Matteo Pellegrini

Matteo Pellegrini

Professor, Molecular, Cell and Developmental Biology, University of California Los Angeles

Professor, Human Genetics, University of California Los Angeles

Professor, CA NanoSystems, University of California Los Angeles

Professor, Medicine, University of California Los Angeles


Laboratory Address:
3000 Terasaki Life Sciences Building

Lab Number:

Mailing Address:
UCLA Mol, Cell & Dvlmt Bio
BOX 951606
621 Charles E. Young Dr.
Los Angeles, CA 90095

Fax Number:
(310) 206-3987

Work Address:
3000C TSLB


Member, Bioinformatics GPB Home Area, California NanoSystems Institute, Cell & Developmental Biology GPB Home Area, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, Genetics & Genomics GPB Home Area, JCCC Gene Regulation Program Area, Medical Informatics GPB Home Area

Research Interests

Our lab is interested in the development of computational approaches to interpret genomic data. These methodologies allow us to develop large-scale models of transcriptional and epigenetic regulation as well as signal transduction. Our approach is to build models that integrate varied data that sheds light on these phenomena. This data is produced using the latest generation of high throughput sequencers, tiling and expression arrays along with mass spectrometry. Our research focuses on the development of both low and high-level analyses. For instance we are developing suites of tools for the analysis of high throughput sequencing data, as well as tools that combine multiple data types to infer transcriptional regulatory mechanisms.


Matteo Pellegrini is a biophysicist who has served on the UCLA Life Sciences Division faculty since he joined the Department of Molecular, Cell and Developmental Biology in 2005. Dr. Pellegrini earned his B.A. in Physics at Columbia University and his Ph.D. in Physics at Stanford. He was a postdoctoral fellow at UCLA, where he worked on computational biology. Following his postdoctoral studies Dr. Pellegrini co-founded a start-up company and later worked for the pharmaceutical company Merck before returning to UCLA. His laboratory research centers on the development of novel computational approaches to reverse engineer biomolecular networks. Professor Pellegrini is also a member of the California NanoSystems Institute (CNSI).