Edward M De Robertis

Professor, Biological Chemistry, University of California Los Angeles

(310) 206-1463

Edward De Robertis is the Norman Sprague Professor of Biological Chemistry. He studies morphogen gradient formation in early development and in cancer. His work defined the Chordin/BMP/Tolloid signaling gradient, and the role of membrane trafficking in the generation of the Wnt canonical signal. De Robertis is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, the Academia de Ciencias de America Latina, EMBO, and the Pontifical Academy of Sciences of the Vatican.


Chordin/BMP/Tolloid pathway, Developmental Biology, Spemann organizer signaling, Bone Morphogenetic Proteins, Gastrulation, Wnt signaling, Colorectal cancer, Morphogen gradients in development, Cerberus head inducer

Education and Training

Universidad de la RepublicaMD03/1971Medicine

Awards and Honors

  • Doctor Honoris Causa, Universidad de la Republica del Uruguay, 2016.
  • Corresponding Member, Academia Nacional de Buenos Aires, 2019.
  • Member, National Academy of Sciences, 2013.
  • Gold Medal to top Medical Student, Universidad de la Republica, Uruguay, 1971.
  • Investigator, Howard Hughes Medical Institute, 1995-2019.
  • Doctor Honoris Causa, Universite Sorbonne, Paris, France, 2013.
  • Academician, Pontifical Academy of Sciences, The Vatican, 2009.
  • Corresponding Member, Academia Nacional del Uruguay, 2019.
  • Norman Sprague Chair in Molecular Oncology, UCLA School of Medicine, 1985-pres.
  • Lifetime Achievment Award, Society of Developmental Biology, 2021.
  • Membre D'Honneur, Societe de Biologie, Paris, France, 2008.
  • EMBO member, European Molecular Biology Organization, 1982.
  • Ross Harrison Prize in Developmental Biology, International Society of Developmental Biologists, 2009.
  • Kowalevsky Medal in Evo-Devo, Soc. of Naturalists, St. Petersburg, 2020.