Mario C. Deng*

Mario C Deng

Professor-in-Residence, Medicine, University of California Los Angeles

310-825-3056

Publications

  1. Kosaraju R, Vandenbogaart E, Core E, Creaser J, Livingston N, Moore M, Kamath M, Deng M. Higher-risk SIPAT score predicts increased risk of long-term mortality in orthotopic heart transplant recipients.. International journal of cardiology, 2023.
  2. Deng MC. An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19.. Expert review of clinical immunology, 2023.
  3. Romero E, Tabak E, Fishbein G, Litovsky S, Tallaj J, Liem D, Bakir M, Khachatoorian Y, Piening B, Keating B, Deng M, Cadeiras M. Unsupervised mRNA-seq classification of heart transplant endomyocardial biopsies.. Clinical transplantation, 2023.
  4. Madill-Thomsen KS, Reeve J, Aliabadi-Zuckermann A, Cadeiras M, Crespo-Leiro MG, Depasquale EC, Deng M, Goekler J, Kim DH, Kobashigawa J, Macdonald P, Potena L, Shah K, Stehlik J, Zuckermann A, Halloran PF. Assessing the Relationship Between Molecular Rejection and Parenchymal Injury in Heart Transplant Biopsies.. Transplantation, 2022.
  5. Kamath M, Shekhtman G, Grogan T, Hickey MJ, Silacheva I, Shah KS, Shah KS, Hairapetian A, Gonzalez D, Godoy G, Reed EF, Elashoff D, Bondar G, Deng MC. Variability in Donor-Derived Cell-Free DNA Scores to Predict Mortality in Heart Transplant Recipients - A Proof-of-Concept Study.. Frontiers in immunology, 2022.
  6. Piening BD, Dowdell AK, Zhang M, Loza BL, Walls D, Gao H, Mohebnasab M, Li YR, Elftmann E, Wei E, Gandla D, Lad H, Chaib H, Sweitzer NK, Deng M, Pereira AC, Cadeiras M, Shaked A, Snyder MP, Keating BJ. Whole transcriptome profiling of prospective endomyocardial biopsies reveals prognostic and diagnostic signatures of cardiac allograft rejection.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022.
  7. Ahn R, Schaenman J, Qian Z, Pickering H, Groysberg V, Rossetti M, Llamas M, Hoffmann A, Gjertson D, Deng M, Bunnapradist S, Reed EF, CMV Systems Immunobiology Group. Acute and Chronic Changes in Gene Expression After CMV DNAemia in Kidney Transplant Recipients.. Frontiers in immunology, 2021.
  8. Pickering H, Sen S, Arakawa-Hoyt J, Ishiyama K, Sun Y, Parmar R, Ahn RS, Sunga G, Llamas M, Hoffmann A, Deng M, Bunnapradist S, Schaenman JM, Gjertson DW, Rossetti M, Lanier LL, Reed EF, CMV Systems Immunobiology Group. NK and CD8+ T cell phenotypes predict onset and control of CMV viremia after kidney transplant.. JCI insight, 2021.
  9. Halloran PF, Madill-Thomsen K, Aliabadi-Zuckermann AZ, Cadeiras M, Crespo-Leiro MG, Depasquale EC, Deng M, Gökler J, Kim DH, Kobashigawa J, Macdonald P, Potena L, Shah K, Stehlik J, Zuckermann A. Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021.
  10. Stein-Merlob AF, Hsu JJ, Colton B, Berg CJ, Ferreira A, Price MM, Wainberg Z, Baas AS, Deng MC, Parikh RV, Yang EH. Keeping immune checkpoint inhibitor myocarditis in check: advanced circulatory mechanical support as a bridge to recovery.. ESC heart failure, 2021.
  11. Reardon LC, Lin JP, VanArsdell GS, Kaldas FM, Lluri G, Tan W, Whalen KM, Cruz D, Nsair A, Deng MC, Moore MA, Laks H, Biniwale RM, Saab S, Baird A, Wilson JM, Lubin LN, Marijic J, Williams TM, Wray CL, Meltzer JS, Gudzenko V, Kratzert WB, Neelankavil J, Venick RS, Aboulhosn JA. Orthotopic Heart and Combined Heart Liver Transplantation: the Ultimate Treatment Option for Failing Fontan Physiology.. Current transplantation reports, 2021.
  12. Khachatoorian Y, Khachadourian V, Chang E, Sernas ER, Reed EF, Deng M, Piening BD, Pereira AC, Keating B, Cadeiras M. Noninvasive biomarkers for prediction and diagnosis of heart transplantation rejection.. Transplantation reviews (Orlando, Fla.), 2020.
  13. Deng MC. The evolution of patient-specific precision biomarkers to guide personalized heart-transplant care.. Expert review of precision medicine and drug development, 2020.
  14. Romero E, Chang E, Tabak E, Pinheiro D, Tallaj J, Litovsky S, Keating B, Deng M, Cadeiras M. Rejection-associated Mitochondrial Impairment After Heart Transplantation.. Transplantation direct, 2020.
  15. Hsu JJ, Al-Saffar F, Ardehali R, Baas AS, Carlson M, Cruz D, Deng M, Fan A, Fraschilla S, Gaynor P, Kamath M, Kubak BM, Schaenman J, Stimpson E, Vucicevic D, Ardehali A, Nsair A. Heart transplantation in the early phase of the COVID-19 pandemic: A single-center case series.. Clinical transplantation, 2020.
  16. Deng MC. Multi-dimensional COVID-19 short- and long-term outcome prediction algorithm.. Expert review of precision medicine and drug development, 2020.
  17. Butler CL, Hickey MJ, Jiang N, Zheng Y, Gjertson D, Zhang Q, Rao P, Fishbein GA, Cadeiras M, Deng MC, Banchs HL, Torre G, DeNofrio D, Eisen HJ, Kobashigawa J, Starling RC, Kfoury A, Van Bakel A, Ewald G, Balazs I, Baas AS, Cruz D, Ardehali R, Biniwale R, Kwon M, Ardehali A, Nsair A, Ray B, Reed EF. Discovery of non-HLA antibodies associated with cardiac allograft rejection and development and validation of a non-HLA antigen multiplex panel: From bench to bedside.. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020.
  18. Bondar G, Xu W, Elashoff D, Li X, Faure-Kumar E, Bao TM, Grogan T, Moose J, Deng MC. Comparing NGS and NanoString platforms in peripheral blood mononuclear cell transcriptome profiling for advanced heart failure biomarker development.. Journal of biological methods, 2020.
  19. Iyengar A, Wisniewski N, Kwon OJ, Cadeiras M, Deng M, Schaenman J, Korin Y, Shemin R, Reed E, Kwon M. Temporal expression of cytokines and B-cell phenotypes during mechanical circulatory support.. The Journal of thoracic and cardiovascular surgery, 2019.
  20. Parkes MD, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Halloran PF. An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019.
  21. Schaenman JM, Rossetti M, Sidwell T, Groysberg V, Sunga G, Liang E, Vangala S, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation.. Human immunology, 2018.
  22. Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.. G3 (Bethesda, Md.), 2018.
  23. Halloran PF, Reeve J, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Jouven X, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Parkes MD. Exploring the cardiac response to injury in heart transplant biopsies.. JCI insight, 2018.
  24. Zhang Q, Hickey M, Drogalis-Kim D, Zheng Y, Gjertson D, Cadeiras M, Khuu T, Baas AS, Depasquale EC, Halnon NJ, Perens G, Alejos J, Cruz D, Ali N, Shemin R, Kwon M, Fishbein MC, Ardehali A, Deng M, Reed EF. Understanding the Correlation Between DSA, Complement Activation, and Antibody-Mediated Rejection in Heart Transplant Recipients.. Transplantation, 2018.
  25. Reardon LC, DePasquale EC, Tarabay J, Cruz D, Laks H, Biniwale RM, Busuttil RW, Kaldas FM, Saab S, Venick RS, Lin JP, Nsair A, Deng MC, Ardehali A, Caderias M, Iygengar A, Aboulhosn JA. Heart and heart-liver transplantation in adults with failing Fontan physiology.. Clinical transplantation, 2018.
  26. Deng MC. A peripheral blood transcriptome biomarker test to diagnose functional recovery potential in advanced heart failure.. Biomarkers in medicine, 2018.
  27. Bakir M, Jackson NJ, Han SX, Bui A, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. Clinical phenomapping and outcomes after heart transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2018.
  28. Schaenman JM, Rossetti M, Korin Y, Sidwell T, Groysberg V, Liang E, Vangala S, Wisniewski N, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. T cell dysfunction and patient age are associated with poor outcomes after mechanical circulatory support device implantation.. Human immunology, 2018.
  29. Heinemann FG, Tolkach Y, Deng M, Schmidt D, Perner S, Kristiansen G, Müller SC, Ellinger J. Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma.. Clinical epigenetics, 2018.
  30. Vucicevic D, Honoris L, Raia F, Deng M. Current indications for transplantation: stratification of severe heart failure and shared decision-making.. Annals of cardiothoracic surgery, 2018.
  31. Doering LV, Chen B, Deng M, Mancini D, Kobashigawa J, Hickey K. Perceived control and health-related quality of life in heart transplant recipients.. European journal of cardiovascular nursing, 2017.
  32. Bondar G, Togashi R, Cadeiras M, Schaenman J, Cheng RK, Masukawa L, Hai J, Bao TM, Chu D, Chang E, Bakir M, Kupiec-Weglinski S, Groysberg V, Grogan T, Meltzer J, Kwon M, Rossetti M, Elashoff D, Reed E, Ping PP, Deng MC. Association between preoperative peripheral blood mononuclear cell gene expression profiles, early postoperative organ function recovery potential and long-term survival in advanced heart failure patients undergoing mechanical circulatory support.. PloS one, 2017.
  33. Wisniewski N, Bondar G, Rau C, Chittoor J, Chang E, Esmaeili A, Cadeiras M, Deng M. Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study.. BMC medical genomics, 2017.
  34. Tuzovic M, Yang EH, Baas AS, Depasquale EC, Deng MC, Cruz D, Vorobiof G. Cardiac Amyloidosis: Diagnosis and Treatment Strategies.. Current oncology reports, 2017.
  35. Vandenbogaart E, Doering L, Chen B, Saltzman A, Chaker T, Creaser JW, Rourke D, Cheng RW, Fonarow GC, Deng M. Evaluation of the SIPAT instrument to assess psychosocial risk in heart transplant candidates: A retrospective single center study.. Heart & lung : the journal of critical care, 2017.
  36. Moazeni S, Cadeiras M, Yang EH, Deng MC, Nguyen KL. Anthracycline induced cardiotoxicity: biomarkers and "Omics" technology in the era of patient specific care.. Clinical and translational medicine, 2017.
  37. Deng MC. The AlloMap™ genomic biomarker story: 10 years after.. Clinical transplantation, 2017.
  38. Raia F, Deng MC. Artificial heart pumps: bridging the gap between science, technology and personalized medicine by relational medicine.. Future cardiology, 2016.
  39. von Mässenhausen A, Sanders C, Thewes B, Deng M, Queisser A, Vogel W, Kristiansen G, Duensing S, Schröck A, Bootz F, Brossart P, Kirfel J, Heasley L, Brägelmann J, Perner S. MERTK as a novel therapeutic target in head and neck cancer.. Oncotarget, 2016.
  40. DePasquale EC, Cheng RK, Deng MC, Nsair A, McKenna WJ, Fonarow GC, Jacoby DL. Survival After Heart Transplantation in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy.. Journal of cardiac failure, 2016.
  41. Mukku RB, Fonarow GC, Watson KE, Ajijola OA, Depasquale EC, Nsair A, Baas AS, Deng MC, Yang EH. Heart Failure Therapies for End-Stage Chemotherapy-Induced Cardiomyopathy.. Journal of cardiac failure, 2016.
  42. Schrödter S, Braun M, Syring I, Klümper N, Deng M, Schmidt D, Perner S, Müller SC, Ellinger J. Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma.. Molecular cancer, 2016.
  43. Crespo-Leiro MG, Stypmann J, Schulz U, Zuckermann A, Mohacsi P, Bara C, Ross H, Parameshwar J, Zakliczynski M, Fiocchi R, Hoefer D, Colvin M, Deng MC, Leprince P, Elashoff B, Yee JP, Vanhaecke J. Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II.. European heart journal, 2016.
  44. Crespo-Leiro MG, Stypmann J, Schulz U, Zuckermann A, Mohacsi P, Bara C, Ross H, Parameshwar J, Zakliczynski M, Fiocchi R, Hoefer D, Deng M, Leprince P, Hiller D, Eubank L, Deljkich E, Yee JP, Vanhaecke J. Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients.. BMC cardiovascular disorders, 2015.
  45. Creaser JW, Rourke D, Vandenbogaart E, Chaker T, Nsair A, Cheng R, Fonarow G, Livingston N, Howell E, Huie N, Baas AS, Deng M, Hickey A, Shemin RJ, MacLellan WR. Outcomes of biventricular mechanical support patients discharged to home to await heart transplantation.. The Journal of cardiovascular nursing, 2015.
  46. Ardehali A, Esmailian F, Deng M, Soltesz E, Hsich E, Naka Y, Mancini D, Camacho M, Zucker M, Leprince P, Padera R, Kobashigawa J, PROCEED II trial investigators. Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial.. Lancet (London, England), 2015.
  47. Khush KK, Pham MX, Teuteberg JJ, Kfoury AG, Deng MC, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Hiller D, Yee J, Valantine HA. Gene expression profiling to study racial differences after heart transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2015.
  48. Khuu T, Cadeiras M, Wisniewski N, Reed EF, Deng MC. Reduced HLA Class II antibody response to proteasome inhibition in heart transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2015.
  49. Kwon MH, Zhang JQ, Schaenman JM, Cadeiras M, Gjertson DW, Krystal CA, Laks H, Ardehali A, Deng MC, Shemin RJ, Reed EF. Characterization of ventricular assist device-mediated sensitization in the bridge-to-heart-transplantation patient.. The Journal of thoracic and cardiovascular surgery, 2015.
  50. Raia F, Deng MC. Is relational medicine the key to providing truly personalized high-tech modern medicine?. Personalized medicine, 2015.
  51. Bondar G, Cadeiras M, Wisniewski N, Maque J, Chittoor J, Chang E, Bakir M, Starling C, Shahzad K, Ping P, Reed E, Deng M. Comparison of whole blood and peripheral blood mononuclear cell gene expression for evaluation of the perioperative inflammatory response in patients with advanced heart failure.. PloS one, 2014.
  52. Labarrere CA, Woods JR, Hardin JW, Jaeger BR, Zembala M, Deng MC, Kassab GS. Early inflammatory markers are independent predictors of cardiac allograft vasculopathy in heart-transplant recipients.. PloS one, 2014.
  53. Li F, Wei J, Valenzuela NM, Lai C, Zhang Q, Gjertson D, Fishbein MC, Kobashigawa JA, Deng M, Reed EF. Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2014.
  54. DiFranco M, Quiñonez M, Shieh P, Fonarow GC, Cruz D, Deng MC, Vergara JL, Middlekauff HR. Action potential-evoked calcium release is impaired in single skeletal muscle fibers from heart failure patients.. PloS one, 2014.
  55. Wang D, Liem DA, Lau E, Ng DC, Bleakley BJ, Cadeiras M, Deng MC, Lam MP, Ping P. Characterization of human plasma proteome dynamics using deuterium oxide.. Proteomics. Clinical applications, 2014.
  56. Sung EC, Brar LK, Chung E, Kubak B, Carlson M, Deng M, Friedlander AH. Dental treatment in the cardiothoracic intensive care unit for patients with ventricular assist devices awaiting heart transplant: a case series.. Oral surgery, oral medicine, oral pathology and oral radiology, 2014.
  57. X'avia Chan CY, Wang D, Cadeiras M, Deng MC, Ping P. S-nitrosylation of TRIM72 mends the broken heart: a molecular modifier-mediated cardioprotection.. Journal of molecular and cellular cardiology, 2014.
  58. Deng MC, Elashoff B, Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Shahzad K, Hiller D, Yee J, Valantine HA, IMAGE Study Group. Utility of gene expression profiling score variability to predict clinical events in heart transplant recipients.. Transplantation, 2014.
  59. Lam MP, Wang D, Lau E, Liem DA, Kim AK, Ng DC, Liang X, Bleakley BJ, Liu C, Tabaraki JD, Cadeiras M, Wang Y, Deng MC, Ping P. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation.. The Journal of clinical investigation, 2014.
  60. Liem DA, Nsair A, Setty SP, Cadeiras M, Wang D, Maclellan R, Lotz C, Lin AJ, Tabaraki J, Li H, Ge J, Odeberg J, Ponten F, Larson E, Mulder J, Lundberg E, Weiss JN, Uhlen M, Ping P, Deng MC. Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support.. Circulation. Heart failure, 2014.
  61. Adigopula S, Vivo RP, DePasquale EC, Nsair A, Deng MC. Management of ACCF/AHA Stage C heart failure.. Cardiology clinics, 2014.
  62. Nsair A, Liem DA, Cadeiras M, Cheng RK, Allareddy M, Kwon M, Shemin R, Deng MC. Molecular basis of recovering on mechanical circulatory support.. Heart failure clinics, 2014.
  63. Menon R, Deng M, Rüenauver K, Queisser A, Peifer M, Pfeifer M, Offermann A, Boehm D, Vogel W, Scheble V, Fend F, Kristiansen G, Wernert N, Oberbeckmann N, Biskup S, Rubin MA, Adler D, Perner S. Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer.. The Journal of pathology, 2013.
  64. Deng M, Cadeiras M, Reed EF. The multidimensional perspective of cardiac allograft rejection.. Current opinion in organ transplantation, 2013.
  65. Wang D, Fang C, Zong NC, Liem DA, Cadeiras M, Scruggs SB, Yu H, Kim AK, Yang P, Deng M, Lu H, Ping P. Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human.. Molecular & cellular proteomics : MCP, 2013.
  66. Cheng RK, DePasquale EC, Deng MC, Nsair A, Horwich TB. Obesity in heart failure: impact on survival and treatment modalities.. Expert review of cardiovascular therapy, 2013.
  67. Chan CX, Khan AA, Choi JH, Ng CD, Cadeiras M, Deng M, Ping P. Technology platform development for targeted plasma metabolites in human heart failure.. Clinical proteomics, 2013.
  68. Westaby S, Deng M. Continuous flow blood pumps: the new gold standard for advanced heart failure?. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2013.
  69. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation.. Circulation. Heart failure, 2013.
  70. Feldman D, Pamboukian SV, Teuteberg JJ, Birks E, Lietz K, Moore SA, Morgan JA, Arabia F, Bauman ME, Buchholz HW, Deng M, Dickstein ML, El-Banayosy A, Elliot T, Goldstein DJ, Grady KL, Jones K, Hryniewicz K, John R, Kaan A, Kusne S, Loebe M, Massicotte MP, Moazami N, Mohacsi P, Mooney M, Nelson T, Pagani F, Perry W, Potapov EV, Eduardo Rame J, Russell SD, Sorensen EN, Sun B, Strueber M, Mangi AA, Petty MG, Rogers J, International Society for Heart and Lung Transplantation. The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2013.
  71. Crespo-Leiro MG, Zuckermann A, Bara C, Mohacsi P, Schulz U, Boyle A, Ross HJ, Parameshwar J, Zakliczynski M, Fiocchi R, Stypmann J, Hoefer D, Lehmkuhl H, Deng MC, Leprince P, Berry G, Marboe CC, Stewart S, Tazelaar HD, Baron HM, Coleman IC, Vanhaecke J. Concordance among pathologists in the second Cardiac Allograft Rejection Gene Expression Observational Study (CARGO II).. Transplantation, 2012.
  72. Khuu T, Hickey A, Deng MC. Pomegranate-containing products and tacrolimus: a potential interaction.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012.
  73. Kwon MH, Wong SY, Ardehali A, Laks H, Zhang ZK, Deng MC, Shemin RJ. Primary graft dysfunction does not lead to increased cardiac allograft vasculopathy in surviving patients.. The Journal of thoracic and cardiovascular surgery, 2012.
  74. Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases.. Circulation research, 2012.
  75. Cheng RK, Deng MC, Tseng CH, Shemin RJ, Kubak BM, MacLellan WR. Risk stratification in patients with advanced heart failure requiring biventricular assist device support as a bridge to cardiac transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012.
  76. Deng MC, Ardehali A, Shemin R, Hickey A, MacLellan WR, Fonarow G. Relative roles of heart transplantation and long-term mechanical circulatory support in contemporary management of advanced heart failure - a critical appraisal 10 years after REMATCH.. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011.
  77. Festa JR, Jia X, Cheung K, Marchidann A, Schmidt M, Shapiro PA, Mancini DM, Naka Y, Deng M, Lantz ER, Marshall RS, Lazar RM. Association of low ejection fraction with impaired verbal memory in older patients with heart failure.. Archives of neurology, 2011.
  78. Weidner G, Zahn D, Mendell NR, Smits JM, Deng MC, Zittermann A, Spaderna H, Waiting for a New Heart Study Group. Patients' sex and emotional support as predictors of death and clinical deterioration in the waiting for a new heart study: results from the 1-year follow-up.. Progress in transplantation (Aliso Viejo, Calif.), 2011.
  79. Sims DB, Uriel N, González-Costello J, Deng MC, Restaino SW, Farr MA, Takayama H, Mancini DM, Naka Y, Jorde UP. Human immunodeficiency virus infection and left ventricular assist devices: a case series.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2011.
  80. Cadeiras M, von Bayern M, Sinha A, Shahzad K, Latif F, Lim WK, Grenett H, Tabak E, Klingler T, Califano A, Deng MC. Drawing networks of rejection - a systems biological approach to the identification of candidate genes in heart transplantation.. Journal of cellular and molecular medicine, 2011.
  81. Shahzad K, Cadeiras M, Memon S, Zeeberg B, Klingler T, Sinha A, Tabak EG, Unniachan S, Deng MC. Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy.. Journal of transplantation, 2010.
  82. Zahn D, Weidner G, Beyersmann J, Smits JM, Deng MC, Kaczmarek I, Meyer S, Reichenspurner H, Mehlhorn U, Wagner FM, Spaderna H. Composite risk scores and depression as predictors of competing waiting-list outcomes: the Waiting for a New Heart Study.. Transplant international : official journal of the European Society for Organ Transplantation, 2010.
  83. Ho EK, Vlad G, Vasilescu ER, de la Torre L, Colovai AI, Burke E, Deng M, Schwartz J, Marboe C, Mancini D, Opelz G, Suciu-Foca N. Pre- and posttransplantation allosensitization in heart allograft recipients: major impact of de novo alloantibody production on allograft survival.. Human immunology, 2010.
  84. Shahzad K, Aziz QA, Leva JP, Cadeiras M, Ho EK, Vlad G, Vasilescu ER, Latif F, Sinha A, Burke E, Addonizio LJ, Restaino SW, Marboe CC, Suciu-Foca N, Naka Y, Mancini D, Deng MC. New-onset graft dysfunction after heart transplantation--incidence and mechanism-related outcomes.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010.
  85. Deng MC, Alexander G, Wolters H, Shahzad K, Cadeiras M, Hicks A, Rowe T, Klingler TM, Eisen HJ. Low variability of intraindividual longitudinal leukocyte gene expression profiling cardiac allograft rejection scores.. Transplantation, 2010.
  86. Shahzad K, Cadeiras M, Arai K, Abramov D, Burke E, Deng MC. Unexplained Graft Dysfunction after Heart Transplantation-Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report.. Cardiology research and practice, 2010.
  87. Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Deng MC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Elashoff B, Baron H, Yee J, Valantine HA, IMAGE Study Group. Gene-expression profiling for rejection surveillance after cardiac transplantation.. The New England journal of medicine, 2010.
  88. Shahzad K, He J, Li Q, Aziz QA, Deng MC. Relationship between prolonged QTc interval, cardiac allograft dysfunction and elevated molecular gene expression profiling test score after heart transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010.
  89. Sinha A, Shahzad K, Latif F, Cadeiras M, Von Bayern MP, Oz S, Naka Y, Deng MC. Peripheral blood mononuclear cell transcriptome profiles suggest T-cell immunosuppression after uncomplicated mechanical circulatory support device surgery.. Human immunology, 2009.
  90. Cadeiras M, Shahzad K, John MM, Gruber D, Bayern Mv, Auerbach S, Sinha A, Latif F, Unniachan S, Memon S, Mital S, Restaino S, Marboe CC, Addonizio LJ, Deng MC. Relationship between a validated molecular cardiac transplant rejection classifier and routine organ function parameters.. Clinical transplantation, 2009.
  91. Uriel N, Jorde UP, Cotarlan V, Colombo PC, Farr M, Restaino SW, Lietz K, Naka Y, Deng MC, Mancini D. Heart transplantation in human immunodeficiency virus-positive patients.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009.
  92. Arrecubieta C, Toba FA, von Bayern M, Akashi H, Deng MC, Naka Y, Lowy FD. SdrF, a Staphylococcus epidermidis surface protein, contributes to the initiation of ventricular assist device driveline-related infections.. PLoS pathogens, 2009.
  93. Lietz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers JG, Miller LW, Deng M, Naka Y, Mancini D. Impact of center volume on outcomes of left ventricular assist device implantation as destination therapy: analysis of the Thoratec HeartMate Registry, 1998 to 2005.. Circulation. Heart failure, 2009.
  94. Mignatti A, Sims DB, Colombo PC, Garcia LI, Bijou R, Deng MC, Jorde UP. Resting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy.. Cardiovascular therapeutics, 2009.
  95. Cooper LT, Hare JM, Tazelaar HD, Edwards WD, Starling RC, Deng MC, Menon S, Mullen GM, Jaski B, Bailey KR, Cunningham MW, Dec GW, Giant Cell Myocarditis Treatment Trial Investigators. Usefulness of immunosuppression for giant cell myocarditis.. The American journal of cardiology, 2008.
  96. Arrecubieta C, Matsunaga I, Asai T, Naka Y, Deng MC, Lowy FD. Vaccination with clumping factor A and fibronectin binding protein A to prevent Staphylococcus aureus infection of an aortic patch in mice.. The Journal of infectious diseases, 2008.
  97. Cadeiras M, Bayern M, Burke E, Dedrick R, Gangadin A, Latif F, Latif F, Shahzad K, Shazad K, Sinha A, Tabak EG, Marboe CC, Califano AC, Deng MC. Gene expression profiles of patients with antibody-mediated rejection after cardiac transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008.
  98. Latif F, Cadeiras M, von Bayern MP, Shahzad K, Sinha A, Deng MC. Challenges of long-term mechanical circulatory support therapy.. Expert review of medical devices, 2008.
  99. von Bayern MP, Arrecubieta C, Oz S, Akashi H, Cedeiras M, Naka Y, Deng MC, Lowy FD. Development of a murine ventricular assist device transcutaneous drive-line model.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008.
  100. George I, Colley P, Russo MJ, Martens TP, Burke E, Oz MC, Deng MC, Mancini DM, Naka Y. Association of device surface and biomaterials with immunologic sensitization after mechanical support.. The Journal of thoracic and cardiovascular surgery, 2008.
  101. Stewart AS, Russo MJ, Martens TP, Naseem TM, Deng MC, Wang R, Argenziano M, Oz M, Naka Y. Longer duration of continuous-flow ventricular assist device support predicts greater hemodynamic compromise after return of pulsatility.. The Journal of thoracic and cardiovascular surgery, 2008.
  102. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klingler TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ, CARGO Investigators. Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008.
  103. Bernstein D, Williams GE, Eisen H, Mital S, Wohlgemuth JG, Klingler TM, Fang KC, Deng MC, Kobashigawa J. Gene expression profiling distinguishes a molecular signature for grade 1B mild acute cellular rejection in cardiac allograft recipients.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2007.
  104. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klingler TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ, CARGO Investigators. Transcriptional signals of T-cell and corticosteroid-sensitive genes are associated with future acute cellular rejection in cardiac allografts.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2007.
  105. Cadeiras M, von Bayern M, Deng MC. Managing drugs and devices in patients with permanent ventricular assist devices.. Current treatment options in cardiovascular medicine, 2007.
  106. Pham MX, Deng MC, Kfoury AG, Teuteberg JJ, Starling RC, Valantine H. Molecular testing for long-term rejection surveillance in heart transplant recipients: design of the Invasive Monitoring Attenuation Through Gene Expression (IMAGE) trial.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2007.
  107. Cadeiras M, von Bayern MP, Deng MC. Cardiac transplantation: any role left?. Heart failure clinics, 2007.
  108. von Bayern MP, Cadeiras M, Deng MC. Destination therapy: does progress depend on left ventricular assist device development?. Heart failure clinics, 2007.
  109. Li J, Cadeiras M, Prinz von Bayern M, Zhang L, Colovai AI, Dedrick R, Jaffe EA, Suciu-Foca N, Deng MC. G6b-B cell surface inhibitory receptor expression is highly restricted to CD4+ T-cells and induced by interleukin-4-activated STAT6 pathway.. Human immunology, 2007.
  110. Asai T, Lee MH, Arrecubieta C, von Bayern MP, Cespedes CA, Baron HM, Cadeiras M, Sakaguchi T, Marboe CC, Naka Y, Deng MC, Lowy FD. Cellular coating of the left ventricular assist device textured polyurethane membrane reduces adhesion of Staphylococcus aureus.. The Journal of thoracic and cardiovascular surgery, 2007.
  111. Maurer MS, Raina A, Hesdorffer C, Bijou R, Colombo P, Deng M, Drusin R, Haythe J, Horn E, Lee SH, Marboe C, Naka Y, Schulman L, Scully B, Shapiro P, Prager K, Radhakrishnan J, Restaino S, Mancini D. Cardiac transplantation using extended-donor criteria organs for systemic amyloidosis complicated by heart failure.. Transplantation, 2007.
  112. Starling RC, Pham M, Valantine H, Miller L, Eisen H, Rodriguez ER, Taylor DO, Yamani MH, Kobashigawa J, McCurry K, Marboe C, Mehra MR, Zuckerman A, Deng MC, Working Group on Molecular Testing in Cardiac Transplantation. Molecular testing in the management of cardiac transplant recipients: initial clinical experience.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2006.
  113. Gronda E, Bourge RC, Costanzo MR, Deng M, Mancini D, Martinelli L, Torre-Amione G, O'Hara ML, Chambers S. Heart rhythm considerations in heart transplant candidates and considerations for ventricular assist devices: International Society for Heart and Lung Transplantation guidelines for the care of cardiac transplant candidates--2006.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2006.
  114. von Scheidt W, Costard-Jaeckle A, Stempfle HU, Deng MC, Schwaab B, Haaff B, Naegele H, Mohacsi P, Trautnitz M, PROPHET Study Group. Prostaglandin E1 testing in heart failure-associated pulmonary hypertension enables transplantation: the PROPHET study.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2006.
  115. Butler J, Geisberg C, Howser R, Portner PM, Rogers JG, Deng MC, Pierson RN. Relationship between renal function and left ventricular assist device use.. The Annals of thoracic surgery, 2006.
  116. Arrecubieta C, Asai T, Bayern M, Loughman A, Fitzgerald JR, Shelton CE, Baron HM, Dang NC, Deng MC, Naka Y, Foster TJ, Lowy FD. The role of Staphylococcus aureus adhesins in the pathogenesis of ventricular assist device-related infections.. The Journal of infectious diseases, 2006.
  117. Deng MC, Edwards LB, Hertz MI, Rowe AW, Keck BM, Kormos R, Naftel DC, Kirklin JK, Taylor DO, International Society for Heart and Lung Transplantation. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: third annual report--2005.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005.
  118. Asai T, Baron HM, von Bayern MP, Sakaguchi T, Arrecubieta C, Cespedes CA, Lee MH, Lowy FD, Marboe CC, Deng MC, Naka Y. A mouse aortic patch model for mechanical circulatory support.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005.
  119. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Deng MC, Keck BM, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult heart transplant report--2005.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005.
  120. Hertz MI, Boucek MM, Deng MC, Edwards LB, Keck BM, Kirklin JK, Naftel DC, Rowe AW, Taylor DO, Trulock EP. Scientific Registry of the International Society for Heart and Lung Transplantation: introduction to the 2005 annual reports.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005.
  121. Marboe CC, Billingham M, Eisen H, Deng MC, Baron H, Mehra M, Hunt S, Wohlgemuth J, Mahmood I, Prentice J, Berry G. Nodular endocardial infiltrates (Quilty lesions) cause significant variability in diagnosis of ISHLT Grade 2 and 3A rejection in cardiac allograft recipients.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005.
  122. Evans RW, Williams GE, Baron HM, Deng MC, Eisen HJ, Hunt SA, Khan MM, Kobashigawa JA, Marton EN, Mehra MR, Mital SR. The economic implications of noninvasive molecular testing for cardiac allograft rejection.. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005.
  123. Deng MC. The challenges of generating evidence to guide mechanical circulatory support-based management of advanced heart failure.. European heart journal, 2005.
  124. Deng MC, Edwards LB, Hertz MI, Rowe AW, Keck BM, Kormos R, Naftel DC, Kirklin JK. Mechanical Circulatory Support Device Database of the International Society for Heart and Lung Transplantation: second annual report--2004.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004.
  125. Mehra MR, Benza R, Deng MC, Russell S, Webber S. Surrogate markers for late cardiac allograft survival.. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2004.
  126. Deng MC. Heart transplantation: the increasing challenges of evidence-based decision-making.. Journal of the American College of Cardiology, 2004.
  127. Mussivand T, Carrier M, Chiu RC, Davies RA, Delgado DH, Deng MC, Haddad H, Hendry PJ, Keon WJ, Koshal A, Masters RG, Mesana T, Rao V. Under-utilization of mechanical circulatory support in Canada: why and what can be done?. Artificial organs, 2004.
  128. Kirchhoff WCh, Gradaus R, Stypmann J, Deng MC, Tian TD, Scheld HH, Breithardt G, Brisse B. Vasoactive peptides during long-term follow-up of patients after cardiac transplantation.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004.
  129. Deng MC. Orthotopic heart transplantation: highlights and limitations.. The Surgical clinics of North America, 2004.
  130. Klotz S, Deng MC, Stypmann J, Roetker J, Wilhelm MJ, Hammel D, Scheld HH, Schmid C. Left ventricular pressure and volume unloading during pulsatile versus nonpulsatile left ventricular assist device support.. The Annals of thoracic surgery, 2004.
  131. van den Hout WB, Smits JM, Deng MC, Hummel M, Schoendube F, Scheld HH, Persijn GG, Laufer G, Comparative Outcome and Clinical Profiles in Transplantation study group, Eurotransplant heart transplant programs. The heart-allocation simulation model: a tool for comparison of transplantation allocation policies.. Transplantation, 2003.
  132. Bisleri G, Morgan JA, Deng MC, Mancini DM, Oz MC. Should HIV-positive recipients undergo heart transplantation?. The Journal of thoracic and cardiovascular surgery, 2003.
  133. Plenz GA, Eschert H, Deng MC. What are appropriate controls for cardiac interleukin-6 expression in heart failure?. Circulation, 2003.
  134. Smits JM, Deng MC, Hummel M, De Meester J, Schoendube F, Scheld HH, Persijn GG, Laufer G, Van Houwelingen HC, Comparative Outcome and Clinical Profiles in Transplantation (COCPIT) Study Group. A prognostic model for predicting waiting-list mortality for a total national cohort of adult heart-transplant candidates.. Transplantation, 2003.
  135. Klotz S, Deng MC, Hanafy D, Schmid C, Stypmann J, Schmidt C, Hammel D, Scheld HH. Reversible pulmonary hypertension in heart transplant candidates--pretransplant evaluation and outcome after orthotopic heart transplantation.. European journal of heart failure, 2003.
  136. Deng MC, Edwards LB, Hertz MI, Rowe AW, Kormos RL. Mechanical Circulatory Support device database of the International Society for Heart and Lung Transplantation: first annual report--2003.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003.
  137. Hertz MI, Mohacsi PJ, Taylor DO, Trulock EP, Boucek MM, Deng MC, Keck BM, Edwards LB, Rowe AW. The registry of the International Society for Heart and Lung Transplantation: introduction to the Twentieth Annual Reports--2003.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003.
  138. Deng MC. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation.. Current opinion in cardiology, 2003.
  139. Itescu S, Schuster M, Burke E, Ankersmit J, Kocher A, Deng M, John R, Lietz K. Immunobiologic consequences of assist devices.. Cardiology clinics, 2003.
  140. Deng MC, Smits JM, Young JB. Proposition: the benefit of cardiac transplantation in stable outpatients with heart failure should be tested in a randomized trial.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003.
  141. Plenz GA, Deng MC, Robenek H, Völker W. Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis.. Atherosclerosis, 2003.
  142. Feng S, Buell JF, Cherikh WS, Deng MC, Hanto DW, Kauffman HM, Leichtman AB, Lorber MI, Maters RG, McBride MA, Metzger RA, Nolte FS, O'Connor KJ, Roth D, Terrault NA, Henry ML. Organ donors with positive viral serology or malignancy: risk of disease transmission by transplantation.. Transplantation, 2002.
  143. Hertz MI, Mohacsi PJ, Boucek MM, Taylor DO, Trulock EP, Deng MC, Rowe AW. The Registry of the International Society for Heart and Lung Transplantation: past, present and future.. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2002.
  144. Grabellus F, Schmid C, Levkau B, Breukelmann D, Halloran PF, August C, Takeda N, Takeda A, Wilhelm M, Deng MC, Baba HA. Reduction of hypoxia-inducible heme oxygenase-1 in the myocardium after left ventricular mechanical support.. The Journal of pathology, 2002.
  145. Plenz G, Eschert H, Erren M, Wichter T, Böhm M, Flesch M, Scheld HH, Deng MC. The interleukin-6/interleukin-6-receptor system is activated in donor hearts.. Journal of the American College of Cardiology, 2002.
  146. Deng MC. Cardiac transplantation.. Heart (British Cardiac Society), 2002.
  147. Deng MC, Naka Y. Mechanical circulatory support devices--state of the art.. Heart failure monitor, 2002.
  148. Grabellus F, Levkau B, Sokoll A, Welp H, Schmid C, Deng MC, Takeda A, Breithardt G, Baba HA. Reversible activation of nuclear factor-kappaB in human end-stage heart failure after left ventricular mechanical support.. Cardiovascular research, 2002.