Publications

1. González VV, Malvaez M, Yeghikian A, Wissing S, Sharpe M, Wassum KM, Izquierdo A. A Common Stay-on-Goal Mechanism in the Anterior Cingulate Cortex for Information and Effort Choices.. eNeuro, 2025.
2. Meredith LR, Baskerville WA, Lee C, Grodin EN, Wassum KM, Ray LA. Correction to: Infuence of real-world cue exposure and mood states on drinking: testing neurobiological models of alcohol use disorder.. Psychopharmacology, 2025.
3. Giovanniello JR, Paredes N, Wiener A, Ramírez-Armenta K, Oragwam C, Uwadia HO, Yu AL, Lim K, Pimenta JS, Vilchez GE, Nnamdi G, Wang A, Sehgal M, Reis FM, Sias AC, Silva AJ, Adhikari A, Malvaez M, Wassum KM. A dual-pathway architecture for stress to disrupt agency and promote habit.. Nature, 2025.
4. Meredith LR, Baskerville WA, Lee C, Grodin EN, Wassum KM, Ray LA. Influence of real-world cue exposure and mood states on drinking: testing neurobiological models of alcohol use disorder.. Psychopharmacology, 2025.
5. Malvaez M, Liang A, Hall BS, Giovanniello JR, Paredes N, Gonzalez JY, Blair GJ, Sias AC, Murphy MD, Guo W, Wang A, Singh M, Griffin NK, Bridges SP, Wiener A, Pimenta JS, Holley SM, Cepeda C, Levine MS, Blair HT, Wikenheiser AM, Wassum KM. Striatal cell-type specific stability and reorganization underlying agency and habit.. bioRxiv : the preprint server for biology, 2025.
6. Giovanniello JR, Paredes N, Wiener A, Ramírez-Armenta K, Oragwam C, Uwadia HO, Yu AL, Lim K, Pimenta JS, Vilchez GE, Nnamdi G, Wang A, Sehgal M, Reis FM, Sias AC, Silva AJ, Adhikari A, Malvaez M, Wassum KM. A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation.. bioRxiv : the preprint server for biology, 2024.
7. Millard SJ, Hoang IB, Sherwood S, Taira M, Reyes V, Greer Z, O'Connor SL, Wassum KM, James MH, Barker DJ, Sharpe MJ. Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency.. Nature neuroscience, 2024.
8. Movassaghi CS, Alcañiz Fillol M, Kishida KT, McCarty G, Sombers LA, Wassum KM, Andrews AM. Maximizing Electrochemical Information: A Perspective on Background-Inclusive Fast Voltammetry.. Analytical chemistry, 2024.
9. Sias AC, Jafar Y, Goodpaster CM, Ramírez-Armenta K, Wrenn TM, Griffin NK, Patel K, Lamparelli AC, Sharpe MJ, Wassum KM. Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories.. Nature neuroscience, 2024.
10. Kirsch DE, Ray LA, Wassum KM, Grodin EN. Anterior cingulate and medial prefrontal cortex alcohol cue reactivity varies as a function of drink preference in alcohol use disorder.. Drug and alcohol dependence, 2024.
11. Halbout B, Hutson C, Wassum KM, Ostlund SB. Dorsomedial prefrontal cortex activation disrupts Pavlovian incentive motivation.. Frontiers in behavioral neuroscience, 2022.
12. Wassum KM. Amygdala-cortical collaboration in reward learning and decision making.. eLife, 2022.
13. Lichtenberg NT, Sepe-Forrest L, Pennington ZT, Lamparelli AC, Greenfield VY, Wassum KM. The Medial Orbitofrontal Cortex-Basolateral Amygdala Circuit Regulates the Influence of Reward Cues on Adaptive Behavior and Choice.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021.
14. Sias AC, Morse AK, Wang S, Greenfield VY, Goodpaster CM, Wrenn TM, Wikenheiser AM, Holley SM, Cepeda C, Levine MS, Wassum KM. A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories.. eLife, 2021.
15. Ray LA, Du H, Grodin E, Bujarski S, Meredith L, Ho D, Nieto S, Wassum K. Capturing habitualness of drinking and smoking behavior in humans.. Drug and alcohol dependence, 2019.
16. Halbout B, Marshall AT, Azimi A, Liljeholm M, Mahler SV, Wassum KM, Ostlund SB. Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats.. eLife, 2019.
17. Malvaez M, Shieh C, Murphy MD, Greenfield VY, Wassum KM. Distinct cortical-amygdala projections drive reward value encoding and retrieval.. Nature neuroscience, 2019.
18. Collins AL, Aitken TJ, Huang IW, Shieh C, Greenfield VY, Monbouquette HG, Ostlund SB, Wassum KM. Nucleus Accumbens Cholinergic Interneurons Oppose Cue-Motivated Behavior.. Biological psychiatry, 2019.
19. Wassum KM. Clarifying punishment.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018.
20. Malvaez M, Greenfield VY, Matheos DP, Angelillis NA, Murphy MD, Kennedy PJ, Wood MA, Wassum KM. Habits Are Negatively Regulated by Histone Deacetylase 3 in the Dorsal Striatum.. Biological psychiatry, 2018.
21. Malvaez M, Wassum KM. Regulation of habit formation in the dorsal striatum.. Current opinion in behavioral sciences, 2017.
22. Lichtenberg NT, Pennington ZT, Holley SM, Greenfield VY, Cepeda C, Levine MS, Wassum KM. Basolateral Amygdala to Orbitofrontal Cortex Projections Enable Cue-Triggered Reward Expectations.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017.
23. Hersman S, Cushman J, Lemelson N, Wassum K, Lotfipour S, Fanselow MS. Optogenetic excitation of cholinergic inputs to hippocampus primes future contextual fear associations.. Scientific reports, 2017.
24. Lichtenberg NT, Wassum KM. Amygdala mu-opioid receptors mediate the motivating influence of cue-triggered reward expectations.. The European journal of neuroscience, 2016.
25. Ostlund SB, Liu AT, Wassum KM, Maidment NT. Modulation of cue-triggered reward seeking by cholinergic signaling in the dorsomedial striatum.. The European journal of neuroscience, 2016.
26. Collins AL, Aitken TJ, Greenfield VY, Ostlund SB, Wassum KM. Nucleus Accumbens Acetylcholine Receptors Modulate Dopamine and Motivation.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016.
27. Malvaez M, Greenfield VY, Wang AS, Yorita AM, Feng L, Linker KE, Monbouquette HG, Wassum KM. Corrigendum: Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions.. Scientific reports, 2016.
28. Collins AL, Greenfield VY, Bye JK, Linker KE, Wang AS, Wassum KM. Dynamic mesolimbic dopamine signaling during action sequence learning and expectation violation.. Scientific reports, 2016.
29. Aitken TJ, Greenfield VY, Wassum KM. Nucleus accumbens core dopamine signaling tracks the need-based motivational value of food-paired cues.. Journal of neurochemistry, 2016.
30. Fanselow MS, Wassum KM. The Origins and Organization of Vertebrate Pavlovian Conditioning.. Cold Spring Harbor perspectives in biology, 2015.
31. Wassum KM, Izquierdo A. The basolateral amygdala in reward learning and addiction.. Neuroscience and biobehavioral reviews, 2015.
32. Malvaez M, Greenfield VY, Wang AS, Yorita AM, Feng L, Linker KE, Monbouquette HG, Wassum KM. Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions.. Scientific reports, 2015.
33. Wassum KM, Phillips PE. Probing the neurochemical correlates of motivation and decision making.. ACS chemical neuroscience, 2014.
34. Wassum KM, Greenfield VY, Linker KE, Maidment NT, Ostlund SB. Inflated reward value in early opiate withdrawal.. Addiction biology, 2014.
35. Ostlund SB, LeBlanc KH, Kosheleff AR, Wassum KM, Maidment NT. Phasic mesolimbic dopamine signaling encodes the facilitation of incentive motivation produced by repeated cocaine exposure.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014.
36. Wassum KM, Ostlund SB, Loewinger GC, Maidment NT. Phasic mesolimbic dopamine release tracks reward seeking during expression of Pavlovian-to-instrumental transfer.. Biological psychiatry, 2013.
37. Tolosa VM, Wassum KM, Maidment NT, Monbouquette HG. Electrochemically deposited iridium oxide reference electrode integrated with an electroenzymatic glutamate sensor on a multi-electrode array microprobe.. Biosensors & bioelectronics, 2012.
38. Wassum KM, Tolosa VM, Tseng TC, Balleine BW, Monbouquette HG, Maidment NT. Transient extracellular glutamate events in the basolateral amygdala track reward-seeking actions.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012.
39. Wassum KM, Ostlund SB, Maidment NT. Phasic mesolimbic dopamine signaling precedes and predicts performance of a self-initiated action sequence task.. Biological psychiatry, 2012.
40. Wassum KM, Ostlund SB, Balleine BW, Maidment NT. Differential dependence of Pavlovian incentive motivation and instrumental incentive learning processes on dopamine signaling.. Learning & memory (Cold Spring Harbor, N.Y.), 2011.
41. Wassum KM, Cely IC, Balleine BW, Maidment NT. Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011.
42. Ostlund SB, Wassum KM, Murphy NP, Balleine BW, Maidment NT. Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011.
43. Wassum KM, Cely IC, Maidment NT, Balleine BW. Disruption of endogenous opioid activity during instrumental learning enhances habit acquisition.. Neuroscience, 2009.
44. Wassum KM, Ostlund SB, Maidment NT, Balleine BW. Distinct opioid circuits determine the palatability and the desirability of rewarding events.. Proceedings of the National Academy of Sciences of the United States of America, 2009.
45. Wassum KM, Evans CJ. International Narcotics Research Conference - 39th Annual Meeting.. IDrugs : the investigational drugs journal, 2008.
46. Wassum KM, Tolosa VM, Wang J, Walker E, Monbouquette HG, Maidment NT. Silicon Wafer-Based Platinum Microelectrode Array Biosensor for Near Real-Time Measurement of Glutamate in Vivo.. Sensors (Basel, Switzerland), 2008.
47. Wightman RM, Heien ML, Wassum KM, Sombers LA, Aragona BJ, Khan AS, Ariansen JL, Cheer JF, Phillips PE, Carelli RM. Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens.. The European journal of neuroscience, 2007.
48. Cheer JF, Wassum KM, Sombers LA, Heien ML, Ariansen JL, Aragona BJ, Phillips PE, Wightman RM. Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007.
49. Cheer JF, Wassum KM, Wightman RM. Cannabinoid modulation of electrically evoked pH and oxygen transients in the nucleus accumbens of awake rats.. Journal of neurochemistry, 2006.
50. Heien ML, Khan AS, Ariansen JL, Cheer JF, Phillips PE, Wassum KM, Wightman RM. Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats.. Proceedings of the National Academy of Sciences of the United States of America, 2005.
51. Cheer JF, Wassum KM, Heien ML, Phillips PE, Wightman RM. Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004.