Harley Kornblum

Harley I Kornblum

Professor-in-Residence, Psychiatry and Biobehavioral Sciences, University of California Los Angeles

Professor-in-Residence, Pediatrics, University of California Los Angeles

Professor-in-Residence, Molecular and Medical Pharmacology, University of California Los Angeles

Laboratory Address:
635 Charles E. Young Drive South
Los Angeles, CA 90095

Office Address:
Room 341 NRB
635 Charles E. Young Drive south
Los Angeles, CA 90095

Work Email Address:

Work Phone Number:
(310) 794-7866


Member, Brain Research Institute, Cell & Developmental Biology GPB Home Area, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, JCCC Cancer and Stem Cell Biology Program Area, Molecular Pharmacology GPB Home Area, Molecular, Cellular & Integrative Physiology GPB Home Area, Neuroscience GPB Home Area

Research Interests

Dr. Kornblum’s laboratory works in the areas of neurodevelopment, neural repair and brain tumors. His work investigates the factors that drive these processes. He is one of the co-discoverers of stem cell-like cells in brain tumors. These cells are thought to be critical means by which brain tumors resist therapies. Dr. Kornblum’s laboratory is investigating a number of means to overcome this therapeutic resistance. In addition to brain tumors, Dr. Kornblum’s research is relevant to the areas of autism, spinal cord injury, stroke and cerebral palsy, as well as other developmental disorders of the nervous system.


Dr. Kornblum is a basic and translational researcher in the Intellectual and Developmental Disabilities Research Center of the Semel Research Institute. He is Professor of Psychiatry, Pharmacology and Pediatrics at the David Geffen School of Medicine at UCLA. He is also an attending Pediatric Neurologist at Mattel Children’s Hospital at UCLA and the founding director of the Neural Stem Cell Research Center. He is a member of the Brain Research Institute, The Broad Stem Cell Research Center and the Molecular Biology Institute and serves on the Steering Committe of the Broad Stem Cell Research Center. Dr. Kornblum received his AB degree from Washington University in St. Louis and his MD and PhD degrees from UC Irvine. He trained as a Pediatrics Resident and Pediatric Neurology Fellow at UCLA. He did undergraduate research with Dr. Eugene M. Johnson and received his PhD in the laboratory of Frances M. Leslie. He pursued postdoctoral research with Dr. Christine M. Gall at UCI and Dr. Harry Chugani at UCLA. Dr. Kornblum is a frequent lecturer on the topics of neural stem cells and brain tumors at conferences and universities world-wide and has published over 100 research articles and book chapters. Dr. Kornblum is the recipient of numerous grants from the Federal Government as well as philanthropic foundations. He served as the Eleanor Leslie Professor of Pioneering Brain Research.