Joseph Pisegna*

Joseph R Pisegna

Professor-in-Residence, Medicine, University of California Los Angeles

Professor-in-Residence, Human Genetics, University of California Los Angeles


  1. Aguilar D, Zhu F, Millet A, Millet N, Germano P, Pisegna J, Doherty TA, Swidergall M, Jendzjowsky N. Sensory neurons regulate stimulus-dependent humoral immunity.. bioRxiv : the preprint server for biology, 2024.
  2. Pisegna JR. Diagnosis and Treatment Design Strategy for Gastric Neoplasia.. The American journal of gastroenterology, 2023.
  3. Jeon CY, Adeniran E, Stewart C, Papachristou GI, Pisegna JR, Kuc AA, Buxbaum JL, Pandol SJ, Yadav D. Female patients delay seeking medical care with alcohol-associated acute pancreatitis.. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2023.
  4. Vu JP, Luong L, Sanford D, Oh S, Kuc A, Pisegna R, Lewis M, Pisegna JR, Germano PM. PACAP and VIP Neuropeptides' and Receptors' Effects on Appetite, Satiety and Metabolism.. Biology, 2023.
  5. Robertson DJ, Dominitz JA, Beed A, Boardman KD, Del Curto BJ, Guarino PD, Imperiale TF, LaCasse A, Larson MF, Gupta S, Lieberman D, Planeta B, Shaukat A, Sultan S, Menees SB, Saini SD, Schoenfeld P, Goebel S, von Rosenvinge EC, Baffy G, Halasz I, Pedrosa MC, Kahng LS, Cassim R, Greer KB, Kinnard MF, Bhatt DB, Dunbar KB, Harford WV, Mengshol JA, Olson JE, Patel SG, Antaki F, Fisher DA, Sullivan BA, Lenza C, Prajapati DN, Wong H, Beyth R, Lieb JG, Manlolo J, Ona FV, Cole RA, Khalaf N, Kahi CJ, Kohli DR, Rai T, Sharma P, Anastasiou J, Hagedorn C, Fernando RS, Jackson CS, Jamal MM, Lee RH, Merchant F, May FP, Pisegna JR, Omer E, Parajuli D, Said A, Nguyen TD, Tombazzi CR, Feldman PA, Jacob L, Koppelman RN, Lehenbauer KP, Desai DS, Madhoun MF, Tierney WM, Ho MQ, Hockman HJ, Lopez C, Carter Paulson E, Tobi M, Pinillos HL, Young M, Ho NC, Mascarenhas R, Promrat K, Mutha PR, Pandak WM, Shah T, Schubert M, Pancotto FS, Gawron AJ, Underwood AE, Ho SB, Magno-Pagatzaurtundua P, Toro DH, Beymer CH, Kaz AM, Elwing J, Gill JA, Goldsmith SF, Yao MD, Protiva P, Pohl H, Kyriakides T, CONFIRM Study Group. Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.. JAMA network open, 2023.
  6. Benhammou JN, Qiao B, Ko A, Sinnett-Smith J, Pisegna JR, Rozengurt E. Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton.. American journal of physiology. Gastrointestinal and liver physiology, 2023.
  7. Darci-Maher N, Alvarez M, Arasu UT, Selvarajan I, Lee SHT, Pan DZ, Miao Z, Das SS, Kaminska D, Örd T, Benhammou JN, Wabitsch M, Pisegna JR, Männistö V, Pietiläinen KH, Laakso M, Sinsheimer JS, Kaikkonen MU, Pihlajamäki J, Pajukanta P. Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease.. EBioMedicine, 2023.
  8. Chen W, Zhou B, Jeon CY, Xie F, Lin YC, Butler RK, Zhou Y, Luong TQ, Lustigova E, Pisegna JR, Wu BU. Machine learning versus regression for prediction of sporadic pancreatic cancer.. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2023.
  9. Turner MA, Cox KE, Liu S, Neel N, Amirfakhri S, Nishino H, Hosseini M, Alcantara JA, Abd El-Hafeez AA, Lwin TM, Mallya K, Pisegna JR, Singh SK, Ghosh P, Hoffman RM, Batra SK, Bouvet M. Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer.. Current issues in molecular biology, 2023.
  10. Alvarez M, Benhammou JN, Rao S, Mishra L, Pisegna JR, Pajukanta P. Isolation of Nuclei from Human Snap-frozen Liver Tissue for Single-nucleus RNA Sequencing.. Bio-protocol, 2023.
  11. Dong TS, Katzka W, Yang JC, Chang C, Arias-Jayo N, Lagishetty V, Balioukova A, Chen Y, Dutson E, Li Z, Mayer EA, Pisegna JR, Sanmiguel C, Jacobs JP. Microbial changes from bariatric surgery alters glucose-dependent insulinotropic polypeptide and prevents fatty liver disease.. Gut microbes, 2023.
  12. Chen W, Zhou Y, Xie F, Butler RK, Jeon CY, Luong TQ, Zhou B, Lin YC, Lustigova E, Pisegna JR, Kim S, Wu BU. Derivation and External Validation of Machine Learning-Based Model for Detection of Pancreatic Cancer.. The American journal of gastroenterology, 2022.
  13. Yu R, Rao J, Zhai J, Hecht JR, Pisegna JR. Familial Duodenal Somatostatinomatosis Not Associated With a Known Genetic Syndrome.. Pancreas, 2022.
  14. Alvarez M, Benhammou JN, Darci-Maher N, French SW, Han SB, Sinsheimer JS, Agopian VG, Pisegna JR, Pajukanta P. Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival.. Genome medicine, 2022.
  15. Sanford D, Luong L, Vu JP, Oh S, Gabalski A, Lewis M, Pisegna JR, Germano P. The VIP/VPAC1R Pathway Regulates Energy and Glucose Homeostasis by Modulating GLP-1, Glucagon, Leptin and PYY Levels in Mice.. Biology, 2022.
  16. Rao S, Yang X, Ohshiro K, Zaidi S, Wang Z, Shetty K, Xiang X, Hassan MI, Mohammad T, Latham PS, Nguyen BN, Wong L, Yu H, Al-Abed Y, Mishra B, Vacca M, Guenigault G, Allison MED, Vidal-Puig A, Benhammou JN, Alvarez M, Pajukanta P, Pisegna JR, Mishra L. β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development.. Science translational medicine, 2021.
  17. Dong TS, Jacobs JP, Agopian V, Pisegna JR, Ayoub W, Durazo F, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Lagishetty V, Fiehn O, Goodman MT, Elashoff D, Hussain SK. Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis.. Digestive diseases and sciences, 2021.
  18. Jeon CY, Kim S, Lin YC, Risch HA, Goodarzi MO, Nuckols TK, Freedland SJ, Pandol SJ, Pisegna JR. Prediction of Pancreatic Cancer in Diabetes Patients with Worsening Glycemic Control.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021.
  19. Hashemi L, Zhang Q, Getahun D, Jasuja GK, McCracken C, Pisegna J, Roblin D, Silverberg MJ, Tangpricha V, Vupputuri S, Goodman M. Longitudinal Changes in Liver Enzyme Levels Among Transgender People Receiving Gender Affirming Hormone Therapy.. The journal of sexual medicine, 2021.
  20. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot AI, Ye J, Li Z, Pisegna JR, Jacobs JP. The Intestinal Microbiome Predicts Weight Loss on a Calorie-Restricted Diet and Is Associated With Improved Hepatic Steatosis.. Frontiers in nutrition, 2021.
  21. Jeon CY, Papachristou GI, Pisegna JR, Pendergast FJ, Lin YC, Cherpitel CJ, Ye Y, Pandol SJ, Yadav D. A Case-CrossovEr study deSign to inform tailored interventions to prevent disease progression in Acute Pancreatitis (ACCESS-AP) - study design and population.. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2021.
  22. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot AI, Ye J, Li Z, Pisegna JR, Jacobs JP. Gut microbiome profiles associated with steatosis severity in metabolic associated fatty liver disease.. Hepatoma research, 2021.
  23. Dreskin BW, Luu K, Dong TS, Benhammou J, Lagishetty V, Vu J, Sanford D, Durazo F, Agopian VG, Jacobs JP, Pisegna JR, Hussain SK. Specimen Collection and Analysis of the Duodenal Microbiome.. Journal of visualized experiments : JoVE, 2021.
  24. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot A, Li Z, Pisegna JR, Jacobs JP. A High Protein Calorie Restriction Diet Alters the Gut Microbiome in Obesity.. Nutrients, 2020.
  25. Auerbach MS, Pisegna JR, Kim S, Yu R. Three Cases of Diffuse, Intense Stomach Uptake on DOTATATE PET.. Clinical nuclear medicine, 2020.
  26. Marcus EA, Pisegna JR. Editorial: tegoprazan-the newest advance in the management of acid-related diseases.. Alimentary pharmacology & therapeutics, 2020.
  27. Benhammou JN, Moon AM, Pisegna JR, Su F, Vutien P, Moylan CA, Ioannou GN. Nonalcoholic Fatty Liver Disease Risk Factors Affect Liver-Related Outcomes After Direct-Acting Antiviral Treatment for Hepatitis C.. Digestive diseases and sciences, 2020.
  28. Alvarez M, Rahmani E, Jew B, Garske KM, Miao Z, Benhammou JN, Ye CJ, Pisegna JR, Pietiläinen KH, Halperin E, Pajukanta P. Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM.. Scientific reports, 2020.
  29. Hussain SK, Dong TS, Agopian V, Pisegna JR, Durazo FA, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Ayoub WS, Lagishetty V, Elashoff D, Goodman MT, Jacobs JP. Dietary Protein, Fiber and Coffee Are Associated with Small Intestine Microbiome Composition and Diversity in Patients with Liver Cirrhosis.. Nutrients, 2020.
  30. Aby ES, Winters AC, Lin J, Bui A, Kawamoto J, Goetz MB, Bhattacharya D, Pisegna JR, May FP, Patel AA, Benhammou JN. A Telephone and Mail Outreach Program Successfully Increases Uptake of Hepatocellular Carcinoma Surveillance.. Hepatology communications, 2020.
  31. Dong TS, Katzka W, Lagishetty V, Luu K, Hauer M, Pisegna J, Jacobs JP. A Microbial Signature Identifies Advanced Fibrosis in Patients with Chronic Liver Disease Mainly Due to NAFLD.. Scientific reports, 2020.
  32. Dong TS, Vu JP, Oh S, Sanford D, Pisegna JR, Germano P. Intraperitoneal Treatment of Kisspeptin Suppresses Appetite and Energy Expenditure and Alters Gastrointestinal Hormones in Mice.. Digestive diseases and sciences, 2019.
  33. King CH, Desai H, Sylvetsky AC, LoTempio J, Ayanyan S, Carrie J, Crandall KA, Fochtman BC, Gasparyan L, Gulzar N, Howell P, Issa N, Krampis K, Mishra L, Morizono H, Pisegna JR, Rao S, Ren Y, Simonyan V, Smith K, VedBrat S, Yao MD, Mazumder R. Baseline human gut microbiota profile in healthy people and standard reporting template.. PloS one, 2019.
  34. Benhammou JN, Ko A, Alvarez M, Kaikkonen MU, Rankin C, Garske KM, Padua D, Bhagat Y, Kaminska D, Kärjä V, Pihlajamäki J, Pisegna JR, Pajukanta P. Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA.. Hepatology communications, 2019.
  35. Tirkes T, Yadav D, Conwell DL, Territo PR, Zhao X, Venkatesh SK, Kolipaka A, Li L, Pisegna JR, Pandol SJ, Park WG, Topazian M, Serrano J, Fogel EL, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Magnetic resonance imaging as a non-invasive method for the assessment of pancreatic fibrosis (MINIMAP): a comprehensive study design from the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer.. Abdominal radiology (New York), 2019.
  36. Van C, Condro MC, Lov K, Zhu R, Ricaflanca PT, Ko HH, Diep AL, Hoang AQ, Pisegna J, Rohrer H, Waschek JA. Correction to: PACAP/PAC1 Regulation of Inflammation via Catecholaminergic Neurons in a Model of Multiple Sclerosis.. Journal of molecular neuroscience : MN, 2019.
  37. Baecker A, Kim S, Risch HA, Nuckols TK, Wu BU, Hendifar AE, Pandol SJ, Pisegna JR, Jeon CY. Do changes in health reveal the possibility of undiagnosed pancreatic cancer? Development of a risk-prediction model based on healthcare claims data.. PloS one, 2019.
  38. Garske KM, Pan DZ, Miao Z, Bhagat YV, Comenho C, Robles CR, Benhammou JN, Alvarez M, Ko A, Ye CJ, Pisegna JR, Mohlke KL, Sinsheimer JS, Laakso M, Pajukanta P. Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.. Nature metabolism, 2019.
  39. Jacob N, Dasharathy SS, Bui V, Benhammou JN, Grody WW, Singh RR, Pisegna JR. Generalized Cytokine Increase in the Setting of a Multisystem Clinical Disorder and Carcinoid Syndrome Associated with a Novel NLRP12 Variant.. Digestive diseases and sciences, 2019.
  40. Sanford D, Luong L, Gabalski A, Oh S, Vu JP, Pisegna JR, Germano P. An Intraperitoneal Treatment with Calcitonin Gene-Related Peptide (CGRP) Regulates Appetite, Energy Intake/Expenditure, and Metabolism.. Journal of molecular neuroscience : MN, 2018.
  41. Dong T, Pisegna J. Passing the "Acid Test": Do Proton Pump Inhibitors Affect the Composition of the Microbiome?. Digestive diseases and sciences, 2018.
  42. Sho S, Court CM, Winograd P, Toste PA, Pisegna JR, Lewis M, Donahue TR, Hines OJ, Reber HA, Dawson DW, Tomlinson JS. A Prognostic Scoring System for the Prediction of Metastatic Recurrence Following Curative Resection of Pancreatic Neuroendocrine Tumors.. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018.
  43. Dong TS, Aby ES, Benhammou JN, Kawamoto J, Han SH, May FP, Pisegna JR. Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c.. World journal of hepatology, 2018.
  44. Jacobs JP, Dong TS, Agopian V, Lagishetty V, Sundaram V, Noureddin M, Ayoub WS, Durazo F, Benhammou J, Enayati P, Elashoff D, Goodman MT, Pisegna J, Hussain S. Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study.. Hepatology research : the official journal of the Japan Society of Hepatology, 2018.
  45. Van C, Condro MC, Lov K, Zhu R, Ricaflanca PT, Ko HH, Diep AL, Hoang AQ, Pisegna J, Rohrer H, Waschek JA. PACAP/PAC1 Regulation of Inflammation via Catecholaminergic Neurons in a Model of Multiple Sclerosis.. Journal of molecular neuroscience : MN, 2018.
  46. Lee UK, Chang TI, Polanco JC, Pisegna JR, Friedlander AH. Prevalence of Panoramically Imaged Carotid Atheromas in Alcoholic Patients With Chronic Pancreatitis and Comorbid Diabetes.. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2018.
  47. Mohapatra SS, Batra SK, Bharadwaj S, Bouvet M, Cosman B, Goel A, Jogunoori W, Kelley MJ, Mishra L, Mishra B, Mohapatra S, Patel B, Pisegna JR, Raufman JP, Rao S, Roy H, Scheuner M, Singh S, Vidyarthi G, White J. Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions.. Digestive diseases and sciences, 2018.
  48. Benhammou JN, Dong TS, May FP, Kawamoto J, Dixit R, Jackson S, Dixit V, Bhattacharya D, Han SB, Pisegna JR. Race affects SVR12 in a large and ethnically diverse hepatitis C-infected patient population following treatment with direct-acting antivirals: Analysis of a single-center Department of Veterans Affairs cohort.. Pharmacology research & perspectives, 2018.
  49. Ehrlich D, Jamaluddin N, Pisegna J, Padua D. A Challenging Case of Severe Ulcerative Colitis following the Initiation of Secukinumab for Ankylosing Spondylitis.. Case reports in gastrointestinal medicine, 2018.
  50. Aby ES, Dong TS, Kawamoto J, Pisegna JR, Benhammou JN. Impact of sustained virologic response on chronic kidney disease progression in hepatitis C.. World journal of hepatology, 2017.
  51. Vu JP, Luong L, Parsons WF, Oh S, Sanford D, Gabalski A, Lighton JR, Pisegna JR, Germano PM. Long-Term Intake of a High-Protein Diet Affects Body Phenotype, Metabolism, and Plasma Hormones in Mice.. The Journal of nutrition, 2017.
  52. Jackson SB, Villano NP, Benhammou JN, Lewis M, Pisegna JR, Padua D. Gastrointestinal Manifestations of Hereditary Hemorrhagic Telangiectasia (HHT): A Systematic Review of the Literature.. Digestive diseases and sciences, 2017.
  53. Minalyan A, Gabrielyan L, Scott D, Jacobs J, Pisegna JR. The Gastric and Intestinal Microbiome: Role of Proton Pump Inhibitors.. Current gastroenterology reports, 2017.
  54. Wang L, Jacobs JP, Lagishetty V, Yuan PQ, Wu SV, Million M, Reeve JR, Pisegna JR, Taché Y. High-protein diet improves sensitivity to cholecystokinin and shifts the cecal microbiome without altering brain inflammation in diet-induced obesity in rats.. American journal of physiology. Regulatory, integrative and comparative physiology, 2017.
  55. Calais J, Czernin J, Eiber M, Fendler WP, Gartmann J, Heaney AP, Hendifar AE, Pisegna JR, Hecht JR, Wolin EM, Slavik R, Gupta P, Quon A, Schiepers C, Allen-Auerbach MS, Herrmann K. Most of the Intended Management Changes After 68Ga-DOTATATE PET/CT Are Implemented.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017.
  56. Wang J, Benhammou JN, Ghassemi K, Kim S, Sedarat A, Farrell J, Pisegna JR. Endoscopic Ultrasound-Guided Fine Needle Aspiration Accurately Diagnoses Smaller Pancreatic Neuroendocrine Tumors Compared To Computer Tomography-Guided Fine Needle Aspiration.. Journal of gastroenterology, pancreatology & liver disorders, 2017.
  57. Li R, Yang J, Saffari A, Jacobs J, Baek KI, Hough G, Larauche MH, Ma J, Jen N, Moussaoui N, Zhou B, Kang H, Reddy S, Henning SM, Campen MJ, Pisegna J, Li Z, Fogelman AM, Sioutas C, Navab M, Hsiai TK. Ambient Ultrafine Particle Ingestion Alters Gut Microbiota in Association with Increased Atherogenic Lipid Metabolites.. Scientific reports, 2017.
  58. Minalyan A, Benhammou JN, Artashesyan A, Lewis MS, Pisegna JR. Autoimmune atrophic gastritis: current perspectives.. Clinical and experimental gastroenterology, 2017.
  59. Benhammou JN, Phan J, Lee H, Ghassemi K, Parsons W, Grody WW, Pisegna JR. A Sodium Channel Myotonia Presenting with Intermittent Dysphagia as a Manifestation of a Rare SCN4A Variant.. Journal of molecular neuroscience : MN, 2016.
  60. Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation.. American journal of physiology. Gastrointestinal and liver physiology, 2016.
  61. Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis.. Journal of molecular neuroscience : MN, 2015.
  62. Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management.. Current treatment options in gastroenterology, 2015.
  63. Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin.. American journal of physiology. Gastrointestinal and liver physiology, 2015.
  64. Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP).. Journal of molecular neuroscience : MN, 2015.
  65. Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice.. Journal of molecular neuroscience : MN, 2014.
  66. Stengel A, Goebel-Stengel M, Wang L, Hu E, Karasawa H, Pisegna JR, Taché Y. High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats.. American journal of physiology. Regulatory, integrative and comparative physiology, 2013.
  67. Wang HS, Pisegna J, Modi R, Liang LJ, Atia M, Nguyen M, Cohen H, Ohning G, van Oijen M, Spiegel BM. Adenoma detection rate is necessary but insufficient for distinguishing high versus low endoscopist performance.. Gastrointestinal endoscopy, 2013.
  68. Harmar AJ, Fahrenkrug J, Gozes I, Laburthe M, May V, Pisegna JR, Vaudry D, Vaudry H, Waschek JA, Said SI. Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.. British journal of pharmacology, 2012.
  69. Vu JP, Wang HS, Germano PM, Pisegna JR. Ghrelin in neuroendocrine tumors.. Peptides, 2011.
  70. Pisegna JR, Surti B, Scott DR. Clinical trial report: Eradication of Helicobacter pylori reduces the risk for subsequent gastric cancer.. Current gastroenterology reports, 2010.
  71. Lu Y, Germano P, Ohning GV, Vu JP, Pisegna JR. PAC1 deficiency in a murine model induces gastric mucosa hypertrophy and higher basal gastric acid output.. Journal of molecular neuroscience : MN, 2010.
  72. Pisegna JR. Do COX-2 inhibitors reduce metachronous cancer development?. Current gastroenterology reports, 2009.
  73. Germano PM, Lieu SN, Xue J, Cooke HJ, Christofi FL, Lu Y, Pisegna JR. PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells.. Journal of molecular neuroscience : MN, 2009.
  74. Kohan E, Oh D, Wang H, Hazany S, Ohning G, Pisegna JR. Duodenal bulb mucosa with hypertrophic gastric oxyntic heterotopia in patients with zollinger ellison syndrome.. Diagnostic and therapeutic endoscopy, 2009.
  75. Pisegna JR. Is surveillance upper endoscopy indicated for gastric ulcers?. Current gastroenterology reports, 2008.
  76. Pisegna JR, Karlstadt RG, Norton JA, Fogel R, Oh DS, Jay Graepel G, Dorr MB. Effect of preoperative intravenous pantoprazole in elective-surgery patients: a pilot study.. Digestive diseases and sciences, 2008.
  77. Wang HS, Oh DS, Anderson A, Nieto J, Tien P, Ohning G, Pisegna JR. Comparative efficacy of rabeprazole and pantoprazole in the control of nocturnal Acid output and intragastric acidity.. Gut and liver, 2008.
  78. Pisegna JR, Sostek MB, Monyak JT, Miner PB. Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults.. Alimentary pharmacology & therapeutics, 2007.
  79. Metz DC, Sostek MB, Ruszniewski P, Forsmark CE, Monyak J, Pisegna JR. Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion.. The American journal of gastroenterology, 2007.
  80. Wang HS, Oh DS, Ohning GV, Pisegna JR. Elevated serum ghrelin exerts an orexigenic effect that may maintain body mass index in patients with metastatic neuroendocrine tumors.. Journal of molecular neuroscience : MN, 2007.
  81. Pisegna JR, Oh DS. Pituitary adenylate cyclase-activating polypeptide: a novel peptide with protean implications.. Current opinion in endocrinology, diabetes, and obesity, 2007.
  82. Wang HS, Oh DS, Ohning GV, Pisegna JR. Cyto-reduction of neuroendocrine tumours using Sandostatin LAR in combination with Infergen: results of a case series.. The Journal of pharmacy and pharmacology, 2006.
  83. Oh DS, Wang HS, Ohning GV, Pisegna JR. Validation of a new endoscopic technique to assess acid output in Zollinger-Ellison syndrome.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006.
  84. Lieu SN, Oh DS, Pisegna JR, Germano PM. Neuroendocrine tumors express PAC1 receptors.. Annals of the New York Academy of Sciences, 2006.
  85. Nieto JM, Pisegna JR. The role of proton pump inhibitors in the treatment of Zollinger-Ellison syndrome.. Expert opinion on pharmacotherapy, 2006.
  86. Oh DS, Ohning GV, Pisegna JR. Rabeprazole controls GERD symptoms in a patient for whom treatment with lansoprazole failed: first report of "cluster GERD.".. Digestive diseases and sciences, 2005.
  87. Pisegna JR, Martindale RG. Acid suppression in the perioperative period.. Journal of clinical gastroenterology, 2005.
  88. Oh DS, Lieu SN, Yamaguchi DJ, Tachiki K, Lambrecht N, Ohning GV, Sachs G, Germano PM, Pisegna JR. PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells.. Journal of molecular neuroscience : MN, 2005.
  89. Pisegna J, Holtmann G, Howden CW, Katelaris PH, Sharma P, Spechler S, Triadafilopoulos G, Tytgat G. Review article: oesophageal complications and consequences of persistent gastro-oesophageal reflux disease.. Alimentary pharmacology & therapeutics, 2004.
  90. Weinberg BM, Oh DS, Ohning GV, Pisegna JR. Reflux laryngitis in a patient with Zollinger Ellison syndrome and the role of epidermal growth factor.. Digestive diseases and sciences, 2004.
  91. Germano PM, Le SV, Oh DS, Fan R, Lieu S, Siu A, Pisegna JR. Differential coupling of the PAC1 SV1 splice variant on human colonic tumors to the activation of intracellular cAMP but not intracellular Ca2+ does not activate tumor proliferation.. Journal of molecular neuroscience : MN, 2004.
  92. Pisegna JR. Treating patients with acute gastrointestinal bleeding or rebleeding.. Pharmacotherapy, 2003.
  93. Friedlander AH, Marder SR, Pisegna JR, Yagiela JA. Alcohol abuse and dependence: psychopathology, medical management and dental implications.. Journal of the American Dental Association (1939), 2003.
  94. Oh DS, Pisegna JR. Pharmacologic Treatment of Upper Gastrointestinal Bleeding.. Current treatment options in gastroenterology, 2003.
  95. Metz DC, Soffer E, Forsmark CE, Cryer B, Chey W, Bochenek W, Pisegna JR. Maintenance oral pantoprazole therapy is effective for patients with Zollinger-Ellison syndrome and idiopathic hypersecretion.. The American journal of gastroenterology, 2003.
  96. Le SV, Yamaguchi DJ, McArdle CA, Tachiki K, Pisegna JR, Germano P. PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells.. Regulatory peptides, 2002.
  97. Metz DC, Ferron GM, Paul J, Turner MB, Soffer E, Pisegna JR, Bochenek WJ. Proton pump activation in stimulated parietal cells is regulated by gastric acid secretory capacity: a human study.. Journal of clinical pharmacology, 2002.
  98. Tang SJ, Tran T, Memmesheimer C, Pandol S, Aranda R, Pisegna JR, Jensen DM. Paraesophageal hernia repair and deep vein thrombosis.. Journal of clinical gastroenterology, 2002.
  99. Tang SJ, Nieto JM, Jensen DM, Ohning GV, Pisegna JR. The novel use of an intravenous proton pump inhibitor in a patient with short bowel syndrome.. Journal of clinical gastroenterology, 2002.
  100. Pisegna JR. GERD and its complications. The pathogenic relationship between symptoms and disease progression.. Postgraduate medicine, 2001.
  101. Pisegna JR. Switching between intravenous and oral pantoprazole.. Journal of clinical gastroenterology, 2001.