
M Carrie Miceli
Professor, MIMG, University of California Los Angeles
Department Address:
276B Biomedical Sciences Research Building
CAMPUS - 157005
CA
Laboratory Address:
257 Basic Sciences Research Building
Los Angeles, CA 90095
Lab Number:
206 6911
Work Address:
Department of Microbiology, Immunology, and Molecular Genetics
Los Angeles, CA 90095
Affiliations
Biography:
Dr. Miceli is a professor in the Department of Microbiology Immunology and Molecular genetics. She received her BA from UCSD in Biochemistry and Cell Biology, her PhD from Duke University studying the role of T cells in human kidney allograft rejection (Olja Finn, mentor) and did postdoctoral work at Stanford elucidating molecular mechanisms of CD4, CD8, Lck and TCR coreceptor functions (Jane Parne’s laboratory). In her own laboratory her group has identified mechanisms and modulators of TCR signal specificity and T cell function, with broad application to signal transduction in general. In 2007, with colleagues, r. Miceli founded the Center for Duchenne Muscular Dystrophy (CDMD), which formed and catalyzed new DMD team science approaches to translational research, drug discovery, and clinical trial development on campus and nationwide. Combining her expertise in these areas she is now focused on dystrophin replacement therapies and immune drivers of regeneration, fibrosis and muscle tissue tolerance.
Publications
- Miceli MC, Nelson SF. The case for eteplirsen: Paving the way for precision medicine.. Molecular genetics and metabolism, 2016.
- Miceli MC, Moran M, Chung CD, Patel VP, Low T, Zinnanti W. Co-stimulation and counter-stimulation: lipid raft clustering controls TCR signaling and functional outcomes.. Seminars in immunology, 2001.