Juli F Feigon
Professor, Chemistry and Biochemistry, University of California Los Angeles
feigon@mbi.ucla.edu
1 (310) 825-9232
Education and Training
Massachusetts Institute of Technology | Postdoc | 1985 | Biology |
University of California, San DIego | PhD | 1982 | Chemistry |
Occidental College | BA | 1976 | Chemistry |
Publications
- Yang Y, Murrali MG, Wang Y, Galvan S, Ajjampore N, Feigon J. HEXIM1 homodimer binds two sites on 7SK RNA to release autoinhibition for P-TEFb inactivation.. bioRxiv : the preprint server for biology, 2024.
- Eisenberg D, Hou K, Ge P, Sawaya M, Dolinsky J, Yang Y, Jiang YX, Lutter L, Boyer D, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J. How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.. Research square, 2024.
- Hou K, Ge P, Sawaya MR, Dolinsky JL, Yang Y, Jiang YX, Lutter L, Boyer DR, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J, Eisenberg DS. How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.. bioRxiv : the preprint server for biology, 2024.
- Palumbo RJ, Yang Y, Feigon J, Hanes SD. Catalytic activity of the Bin3/MePCE methyltransferase domain is dispensable for 7SK snRNP function in Drosophila melanogaster.. Genetics, 2024.
- Wang Y, He Y, Wang Y, Yang Y, Singh M, Eichhorn CD, Cheng X, Jiang YX, Zhou ZH, Feigon J. Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.. Journal of molecular biology, 2023.
- He Y, Feigon J. Telomerase structural biology comes of age.. Current opinion in structural biology, 2022.
- He Y, Song H, Chan H, Liu B, Wang Y, Sušac L, Zhou ZH, Feigon J. Structure of Tetrahymena telomerase-bound CST with polymerase α-primase.. Nature, 2022.
- Liu B, He Y, Wang Y, Song H, Zhou ZH, Feigon J. Structure of active human telomerase with telomere shelterin protein TPP1.. Nature, 2022.
- Yang Y, Liu S, Egloff S, Eichhorn CD, Hadjian T, Zhen J, Kiss T, Zhou ZH, Feigon J. Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.. Molecular cell, 2022.
- He Y, Wang Y, Liu B, Helmling C, Sušac L, Cheng R, Zhou ZH, Feigon J. Structures of telomerase at several steps of telomere repeat synthesis.. Nature, 2021.
- Wang Y, Gallagher-Jones M, Sušac L, Song H, Feigon J. A structurally conserved human and Tetrahymena telomerase catalytic core.. Proceedings of the National Academy of Sciences of the United States of America, 2020.
- Basu R, Eichhorn CD, Cheng R, Peterson RD, Feigon J. Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins.. RNA biology, 2020.
- Wang Y, Sušac L, Feigon J. Structural Biology of Telomerase.. Cold Spring Harbor perspectives in biology, 2019.
- Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J. Structural basis of 7SK RNA 5'-γ-phosphate methylation and retention by MePCE.. Nature chemical biology, 2018.
- Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Author Correction: Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.. Nature chemistry, 2018.
- Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.. Nature chemistry, 2018.
- Eichhorn CD, Yang Y, Repeta L, Feigon J. Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.. Proceedings of the National Academy of Sciences of the United States of America, 2018.
- Jiang J, Wang Y, Sušac L, Chan H, Basu R, Zhou ZH, Feigon J. Structure of Telomerase with Telomeric DNA.. Cell, 2018.
- Wang Y, Feigon J. Structural biology of telomerase and its interaction at telomeres.. Current opinion in structural biology, 2017.
- Chan H, Wang Y, Feigon J. Progress in Human and Tetrahymena Telomerase Structure Determination.. Annual review of biophysics, 2017.
- Cash DD, Feigon J. Structure and folding of the Tetrahymena telomerase RNA pseudoknot.. Nucleic acids research, 2016.
- Upton HE, Chan H, Feigon J, Collins K. Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes.. The Journal of biological chemistry, 2016.
- Eichhorn CD, Chug R, Feigon J. hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.. Nucleic acids research, 2016.
- Wang Y, Yesselman JD, Zhang Q, Kang M, Feigon J. Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human.. Proceedings of the National Academy of Sciences of the United States of America, 2016.
- Feigon J, Chan H, Jiang J. Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres.. The FEBS journal, 2016.
- Jiang J, Chan H, Cash DD, Miracco EJ, Ogorzalek Loo RR, Upton HE, Cascio D, O'Brien Johnson R, Collins K, Loo JA, Zhou ZH, Feigon J. Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.. Science (New York, N.Y.), 2015.
- Feigon J. Back to the future of RNA structure.. RNA (New York, N.Y.), 2015.
- Singh M, Wang Z, Cascio D, Feigon J. Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.. Journal of molecular biology, 2014.
- Eichhorn CD, Kang M, Feigon J. Structure and function of preQ1 riboswitches.. Biochimica et biophysica acta, 2014.
- Miracco EJ, Jiang J, Cash DD, Feigon J. Progress in structural studies of telomerase.. Current opinion in structural biology, 2014.
- Kang M, Eichhorn CD, Feigon J. Structural determinants for ligand capture by a class II preQ1 riboswitch.. Proceedings of the National Academy of Sciences of the United States of America, 2014.
- Kim NK, Zhang Q, Feigon J. Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function.. Nucleic acids research, 2013.
- Shen K, Wang Y, Hwang Fu YH, Zhang Q, Feigon J, Shan SO. Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end.. The Journal of biological chemistry, 2013.
- Hong K, Upton H, Miracco EJ, Jiang J, Zhou ZH, Feigon J, Collins K. Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub.. Molecular and cellular biology, 2013.
- Cash DD, Cohen-Zontag O, Kim NK, Shefer K, Brown Y, Ulyanov NB, Tzfati Y, Feigon J. Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo.. Proceedings of the National Academy of Sciences of the United States of America, 2013.
- Jiang J, Miracco EJ, Hong K, Eckert B, Chan H, Cash DD, Min B, Zhou ZH, Collins K, Feigon J. The architecture of Tetrahymena telomerase holoenzyme.. Nature, 2013.
- Singh M, Choi CP, Feigon J. xRRM: a new class of RRM found in the telomerase La family protein p65.. RNA biology, 2013.
- Hartman E, Wang Z, Zhang Q, Roy K, Chanfreau G, Feigon J. Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites.. Journal of molecular biology, 2012.
- Kang M, Heuberger B, Chaput JC, Switzer C, Feigon J. Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4 T) in the presence of Cs+ ions.. Angewandte Chemie (International ed. in English), 2012.
- Singh M, Wang Z, Koo BK, Patel A, Cascio D, Collins K, Feigon J. Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65.. Molecular cell, 2012.
- Hengesbach M, Kim NK, Feigon J, Stone MD. Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain.. Angewandte Chemie (International ed. in English), 2012.
- Zhang Q, Kim NK, Feigon J. Architecture of human telomerase RNA.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
- Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J. Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs.. Structure (London, England : 1993), 2011.
- Koo BK, Park CJ, Fernandez CF, Chim N, Ding Y, Chanfreau G, Feigon J. Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.. Journal of molecular biology, 2011.
- Zhang Q, Kang M, Peterson RD, Feigon J. Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics.. Journal of the American Chemical Society, 2011.
- Zhang Q, Kim NK, Peterson RD, Wang Z, Feigon J. Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA.. Proceedings of the National Academy of Sciences of the United States of America, 2010.
- Kim NK, Theimer CA, Mitchell JR, Collins K, Feigon J. Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA.. Nucleic acids research, 2010.
- Kang M, Peterson R, Feigon J. Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA.. Molecular cell, 2009.
- Singh M, Gonzales FA, Cascio D, Heckmann N, Chanfreau G, Feigon J. Structure and functional studies of the CS domain of the essential H/ACA ribonucleoparticle assembly protein SHQ1.. The Journal of biological chemistry, 2008.
- Kim NK, Zhang Q, Zhou J, Theimer CA, Peterson RD, Feigon J. Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA.. Journal of molecular biology, 2008.
- Theimer CA, Jády BE, Chim N, Richard P, Breece KE, Kiss T, Feigon J. Structural and functional characterization of human telomerase RNA processing and cajal body localization signals.. Molecular cell, 2007.
- Januszyk K, Li PW, Villareal V, Branciforte D, Wu H, Xie Y, Feigon J, Loo JA, Martin SL, Clubb RT. Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1.. The Journal of biological chemistry, 2007.
- Wu H, Feigon J. H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.. Proceedings of the National Academy of Sciences of the United States of America, 2007.
- Richards RJ, Wu H, Trantirek L, O'Connor CM, Collins K, Feigon J. Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function.. RNA (New York, N.Y.), 2006.
- Theimer CA, Feigon J. Structure and function of telomerase RNA.. Current opinion in structural biology, 2006.
- Richards RJ, Theimer CA, Finger LD, Feigon J. Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element.. Nucleic acids research, 2006.
- Khanna M, Wu H, Johansson C, Caizergues-Ferrer M, Feigon J. Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.. RNA (New York, N.Y.), 2006.
- Dingley AJ, Peterson RD, Grzesiek S, Feigon J. Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR.. Journal of the American Chemical Society, 2005.
- Qin PZ, Feigon J, Hubbell WL. Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop.. Journal of molecular biology, 2005.
- Henras AK, Sam M, Hiley SL, Wu H, Hughes TR, Feigon J, Chanfreau GF. Biochemical and genomic analysis of substrate recognition by the double-stranded RNA binding domain of yeast RNase III.. RNA (New York, N.Y.), 2005.
- Theimer CA, Blois CA, Feigon J. Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function.. Molecular cell, 2005.
- Wu H, Finger LD, Feigon J. Structure determination of protein/RNA complexes by NMR.. Methods in enzymology, 2005.
- Kamionka M, Feigon J. Structure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction.. Protein science : a publication of the Protein Society, 2004.
- Finger LD, Johansson C, Rinaldi B, Bouvet P, Feigon J. Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction.. Biochemistry, 2004.
- Wu H, Henras A, Chanfreau G, Feigon J. Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.. Proceedings of the National Academy of Sciences of the United States of America, 2004.
- Johansson C, Finger LD, Trantirek L, Mueller TD, Kim S, Laird-Offringa IA, Feigon J. Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.. Journal of molecular biology, 2004.
- Stefl R, Wu H, Ravindranathan S, Sklenár V, Feigon J. DNA A-tract bending in three dimensions: solving the dA4T4 vs. dT4A4 conundrum.. Proceedings of the National Academy of Sciences of the United States of America, 2004.
- Mueller TD, Kamionka M, Feigon J. Specificity of the interaction between ubiquitin-associated domains and ubiquitin.. The Journal of biological chemistry, 2004.
- Peterson RD, Theimer CA, Wu H, Feigon J. New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes.. Journal of biomolecular NMR, 2004.
- Theimer CA, Finger LD, Feigon J. YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.. RNA (New York, N.Y.), 2003.
- Finger LD, Trantirek L, Johansson C, Feigon J. Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin.. Nucleic acids research, 2003.
- Mueller TD, Feigon J. Structural determinants for the binding of ubiquitin-like domains to the proteasome.. The EMBO journal, 2003.
- Qin PZ, Hideg K, Feigon J, Hubbell WL. Monitoring RNA base structure and dynamics using site-directed spin labeling.. Biochemistry, 2003.
- Theimer CA, Finger LD, Trantirek L, Feigon J. Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA.. Proceedings of the National Academy of Sciences of the United States of America, 2003.
- Masse JE, Wong B, Yen YM, Allain FH, Johnson RC, Feigon J. The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding.. Journal of molecular biology, 2002.
- Hud NV, Feigon J. Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II).. Biochemistry, 2002.
- Mueller TD, Feigon J. Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions.. Journal of molecular biology, 2002.
- Trantírek L, Stefl R, Masse JE, Feigon J, Sklenár V. Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'.. Journal of biomolecular NMR, 2002.
- Wong B, Masse JE, Yen YM, Giannikopoulos P, Feigon J, Johnson RC, Giannikoupolous P. Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.. Biochemistry, 2002.
- Wu H, Yang PK, Butcher SE, Kang S, Chanfreau G, Feigon J. A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.. The EMBO journal, 2001.
- Zídek L, Wu H, Feigon J, Sklenár V. Measurement of small scalar and dipolar couplings in purine and pyrimidine bases.. Journal of biomolecular NMR, 2001.
- Qin PZ, Butcher SE, Feigon J, Hubbell WL. Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study.. Biochemistry, 2001.
- Bouvet P, Allain FH, Finger LD, Dieckmann T, Feigon J. Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin.. Journal of molecular biology, 2001.
- Barfield M, Dingley AJ, Feigon J, Grzesiek S. A DFT study of the interresidue dependencies of scalar J-coupling and magnetic shielding in the hydrogen-bonding regions of a DNA triplex.. Journal of the American Chemical Society, 2001.
- Feigon J, Butcher SE, Finger LD, Hud NV. Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids.. Methods in enzymology, 2001.
- Ravindranathan S, Butcher SE, Feigon J. Adenine protonation in domain B of the hairpin ribozyme.. Biochemistry, 2000.
- Allain FH, Bouvet P, Dieckmann T, Feigon J. Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.. The EMBO journal, 2000.
- Withers-Ward ES, Mueller TD, Chen IS, Feigon J. Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr.. Biochemistry, 2000.
- Allain FH, Gilbert DE, Bouvet P, Feigon J. Solution structure of the two N-terminal RNA-binding domains of nucleolin and NMR study of the interaction with its RNA target.. Journal of molecular biology, 2000.
- Dingley AJ, Masse JE, Feigon J, Grzesiek S. Characterization of the hydrogen bond network in guanosine quartets by internucleotide 3hJ(NC)' and 2hJ(NN) scalar couplings.. Journal of biomolecular NMR, 2000.
- Butcher SE, Allain FH, Feigon J. Determination of metal ion binding sites within the hairpin ribozyme domains by NMR.. Biochemistry, 2000.
- Schultze P, Hud NV, Smith FW, Feigon J. The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)).. Nucleic acids research, 1999.
- Gilbert DE, Feigon J. Multistranded DNA structures.. Current opinion in structural biology, 1999.
- Allain FH, Yen YM, Masse JE, Schultze P, Dieckmann T, Johnson RC, Feigon J. Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.. The EMBO journal, 1999.
- Sklenár V, Masse JE, Feigon J. HCCCH experiment for through-bond correlation of thymine resonances in 13C-labeled DNA oligonucleotides.. Journal of magnetic resonance (San Diego, Calif. : 1997), 1999.
- Butcher SE, Allain FH, Feigon J. Solution structure of the loop B domain from the hairpin ribozyme.. Nature structural biology, 1999.
- Hud NV, Sklenár V, Feigon J. Localization of ammonium ions in the minor groove of DNA duplexes in solution and the origin of DNA A-tract bending.. Journal of molecular biology, 1999.
- Hud NV, Schultze P, Sklenár V, Feigon J. Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex.. Journal of molecular biology, 1999.
- Dieckmann T, Withers-Ward ES, Jarosinski MA, Liu CF, Chen IS, Feigon J. Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr.. Nature structural biology, 1998.
- Masse JE, Bortmann P, Dieckmann T, Feigon J. Simple, efficient protocol for enzymatic synthesis of uniformly 13C, 15N-labeled DNA for heteronuclear NMR studies.. Nucleic acids research, 1998.
- Phipps AK, Tarköy M, Schultze P, Feigon J. Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2'-deoxyuridine residues in the third strand.. Biochemistry, 1998.
- Tarköy M, Phipps AK, Schultze P, Feigon J. Solution structure of an intramolecular DNA triplex linked by hexakis(ethylene glycol) units: d(AGAGAGAA-(EG)6-TTCTCTCT-(EG)6-TCTCTCTT).. Biochemistry, 1998.
- Sklenár V, Dieckmann T, Butcher SE, Feigon J. Optimization of triple-resonance HCN experiments for application to larger RNA oligonucleotides.. Journal of magnetic resonance (San Diego, Calif. : 1997), 1998.
- Butcher SE, Dieckmann T, Feigon J. Solution structure of a GAAA tetraloop receptor RNA.. The EMBO journal, 1997.
- Dieckmann T, Butcher SE, Sassanfar M, Szostak JW, Feigon J. Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding.. Journal of molecular biology, 1997.
- Uhlenbeck OC, Pardi A, Feigon J. RNA structure comes of age.. Cell, 1997.
- Butcher SE, Dieckmann T, Feigon J. Solution structure of the conserved 16 S-like ribosomal RNA UGAA tetraloop.. Journal of molecular biology, 1997.
- Dieckmann T, Feigon J. Assignment methodology for larger RNA oligonucleotides: application to an ATP-binding RNA aptamer.. Journal of biomolecular NMR, 1997.
- Koshlap KM, Schultze P, Brunar H, Dervan PB, Feigon J. Solution structure of an intramolecular DNA triplex containing an N7-glycosylated guanine which mimics a protonated cytosine.. Biochemistry, 1997.
- Peterson RD, Feigon J. Structural change in Rev responsive element RNA of HIV-1 on binding Rev peptide.. Journal of molecular biology, 1996.
- Hud NV, Smith FW, Anet FA, Feigon J. The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR.. Biochemistry, 1996.
- Feigon J, Dieckmann T, Smith FW. Aptamer structures from A to zeta.. Chemistry & biology, 1996.
- Dieckmann T, Suzuki E, Nakamura GK, Feigon J. Solution structure of an ATP-binding RNA aptamer reveals a novel fold.. RNA (New York, N.Y.), 1996.
- Fahrner RL, Dieckmann T, Harwig SS, Lehrer RI, Eisenberg D, Feigon J. Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes.. Chemistry & biology, 1996.
- Wang E, Koshlap KM, Gillespie P, Dervan PB, Feigon J. Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3.. Journal of molecular biology, 1996.
- Kelly JA, Feigon J, Yeates TO. Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG).. Journal of molecular biology, 1996.
- Sklenár V, Dieckmann T, Butcher SE, Feigon J. Through-bond correlation of imino and aromatic resonances in 13C-, 15N-labeled RNA via heteronuclear TOCSY.. Journal of biomolecular NMR, 1996.
- Smith FW, Schultze P, Feigon J. Solution structures of unimolecular quadruplexes formed by oligonucleotides containing Oxytricha telomere repeats.. Structure (London, England : 1993), 1995.
- Schneider DJ, Feigon J, Hostomsky Z, Gold L. High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus.. Biochemistry, 1995.
- Feigon J, Koshlap KM, Smith FW. 1H NMR spectroscopy of DNA triplexes and quadruplexes.. Methods in enzymology, 1995.
- Addess KJ, Feigon J. NMR investigation of Hoogsteen base pairing in quinoxaline antibiotic--DNA complexes: comparison of 2:1 echinomycin, triostin A and [N-MeCys3,N-MeCys7] TANDEM complexes with DNA oligonucleotides.. Nucleic acids research, 1994.
- Smith FW, Lau FW, Feigon J. d(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformations.. Proceedings of the National Academy of Sciences of the United States of America, 1994.
- Addess KJ, Feigon J. Sequence specificity of quinoxaline antibiotics. 1. Solution structure of a 1:1 complex between triostin A and [d(GACGTC)]2 and comparison with the solution structure of the [N-MeCys3,N-MeCys7]TANDEM-[d(GATATC)]2 complex.. Biochemistry, 1994.
- Addess KJ, Feigon J. Sequence specificity of quinoxaline antibiotics. 2. NMR studies of the binding of [N-MeCys3,N-MeCys7]TANDEM and triostin A to DNA containing a CpI step.. Biochemistry, 1994.
- Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J. 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element.. Biochemistry, 1994.
- Schultze P, Smith FW, Feigon J. Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG).. Structure (London, England : 1993), 1994.
- Schultze P, Macaya RF, Feigon J. Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG).. Journal of molecular biology, 1994.
- Sklenár V, Peterson RD, Rejante MR, Feigon J. Correlation of nucleotide base and sugar protons in a 15N-labeled HIV-1 RNA oligonucleotide by 1H-15N HSQC experiments.. Journal of biomolecular NMR, 1994.
- Sklenár V, Peterson RD, Rejante MR, Feigon J. Two- and three-dimensional HCN experiments for correlating base and sugar resonances in 15N,13C-labeled RNA oligonucleotides.. Journal of biomolecular NMR, 1993.
- Feigon J. A new DNA quadruplex.. Current biology : CB, 1993.
- Smith FW, Feigon J. Strand orientation in the DNA quadruplex formed from the Oxytricha telomere repeat oligonucleotide d(G4T4G4) in solution.. Biochemistry, 1993.
- Macaya RF, Schultze P, Smith FW, Roe JA, Feigon J. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution.. Proceedings of the National Academy of Sciences of the United States of America, 1993.
- Addess KJ, Sinsheimer JS, Feigon J. Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2.. Biochemistry, 1993.
- Macaya R, Wang E, Schultze P, Sklenár V, Feigon J. Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex.. Journal of molecular biology, 1992.
- Wang E, Malek S, Feigon J. Structure of a G.T.A triplet in an intramolecular DNA triplex.. Biochemistry, 1992.
- Gilbert DE, Feigon J. Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites.. Nucleic acids research, 1992.
- Smith FW, Feigon J. Quadruplex structure of Oxytricha telomeric DNA oligonucleotides.. Nature, 1992.
- Addess KJ, Gilbert DE, Olsen RK, Feigon J. Proton NMR studies of [N-MeCys3,N-MeCys7]TANDEM binding to DNA oligonucleotides: sequence-specific binding at the TpA site.. Biochemistry, 1992.
- Feigon J, Sklenár V, Wang E, Gilbert DE, Macaya RF, Schultze P. 1H NMR spectroscopy of DNA.. Methods in enzymology, 1992.
- Macaya RF, Gilbert DE, Malek S, Sinsheimer JS, Feigon J. Structure and stability of X.G.C mismatches in the third strand of intramolecular triplexes.. Science (New York, N.Y.), 1991.
- Gilbert DE, Feigon J. The DNA sequence at echinomycin binding sites determines the structural changes induced by drug binding: NMR studies of echinomycin binding to [d(ACGTACGT)]2 and [d(TCGATCGA)]2.. Biochemistry, 1991.
- Sklenár V, Feigon J. Formation of a stable triplex from a single DNA strand.. Nature, 1990.
- Hua N, van der Marel GA, van Boom JH, Feigon J. Non-contiguous regions of Z-DNA in a DNA dodecamer.. Nucleic acids research, 1989.
- Rajagopal P, Feigon J. NMR studies of triple-strand formation from the homopurine-homopyrimidine deoxyribonucleotides d(GA)4 and d(TC)4.. Biochemistry, 1989.
- Rajagopal P, Feigon J. Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4.. Nature, 1989.
- Gilbert DE, van der Marel GA, van Boom JH, Feigon J. Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.. Proceedings of the National Academy of Sciences of the United States of America, 1989.
- Ellison MJ, Feigon J, Kelleher RJ, Wang AH, Habener JF, Rich A. An assessment of the Z-DNA forming potential of alternating dA-dT stretches in supercoiled plasmids.. Biochemistry, 1986.
- Feigon J, Wang AH, van der Marel GA, Van Boom JH, Rich A. A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution.. Nucleic acids research, 1984.
- Feigon J, Denny WA, Leupin W, Kearns DR. Proton nuclear magnetic resonance investigation of the conformation and dynamics in the synthetic deoxyribonucleic acid decamers d(ATATCGATAT) and d(ATATGCATAT).. Biochemistry, 1983.
- Feigon J, Leupin W, Denny WA, Kearns DR. Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2.. Biochemistry, 1983.
- Feigon J, Wright JM, Denny WA, Leupin W, Kearns DR. Application of multiple-pulse H-NMR techniques to the study of two synthetic DNA decamers.. Cold Spring Harbor symposia on quantitative biology, 1983.
- Feigon J, Leupin W, Denny WA, Kearns DR. Binding of ethidium derivatives to natural DNA: a 300 MHz 1H NMR study.. Nucleic acids research, 1982.
- Granot J, Feigon J, Kearns DR. Interactions of DNA with divalent metal ions. I. 31P-NMR studies.. Biopolymers, 1982.
- Feigon J, Kearns DR. 1H NMR investigation of the conformational states of DNA in nucleosome core particles.. Nucleic acids research, 1979.