Margot E. Quinlan*

Margot Elizabeth Quinlan

Professor, Chemistry and Biochemistry, University of California Los Angeles

UC Profile
Qlab website

Education and Training

University of PennsylvaniaPh.D.08/2002Cell and Molecular Biology
Reed CollegeB.A.09/1991Biology

Publications

  1. Bremer KV, Wu C, Patel AA, He KL, Grunfeld AM, Chanfreau GF, Quinlan ME. Formin tails act as a switch, inhibiting or enhancing processive actin elongation.. The Journal of biological chemistry, 2023.
  2. Valencia DA, Quinlan ME. Formins.. Current biology : CB, 2021.
  3. Bradley AO, Vizcarra CL, Bailey HM, Quinlan ME. Spire stimulates nucleation by Cappuccino and binds both ends of actin filaments.. Molecular biology of the cell, 2019.
  4. Kudryashova E, Heisler DB, Williams B, Harker AJ, Shafer K, Quinlan ME, Kovar DR, Vavylonis D, Kudryashov DS. Actin Cross-Linking Toxin Is a Universal Inhibitor of Tandem-Organized and Oligomeric G-Actin Binding Proteins.. Current biology : CB, 2018.
  5. Silkworth WT, Kunes KL, Nickel GC, Phillips ML, Quinlan ME, Vizcarra CL. The neuron-specific formin Delphilin nucleates nonmuscle actin but does not enhance elongation.. Molecular biology of the cell, 2017.
  6. Patel AA, Oztug Durer ZA, van Loon AP, Bremer KV, Quinlan ME. Drosophila and human FHOD family formin proteins nucleate actin filaments.. The Journal of biological chemistry, 2017.
  7. Vizcarra CL, Quinlan ME. Actin filament assembly by bacterial factors VopL/F: Which end is up?. The Journal of cell biology, 2017.
  8. Quinlan ME. Cytoplasmic Streaming in the Drosophila Oocyte.. Annual review of cell and developmental biology, 2016.
  9. Oztug Durer ZA, McGillivary RM, Kang H, Elam WA, Vizcarra CL, Hanein D, De La Cruz EM, Reisler E, Quinlan ME. Metavinculin Tunes the Flexibility and the Architecture of Vinculin-Induced Bundles of Actin Filaments.. Journal of molecular biology, 2015.
  10. Yoo H, Roth-Johnson EA, Bor B, Quinlan ME. Drosophila Cappuccino alleles provide insight into formin mechanism and role in oogenesis.. Molecular biology of the cell, 2015.
  11. Bor B, Bois JS, Quinlan ME. Regulation of the formin Cappuccino is critical for polarity of Drosophila oocytes.. Cytoskeleton (Hoboken, N.J.), 2015.
  12. Fattouh R, Kwon H, Czuczman MA, Copeland JW, Pelletier L, Quinlan ME, Muise AM, Higgins DE, Brumell JH. The diaphanous-related formins promote protrusion formation and cell-to-cell spread of Listeria monocytogenes.. The Journal of infectious diseases, 2014.
  13. Vizcarra CL, Bor B, Quinlan ME. The role of formin tails in actin nucleation, processive elongation, and filament bundling.. The Journal of biological chemistry, 2014.
  14. Rasson AS, Bois JS, Pham DSL, Yoo H, Quinlan ME. Filament assembly by Spire: key residues and concerted actin binding.. Journal of molecular biology, 2014.
  15. Roth-Johnson EA, Vizcarra CL, Bois JS, Quinlan ME. Interaction between microtubules and the Drosophila formin Cappuccino and its effect on actin assembly.. The Journal of biological chemistry, 2013.
  16. Quinlan ME. Direct interaction between two actin nucleators is required in Drosophila oogenesis.. Development (Cambridge, England), 2013.
  17. Bor B, Vizcarra CL, Phillips ML, Quinlan ME. Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains.. Molecular biology of the cell, 2012.
  18. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. Construction of flow chambers for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays.. Cold Spring Harbor protocols, 2012.
  19. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. The acquisition and analysis of polarized total internal reflection fluorescence microscopy (polTIRFM) data.. Cold Spring Harbor protocols, 2012.
  20. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. The polarized total internal reflection fluorescence microscopy (polTIRFM) processive motility assay for myosin V.. Cold Spring Harbor protocols, 2012.
  21. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. The polarized total internal reflection fluorescence microscopy (polTIRFM) twirling filament assay.. Cold Spring Harbor protocols, 2012.
  22. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. Fluorescent labeling of calmodulin with bifunctional rhodamine.. Cold Spring Harbor protocols, 2012.
  23. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. Fluorescent labeling of myosin V for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays.. Cold Spring Harbor protocols, 2012.
  24. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. Orientation and rotational motions of single molecules by polarized total internal reflection fluorescence microscopy (polTIRFM).. Cold Spring Harbor protocols, 2012.
  25. Beausang JF, Sun Y, Quinlan ME, Forkey JN, Goldman YE. Preparation of filamentous actin for polarized total internal reflection fluorescence microscopy (polTIRFM) motility assays.. Cold Spring Harbor protocols, 2012.
  26. Chen CK, Sawaya MR, Phillips ML, Reisler E, Quinlan ME. Multiple forms of Spire-actin complexes and their functional consequences.. The Journal of biological chemistry, 2012.
  27. Vizcarra CL, Kreutz B, Rodal AA, Toms AV, Lu J, Zheng W, Quinlan ME, Eck MJ. Structure and function of the interacting domains of Spire and Fmn-family formins.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
  28. Zuchero JB, Coutts AS, Quinlan ME, Thangue NB, Mullins RD. p53-cofactor JMY is a multifunctional actin nucleation factor.. Nature cell biology, 2009.
  29. Quinlan ME, Kerkhoff E. Actin nucleation: bacteria get in-Spired.. Nature cell biology, 2008.
  30. Quinlan ME, Hilgert S, Bedrossian A, Mullins RD, Kerkhoff E. Regulatory interactions between two actin nucleators, Spire and Cappuccino.. The Journal of cell biology, 2007.
  31. Rosenberg SA, Quinlan ME, Forkey JN, Goldman YE. Rotational motions of macro-molecules by single-molecule fluorescence microscopy.. Accounts of chemical research, 2005.
  32. Forkey JN, Quinlan ME, Goldman YE. Measurement of single macromolecule orientation by total internal reflection fluorescence polarization microscopy.. Biophysical journal, 2005.
  33. Quinlan ME, Forkey JN, Goldman YE. Orientation of the myosin light chain region by single molecule total internal reflection fluorescence polarization microscopy.. Biophysical journal, 2005.
  34. Quinlan ME, Heuser JE, Kerkhoff E, Mullins RD. Drosophila Spire is an actin nucleation factor.. Nature, 2005.
  35. Forkey JN, Quinlan ME, Shaw MA, Corrie JE, Goldman YE. Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization.. Nature, 2003.
  36. Quinlan ME, Forkey JN, Goldman YE. Kinesin-ADP: whole lotta shakin' goin' on.. Nature structural biology, 2001.
  37. Forkey JN, Quinlan ME, Goldman YE. Protein structural dynamics by single-molecule fluorescence polarization.. Progress in biophysics and molecular biology, 2000.