Jeffrey Abramson

Jeffrey S Abramson

Professor, Physiology, University of California Los Angeles

310-825-3913

Laboratory Address:
CHS 53-254

Work Address:
CHS 53-260
Mailcode 775118

Fax Number:
310-206-5661

Affiliations

Member, Biochemistry, Biophysics & Structural Biology GPB Home Area, I3T Theme, Molecular, Cellular & Integrative Physiology GPB Home Area
 

Research Interests

At least 20% of the genomes sequenced thus far encode for membrane proteins. Many of these proteins are involved in fundamental biological processes and have been linked with numerous human diseases, thus they are often primary targets for therapeutic drugs. However, the number of crystal structures of membrane proteins is very limited considering their vast numbers as well as crucial biological and medical relevance. We are attempting to expedite structural determination of membrane proteins by utilizing robotics for crystallization as well as visualization in order to increase throughput of membrane protein structures. The laboratory is focused on several membrane transport proteins with the goal of developing a detailed understanding of the mechanisms involved in these transport processes by utilizing the structure in conjunction with a biochemical and biophysical techniques.
 

Biography:

Jeff Abramson has recently joined the faculty of UCLA in January of 2005. Although his primary training is in Biochemistry and Structural Biology he was recruited by the Department of Physiology. Dr. Abramson earned his B.S. in Biotechnology at California Polytechnic University Pomona and his Ph.D. in Biochemistry at Uppsala University, Sweden. He then went to Imperial College London for his postdoctoral training where he furthered his skills in membrane protein crystallography. Dr. Abramson is currently collaborating with a number of groups within the Department of Physiology where he is utilizing robotics for crystallization as well as visualization in order to increase throughput of membrane protein structures.

Publications