Gerard Wong

Gerard Chee Lai Wong

Professor, Bioengineering, University of California Los Angeles

Professor, , University of California Los Angeles

Professor, Chemistry and Biochemistry, University of California Los Angeles

Professor, CA NanoSystems, University of California Los Angeles

Publications

  1. Wang Z, Zhao R, Wagenaar DA, Kang W, Lee C, Schmidt W, Pammar A, Zhu E, Wong GCL, Liang R, Hsiai T, Gao L. Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy.. bioRxiv : the preprint server for biology, 2024.
  2. de Anda J, Kuchma SL, Webster SS, Boromand A, Lewis KA, Lee CK, Contreras M, Medeiros Pereira VF, Schmidt W, Hogan DA, O'Hern CS, O'Toole GA, Wong GCL. How P. aeruginosa cells with diverse stator composition collectively swarm.. mBio, 2024.
  3. Zhang Y, Bharathi V, Dokoshi T, de Anda J, Ursery LT, Kulkarni NN, Nakamura Y, Chen J, Luo EWC, Wang L, Xu H, Coady A, Zurich R, Lee MW, Matsui T, Lee H, Chan LC, Schepmoes AA, Lipton MS, Zhao R, Adkins JN, Clair GC, Thurlow LR, Schisler JC, Wolfgang MC, Hagan RS, Yeaman MR, Weiss TM, Chen X, Li MMH, Nizet V, Antoniak S, Mackman N, Gallo RL, Wong GCL. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes.. Proceedings of the National Academy of Sciences of the United States of America, 2024.
  4. Alimohamadi H, Luo EW, Gupta S, de Anda J, Yang R, Mandal T, Wong GCL. Comparing multifunctional viral and eukaryotic proteins for generating scission necks in membranes.. bioRxiv : the preprint server for biology, 2024.
  5. Alimohamadi H, de Anda J, Lee MW, Schmidt NW, Mandal T, Wong GCL. How Cell-Penetrating Peptides Behave Differently from Pore-Forming Peptides: Structure and Stability of Induced Transmembrane Pores.. Journal of the American Chemical Society, 2023.
  6. Alimohamadi H, de Anda J, Lee MW, Schmidt NW, Mandal T, Wong GCL. How cell penetrating peptides behave differently from pore forming peptides: structure and stability of induced transmembrane pores.. bioRxiv : the preprint server for biology, 2023.
  7. de Anda J, Kuchma SL, Webster SS, Boromand A, Lewis KA, Lee CK, Contreras M, Pereira VFM, Hogan DA, O'Hern CS, O'Toole GA, Wong GCL. How individual P. aeruginosa cells with diverse stator distributions collectively form a heterogeneous macroscopic swarming population.. bioRxiv : the preprint server for biology, 2023.
  8. Egner JM, Nolden KA, Harwig MC, Bonate RP, De Anda J, Tessmer MH, Noey EL, Ihenacho UK, Liu Z, Peterson FC, Wong GCL, Widlansky ME, Hill RB. Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission.. The Journal of biological chemistry, 2022.
  9. Nicastro LK, de Anda J, Jain N, Grando KCM, Miller AL, Bessho S, Gallucci S, Wong GCL, Tükel Ç. Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses.. PLoS pathogens, 2022.
  10. Miller AL, de Anda J, Wong GCL, Tükel Ç. Amyloid-containing biofilms and autoimmunity.. Current opinion in structural biology, 2022.
  11. Webster SS, Wong GCL, O'Toole GA. The Power of Touch: Type 4 Pili, the von Willebrand A Domain, and Surface Sensing by Pseudomonas aeruginosa.. Journal of bacteriology, 2022.
  12. Grando K, Nicastro LK, Tursi SA, De Anda J, Lee EY, Wong GCL, Tükel Ç. Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity.. Frontiers in cellular and infection microbiology, 2022.
  13. Xian W, Hennefarth MR, Lee MW, Do T, Lee EY, Alexandrova AN, Wong GCL. Histidine-Mediated Ion Specific Effects Enable Salt Tolerance of a Pore-Forming Marine Antimicrobial Peptide.. Angewandte Chemie (International ed. in English), 2022.
  14. Lewis KA, Vermilyea DM, Webster SS, Geiger CJ, de Anda J, Wong GCL, O'Toole GA, Hogan DA. Nonmotile Subpopulations of Pseudomonas aeruginosa Repress Flagellar Motility in Motile Cells through a Type IV Pilus- and Pel-Dependent Mechanism.. Journal of bacteriology, 2022.
  15. Lee CK, Schmidt WC, Webster SS, Chen JW, O'Toole GA, Wong GCL. Broadcasting of amplitude- and frequency-modulated c-di-GMP signals facilitates cooperative surface commitment in bacterial lineages.. Proceedings of the National Academy of Sciences of the United States of America, 2022.
  16. Thorsen MK, Lai A, Lee MW, Hoogerheide DP, Wong GCL, Freed JH, Heldwein EE. Erratum for Thorsen et al., "Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering".. mBio, 2022.
  17. Lee MW, Luo EW, Silvestre-Roig C, Srinivasan Y, Akabori K, Lemnitzer P, Schmidt NW, Lai GH, Santangelo CD, Soehnlein O, Wong GCL. Apolipoprotein Mimetic Peptide Inhibits Neutrophil-Driven Inflammatory Damage via Membrane Remodeling and Suppression of Cell Lysis.. ACS nano, 2021.
  18. Cao B, Zhao Z, Peng L, Shiu HY, Ding M, Song F, Guan X, Lee CK, Huang J, Zhu D, Fu X, Wong GCL, Liu C, Nealson K, Weiss PS, Duan X, Huang Y. Silver nanoparticles boost charge-extraction efficiency in Shewanella microbial fuel cells.. Science (New York, N.Y.), 2021.
  19. Thorsen MK, Lai A, Lee MW, Hoogerheide DP, Wong GCL, Freed JH, Heldwein EE. Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering.. mBio, 2021.
  20. Webster SS, Lee CK, Schmidt WC, Wong GCL, O'Toole GA. Interaction between the type 4 pili machinery and a diguanylate cyclase fine-tune c-di-GMP levels during early biofilm formation.. Proceedings of the National Academy of Sciences of the United States of America, 2021.
  21. Wong GCL, Antani JD, Lele PP, Chen J, Nan B, Kühn MJ, Persat A, Bru JL, Høyland-Kroghsbo NM, Siryaporn A, Conrad JC, Carrara F, Yawata Y, Stocker R, V Brun Y, Whitfield GB, Lee CK, de Anda J, Schmidt WC, Golestanian R, O'Toole GA, Floyd KA, Yildiz FH, Yang S, Jin F, Toyofuku M, Eberl L, Nomura N, Zacharoff LA, El-Naggar MY, Yalcin SE, Malvankar NS, Rojas-Andrade MD, Hochbaum AI, Yan J, Stone HA, Wingreen NS, Bassler BL, Wu Y, Xu H, Drescher K, Dunkel J. Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation.. Physical biology, 2021.
  22. Kulkarni NN, O'Neill AM, Dokoshi T, Luo EWC, Wong GCL, Gallo RL. Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors.. The Journal of biological chemistry, 2021.
  23. Webster SS, Mathelié-Guinlet M, Verissimo AF, Schultz D, Viljoen A, Lee CK, Schmidt WC, Wong GCL, Dufrêne YF, O'Toole GA. Force-Induced Changes of PilY1 Drive Surface Sensing by Pseudomonas aeruginosa.. mBio, 2021.
  24. Lee EY, Chan LC, Wang H, Lieng J, Hung M, Srinivasan Y, Wang J, Waschek JA, Ferguson AL, Lee KF, Yount NY, Yeaman MR, Wong GCL. PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain.. Proceedings of the National Academy of Sciences of the United States of America, 2021.
  25. Zamorano-Sánchez D, Xian W, Lee CK, Salinas M, Thongsomboon W, Cegelski L, Wong GCL, Yildiz FH. Correction for Zamorano-Sánchez et al., "Functional Specialization in Vibrio cholerae Diguanylate Cyclases: Distinct Modes of Motility Suppression and c-di-GMP Production".. mBio, 2020.
  26. Yount NY, Weaver DC, de Anda J, Lee EY, Lee MW, Wong GCL, Yeaman MR. Discovery of Novel Type II Bacteriocins Using a New High-Dimensional Bioinformatic Algorithm.. Frontiers in immunology, 2020.
  27. Chen X, Yang X, de Anda J, Huang J, Li D, Xu H, Shields KS, Džunková M, Hansen J, Patel IJ, Yee EU, Golenbock DT, Grant MA, Wong GCL, Kelly CP. Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling.. Gastroenterology, 2020.
  28. Young TD, Liau WT, Lee CK, Mellody M, Wong GCL, Kasko AM, Weiss PS. Selective Promotion of Adhesion of Shewanella oneidensis on Mannose-Decorated Glycopolymer Surfaces.. ACS applied materials & interfaces, 2020.
  29. Lee EY, Srinivasan Y, de Anda J, Nicastro LK, Tükel Ç, Wong GCL. Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation.. Frontiers in immunology, 2020.
  30. He J, Thomas MA, de Anda J, Lee MW, Van Why E, Simpson P, Wong GCL, Grayson MH, Volkman BF, Huppler AR. Chemokine CCL28 Is a Potent Therapeutic Agent for Oropharyngeal Candidiasis.. Antimicrobial agents and chemotherapy, 2020.
  31. Klimovich A, Giacomello S, Björklund Å, Faure L, Kaucka M, Giez C, Murillo-Rincon AP, Matt AS, Willoweit-Ohl D, Crupi G, de Anda J, Wong GCL, D'Amato M, Adameyko I, Bosch TCG. Prototypical pacemaker neurons interact with the resident microbiota.. Proceedings of the National Academy of Sciences of the United States of America, 2020.
  32. Lee MW, de Anda J, Kroll C, Bieniossek C, Bradley K, Amrein KE, Wong GCL. How do cyclic antibiotics with activity against Gram-negative bacteria permeate membranes? A machine learning informed experimental study.. Biochimica et biophysica acta. Biomembranes, 2020.
  33. Dishman AF, Lee MW, de Anda J, Lee EY, He J, Huppler AR, Wong GCL, Volkman BF. Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1.. ACS infectious diseases, 2020.
  34. Floyd KA, Lee CK, Xian W, Nametalla M, Valentine A, Crair B, Zhu S, Hughes HQ, Chlebek JL, Wu DC, Hwan Park J, Farhat AM, Lomba CJ, Ellison CK, Brun YV, Campos-Gomez J, Dalia AB, Liu J, Biais N, Wong GCL, Yildiz FH. c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae.. Nature communications, 2020.
  35. Wu DC, Zamorano-Sánchez D, Pagliai FA, Park JH, Floyd KA, Lee CK, Kitts G, Rose CB, Bilotta EM, Wong GCL, Yildiz FH. Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation.. PLoS genetics, 2020.
  36. Lee CK, Vachier J, de Anda J, Zhao K, Baker AE, Bennett RR, Armbruster CR, Lewis KA, Tarnopol RL, Lomba CJ, Hogan DA, Parsek MR, O'Toole GA, Golestanian R, Wong GCL. Social Cooperativity of Bacteria during Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas aeruginosa PA14 and PAO1.. mBio, 2020.
  37. Belin BJ, Tookmanian EM, de Anda J, Wong GCL, Newman DK. Extended Hopanoid Loss Reduces Bacterial Motility and Surface Attachment and Leads to Heterogeneity in Root Nodule Growth Kinetics in a Bradyrhizobium-Aeschynomene Symbiosis.. Molecular plant-microbe interactions : MPMI, 2019.
  38. Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.. Nature, 2019.
  39. Zamorano-Sánchez D, Xian W, Lee CK, Salinas M, Thongsomboon W, Cegelski L, Wong GCL, Yildiz FH. Functional Specialization in Vibrio cholerae Diguanylate Cyclases: Distinct Modes of Motility Suppression and c-di-GMP Production.. mBio, 2019.
  40. Yount NY, Weaver DC, Lee EY, Lee MW, Wang H, Chan LC, Wong GCL, Yeaman MR. Unifying structural signature of eukaryotic α-helical host defense peptides.. Proceedings of the National Academy of Sciences of the United States of America, 2019.
  41. Lee EY, Zhang C, Di Domizio J, Jin F, Connell W, Hung M, Malkoff N, Veksler V, Gilliet M, Ren P, Wong GCL. Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9.. Nature communications, 2019.
  42. Lee MW, Lee EY, Ferguson AL, Wong GCL. Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly.. Current opinion in colloid & interface science, 2018.
  43. Lee MW, Lee EY, Wong GCL. What Can Pleiotropic Proteins in Innate Immunity Teach Us about Bioconjugation and Molecular Design?. Bioconjugate chemistry, 2018.
  44. Lee CK, de Anda J, Baker AE, Bennett RR, Luo Y, Lee EY, Keefe JA, Helali JS, Ma J, Zhao K, Golestanian R, O'Toole GA, Wong GCL. Multigenerational memory and adaptive adhesion in early bacterial biofilm communities.. Proceedings of the National Academy of Sciences of the United States of America, 2018.
  45. Takahashi T, Kulkarni NN, Lee EY, Zhang LJ, Wong GCL, Gallo RL. Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors.. Scientific reports, 2018.
  46. Lee EY, Lee MW, Wong GCL. Modulation of toll-like receptor signaling by antimicrobial peptides.. Seminars in cell & developmental biology, 2018.
  47. Lee MW, Lee EY, Lai GH, Kennedy NW, Posey AE, Xian W, Ferguson AL, Hill RB, Wong GCL. Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission.. ACS central science, 2017.
  48. Lee EY, Lee MW, Fulan BM, Ferguson AL, Wong GCL. What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?. Interface focus, 2017.
  49. Lee EY, Takahashi T, Curk T, Dobnikar J, Gallo RL, Wong GCL. Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation.. ACS nano, 2017.
  50. de Anda J, Lee EY, Lee CK, Bennett RR, Ji X, Soltani S, Harrison MC, Baker AE, Luo Y, Chou T, O'Toole GA, Armani AM, Golestanian R, Wong GCL. High-Speed "4D" Computational Microscopy of Bacterial Surface Motility.. ACS nano, 2017.
  51. Lee EY, Wong GCL, Ferguson AL. Machine learning-enabled discovery and design of membrane-active peptides.. Bioorganic & medicinal chemistry, 2017.
  52. Stolzenberg E, Berry D, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA. A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity.. Journal of innate immunity, 2017.
  53. Tursi SA, Lee EY, Medeiros NJ, Lee MH, Nicastro LK, Buttaro B, Gallucci S, Wilson RP, Wong GCL, Tükel Ç. Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9.. PLoS pathogens, 2017.
  54. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM. Direct Antimicrobial Activity of IFN-β.. Journal of immunology (Baltimore, Md. : 1950), 2017.
  55. Brill-Karniely Y, Jin F, Wong GC, Frenkel D, Dobnikar J. Emergence of complex behavior in pili-based motility in early stages of P. aeruginosa surface adaptation.. Scientific reports, 2017.
  56. Lee MW, Han M, Bossa GV, Snell C, Song Z, Tang H, Yin L, Cheng J, May S, Luijten E, Wong GC. Interactions between Membranes and "Metaphilic" Polypeptide Architectures with Diverse Side-Chain Populations.. ACS nano, 2017.
  57. Deshayes S, Xian W, Schmidt NW, Kordbacheh S, Lieng J, Wang J, Zarmer S, Germain SS, Voyen L, Thulin J, Wong GC, Kasko AM. Designing Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes.. Bioconjugate chemistry, 2017.
  58. Lee EY, Fulan BM, Wong GC, Ferguson AL. Mapping membrane activity in undiscovered peptide sequence space using machine learning.. Proceedings of the National Academy of Sciences of the United States of America, 2016.
  59. Ding M, Shiu HY, Li SL, Lee CK, Wang G, Wu H, Weiss NO, Young TD, Weiss PS, Wong GC, Nealson KH, Huang Y, Duan X. Nanoelectronic Investigation Reveals the Electrochemical Basis of Electrical Conductivity in Shewanella and Geobacter.. ACS nano, 2016.
  60. Gelimson A, Zhao K, Lee CK, Kranz WT, Wong GC, Golestanian R. Multicellular Self-Organization of P. aeruginosa due to Interactions with Secreted Trails.. Physical review letters, 2016.
  61. Lee CK, Kim AJ, Santos GS, Lai PY, Lee SY, Qiao DF, Anda J, Young TD, Chen Y, Rowe AR, Nealson KH, Weiss PS, Wong GCL. Evolution of Cell Size Homeostasis and Growth Rate Diversity during Initial Surface Colonization of Shewanella oneidensis.. ACS nano, 2016.
  62. Kranz WT, Gelimson A, Zhao K, Wong GC, Golestanian R. Effective Dynamics of Microorganisms That Interact with Their Own Trail.. Physical review letters, 2016.
  63. Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages.. PLoS pathogens, 2016.
  64. Wong GC. Three-dimensional architecture of Vibrio cholera biofilms.. Proceedings of the National Academy of Sciences of the United States of America, 2016.
  65. Sankhagowit S, Lee EY, Wong GC, Malmstadt N. Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures.. Langmuir : the ACS journal of surfaces and colloids, 2016.
  66. Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GCL. A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes.. Advances in colloid and interface science, 2016.
  67. Bennett RR, Lee CK, De Anda J, Nealson KH, Yildiz FH, O'Toole GA, Wong GC, Golestanian R. Species-dependent hydrodynamics of flagellum-tethered bacteria in early biofilm development.. Journal of the Royal Society, Interface, 2016.
  68. Hu W, Gibiansky ML, Wang J, Wang C, Lux R, Li Y, Wong GC, Shi W. Interplay between type IV pili activity and exopolysaccharides secretion controls motility patterns in single cells of Myxococcus xanthus.. Scientific reports, 2016.
  69. Biteen JS, Blainey PC, Cardon ZG, Chun M, Church GM, Dorrestein PC, Fraser SE, Gilbert JA, Jansson JK, Knight R, Miller JF, Ozcan A, Prather KA, Quake SR, Ruby EG, Silver PA, Taha S, van den Engh G, Weiss PS, Wong GC, Wright AT, Young TD. Tools for the Microbiome: Nano and Beyond.. ACS nano, 2015.
  70. Jones CJ, Utada A, Davis KR, Thongsomboon W, Zamorano Sanchez D, Banakar V, Cegelski L, Wong GC, Yildiz FH. C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae.. PLoS pathogens, 2015.
  71. Maier B, Wong GCL. How Bacteria Use Type IV Pili Machinery on Surfaces.. Trends in microbiology, 2015.
  72. Xiong M, Lee MW, Mansbach RA, Song Z, Bao Y, Peek RM, Yao C, Chen LF, Ferguson AL, Wong GC, Cheng J. Helical antimicrobial polypeptides with radial amphiphilicity.. Proceedings of the National Academy of Sciences of the United States of America, 2015.
  73. Yao H, Lee MW, Waring AJ, Wong GC, Hong M. Viral fusion protein transmembrane domain adopts β-strand structure to facilitate membrane topological changes for virus-cell fusion.. Proceedings of the National Academy of Sciences of the United States of America, 2015.
  74. Schmidt NW, Jin F, Lande R, Curk T, Xian W, Lee C, Frasca L, Frenkel D, Dobnikar J, Gilliet M, Wong GC. Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation.. Nature materials, 2015.
  75. Teschler JK, Zamorano-Sánchez D, Utada AS, Warner CJ, Wong GC, Linington RG, Yildiz FH. Living in the matrix: assembly and control of Vibrio cholerae biofilms.. Nature reviews. Microbiology, 2015.
  76. Kramer JR, Schmidt NW, Mayle KM, Kamei DT, Wong GC, Deming TJ. Reinventing Cell Penetrating Peptides Using Glycosylated Methionine Sulfonium Ion Sequences.. ACS central science, 2015.
  77. Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL. Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes.. The Journal of investigative dermatology, 2015.
  78. Luo Y, Zhao K, Baker AE, Kuchma SL, Coggan KA, Wolfgang MC, Wong GC, O'Toole GA. A hierarchical cascade of second messengers regulates Pseudomonas aeruginosa surface behaviors.. mBio, 2015.
  79. Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH. Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits.. Journal of the American Chemical Society, 2014.
  80. Utada AS, Bennett RR, Fong JCN, Gibiansky ML, Yildiz FH, Golestanian R, Wong GCL. Vibrio cholerae use pili and flagella synergistically to effect motility switching and conditional surface attachment.. Nature communications, 2014.
  81. Schmidt NW, Deshayes S, Hawker S, Blacker A, Kasko AM, Wong GC. Engineering persister-specific antibiotics with synergistic antimicrobial functions.. ACS nano, 2014.
  82. Lee MW, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides.. Biochimica et biophysica acta, 2014.
  83. Schmidt NW, Mishra A, Wang J, DeGrado WF, Wong GC. Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission.. Journal of the American Chemical Society, 2013.
  84. Schmidt NW, Wong GC. Antimicrobial peptides and induced membrane curvature: geometry, coordination chemistry, and molecular engineering.. Current opinion in solid state & materials science, 2013.
  85. Zhao K, Tseng BS, Beckerman B, Jin F, Gibiansky ML, Harrison JJ, Luijten E, Parsek MR, Wong GCL. Psl trails guide exploration and microcolony formation in Pseudomonas aeruginosa biofilms.. Nature, 2013.
  86. Gibiansky ML, Hu W, Dahmen KA, Shi W, Wong GC. Earthquake-like dynamics in Myxococcus xanthus social motility.. Proceedings of the National Academy of Sciences of the United States of America, 2013.
  87. Hu K, Schmidt NW, Zhu R, Jiang Y, Lai GH, Wei G, Palermo EF, Kuroda K, Wong GC, Yang L. A critical evaluation of random copolymer mimesis of homogeneous antimicrobial peptides.. Macromolecules, 2013.
  88. Schmidt NW, Lis M, Zhao K, Lai GH, Alexandrova AN, Tew GN, Wong GC. Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences.. Journal of the American Chemical Society, 2012.
  89. Schmidt NW, Tai KP, Kamdar K, Mishra A, Lai GH, Zhao K, Ouellette AJ, Wong GC. Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior.. The Journal of biological chemistry, 2012.
  90. Coridan RH, Schmidt NW, Lai GH, Abbamonte P, Wong GC. Dynamics of confined water reconstructed from inelastic x-ray scattering measurements of bulk response functions.. Physical review. E, Statistical, nonlinear, and soft matter physics, 2012.
  91. Zhao K, Choe UJ, Kamei DT, Wong GC. Enhanced activity of cyclic transporter sequences driven by phase behavior of peptide-lipid complexes.. Soft matter, 2012.
  92. Mishra A, Lai GH, Schmidt NW, Sun VZ, Rodriguez AR, Tong R, Tang L, Cheng J, Deming TJ, Kamei DT, Wong GC. Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
  93. Zasloff M, Adams AP, Beckerman B, Campbell A, Han Z, Luijten E, Meza I, Julander J, Mishra A, Qu W, Taylor JM, Weaver SC, Wong GC. Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
  94. Jin F, Conrad JC, Gibiansky ML, Wong GC. Bacteria use type-IV pili to slingshot on surfaces.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
  95. Wong GC, O'Toole GA. All together now: Integrating biofilm research across disciplines.. MRS bulletin, 2011.
  96. Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC. Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization.. Journal of the American Chemical Society, 2011.
  97. Conrad JC, Gibiansky ML, Jin F, Gordon VD, Motto DA, Mathewson MA, Stopka WG, Zelasko DC, Shrout JD, Wong GC. Flagella and pili-mediated near-surface single-cell motility mechanisms in P. aeruginosa.. Biophysical journal, 2011.
  98. Colvin KM, Gordon VD, Murakami K, Borlee BR, Wozniak DJ, Wong GC, Parsek MR. The pel polysaccharide can serve a structural and protective role in the biofilm matrix of Pseudomonas aeruginosa.. PLoS pathogens, 2011.
  99. Mishra A, Tai KP, Schmidt NW, Ouellette AJ, Wong GC. Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell α-defensin cryptdin-4.. Methods in enzymology, 2011.
  100. Gibiansky ML, Conrad JC, Jin F, Gordon VD, Motto DA, Mathewson MA, Stopka WG, Zelasko DC, Shrout JD, Wong GC. Bacteria use type IV pili to walk upright and detach from surfaces.. Science (New York, N.Y.), 2010.
  101. Abbamonte P, Wong GC, Cahill DG, Reed JP, Coridan RH, Schmidt NW, Lai GH, Joe YI, Casa D. Ultrafast imaging and the phase problem for inelastic X-ray scattering.. Advanced materials (Deerfield Beach, Fla.), 2010.
  102. Mylon SE, Rinciog CI, Schmidt N, Gutierrez L, Wong GC, Nguyen TH. Influence of salts and natural organic matter on the stability of bacteriophage MS2.. Langmuir : the ACS journal of surfaces and colloids, 2010.
  103. Coridan RH, Schmidt NW, Lai GH, Godawat R, Krisch M, Garde S, Abbamonte P, Wong GC. Hydration dynamics at femtosecond time scales and angstrom length scales from inelastic x-ray scattering.. Physical review letters, 2009.
  104. Schmidt N, Mishra A, Lai GH, Wong GC. Arginine-rich cell-penetrating peptides.. FEBS letters, 2009.
  105. Som A, Yang L, Wong GC, Tew GN. Divalent metal ion triggered activity of a synthetic antimicrobial in cardiolipin membranes.. Journal of the American Chemical Society, 2009.
  106. Coridan RH, Schmidt NW, Lai GH, Wong GC. Hydration structures near finite-sized nanoscopic objects reconstructed using inelastic x-ray scattering measurements.. Journal of physics. Condensed matter : an Institute of Physics journal, 2009.
  107. Yigit MV, Mishra A, Tong R, Cheng J, Wong GC, Lu Y. Inorganic mercury detection and controlled release of chelating agents from ion-responsive liposomes.. Chemistry & biology, 2009.
  108. Purdy Drew KR, Sanders LK, Culumber ZW, Zribi O, Wong GC. Cationic amphiphiles increase activity of aminoglycoside antibiotic tobramycin in the presence of airway polyelectrolytes.. Journal of the American Chemical Society, 2009.
  109. Cao Z, Tong R, Mishra A, Xu W, Wong GC, Cheng J, Lu Y. Reversible cell-specific drug delivery with aptamer-functionalized liposomes.. Angewandte Chemie (International ed. in English), 2009.
  110. Yang L, Gordon VD, Trinkle DR, Schmidt NW, Davis MA, DeVries C, Som A, Cronan JE, Tew GN, Wong GC. Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids.. Proceedings of the National Academy of Sciences of the United States of America, 2008.
  111. Lai GH, Butler JC, Zribi OV, Smalyukh II, Angelini TE, Purdy KR, Golestanian R, Wong GC. Self-organized gels in DNA/F-actin mixtures without crosslinkers: networks of induced nematic domains with tunable density.. Physical review letters, 2008.
  112. Smalyukh II, Butler J, Shrout JD, Parsek MR, Wong GC. Elasticity-mediated nematiclike bacterial organization in model extracellular DNA matrix.. Physical review. E, Statistical, nonlinear, and soft matter physics, 2008.
  113. Mishra A, Gordon VD, Yang L, Coridan R, Wong GC. HIV TAT forms pores in membranes by inducing saddle-splay curvature: potential role of bidentate hydrogen bonding.. Angewandte Chemie (International ed. in English), 2008.
  114. Sanders LK, Xian W, Guáqueta C, Strohman MJ, Vrasich CR, Luijten E, Wong GC. Control of electrostatic interactions between F-actin and genetically modified lysozyme in aqueous media.. Proceedings of the National Academy of Sciences of the United States of America, 2007.
  115. Yang L, Gordon VD, Mishra A, Som A, Purdy KR, Davis MA, Tew GN, Wong GC. Synthetic antimicrobial oligomers induce a composition-dependent topological transition in membranes.. Journal of the American Chemical Society, 2007.
  116. Lai GH, Coridan R, Zribi OV, Golestanian R, Wong GC. Evolution of growth modes for polyelectrolyte bundles.. Physical review letters, 2007.
  117. Angelini TE, Golestanian R, Coridan RH, Butler JC, Beraud A, Krisch M, Sinn H, Schweizer KS, Wong GC. Counterions between charged polymers exhibit liquid-like organization and dynamics.. Proceedings of the National Academy of Sciences of the United States of America, 2006.
  118. Smalyukh II, Zribi OV, Butler JC, Lavrentovich OD, Wong GC. Structure and dynamics of liquid crystalline pattern formation in drying droplets of DNA.. Physical review letters, 2006.
  119. Guáqueta C, Sanders LK, Wong GC, Luijten E. The effect of salt on self-assembled actin-lysozyme complexes.. Biophysical journal, 2006.
  120. Zribi OV, Kyung H, Golestanian R, Liverpool TB, Wong GC. Condensation of DNA-actin polyelectrolyte mixtures driven by ions of different valences.. Physical review. E, Statistical, nonlinear, and soft matter physics, 2006.
  121. Sanders LK, Guáqueta C, Angelini TE, Lee JW, Slimmer SC, Luijten E, Wong GC. Structure and stability of self-assembled actin-lysozyme complexes in salty water.. Physical review letters, 2005.
  122. Liang H, Angelini TE, Braun PV, Wong GC. Roles of anionic and cationic template components in biomineralization of CdS nanorods using self-assembled DNA-membrane complexes.. Journal of the American Chemical Society, 2004.
  123. Yang L, Liang H, Angelini TE, Butler J, Coridan R, Tang JX, Wong GC. Self-assembled virus-membrane complexes.. Nature materials, 2004.
  124. Liang H, Angelini TE, Ho J, Braun PV, Wong GC. Molecular imprinting of biomineralized CdS nanostructures: crystallographic control using self-assembled DNA-membrane templates.. Journal of the American Chemical Society, 2003.
  125. Butler JC, Angelini T, Tang JX, Wong GC. Ion multivalence and like-charge polyelectrolyte attraction.. Physical review letters, 2003.
  126. Angelini TE, Liang H, Wriggers W, Wong GC. Like-charge attraction between polyelectrolytes induced by counterion charge density waves.. Proceedings of the National Academy of Sciences of the United States of America, 2003.