Publications

1. Kilpatrick LA, Church A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer EA. Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals.. Biology of sex differences, 2025.
2. Aziz-Zadeh L, Ringold SM, Jayashankar A, Kilroy E, Butera C, Jacobs JP, Tanartkit S, Mahurkar-Joshi S, Bhatt RR, Dapretto M, Labus JS, Mayer EA. Relationships between brain activity, tryptophan-related gut metabolites, and autism symptomatology.. Nature communications, 2025.
3. Li VW, Dong TS, Funes D, Hernandez L, Kushnir NR, Nair D, Jacobs JP, Reddy ST, Mayer EA, Chang L, Meriwether D. Mass spectrometric profiling of primary estrogens and estrogen metabolites in human stool and plasma partially elucidates the role of the gut microbiome in estrogen recycling.. Molecular and cellular endocrinology, 2025.
4. Xie Y, Irwin S, Nelson B, van Daelen M, Fontenot L, Jacobs JP, Cappelletti M, Feng H, Li Y, Koon HW. Citrulline Inhibits Clostridioides difficile Infection With Anti-inflammatory Effects.. Cellular and molecular gastroenterology and hepatology, 2025.
5. Aja E, Zeng A, Gray W, Connelley K, Chaganti A, Jacobs JP. Health Effects and Therapeutic Potential of the Gut Microbe Akkermansia muciniphila.. Nutrients, 2025.
6. Yang HH, Simpson CA, Srivastava M, Bera A, Cappelletti M, Suh JD, Wang MB, Beswick DM, Maxim T, Basak SK, Srivatsan ES, Fischer JL, Jacobs JP, Lee JT. Biodiversity of the Bacterial and Fungal Microbiome and Associated Inflammatory Cytokine Profile in Chronic Rhinosinusitis.. International forum of allergy & rhinology, 2025.
7. Yang JC, Lagishetty V, Aja E, Arias-Jayo N, Chang C, Hauer M, Katzka W, Zhou Y, Sedighian F, Koletic C, Liang F, Dong TS, Situ J, Troutman R, Buri H, Bhute S, Simpson CA, Braun J, Jacob N, Jacobs JP. Biogeographical distribution of gut microbiome composition and function is partially recapitulated by fecal transplantation into germ-free mice.. The ISME journal, 2025.
8. Yang J, Lei OK, Bhute S, Kris-Etherton PM, Lichtenstein AH, Matthan NR, Petersen KS, Sabaté J, Reboussin DM, Lovato L, Vitolins MZ, Rajaram S, Jacobs JP, Huang J, Taw M, Yang S, Li Z. Impact of daily avocado consumption on gut microbiota in adults with abdominal obesity: an ancillary study of HAT, a randomized controlled trial.. Food & function, 2025.
9. Jacobs JP, Spencer EA, Helmus DS, Yang JC, Lagishetty V, Bongers G, Britton G, Gettler K, Reyes-Mercedes P, Hu J, Hart A, Lamousé-Smith E, Wehkamp J, Landers C, Debbas P, Torres J, Colombel JF, Cho J, Peter I, Faith J, Braun J, Dubinsky M. Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families.. Gut, 2024.
10. Yang JC, Zhao M, Chernikova D, Arias-Jayo N, Zhou Y, Situ J, Gutta A, Chang C, Liang F, Lagishetty V, Jacobs JP. ZIP8 A391T Crohn's Disease-Linked Risk Variant Induces Colonic Metal Ion Dyshomeostasis, Microbiome Compositional Shifts, and Inflammation.. Digestive diseases and sciences, 2024.
11. Kilpatrick LA, Gupta A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer EA. Differential brainstem connectivity according to sex and menopausal status in healthy men and women.. Research square, 2024.
12. Shera S, Katzka W, Yang JC, Chang C, Arias-Jayo N, Lagishetty V, Balioukova A, Chen Y, Dutson E, Li Z, Mayer EA, Pisegna JR, Sanmiguel C, Pawar S, Zhang D, Leitman M, Hernandez L, Jacobs JP, Dong TS. Bariatric-induced microbiome changes alter MASLD development in association with changes in the innate immune system.. Frontiers in microbiology, 2024.
13. Mahurkar-Joshi S, Shera S, Labus J, Dong TS, Jacobs JP, Chang L. Sex Differences in Colonic Mucosal Microbiome of Irritable Bowel Syndrome Patients Compared to Healthy Controls.. medRxiv : the preprint server for health sciences, 2024.
14. Dong TS, Peters K, Gupta A, Jacobs JP, UCLA SCORE Group in IBS and Sex Differences, Chang L. Prevotella Is Associated With Sex-Based Differences in Irritable Bowel Syndrome.. Gastroenterology, 2024.
15. Aja E, Jacobs JP. Mommy's microbes: Gestational diabetes mellitus shapes the maternal and infant gut microbiome.. Cell host & microbe, 2024.
16. Chang C, Louie A, Zhou Y, Gupta R, Liang F, Xanthou G, Ereso J, Koletic C, Yang JC, Sedighian F, Lagishetty V, Arias-Jayo N, Altuwayjiri A, Tohidi R, Navab M, Reddy ST, Sioutas C, Hsiai T, Araujo JA, Jacobs JP. Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid.. International journal of molecular sciences, 2024.
17. Andréasson K, Olofsson T, Lagishetty V, Alrawi Z, Klaassens E, Holster S, Hesselstrand R, Jacobs JP, Wallman JK, Volkmann ER. Treatment for Rheumatoid Arthritis Associated With Alterations in the Gastrointestinal Microbiota.. ACR open rheumatology, 2024.
18. Kwon D, Zhang K, Paul KC, Folle AD, Del Rosario I, Jacobs JP, Keener AM, Bronstein JM, Ritz B. Diet and the gut microbiome in patients with Parkinson's disease.. NPJ Parkinson's disease, 2024.
19. Zhang K, Paul K, Jacobs JP, Cockburn MG, Bronstein JM, Del Rosario I, Ritz B. Ambient long-term exposure to organophosphorus pesticides and the human gut microbiome: an observational study.. Environmental health : a global access science source, 2024.
20. Ye X, Ghosh S, Shin BC, Ganguly A, Maggiotto L, Jacobs JP, Devaskar SU. Brain serotonin and serotonin transporter expression in male and female postnatal rat offspring in response to perturbed early life dietary exposures.. Frontiers in neuroscience, 2024.
21. Kim MJ, Kim HN, Jacobs JP, Yang HJ. Combined DNA Methylation and Gastric Microbiome Marker Predicts Helicobacter pylori-Negative Gastric Cancer.. Gut and liver, 2024.
22. Jacobs JP, Sauk JS, Ahdoot AI, Liang F, Katzka W, Ryu HJ, Khandadash A, Lagishetty V, Labus JS, Naliboff BD, Mayer EA. Microbial and Metabolite Signatures of Stress Reactivity in Ulcerative Colitis Patients in Clinical Remission Predict Clinical Flare Risk.. Inflammatory bowel diseases, 2024.
23. Gray WR, Jacobs JP. Modulation of Host Physiology and Pathophysiology by the Gut Microbiome.. Nutrients, 2024.
24. Chang C, Gupta R, Sedighian F, Louie A, Gonzalez DM, Le C, Cho JM, Park SK, Castellanos J, Ting TW, Dong TS, Arias-Jayo N, Lagishetty V, Navab M, Reddy S, Sioutas C, Hsiai T, Jacobs JP, Araujo JA. Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models.. Environmental research, 2024.
25. Wiley KS, Gregg AM, Fox MM, Lagishetty V, Sandman CA, Jacobs JP, Glynn LM. Contact with caregivers is associated with composition of the infant gastrointestinal microbiome in the first 6 months of life.. American journal of biological anthropology, 2023.
26. Caremoli F, Huynh J, Lagishetty V, Markovic D, Braun J, Dong TS, Jacobs JP, Sternini C. Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity.. Nutrients, 2023.
27. Jacobs JP, Lee ML, Rechtman DJ, Sun AK, Autran C, Niklas V. Human milk oligosaccharides modulate the intestinal microbiome of healthy adults.. Scientific reports, 2023.
28. Lee JT, Simpson CA, Yang HH, Suh JD, Wang MB, Lagishetty V, Liang F, Jacobs JP. Fungal and Bacterial Microbiome in Sinus Mucosa of Patients with and without Chronic Rhinosinusitis.. The Laryngoscope, 2023.
29. Yang JC, Troutman R, Buri H, Gutta A, Situ J, Aja E, Jacobs JP. Ileal Dysbiosis Is Associated with Increased Acoustic Startle in the 22q11.2 Microdeletion Mouse Model of Schizophrenia.. Nutrients, 2023.
30. Zhao M, Jacobs JP. Fecal matters: Microbial signatures distinguish clinically relevant subtypes of precancerous colorectal polyps.. Cell host & microbe, 2023.
31. Cuff C, Lin LD, Mahurkar-Joshi S, Jacobs JP, Lagishetty V, Jaffe N, Smith J, Dong T, Sohn J, Chang L. Randomized controlled pilot study assessing fructose tolerance during fructose reintroduction in non-constipated irritable bowel syndrome patients successfully treated with a low FODMAP diet.. Neurogastroenterology and motility, 2023.
32. Chattopadhyay A, Mukherjee P, Sulaiman D, Wang H, Girjalva V, Dorreh N, Jacobs JP, Delk S, Moolenaar WH, Navab M, Reddy ST, Fogelman AM. Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.. Journal of lipid research, 2023.
33. Nguyen AD, Andréasson K, McMahan ZH, Bukiri H, Howlett N, Lagishetty V, Lee SM, Jacobs JP, Volkmann ER. Gastrointestinal tract involvement in systemic sclerosis: The roles of diet and the microbiome.. Seminars in arthritis and rheumatism, 2023.
34. Yang J, Lee R, Schulz Z, Hsu A, Pai J, Yang S, Henning SM, Huang J, Jacobs JP, Heber D, Li Z. Mixed Nuts as Healthy Snacks: Effect on Tryptophan Metabolism and Cardiovascular Risk Factors.. Nutrients, 2023.
35. Jacobs JP, Lagishetty V, Hauer MC, Labus JS, Dong TS, Toma R, Vuyisich M, Naliboff BD, Lackner JM, Gupta A, Tillisch K, Mayer EA. Multi-omics profiles of the intestinal microbiome in irritable bowel syndrome and its bowel habit subtypes.. Microbiome, 2023.
36. Luu K, Ye JY, Lagishetty V, Liang F, Hauer M, Sedighian F, Kwaan MR, Kazanjian KK, Hecht JR, Lin AY, Jacobs JP. Fecal and Tissue Microbiota Are Associated with Tumor T-Cell Infiltration and Mesenteric Lymph Node Involvement in Colorectal Cancer.. Nutrients, 2023.
37. Yang JC, Jacobs JP, Hwang M, Sabui S, Liang F, Said HM, Skupsky J. Biotin Deficiency Induces Intestinal Dysbiosis Associated with an Inflammatory Bowel Disease-like Phenotype.. Nutrients, 2023.
38. Dong TS, Katzka W, Yang JC, Chang C, Arias-Jayo N, Lagishetty V, Balioukova A, Chen Y, Dutson E, Li Z, Mayer EA, Pisegna JR, Sanmiguel C, Jacobs JP. Microbial changes from bariatric surgery alters glucose-dependent insulinotropic polypeptide and prevents fatty liver disease.. Gut microbes, 2023.
39. Maggiotto LV, Ghosh S, Shin BC, Ganguly A, Lagishetty V, Jacobs JP, Devaskar SU. Variation in the Early Life and Adult Intestinal Microbiome of Intra-Uterine Growth Restricted Rat Offspring Exposed to a High Fat and Fructose Diet.. Nutrients, 2023.
40. Chernikova DA, Zhao MY, Jacobs JP. Microbiome Therapeutics for Food Allergy.. Nutrients, 2022.
41. Kim HN, Kim MJ, Jacobs JP, Yang HJ. Altered Gastric Microbiota and Inflammatory Cytokine Responses in Patients with Helicobacter pylori-Negative Gastric Cancer.. Nutrients, 2022.
42. Kim CE, Yoon LS, Michels KB, Tranfield W, Jacobs JP, May FP. The Impact of Prebiotic, Probiotic, and Synbiotic Supplements and Yogurt Consumption on the Risk of Colorectal Neoplasia among Adults: A Systematic Review.. Nutrients, 2022.
43. Gong J, Thomassian S, Kim S, Gresham G, Moshayedi N, Ye JY, Yang JC, Jacobs JP, Lo S, Nissen N, Gaddam S, Tighiouart M, Osipov A, Hendifar A. Author Correction: Phase I trial of Bermekimab with nanoliposomal irinotecan and 5‑fuorouracil/folinic acid in advanced pancreatic ductal adenocarcinoma.. Scientific reports, 2022.
44. Gong J, Thomassian S, Kim S, Gresham G, Moshayedi N, Ye JY, Yang JC, Jacobs JP, Lo S, Nissen N, Gaddam S, Tighiouart M, Osipov A, Hendifar A. Phase I trial of Bermekimab with nanoliposomal irinotecan and 5-fluorouracil/folinic acid in advanced pancreatic ductal adenocarcinoma.. Scientific reports, 2022.
45. Jacobs JP, Goudarzi M, Lagishetty V, Li D, Mak T, Tong M, Ruegger P, Haritunians T, Landers C, Fleshner P, Vasiliauskas E, Ippoliti A, Melmed G, Shih D, Targan S, Borneman J, Fornace AJ, McGovern DPB, Braun J. Crohn's disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome.. Genome medicine, 2022.
46. Sauk JS, Ryu HJ, Labus JS, Khandadash A, Ahdoot AI, Lagishetty V, Katzka W, Wang H, Naliboff B, Jacobs JP, Mayer EA. High Perceived Stress is Associated With Increased Risk of Ulcerative Colitis Clinical Flares.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022.
47. Medel-Matus JS, Simpson CA, Ahdoot AI, Shin D, Sankar R, Jacobs JP, Mazarati AM. Modification of post-traumatic epilepsy by fecal microbiota transfer.. Epilepsy & behavior : E&B, 2022.
48. Choo C, Mahurkar-Joshi S, Dong TS, Lenhart A, Lagishetty V, Jacobs JP, Labus JS, Jaffe N, Mayer EA, Chang L. Colonic mucosal microbiota is associated with bowel habit subtype and abdominal pain in patients with irritable bowel syndrome.. American journal of physiology. Gastrointestinal and liver physiology, 2022.
49. Bae SS, Dong TS, Wang J, Lagishetty V, Katzka W, Jacobs JP, Charles-Schoeman C. Altered Gut Microbiome in Patients With Dermatomyositis.. ACR open rheumatology, 2022.
50. Medel-Matus JS, Lagishetty V, Santana-Gomez C, Shin D, Mowrey W, Staba RJ, Galanopoulou AS, Sankar R, Jacobs JP, Mazarati AM. Susceptibility to epilepsy after traumatic brain injury is associated with preexistent gut microbiome profile.. Epilepsia, 2022.
51. Lee SM, Milillo MM, Krause-Sorio B, Siddarth P, Kilpatrick L, Narr KL, Jacobs JP, Lavretsky H. Gut Microbiome Diversity and Abundance Correlate with Gray Matter Volume (GMV) in Older Adults with Depression.. International journal of environmental research and public health, 2022.
52. Andréasson K, Lee SM, Lagishetty V, Wu M, Howlett N, English J, Hesselstrand R, Clements PJ, Jacobs JP, Volkmann ER. Disease Features and Gastrointestinal Microbial Composition in Patients with Systemic Sclerosis from Two Independent Cohorts.. ACR open rheumatology, 2022.
53. Yang J, Lagishetty V, Kurnia P, Henning SM, Ahdoot AI, Jacobs JP. Microbial and Chemical Profiles of Commercial Kombucha Products.. Nutrients, 2022.
54. Yang J, Germano PM, Oh S, Wang S, Wang J, Lee R, Paige H, Yang S, Henning SM, Zhong J, Jacobs JP, Li Z. Pomegranate Extract Improves Colitis in IL-10 Knockout Mice Fed a High Fat High Sucrose Diet.. Molecular nutrition & food research, 2022.
55. Dong TS, Guan M, Mayer EA, Stains J, Liu C, Vora P, Jacobs JP, Lagishetty V, Chang L, Barry RL, Gupta A. Obesity is associated with a distinct brain-gut microbiome signature that connects Prevotella and Bacteroides to the brain's reward center.. Gut microbes, 2022.
56. Zhang K, Paul KC, Jacobs JP, Chou HL, Duarte Folle A, Del Rosario I, Yu Y, Bronstein JM, Keener AM, Ritz B. Parkinson's Disease and the Gut Microbiome in Rural California.. Journal of Parkinson's disease, 2022.
57. Yoon LS, Jacobs JP, Hoehner J, Pereira A, Gana JC, Corvalán C, Michels KB. The Association Between Breast Density and Gut Microbiota Composition at 2 Years Post-Menarche: A Cross-Sectional Study of Adolescents in Santiago, Chile.. Frontiers in cellular and infection microbiology, 2021.
58. Zhou Y, Duan L, Zeng Y, Niu L, Pu Y, Jacobs JP, Chang C, Wang J, Khalique A, Pan K, Fang J, Jing B, Zeng D, Ni X. The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.. Frontiers in immunology, 2021.
59. Jacobs JP, Gupta A, Bhatt RR, Brawer J, Gao K, Tillisch K, Lagishetty V, Firth R, Gudleski GD, Ellingson BM, Labus JS, Naliboff BD, Lackner JM, Mayer EA. Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement.. Microbiome, 2021.
60. Dong TS, Jacobs JP, Agopian V, Pisegna JR, Ayoub W, Durazo F, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Lagishetty V, Fiehn O, Goodman MT, Elashoff D, Hussain SK. Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis.. Digestive diseases and sciences, 2021.
61. Mukherjee P, Chattopadhyay A, Grijalva V, Dorreh N, Lagishetty V, Jacobs JP, Clifford BL, Vallim T, Mack JJ, Navab M, Reddy ST, Fogelman AM. Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation.. Journal of lipid research, 2021.
62. Shieh A, Lee SM, Lagishetty V, Gottleib C, Jacobs JP, Adams JS. Pilot Trial of Vitamin D3 and Calcifediol in Healthy Vitamin D Deficient Adults: Does It Change the Fecal Microbiome?. The Journal of clinical endocrinology and metabolism, 2021.
63. Mirzayi C, Renson A, Genomic Standards Consortium, Massive Analysis and Quality Control Society, Zohra F, Elsafoury S, Geistlinger L, Kasselman LJ, Eckenrode K, van de Wijgert J, Loughman A, Marques FZ, MacIntyre DA, Arumugam M, Azhar R, Beghini F, Bergstrom K, Bhatt A, Bisanz JE, Braun J, Bravo HC, Buck GA, Bushman F, Casero D, Clarke G, Collado MC, Cotter PD, Cryan JF, Demmer RT, Devkota S, Elinav E, Escobar JS, Fettweis J, Finn RD, Fodor AA, Forslund S, Franke A, Furlanello C, Gilbert J, Grice E, Haibe-Kains B, Handley S, Herd P, Holmes S, Jacobs JP, Karstens L, Knight R, Knights D, Koren O, Kwon DS, Langille M, Lindsay B, McGovern D, McHardy AC, McWeeney S, Mueller NT, Nezi L, Olm M, Palm N, Pasolli E, Raes J, Redinbo MR, Rühlemann M, Balfour Sartor R, Schloss PD, Schriml L, Segal E, Shardell M, Sharpton T, Smirnova E, Sokol H, Sonnenburg JL, Srinivasan S, Thingholm LB, Turnbaugh PJ, Upadhyay V, Walls RL, Wilmes P, Yamada T, Zeller G, Zhang M, Zhao N, Zhao L, Bao W, Culhane A, Devanarayan V, Dopazo J, Fan X, Fischer M, Jones W, Kusko R, Mason CE, Mercer TR, Sansone SA, Scherer A, Shi L, Thakkar S, Tong W, Wolfinger R, Hunter C, Segata N, Huttenhower C, Dowd JB, Jones HE, Waldron L. Reporting guidelines for human microbiome research: the STORMS checklist.. Nature medicine, 2021.
64. Chang CC, Huang ZY, Shih SF, Luo Y, Ko A, Cui Q, Sumner J, Cavallero S, Das S, Gao W, Sinsheimer J, Bui A, Jacobs JP, Pajukanta P, Wu H, Tai YC, Li Z, Hsiai TK. Electrical impedance tomography for non-invasive identification of fatty liver infiltrate in overweight individuals.. Scientific reports, 2021.
65. Katzka W, Dong TS, Luu K, Lagishetty V, Sedighian F, Arias-Jayo N, Jacobs JP, Hsu HY. The Ocular Microbiome Is Altered by Sampling Modality and Age.. Translational vision science & technology, 2021.
66. Jones JD, Dominguez B, Bunch J, Uribe C, Valenzuela Y, Jacobs JP. A bidirectional relationship between anxiety, depression and gastrointestinal symptoms in Parkinson's disease.. Clinical parkinsonism & related disorders, 2021.
67. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot AI, Ye J, Li Z, Pisegna JR, Jacobs JP. The Intestinal Microbiome Predicts Weight Loss on a Calorie-Restricted Diet and Is Associated With Improved Hepatic Steatosis.. Frontiers in nutrition, 2021.
68. Fox M, Lee SM, Wiley KS, Lagishetty V, Sandman CA, Jacobs JP, Glynn LM. Development of the infant gut microbiome predicts temperament across the first year of life.. Development and psychopathology, 2021.
69. Martinez JE, Kahana DD, Ghuman S, Wilson HP, Wilson J, Kim SCJ, Lagishetty V, Jacobs JP, Sinha-Hikim AP, Friedman TC. Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome.. Frontiers in endocrinology, 2021.
70. Coley EJL, Mayer EA, Osadchiy V, Chen Z, Subramanyam V, Zhang Y, Hsiao EY, Gao K, Bhatt R, Dong T, Vora P, Naliboff B, Jacobs JP, Gupta A. Early life adversity predicts brain-gut alterations associated with increased stress and mood.. Neurobiology of stress, 2021.
71. Lenhart A, Dong T, Joshi S, Jaffe N, Choo C, Liu C, Jacobs JP, Lagishetty V, Shih W, Labus JS, Gupta A, Tillisch K, Mayer EA, Chang L. Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021.
72. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot AI, Ye J, Li Z, Pisegna JR, Jacobs JP. Gut microbiome profiles associated with steatosis severity in metabolic associated fatty liver disease.. Hepatoma research, 2021.
73. Mazarati A, Medel-Matus JS, Shin D, Jacobs JP, Sankar R. Disruption of intestinal barrier and endotoxemia after traumatic brain injury: Implications for post-traumatic epilepsy.. Epilepsia, 2021.
74. Lee SM, Dong TS, Krause-Sorio B, Siddarth P, Milillo MM, Lagishetty V, Datta T, Aguilar-Faustino Y, Jacobs JP, Lavretsky H. The intestinal microbiota as a predictor for antidepressant treatment outcome in geriatric depression: a prospective pilot study.. International psychogeriatrics, 2021.
75. Turkiewicz J, Bhatt RR, Wang H, Vora P, Krause B, Sauk JS, Jacobs JP, Bernstein CN, Kornelsen J, Labus JS, Gupta A, Mayer EA. Altered brain structural connectivity in patients with longstanding gut inflammation is correlated with psychological symptoms and disease duration.. NeuroImage. Clinical, 2021.
76. Dreskin BW, Luu K, Dong TS, Benhammou J, Lagishetty V, Vu J, Sanford D, Durazo F, Agopian VG, Jacobs JP, Pisegna JR, Hussain SK. Specimen Collection and Analysis of the Duodenal Microbiome.. Journal of visualized experiments : JoVE, 2021.
77. Volkmann ER, Hoffmann-Vold AM, Chang YL, Lagishetty V, Clements PJ, Midtvedt Ø, Molberg Ø, Braun J, Jacobs JP. Longitudinal Characterisation of the Gastrointestinal Tract Microbiome in Systemic Sclerosis.. European Medical Journal (Chelmsford, England), 2020.
78. Hung TKW, Dong TS, Chen Z, Elashoff D, Sinsheimer JS, Jacobs JP, Lagishetty V, Vora P, Stains J, Mayer EA, Gupta A. Understanding the Heterogeneity of Obesity and the Relationship to the Brain-Gut Axis.. Nutrients, 2020.
79. Jasinska AJ, Dong TS, Lagishetty V, Katzka W, Jacobs JP, Schmitt CA, Cramer JD, Ma D, Coetzer WG, Grobler JP, Turner TR, Freimer N, Pandrea I, Apetrei C. Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys.. Microbiome, 2020.
80. Osadchiy V, Mayer EA, Gao K, Labus JS, Naliboff B, Tillisch K, Chang L, Jacobs JP, Hsiao EY, Gupta A. Analysis of brain networks and fecal metabolites reveals brain-gut alterations in premenopausal females with irritable bowel syndrome.. Translational psychiatry, 2020.
81. Bergstrom K, Shan X, Casero D, Batushansky A, Lagishetty V, Jacobs JP, Hoover C, Kondo Y, Shao B, Gao L, Zandberg W, Noyovitz B, McDaniel JM, Gibson DL, Pakpour S, Kazemian N, McGee S, Houchen CW, Rao CV, Griffin TM, Sonnenburg JL, McEver RP, Braun J, Xia L. Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota.. Science (New York, N.Y.), 2020.
82. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot A, Li Z, Pisegna JR, Jacobs JP. A High Protein Calorie Restriction Diet Alters the Gut Microbiome in Obesity.. Nutrients, 2020.
83. Dong TS, Gupta A, Jacobs JP, Lagishetty V, Gallagher E, Bhatt RR, Vora P, Osadchiy V, Stains J, Balioukova A, Chen Y, Dutson E, Mayer EA, Sanmiguel C. Improvement in Uncontrolled Eating Behavior after Laparoscopic Sleeve Gastrectomy Is Associated with Alterations in the Brain-Gut-Microbiome Axis in Obese Women.. Nutrients, 2020.
84. Dong TS, Mayer EA, Osadchiy V, Chang C, Katzka W, Lagishetty V, Gonzalez K, Kalani A, Stains J, Jacobs JP, Longo VD, Gupta A. A Distinct Brain-Gut-Microbiome Profile Exists for Females with Obesity and Food Addiction.. Obesity (Silver Spring, Md.), 2020.
85. Hussain SK, Dong TS, Agopian V, Pisegna JR, Durazo FA, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Ayoub WS, Lagishetty V, Elashoff D, Goodman MT, Jacobs JP. Dietary Protein, Fiber and Coffee Are Associated with Small Intestine Microbiome Composition and Diversity in Patients with Liver Cirrhosis.. Nutrients, 2020.
86. Dong TS, Katzka W, Lagishetty V, Luu K, Hauer M, Pisegna J, Jacobs JP. A Microbial Signature Identifies Advanced Fibrosis in Patients with Chronic Liver Disease Mainly Due to NAFLD.. Scientific reports, 2020.
87. Jones JD, Rahmani E, Garcia E, Jacobs JP. Gastrointestinal symptoms are predictive of trajectories of cognitive functioning in de novo Parkinson's disease.. Parkinsonism & related disorders, 2020.
88. Dong TS, Chang HH, Hauer M, Lagishetty V, Katzka W, Rozengurt E, Jacobs JP, Eibl G. Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity.. American journal of physiology. Gastrointestinal and liver physiology, 2019.
89. Dong TS, Jacobs JP, Hussain SK. Microbial Profiles of Cirrhosis in the Human Small Intestine.. Current gastroenterology reports, 2019.
90. Hakimian JK, Dong TS, Barahona JA, Lagishetty V, Tiwari S, Azani D, Barrera M, Lee S, Severino AL, Mittal N, Cahill CM, Jacobs JP, Walwyn WM. Dietary Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Opioid-Seeking Behaviors and Alters the Gut Microbiome.. Nutrients, 2019.
91. Jacobs JP, Mayer EA. Psychobiotics: Shaping the Mind With Gut Bacteria.. The American journal of gastroenterology, 2019.
92. Dong TS, Jacobs JP. Nonalcoholic fatty liver disease and the gut microbiome: Are bacteria responsible for fatty liver?. Experimental biology and medicine (Maywood, N.J.), 2019.
93. Britton GJ, Contijoch EJ, Mogno I, Vennaro OH, Llewellyn SR, Ng R, Li Z, Mortha A, Merad M, Das A, Gevers D, McGovern DPB, Singh N, Braun J, Jacobs JP, Clemente JC, Grinspan A, Sands BE, Colombel JF, Dubinsky MC, Faith JJ. Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice.. Immunity, 2019.
94. Jacobs JP, Dong TS, Agopian V, Lagishetty V, Sundaram V, Noureddin M, Ayoub WS, Durazo F, Benhammou J, Enayati P, Elashoff D, Goodman MT, Pisegna J, Hussain S. Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study.. Hepatology research : the official journal of the Japan Society of Hepatology, 2018.
95. Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQ. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome.. Mucosal immunology, 2018.
96. Wang J, Ghali S, Xu C, Mussatto CC, Ortiz C, Lee EC, Tran DH, Jacobs JP, Lagishetty V, Faull KF, Moller T, Rossetti M, Chen X, Koon HW. Ceragenin CSA13 Reduces Clostridium difficile Infection in Mice by Modulating the Intestinal Microbiome and Metabolites.. Gastroenterology, 2018.
97. Xu C, Ghali S, Wang J, Shih DQ, Ortiz C, Mussatto CC, Lee EC, Tran DH, Jacobs JP, Lagishetty V, Fleshner P, Robbins L, Vu M, Hing TC, McGovern DPB, Koon HW. CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway.. Scientific reports, 2017.
98. Wang L, Jacobs JP, Lagishetty V, Yuan PQ, Wu SV, Million M, Reeve JR, Pisegna JR, Taché Y. High-protein diet improves sensitivity to cholecystokinin and shifts the cecal microbiome without altering brain inflammation in diet-induced obesity in rats.. American journal of physiology. Regulatory, integrative and comparative physiology, 2017.
99. Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J. Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts.. BMJ open gastroenterology, 2017.
100. Moussaoui N, Jacobs JP, Larauche M, Biraud M, Million M, Mayer E, Taché Y. Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex.. Journal of neurogastroenterology and motility, 2017.
101. Jacobs JP, Lin L, Goudarzi M, Ruegger P, McGovern DP, Fornace AJ, Borneman J, Xia L, Braun J. Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.. Gut microbes, 2016.
102. Goudarzi M, Mak TD, Jacobs JP, Moon BH, Strawn SJ, Braun J, Brenner DJ, Fornace AJ, Li HH. An Integrated Multi-Omic Approach to Assess Radiation Injury on the Host-Microbiome Axis.. Radiation research, 2016.
103. Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor DD, Regueiro M, Simms LA, Stempak JM, Targan SR, Törkvist L, Sharma Y, Devlin B, Borneman J, Hakonarson H, Xavier RJ, Daly M, Brant SR, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern DP, Duerr RH. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition.. Gastroenterology, 2016.
104. Jacobs JP, Goudarzi M, Singh N, Tong M, McHardy IH, Ruegger P, Asadourian M, Moon BH, Ayson A, Borneman J, McGovern DP, Fornace AJ, Braun J, Dubinsky M. A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients.. Cellular and molecular gastroenterology and hepatology, 2016.
105. Volkmann ER, Chang YL, Barroso N, Furst DE, Clements PJ, Gorn AH, Roth BE, Conklin JL, Getzug T, Borneman J, McGovern DP, Tong M, Jacobs JP, Braun J. Association of Systemic Sclerosis With a Unique Colonic Microbial Consortium.. Arthritis & rheumatology (Hoboken, N.J.), 2016.
106. Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis.. Current protocols in immunology, 2014.
107. Jacobs JP, Braun J. Immune and genetic gardening of the intestinal microbiome.. FEBS letters, 2014.
108. Jacobs JP, Ortiz-Lopez A, Campbell JJ, Gerard CJ, Mathis D, Benoist C. Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model.. Arthritis and rheumatism, 2010.
109. Jacobs JP, Wu HJ, Benoist C, Mathis D. IL-17-producing T cells can augment autoantibody-induced arthritis.. Proceedings of the National Academy of Sciences of the United States of America, 2009.
110. Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D. Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model.. Arthritis and rheumatism, 2007.
111. Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C. Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis.. Arthritis and rheumatism, 2004.
112. Solomon DH, Katz JN, Jacobs JP, La Tourette AM, Coblyn J. Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: rates and predictors of care in an academic rheumatology practice.. Arthritis and rheumatism, 2002.