silhouette of a female

Jeanette C. Papp *


Gonda Center
695 Charles E. Young Drive South
Los Angeles, CA 90095


Bioinformatics in Human Genetics
Dr. Papp is a member of the UCLA Bioinformatics Core. She came to UCLA in 2000. Prior to that she worked at genome centers in Paris and Oxford. In addition to overseeing data generation and analysis in the Core, her research interests include developing novel bioinformatic solutions for the management and analysis of all types of genetic data within the Department of Human Genetics.


A selected list of publications:
  • Lange K, Papp JC, Sinsheimer JS, Sobel EM   Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data, Annu. Rev. Stat. Appl, 2014; 1: 279–300.
  • Yang T, Chang P, Park SL, Bastani D, Chang S-C, Morgenstern H, Tashkin DP, Mao JT, Papp JC, Rao J-Y, Cozen W, Mack TM, Greenland S, Zhang ZF   Tobacco smoking, NBS1 polymorphisms, and survival in lung and upper aerodigestive tract cancers with semi-Bayes adjustment for hazard ratio variation, Cancer Causes Control, 2014; 25(1): 11-23.
  • Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM   Mendel: the Swiss army knife of genetic analysis programs, Bioinformatics, 2013; 29(12): 1568-70.
  • Van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ   The systems genetics resource: a web application to mine global data for complex disease traits, Front. Genet, 2013; 4(84): .
  • Scofield, DG, Alfaro VR, Sork VL, Grivet D, Martinez E, Papp J, Pluess AR, Koenig WD, Smouse PE.   Foraging patterns of acorn woodpeckers (Melanerpes formicivorus) on valley oak (Quercus lobata Née) in two California oak savanna-woodlands, Oecologia , 2011; 166(1): 187-196.
  • Zhong M, Lange K, Papp JC, and Ruzong Fan R.   A Powerful Score Test to Detect Positive Selection in Genome-wide Scans, Eur J Hum Genet, 2010; 18(10): 1148-59.
  • Park SL, Bastani D, Goldstein BY, Chang SC, Cozen W, Cai L, Cordon-Cardo C, Ding B, Greenland S, He N, Hussain SK, Jiang Q, Lee YCA, Liu S, Lu ML, Mack TM, Mao JT, Morgenstern H,Mu LN, Oh SS, Pantuck A, Papp JC, Rao J, Reuter VE, Tashkin DP, Wang H,Wang YR, You NCY, Yu SZ, Zhao JK, Zhang ZF.   Associations between NBS1 polymorphisms, haplotypes, and smoking-related cancers, Carcinogenesis, 2010; 7: 1264-71.
  • Aldave AJ, Rosenwasser GOD, Yellore VS, Papp JC, Sobel EM, Pham MN, Chen MC, Dandekar S, Sripracha R, Rayner SA, Sassani JW, Gorin MB.   Linkage of Posterior Amorphous Corneal Dystrophy to Chromosome 12q21.33 and Exclusion of Coding Region Mutations in KERA, LUM, DCN, and EPYC, Invest Ophthalmol Vis Sci, 2010; 51(18): 4006-12.
  • Oh SS, Chang SC, Cai L, Cordon-Cardo C, Ding BG, Greenland S, He N, Jiang Q, Kheifets L, Le A, Lee YC, Liu S, Lu ML, Mao JT, Morgenstern H, Mu1 LN, Pantuck A, Papp JC, Park SL, Rao JY, Reuter VE, Tashkin DP, Wang H, You NC, Yu SZ, Zhao JK, Belldegrun A, Zhang ZF.   Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers, Int J Cancer, 2010; 127(9): 2169-82.
  • Anderson SL, Chung WK, Frezzo J, Papp JC, Ekstein J, Dimauro S, Rubin BY.   A novel mutation in NDUFS4 causes Leigh syndrome in an Ashkenazi Jewish family, J Inherit Metab Dis. , 2009; Suppl 2: S461-7.
  • Zhou JJ, Lange K, Papp JC, Sinsheimer JS   A Heterozygote-Homozygote Test of Hardy-Weinberg Equilibrium, Eur J Hum Genet , 2009; 17(11): 1495-1500.
  • Sehl ME, Langer LR, Papp JC, Kwan L, Seldon JL, Arellano G, Reiss J, Reed EF, Dandekar S, Korin Y, Sinsheimer JS, Zhang ZF, Ganz PA.   Associations between Single Nucleotide Polymorphisms in Double-Stranded DNA Repair Pathway Genes and Familial Breast Cancer, Clin Cancer Res, 2009; 15: 2192-2203.
  • Levine AJ, Singer EJ, Sinsheimer JS, Hinkin CH, Papp J, Dandekar S, Giovanelli A, Shapshak P   CCL3 genotype and current depression increase risk of HIV-associated dementia, Neurobehavioral HIV Medicine, 2009; 1: 1-7.
  • Levine AJ, Singer EJ, Sinsheimer JS, Hinkin CH, Papp J, Dandekar S, Giovanelli A, Shapshak P   CCL3 genotype and current depression increase risk of HIV-associated dementia, Neurobehavioral HIV Medicine, 2009; 1: 1-7.
  • Aldave AJ, Yellore VS, Vo RC, Kamal KM, Rayner SA, Plaisier CL, Chen MC, Damani MR, Pham MN, Gorin MB, Sobel ES, Papp JC   Exclusion of Positional Candidate Gene Coding Region Mutations in the Common Posterior Polymorphous Corneal Dystrophy 1 Candidate Gene Interval, Cornea , 2009; 28(7): 801-807.
  • Hussain SK, Mu LN, Cai L, Chang SC, Park SL, Oh SS, Wang Y, Goldstein BY, Ding BG, Jiang Q, Rao J, You NC, Yu SZ, Papp JC, Zhao JK, Wang H, Zhang ZF   Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China, Cancer Epidemiol Biomarkers Prev, 2009; 18(8): 2304-2309.
  • Pluess AR, Sork VL, Dolan B, Davis FW, Grivet D, Merg K, Papp J, Smouse PE   Short distance pollen movement in a wind-pollinated tree, Quercus lobata (Fagaceae), Forest Ecology and Management , 2009; 258: 735-744.
  • Presson AP, Sobel EM, Pajukanta P, Plaisier C, Weeks DE, Aberg K, Papp JC.   Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis, BMC Bioinformatics, 2008; 9: 317.
  • Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF.   A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers, Int J Cancer, 2008; 122(7): 1630-1638.
  • Arumugaswami V, Sitapara R, Hwang S, Song MJ, Ho TN, Su NQ, Sue EY, Kanagavel V, Xing F, Zhang X, Zhao M, Deng H, Wu T, Kanagavel S, Zhang L, Dandekar S, Papp J, Sun R.   High-resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome, J Virol, 2008; 83: 1811.
  • Presson AP, Sobel EM, Papp JC, Suarez CJ, Whistler T, Rajeevan MS, Vernon SD, Horvath S.   Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome, BMC Systems Biology, 2008; 2: 95.
  • Aldave AJ, Sonmez B, Bourla N, Schultz G, Papp JC, Salem AK, Rayner SA, Yellore VS.   Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2, Ophthalmic Genet, 2007; 28: 57-67.
  • Yellore VS, Papp J, Sobel E, Khan MA, Rayner SA, Farber DB, Aldave AJ.   Replication and Refinement of Linkage of Posterior Polymorphous Corneal Dystrophy to the PPCD1 Locus on Chromosome 20, Genetics in Medicine, 2007; 9: 228-234.
  • Presson A, Sobel E, Lange, K. Papp JC.   Merging Microsatellite Data, Journal of Computational Biology, 2006; 13: 1131-1147.
  • Kaunisto MA, Tikka PJ, Kallela M, Leal SM, Papp JC, Korhonen A, Hamalainen E, Harno H, Havanka H, Nissila M, Sako E, Ilmavirta M, Kaprio J, Farkkila M, Ophoff RA, Palotie A, Wessman M.   Chromosome 19p13 loci in Finnish migraine with aura families , Am J Med Genet B Neuropsychiatr Genet, 2005; 132B(1): 85-89.
  • Caulfield Mark, Munroe Patricia, Pembroke Janine, Samani Nilesh, Dominiczak Anna, Brown Morris, Benjamin Nigel, Webster John, Ratcliffe Peter, O’Shea Suzanne, Papp Jeanette, Taylor Elizabeth, Dobson Richard, Knight Joanne, Newhouse Stephen, Hooper Joel, Lee Wai, Brain Nick, Clayton David, Lathrop G Mark, Farrall Martin, Connell John, Connell John   Genome-wide mapping of human loci for essential hypertension Lancet, 2003; 361(9375): 2118-23.
  • Novak U, Oppliger Leibundgut E, Hager J, Muhlematter D, Jotterand M, Besse C, Leupin N, Ratschiller D, Papp J, Kearsey G, Aebi S, Graber H, Jaggi R, Luthi JM, Meyer-Monard S, Lathrop M, Tobler A, Fey MF.   A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL) Blood, 2002; 100(5): 1787-94.
  • Wessman M, Kallela M, Kaunisto MA, Marttila P, Sobel E, Hartiala J, Oswell G, Leal SM, Papp JC, Hamalainen E, Broas P, Joslyn G, Hovatta I, Hiekkalinna T, Kaprio J, Ott J, Cantor RM, Zwart JA, Ilmavirta M, Havanka H, Farkkila M, Peltonen L, Palotie A.   A susceptibility locus for migraine with aura, on chromosome 4q24, Am J Hum Genet, 2002; 70(3): 652-62.
  • Sobel E, Papp JC, Lange K   Detection and integration of genotyping errors in statistical genetics Am J Hum Genet, 2002; 70(2): 496-508.
  • Holm P, Senee V, Julier C, Kockum I, Blanc H, Papp J, Bartsocas C, Dahlquist G, Mato E, de Leiva A, Lathrop M, Luthman H, Nerup J, Pociot F, Ranningen K, Akesson K   A genome-wide scan for type 1-diabetes susceptibility genes in Scandinavian families: Identification of new loci with evidence of interactions, Am J Hum Genet, 2001; 69: 1301-1313.
  • Gedde-Dahl T, Delpine M, Khallouf E, Van Maldergem L, Sobel E, Papp J, Meier M, Mégarbané A, Lathrop M, Capeau J, Magré J   Congenital lipodystrophy Berardinelli-Seip reveals a new gene and a new protein, Journal of Investigative Dermatology , 2001; 117: 1678.
  • Magre J, Delepine M, Khallouf E, Gedde-Dahl T Jr, Van Maldergem L, Sobel E, Papp J, Meier M, Megarbane A, Bachy A, Verloes A, d’Abronzo FH, Seemanova E, Assan R, Baudic N, Bourut C, Czernichow P, Huet F, Grigorescu F, de Kerdanet M, Lacombe D, Labrun.   Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13, Nature Genetics, 2001; 28(4): 365 – 370.