang X, Elashoff D, Kang SY, Kim SM, Kim K, Kim S, Chia D, Xiao X, Rozowsky J, Wong DTW. Novel approaches for bioinformatic analysis of salivary RNA sequencing data for development.. Bioinformatics (Oxford, England), 2018.
58. Nonaka T, Wong DTW. Saliva-Exosomics in Cancer: Molecular Characterization of Cancer-Derived Exosomes in Saliva.. The Enzymes, 2017.
59. Zhang Y, Sun J, Li F, Grogan TR, Vergara JL, Luan Q, Park MS, Chia D, Elashoff D, Joshipura KJ, Wong DTW. Salivary extracellular RNA biomarkers for insulin resistance detection in hispanics.. Diabetes research and clinical practice, 2017.
60. Majem B, Li F, Sun J, Wong DT. RNA Sequencing Analysis of Salivary Extracellular RNA.. Methods in molecular biology (Clifton, N.J.), 2017.
61. Wang X, Kaczor-Urbanowicz KE, Wong DT. Salivary biomarkers in cancer detection.. Medical oncology (Northwood, London, England), 2016.
62. Katsiougiannis S, Chia D, Kim Y, Singh RP, Wong DT. Saliva exosomes from pancreatic tumor-bearing mice modulate NK cell phenotype and antitumor cytotoxicity.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016.
63. Kaczor-Urbanowicz KE, Martín Carreras-Presas C, Kaczor T, Tu M, Wei F, Garcia-Godoy F, Wong DT. Emerging technologies for salivaomics in cancer detection.. Journal of cellular and molecular medicine, 2016.
64. Katsiougiannis S, Wong DT. The Proteomics of Saliva in Sjögren's Syndrome.. Rheumatic diseases clinics of North America, 2016.
65. Pu D, Liang H, Wei F, Akin D, Feng Z, Yan Q, Li Y, Zhen Y, Xu L, Dong G, Wan H, Dong J, Qiu X, Qin C, Zhu D, Wang X, Sun T, Zhang W, Li C, Tang X, Qiao Y, Wong DT, Zhou Q. Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study.. Thoracic cancer, 2016.
66. Xiao H, Zhang Y, Kim Y, Kim S, Kim JJ, Kim KM, Yoshizawa J, Fan LY, Cao CX, Wong DT. Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection.. Scientific reports, 2016.
67. Gleber-Netto FO, Yakob M, Li F, Feng Z, Dai J, Kao HK, Chang YL, Chang KP, Wong DT. Salivary Biomarkers for Detection of Oral Squamous Cell Carcinoma in a Taiwanese Population.. Clinical cancer research : an official journal of the American Association for Cancer Research, 2016.
68. Matse JH, Yoshizawa J, Wang X, Elashoff D, Bolscher JG, Veerman EC, Leemans CR, Pegtel DM, Pegtel MD, Wong DT, Bloemena E. Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms.. PloS one, 2015.
69. Lin CC, Huang WL, Wei F, Su WC, Wong DT. Emerging platforms using liquid biopsy to detect EGFR mutations in lung cancer.. Expert review of molecular diagnostics, 2015.
70. Huang WL, Wei F, Wong DT, Lin CC, Su WC. The Emergent Landscape of Detecting EGFR Mutations Using Circulating Tumor DNA in Lung Cancer.. BioMed research international, 2015.
71. Chai YD, Zhang L, Yang Y, Su T, Charugundla P, Ai J, Messadi D, Wong DT, Hu S. Discovery of potential serum protein biomarkers for lymph node metastasis in oral cancer.. Head & neck, 2015.
72. Lin X, Lo HC, Wong DT, Xiao X. Noncoding RNAs in human saliva as potential disease biomarkers.. Frontiers in genetics, 2015.
73. Majem B, Rigau M, Reventós J, Wong DT. Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics.. International journal of molecular sciences, 2015.
74. Wong DT. Salivary extracellular noncoding RNA: emerging biomarkers for molecular diagnostics.. Clinical therapeutics, 2015.
75. Chiang SH, Thomas GA, Liao W, Grogan T, Buck RL, Fuentes L, Yakob M, Laughlin MJ, Schafer C, Nazmul-Hossain A, Wei F, Elashoff D, Slowey PD, Wong DT. RNAPro•SAL: a device for rapid and standardized collection of saliva RNA and proteins.. BioTechniques, 2015.
76. Wei F, Lin CC, Joon A, Feng Z, Troche G, Lira ME, Chia D, Mao M, Ho CL, Su WC, Wong DT. Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer.. American journal of respiratory and critical care medicine, 2014.
77. Bahn JH, Zhang Q, Li F, Chan TM, Lin X, Kim Y, Wong DT, Xiao X. The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva.. Clinical chemistry, 2014.
78. Deutsch O, Krief G, Konttinen YT, Zaks B, Wong DT, Aframian DJ, Palmon A. Identification of Sjögren's syndrome oral fluid biomarker candidates following high-abundance protein depletion.. Rheumatology (Oxford, England), 2014.
79. Singh RP, Hasan S, Sharma S, Nagra S, Yamaguchi DT, Wong DT, Hahn BH, Hossain A. Th17 cells in inflammation and autoimmunity.. Autoimmunity reviews, 2014.
80. Yakob M, Fuentes L, Wang MB, Abemayor E, Wong DT. Salivary biomarkers for detection of oral squamous cell carcinoma - current state and recent advances.. Current oral health reports, 2014.
81. Zhang Y, Sun J, Lin CC, Abemayor E, Wang MB, Wong DT. The emerging landscape of salivary diagnostics.. Oral health and dental management, 2014.
82. Schafer CA, Schafer JJ, Yakob M, Lima P, Camargo P, Wong DT. Saliva diagnostics: utilizing oral fluids to determine health status.. Monographs in oral science, 2014.
83. Yoshizawa JM, Schafer CA, Schafer JJ, Farrell JJ, Paster BJ, Wong DT. Salivary biomarkers: toward future clinical and diagnostic utilities.. Clinical microbiology reviews, 2013.
84. Lau C, Kim Y, Chia D, Spielmann N, Eibl G, Elashoff D, Wei F, Lin YL, Moro A, Grogan T, Chiang S, Feinstein E, Schafer C, Farrell J, Wong DT. Role of pancreatic cancer-derived exosomes in salivary biomarker development.. The Journal of biological chemistry, 2013.
85. Wei F, Yang J, Wong DT. Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM).. Biosensors & bioelectronics, 2013.
86. Yoshizawa JM, Wong DT. Salivary microRNAs and oral cancer detection.. Methods in molecular biology (Clifton, N.J.), 2013.
87. Bonne NJ, Wong DT. Salivary biomarker development using genomic, proteomic and metabolomic approaches.. Genome medicine, 2012.
88. Kim JJ, Khalid O, Vo S, Sun HH, Wong DT, Kim Y. A novel regulatory factor recruits the nucleosome remodeling complex to wingless integrated (Wnt) signaling gene promoters in mouse embryonic stem cells.. The Journal of biological chemistry, 2012.
89. Wong DT. Salivaomics.. Journal of the American Dental Association (1939), 2012.
90. Spielmann N, Ilsley D, Gu J, Lea K, Brockman J, Heater S, Setterquist R, Wong DT. The human salivary RNA transcriptome revealed by massively parallel sequencing.. Clinical chemistry, 2012.
91. Deshpande AM, Khalid O, Kim JJ, Kim Y, Lindgren A, Clark AT, Wong DT. Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells.. Stem cells and development, 2012.
92. Zhang L, Xiao H, Zhou H, Santiago S, Lee JM, Garon EB, Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, Park NH, Wong DTW. Development of transcriptomic biomarker signature in human saliva to detect lung cancer.. Cellular and molecular life sciences : CMLS, 2012.
93. Elashoff D, Zhou H, Reiss J, Wang J, Xiao H, Henson B, Hu S, Arellano M, Sinha U, Le A, Messadi D, Wang M, Nabili V, Lingen M, Morris D, Randolph T, Feng Z, Akin D, Kastratovic DA, Chia D, Abemayor E, Wong DT. Prevalidation of salivary biomarkers for oral cancer detection.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012.
94. Farrell JJ, Zhang L, Zhou H, Chia D, Elashoff D, Akin D, Paster BJ, Joshipura K, Wong DT. Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer.. Gut, 2011.
95. Lee YH, Zhou H, Reiss JK, Yan X, Zhang L, Chia D, Wong DT. Direct saliva transcriptome analysis.. Clinical chemistry, 2011.
96. Hu S, Vissink A, Arellano M, Roozendaal C, Zhou H, Kallenberg CG, Wong DT. Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays.. Proteomics, 2011.
97. Brinkmann O, Zhang L, Giannobile WV, Wong DT. Salivary biomarkers for periodontal disease diagnostics.. Expert opinion on medical diagnostics, 2011.
98. Zhang L, Xiao H, Karlan S, Zhou H, Gross J, Elashoff D, Akin D, Yan X, Chia D, Karlan B, Wong DT. Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer.. PloS one, 2010.
99. Brinkmann O, Kastratovic DA, Dimitrijevic MV, Konstantinovic VS, Jelovac DB, Antic J, Nesic VS, Markovic SZ, Martinovic ZR, Akin D, Spielmann N, Zhou H, Wong DT. Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population.. Oral oncology, 2010.
100. Ai J, Smith B, Wong DT. Saliva Ontology: an ontology-based framework for a Salivaomics Knowledge Base.. BMC bioinformatics, 2010.
101. Ryan CM, Souda P, Halgand F, Wong DT, Loo JA, Faull KF, Whitelegge JP. Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry.. Journal of the American Society for Mass Spectrometry, 2010.
102. Halgand F, Zabrouskov V, Bassilian S, Souda P, Wong DT, Loo JA, Faull KF, Whitelegge JP. Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry.. Journal of the American Society for Mass Spectrometry, 2010.
103. Zhang L, Farrell JJ, Zhou H, Elashoff D, Akin D, Park NH, Chia D, Wong DT. Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer.. Gastroenterology, 2009.
104. Wei F, Liao W, Xu Z, Yang Y, Wong DT, Ho CM. Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis.. Small (Weinheim an der Bergstrasse, Germany), 2009.
105. Lee YH, Wong DT. Saliva: an emerging biofluid for early detection of diseases.. American journal of dentistry, 2009.
106. Kim Y, Deshpande A, Dai Y, Kim JJ, Lindgren A, Conway A, Clark AT, Wong DT. Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation.. The Journal of biological chemistry, 2009.
107. Gao K, Zhou H, Zhang L, Lee JW, Zhou Q, Hu S, Wolinsky LE, Farrell J, Eibl G, Wong DT. Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer.. PloS one, 2009.
108. Kim Y, McBride J, Kimlin L, Pae EK, Deshpande A, Wong DT. Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethality.. PloS one, 2009.
109. Hu S, Wong DT. Lectin microarray.. Proteomics. Clinical applications, 2009.
110. Hu S, Zhou M, Jiang J, Wang J, Elashoff D, Gorr S, Michie SA, Spijkervet FK, Bootsma H, Kallenberg CG, Vissink A, Horvath S, Wong DT. Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands.. Arthritis and rheumatism, 2009.
111. Deshpande AM, Dai YS, Kim Y, Kim J, Kimlin L, Gao K, Wong DT. Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation.. The Journal of biological chemistry, 2008.
112. Jiang J, Park NJ, Hu S, Wong DT. A universal pre-analytic solution for concurrent stabilization of salivary proteins, RNA and DNA at ambient temperature.. Archives of oral biology, 2008.
113. Hu S, Arellano M, Boontheung P, Wang J, Zhou H, Jiang J, Elashoff D, Wei R, Loo JA, Wong DT. Salivary proteomics for oral cancer biomarker discovery.. Clinical cancer research : an official journal of the American Association for Cancer Research, 2008.
114. Brooks MN, Wang J, Li Y, Zhang R, Elashoff D, Wong DT. Salivary protein factors are elevated in breast cancer patients.. Molecular medicine reports, 2008.
115. Hu Z, Zimmermann BG, Zhou H, Wang J, Henson BS, Yu W, Elashoff D, Krupp G, Wong DT. Exon-level expression profiling: a comprehensive transcriptome analysis of oral fluids.. Clinical chemistry, 2008.
116. Wong DT. Salivary Diagnostics: Amazing as it might seem, doctors can detect and monitor diseases using molecules found in a sample of spit.. American scientist, 2008.
117. Zimmermann BG, Wong DT. Salivary mRNA targets for cancer diagnostics.. Oral oncology, 2007.
118. Whitelegge JP, Zabrouskov V, Halgand F, Souda P, Bassilian S, Yan W, Wolinsky L, Loo JA, Wong DT, Faull KF. Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry.. International journal of mass spectrometry, 2007.
119. Hu S, Yen Y, Ann D, Wong DT. Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery.. Drug discovery today, 2007.
120. Hu S, Wong DT. Oral cancer proteomics.. Current opinion in molecular therapeutics, 2007.
121. Zimmermann BG, Park NJ, Wong DT. Genomic targets in saliva.. Annals of the New York Academy of Sciences, 2007.
122. Hu S, Loo JA, Wong DT. Human saliva proteome analysis.. Annals of the New York Academy of Sciences, 2007.
123. Peng H, Shintani S, Kim Y, Wong DT. Loss of p12CDK2-AP1 expression in human oral squamous cell carcinoma with disrupted transforming growth factor-beta-Smad signaling pathway.. Neoplasia (New York, N.Y.), 2006.
124. Zhou X, Temam S, Oh M, Pungpravat N, Huang BL, Mao L, Wong DT. Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma.. Neoplasia (New York, N.Y.), 2006.
125. Park NJ, Li Y, Yu T, Brinkman BM, Wong DT. Characterization of RNA in saliva.. Clinical chemistry, 2006.
126. Wong DT. Salivary diagnostics powered by nanotechnologies, proteomics and genomics.. Journal of the American Dental Association (1939), 2006.
127. Li Y, Elashoff D, Oh M, Sinha U, St John MA, Zhou X, Abemayor E, Wong DT. Serum circulating human mRNA profiling and its utility for oral cancer detection.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006.
128. Zhou X, Yu T, Cole SW, Wong DT. Advancement in characterization of genomic alterations for improved diagnosis, treatment and prognostics in cancer.. Expert review of molecular diagnostics, 2006.
129. Gu F, Lux R, Du-Thumm L, Stokes I, Kreth J, Anderson MH, Wong DT, Wolinsky L, Sullivan R, Shi W. In situ and non-invasive detection of specific bacterial species in oral biofilms using fluorescently labeled monoclonal antibodies.. Journal of microbiological methods, 2005.
130. Figueiredo ML, Kim Y, St John MA, Wong DT. p12CDK2-AP1 gene therapy strategy inhibits tumor growth in an in vivo mouse model of head and neck cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005.
131. Zhou X, Rao NP, Cole SW, Mok SC, Chen Z, Wong DT. Progress in concurrent analysis of loss of heterozygosity and comparative genomic hybridization utilizing high density single nucleotide polymorphism arrays.. Cancer genetics and cytogenetics, 2005.
132. Kim Y, Ohyama H, Patel V, Figueiredo M, Wong DT. Mutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect.. The Journal of biological chemistry, 2005.
133. Kim Y, McBride J, Zhang R, Zhou X, Wong DT. p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.. Oncogene, 2005.
134. Kim Y, Shintani S, Kohno Y, Zhang R, Wong DT. Cyclin G2 dysregulation in human oral cancer.. Cancer research, 2004.
135. Li Y, St John MA, Zhou X, Kim Y, Sinha U, Jordan RC, Eisele D, Abemayor E, Elashoff D, Park NH, Wong DT. Salivary transcriptome diagnostics for oral cancer detection.. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004.
136. Hu S, Denny P, Denny P, Xie Y, Loo JA, Wolinsky LE, Li Y, McBride J, Ogorzalek Loo RR, Navazesh M, Wong DT. Differentially expressed protein markers in human submandibular and sublingual secretions.. International journal of oncology, 2004.
137. Zhou X, Mok SC, Chen Z, Li Y, Wong DT. Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array.. Human genetics, 2004.
138. St John MA, Li Y, Zhou X, Denny P, Ho CM, Montemagno C, Shi W, Qi F, Wu B, Sinha U, Jordan R, Wolinsky L, Park NH, Liu H, Abemayor E, Wong DT. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma.. Archives of otolaryngology--head & neck surgery, 2004.
139. Buajeeb W, Zhang X, Ohyama H, Han D, Surarit R, Kim Y, Wong DT. Interaction of the CDK2-associated protein-1, p12(DOC-1/CDK2AP1), with its homolog, p14(DOC-1R).. Biochemical and biophysical research communications, 2004.
140. Zhou X, Cole SW, Hu S, Wong DT. Detection of DNA copy number abnormality by microarray expression analysis.. Human genetics, 2004.
141. Hu MG, Hu GF, Kim Y, Tsuji T, McBride J, Hinds P, Wong DT. Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression.. Cancer research, 2004.
142. Kim Y, Donoff RB, Wong DT, Todd R. The nucleotide: DNA sequencing and its clinical application.. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2002.
143. Kim Y, Flynn TR, Donoff RB, Wong DT, Todd R. The gene: the polymerase chain reaction and its clinical application.. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2002.