Publications

1. Du W, Verma A, Ye Q, Du W, Lin S, Yamanaka A, Klein OD, Hu JK. Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement.. PLoS genetics, 2024.
2. Shroff NP, Xu P, Kim S, Shelton ER, Gross BJ, Liu Y, Gomez CO, Ye Q, Drennon TY, Hu JK, Green JBA, Campàs O, Klein OD. Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development.. Nature cell biology, 2024.
3. Sundari Thooyamani A, Shahin E, Takano S, Sharir A, Hu JK. Using Ex Vivo Live Imaging to Investigate Cell Divisions and Movements During Mouse Dental Renewal.. Journal of visualized experiments : JoVE, 2023.
4. Hu JK. Nail mesenchyme: Tipping the hand on regeneration.. Cell reports, 2023.
5. Ye Q, Bhojwani A, Hu JK. Understanding the development of oral epithelial organs through single cell transcriptomic analysis.. Development (Cambridge, England), 2022.
6. Du W, Bhojwani A, Hu JK. FACEts of mechanical regulation in the morphogenesis of craniofacial structures.. International journal of oral science, 2021.
7. Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.. Science translational medicine, 2020.
8. Kindberg A, Hu JK, Bush JO. Forced to communicate: Integration of mechanical and biochemical signaling in morphogenesis.. Current opinion in cell biology, 2020.
9. Sharir A, Marangoni P, Zilionis R, Wan M, Wald T, Hu JK, Kawaguchi K, Castillo-Azofeifa D, Epstein L, Harrington K, Pagella P, Mitsiadis T, Siebel CW, Klein AM, Klein OD. A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.. Nature cell biology, 2019.
10. Calamari ZT, Hu JK, Klein OD. Tissue Mechanical Forces and Evolutionary Developmental Changes Act Through Space and Time to Shape Tooth Morphology and Function.. BioEssays : news and reviews in molecular, cellular and developmental biology, 2018.
11. Du W, Hu JK, Du W, Klein OD. Lineage tracing of epithelial cells in developing teeth reveals two strategies for building signaling centers.. The Journal of biological chemistry, 2017.
12. Hu JK, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.. Cell stem cell, 2017.
13. Tschopp P, Sherratt E, Sanger TJ, Groner AC, Aspiras AC, Hu JK, Pourquié O, Gros J, Tabin CJ. A relative shift in cloacal location repositions external genitalia in amniote evolution.. Nature, 2014.
14. Biehs B, Hu JK, Strauli NB, Sangiorgi E, Jung H, Heber RP, Ho S, Goodwin AF, Dasen JS, Capecchi MR, Klein OD. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor.. Nature cell biology, 2013.
15. Hu JK, McGlinn E, Harfe BD, Kardon G, Tabin CJ. Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.. Genes & development, 2012.
16. Cooper KL, Hu JK, ten Berge D, Fernandez-Teran M, Ros MA, Tabin CJ. Initiation of proximal-distal patterning in the vertebrate limb by signals and growth.. Science (New York, N.Y.), 2011.
17. Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ. WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud.. Current biology : CB, 2010.
18. Schlabach MR, Hu JK, Li M, Elledge SJ. Synthetic design of strong promoters.. Proceedings of the National Academy of Sciences of the United States of America, 2010.
19. Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ. Temporomandibular joint formation requires two distinct hedgehog-dependent steps.. Proceedings of the National Academy of Sciences of the United States of America, 2009.
20. Loscertales M, Mikels AJ, Hu JK, Donahoe PK, Roberts DJ. Chick pulmonary Wnt5a directs airway and vascular tubulogenesis.. Development (Cambridge, England), 2008.
21. Horsfield JA, Anagnostou SH, Hu JK, Cho KH, Geisler R, Lieschke G, Crosier KE, Crosier PS. Cohesin-dependent regulation of Runx genes.. Development (Cambridge, England), 2007.
22. Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development.. Nature, 2005.