Loes Marlein Olde Loohuis
Assistant Professor-in-Residence, Psychiatry and Biobehavioral Sciences, University of California Los Angeles
Assistant Professor-in-Residence, Human Genetics, University of California Los Angeles
Member, Bioinformatics GPB Home Area
We study the genetics of severe mental illness. By utilizing and developing computational approaches to leverage multi-level data, including psychiatric phenotypes, health records and molecular phenotypes, we aim to characterize and predict psychiatric disease trajectories. We have a special focus on studying genetic and environmental risk factors that contribute to the cause and course of illness in Latin American populations.
- Olde Loohuis LM, Mennigen E, Ori APS, Perkins D, Robinson E, Addington J, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Keshavan MS, Stone WS, Tsuang MT, Walker EF, Woods SW, Cannon TD, Gur RC, Gur RE, Bearden CE, Ophoff RA. Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD.. Translational psychiatry, 2021.
- Loohuis LM, Albersen M, de Jong S, Wu T, Luykx JJ, Jans JJM, Verhoeven-Duif NM, Ophoff RA. The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma.. Genes, 2018.