Professor of Clinical , Radiation Oncology, University of California Los Angeles
200 UCLA Medical Plaza, Suite B265
UCLA School of Medicine
Department of Radiation Oncology
Los Angeles, CA 90095
Dr. Agazaryan is a Professor of Radiation Oncology, Professor of the Physics and Biology in Medicine, and the Chief of Clinical Medical Physics at the UCLA School of Medicine. His appointment in the Department of Radiation Oncology involves research, teaching and clinical practice. Dr. Agazaryan is a Quality Officer of the UCLA Health’s Faculty Practice Group (FPG) and the UCLA Department of Radiation Oncology. Dr. Agazaryan has been elected a Fellow of the American Association of Physicists (FAAPM). The FAAPM election honors members who have distinguished themselves by their contributions in research, education and leadership.
Dr. Agazaryan is currently the lead professor of the UCLA Physics of Radiation Therapy Graduate Course (PB MED 203) and the Applications of Medical Physics to Clinical Problems: Radiation Therapy Clinical Rotation (PB MED 202C). Dr. Agazaryan is also engaged in mentoring medical physics graduate students, residents and junior faculty.
Dr. Agazaryan’s research and clinical interests include stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), with an emphasis on clinical implementation of translational research, clinical trials, small field dosimetry and image-guided radiotherapy (IGRT). He is an investigator of five clinical trials involving the use of Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiotherapy (SBRT). Dr. Agazaryan has made numerous international and national presentations, published over 40 peer-reviewed papers, over 120 abstracts, book editorial, booklet and several book chapters. Dr. Agazaryan is a Diplomate of The American Board of Radiology (DABR) – board certified in Therapeutic Radiologic Physics. He is also California State licensed to conduct therapy machine calibrations and radiation protection surveys.
- Wu TC, Xiang M, Nickols NG, Tenn S, Agazaryan N, Hegde JV, Steinberg ML, Cao M, Kishan AU. Prostate-Centric Versus Bony-Centric Registration in the Definitive Treatment of Node-Positive Prostate Cancer with Simultaneous Integrated Boost: A Dosimetric Comparison.. Advances in radiation oncology, 2022.
- Kienzler JC, Tenn S, Chivukula S, Chu FI, Sparks HD, Agazaryan N, Kim W, Salles A, Selch M, Gorgulho A, Kaprealian T, Pouratian N. Linear accelerator-based radiosurgery for trigeminal neuralgia: comparative outcomes of frame-based and mask-based techniques.. Journal of neurosurgery, 2021.
- Agazaryan N, Tenn S, Lee C, Steinberg M, Hegde J, Chin R, Pouratian N, Yang I, Kim W, Kaprealian T. Simultaneous radiosurgery for multiple brain metastases: technical overview of the UCLA experience.. Radiation oncology (London, England), 2021.
- Meeks SL, Mercado CE, Popple RA, Agazaryan N, Kaprealian T, Fiveash JB, Tenn S. Practical Considerations for Single Isocenter LINAC Radiosurgery of Multiple Brain Metastases.. Practical radiation oncology, 2021.
- Yoon SM, Luterstein E, Chu FI, Cao M, Lamb J, Agazaryan N, Low D, Raldow A, Steinberg ML, Lee P. Clinical outcomes of stereotactic magnetic resonance image-guided adaptive radiotherapy for primary and metastatic tumors in the abdomen and pelvis.. Cancer medicine, 2021.
- Ma TM, Lamb JM, Casado M, Wang X, Basehart TV, Yang Y, Low D, Sheng K, Agazaryan N, Nickols NG, Cao M, Steinberg ML, Kishan AU. Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial.. BMC cancer, 2021.
- Agazaryan N, Tenn S, Pouratian N, Kaprealian T. Intra-Fraction Motion Management for Radiosurgical Treatments of Trigeminal Neuralgia: Clinical Experience, Imaging Frequency, and Motion Analysis.. Cureus, 2021.
- Savjani RR, Salamon N, Deng J, Ma M, Tenn S, Agazaryan N, Hegde J, Kaprealian T. A Framework for Sharing Radiation Dose Distribution Maps in the Electronic Medical Record for Improving Multidisciplinary Patient Management.. Radiology. Imaging cancer, 2021.
- Chow PE, Chu FI, Agazaryan N, Cao M, Tyran M, Yang Y, Low D, Raldow A, Lee P, Steinberg M, Lamb JM. Dosimetric Quality of Online Adapted Pancreatic Cancer Treatment Plans on an MRI-Guided Radiation Therapy System.. Advances in radiation oncology, 2021.
- Levin-Epstein RG, Jiang NY, Wang X, Upadhyaya SK, Collins SP, Suy S, Aghdam N, Mantz C, Katz AJ, Miszczyk L, Napieralska A, Namysl-Kaletka A, Prionas N, Bagshaw H, Buyyounouski MK, Cao M, Agazaryan N, Dang A, Yuan Y, Kupelian PA, Zaorsky NG, Spratt DE, Mohamad O, Feng FY, Mahal BA, Boutros PC, Kishan AU, Juarez J, Shabsovich D, Jiang T, Kahlon S, Patel A, Patel J, Nickols NG, Steinberg ML, Fuller DB, Kishan AU. Dose-response with stereotactic body radiotherapy for prostate cancer: A multi-institutional analysis of prostate-specific antigen kinetics and biochemical control.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020.
- Kundu P, Jung OS, Valle LF, Edmondson AC, Agazaryan N, Hegde J, Steinberg M, Raldow A. Missing the Near Miss: Recognizing Valuable Learning Opportunities in Radiation Oncology.. Practical radiation oncology, 2020.
- Jung OS, Kundu P, Edmondson AC, Hegde J, Agazaryan N, Steinberg M, Raldow A. Resilience vs. Vulnerability: Psychological Safety and Reporting of Near Misses with Varying Proximity to Harm in Radiation Oncology.. Joint Commission journal on quality and patient safety, 2020.
- Parikh NR, Kundu P, Levin-Epstein R, Chang EM, Agazaryan N, Hegde JV, Steinberg ML, Tenn SE, Kaprealian TB. Time-Driven Activity-Based Costing Comparison of Stereotactic Radiosurgery to Multiple Brain Lesions Using Single-Isocenter Versus Multiple-Isocenter Technique.. International journal of radiation oncology, biology, physics, 2020.
- Parikh NR, Lee PP, Raman SS, Cao M, Lamb J, Tyran M, Chin W, Gilchrist T, Agazaryan N, Mittauer K, Steinberg ML, Raldow AC. Time-Driven Activity-Based Costing Comparison of CT-Guided Versus MR-Guided SBRT.. JCO oncology practice, 2020.
- Agazaryan N, Chow P, Lamb J, Cao M, Raldow A, Beron P, Hegde J, Steinberg M. The Timeliness Initiative: Continuous Process Improvement for Prompt Initiation of Radiation Therapy Treatment.. Advances in radiation oncology, 2020.
- Attiah M, Sandler K, Medina R, Gaonkar B, McArthur D, Farha G, Selch M, De Salles A, Tenn S, Agazaryan N, Lee P, Steinberg M, Lu D, Macyszyn L, Kaprealian T. Comparison of Clinical Outcomes Stratified by Target Delineation for Patients Undergoing Stereotactic Body Radiotherapy for Spinal Metastases.. World neurosurgery, 2019.
- Gorgulho A, Agazaryan N, Selch M, Santos BFO, De Salles A. Immediate Pain Relief Elicited After Radiosurgery for Classical and Symptomatic Trigeminal Neuralgia.. Cureus, 2019.
- O'Connell D, Thomas DH, Lewis JH, Hasse K, Santhanam A, Lamb JM, Cao M, Tenn S, Agazaryan N, Lee PP, Low DA. Safety-oriented design of in-house software for new techniques: A case study using a model-based 4DCT protocol.. Medical physics, 2019.
- Dang A, Kupelian PA, Cao M, Agazaryan N, Kishan AU. Image-guided radiotherapy for prostate cancer.. Translational andrology and urology, 2018.
- Sandler KA, Abtin F, Suh R, Cook RR, Felix C, Lee JM, Garon EB, Wu J, Luterstein EM, Agazaryan N, Tenn SE, Lee C, Steinberg ML, Lee P. A Prospective Phase 2 Study Evaluating Safety and Efficacy of Combining Stereotactic Body Radiation Therapy With Heat-based Ablation for Centrally Located Lung Tumors.. International journal of radiation oncology, biology, physics, 2018.
- Thomas DH, Santhanam A, Kishan AU, Cao M, Lamb J, Min Y, O'Connell D, Yang Y, Agazaryan N, Lee P, Low D. Initial clinical observations of intra- and interfractional motion variation in MR-guided lung SBRT.. The British journal of radiology, 2018.
- Lamb J, Cao M, Kishan A, Agazaryan N, Thomas DH, Shaverdian N, Yang Y, Ray S, Low DA, Raldow A, Steinberg ML, Lee P. Online Adaptive Radiation Therapy: Implementation of a New Process of Care.. Cureus, 2017.
- Lamb JM, Ginn JS, O'Connell DP, Agazaryan N, Cao M, Thomas DH, Yang Y, Lazea M, Lee P, Low DA. Dosimetric validation of a magnetic resonance image gated radiotherapy system using a motion phantom and radiochromic film.. Journal of applied clinical medical physics, 2017.
- Ginn JS, Agazaryan N, Cao M, Baharom U, Low DA, Yang Y, Gao Y, Hu P, Lee P, Lamb JM. Characterization of spatial distortion in a 0.35 T MRI-guided radiotherapy system.. Physics in medicine and biology, 2017.
- Kim W, Sharim J, Tenn S, Kaprealian T, Bordelon Y, Agazaryan N, Pouratian N. Diffusion tractography imaging-guided frameless linear accelerator stereotactic radiosurgical thalamotomy for tremor: case report.. Journal of neurosurgery, 2017.
- Chen AM, Cao M, Hsu S, Lamb J, Mikaeilian A, Yang Y, Agazaryan N, Low DA, Steinberg ML. Magnetic resonance imaging guided reirradiation of recurrent and second primary head and neck cancer.. Advances in radiation oncology, 2017.
- Shaverdian N, Yang Y, Hu P, Hart S, Sheng K, Lamb J, Cao M, Agazaryan N, Thomas D, Steinberg M, Low DA, Lee P. Feasibility evaluation of diffusion-weighted imaging using an integrated MRI-radiotherapy system for response assessment to neoadjuvant therapy in rectal cancer.. The British journal of radiology, 2017.
- Chow PE, Thomas DH, Agazaryan N, Cao M, Low DA, Yang Y, Steinberg ML, Lee P, Lamb JM. Technical Note: Dosimetric effects of couch position variability on treatment plan quality with an MRI-guided Co-60 radiation therapy machine.. Medical physics, 2016.
- Yang Y, Cao M, Sheng K, Gao Y, Chen A, Kamrava M, Lee P, Agazaryan N, Lamb J, Thomas D, Low D, Hu P. Longitudinal diffusion MRI for treatment response assessment: Preliminary experience using an MRI-guided tri-cobalt 60 radiotherapy system.. Medical physics, 2016.
- Shaverdian N, Tenn S, Veruttipong D, Wang J, Hegde J, Lee C, Cao M, Agazaryan N, Steinberg M, Kupelian P, Lee P. The significance of PTV dose coverage on cancer control outcomes in early stage non-small cell lung cancer patients treated with highly ablative stereotactic body radiation therapy.. The British journal of radiology, 2016.
- Merna C, Rwigema JC, Cao M, Wang PC, Kishan AU, Michailian A, Lamb J, Sheng K, Agazaryan N, Low DA, Kupelian P, Steinberg ML, Lee P. A treatment planning comparison between modulated tri-cobalt-60 teletherapy and linear accelerator-based stereotactic body radiotherapy for central early-stage non-small cell lung cancer.. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 2016.
- Yang Y, Cao M, Kaprealian T, Sheng K, Gao Y, Han F, Gomez C, Santhanam A, Tenn S, Agazaryan N, Low DA, Hu P. Accuracy of UTE-MRI-based patient setup for brain cancer radiation therapy.. Medical physics, 2016.
- Tsui I, Beardsley RM, McCannel TA, Oliver SC, Chun MW, Lee SP, Chow PE, Agazaryan N, Yu F, Straatsma BR. Visual Acuity, Contrast Sensitivity and Color Vision Three Years After Iodine-125 Brachytherapy for Choroidal and Ciliary Body Melanoma.. The open ophthalmology journal, 2015.
- Mehta N, Selch M, Wang PC, Federman N, Lee JM, Eilber FC, Chmielowski B, Agazaryan N, Steinberg M, Lee P. Safety and efficacy of stereotactic body radiation therapy in the treatment of pulmonary metastases from high grade sarcoma.. Sarcoma, 2013.
- Lamb JM, Agazaryan N, Low DA. Automated patient identification and localization error detection using 2-dimensional to 3-dimensional registration of kilovoltage x-ray setup images.. International journal of radiation oncology, biology, physics, 2013.
- De Los Santos J, Popple R, Agazaryan N, Bayouth JE, Bissonnette JP, Bucci MK, Dieterich S, Dong L, Forster KM, Indelicato D, Langen K, Lehmann J, Mayr N, Parsai I, Salter W, Tomblyn M, Yuh WT, Chetty IJ. Image guided radiation therapy (IGRT) technologies for radiation therapy localization and delivery.. International journal of radiation oncology, biology, physics, 2013.
- Lee P, Eppinga W, Lagerwaard F, Cloughesy T, Slotman B, Nghiemphu PL, Wang PC, Kupelian P, Agazaryan N, Demarco J, Selch MT, Steinberg M, Kang JJ. Evaluation of high ipsilateral subventricular zone radiation therapy dose in glioblastoma: a pooled analysis.. International journal of radiation oncology, biology, physics, 2013.
- Selch MT, Tenn S, Agazaryan N, Lee SP, Gorgulho A, De Salles AA. Image-guided linear accelerator-based spinal radiosurgery for hemangioblastoma.. Surgical neurology international, 2012.
- Chang MY, Kamrava M, Demanes DJ, Leu M, Agazaryan N, Lamb J, Moral JN, Almanzor R, McCannel TA. Intraoperative ultrasonography-guided positioning of iodine 125 plaque brachytherapy in the treatment of choroidal melanoma.. Ophthalmology, 2012.
- Mehta N, King CR, Agazaryan N, Steinberg M, Hua A, Lee P. Stereotactic body radiation therapy and 3-dimensional conformal radiotherapy for stage I non-small cell lung cancer: A pooled analysis of biological equivalent dose and local control.. Practical radiation oncology, 2011.
- Hauptman JS, Barkhoudarian G, Safaee M, Gorgulho A, Tenn S, Agazaryan N, Selch M, De Salles AA. Challenges in linear accelerator radiotherapy for chordomas and chondrosarcomas of the skull base: focus on complications.. International journal of radiation oncology, biology, physics, 2011.
- Smith ZA, Gorgulho AA, Bezrukiy N, McArthur D, Agazaryan N, Selch MT, De Salles AA. Dedicated linear accelerator radiosurgery for trigeminal neuralgia: a single-center experience in 179 patients with varied dose prescriptions and treatment plans.. International journal of radiation oncology, biology, physics, 2011.
- Kachikwu EL, Iwamoto KS, Liao YP, DeMarco JJ, Agazaryan N, Economou JS, McBride WH, Schaue D. Radiation enhances regulatory T cell representation.. International journal of radiation oncology, biology, physics, 2010.
- Xiao F, Gorgulho AA, Lin CS, Chen CH, Agazaryan N, Viñuela F, Selch MT, De Salles AA. Treatment of giant cerebral arteriovenous malformation: hypofractionated stereotactic radiation as the first stage.. Neurosurgery, 2010.
- Evers P, Lee PP, DeMarco J, Agazaryan N, Sayre JW, Selch M, Pajonk F. Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma.. BMC cancer, 2010.
- Agazaryan N. Monoscopic imaging for intrafraction motion management.. Journal of the American College of Radiology : JACR, 2010.
- Selch MT, Lin K, Agazaryan N, Tenn S, Gorgulho A, DeMarco JJ, DeSalles AA. Initial clinical experience with image-guided linear accelerator-based spinal radiosurgery for treatment of benign nerve sheath tumors.. Surgical neurology, 2009.
- Llacer J, Li S, Agazaryan N, Promberger C, Solberg TD. Non-coplanar automatic beam orientation selection in cranial IMRT: a practical methodology.. Physics in medicine and biology, 2009.
- Kesner AL, Lau VK, Speiser M, Hsueh WA, Agazaryan N, DeMarco JJ, Czernin J, Silverman DH. Time-course of effects of external beam radiation on [18F]FDG uptake in healthy tissue and bone marrow.. Journal of applied clinical medical physics, 2008.
- Agazaryan N, Tenn SE, Desalles AA, Selch MT. Image-guided radiosurgery for spinal tumors: methods, accuracy and patient intrafraction motion.. Physics in medicine and biology, 2008.
- Mattozo CA, De Salles AA, Klement IA, Gorgulho A, McArthur D, Ford JM, Agazaryan N, Kelly DF, Selch MT. Stereotactic radiation treatment for recurrent nonbenign meningiomas.. Journal of neurosurgery, 2007.
- Holzscheiter MH, Bassler N, Agazaryan N, Beyer G, Blackmore E, DeMarco JJ, Doser M, Durand RE, Hartley O, Iwamoto KS, Knudsen HV, Landua R, Maggiore C, McBride WH, Møller SP, Petersen J, Skarsgard LD, Smathers JB, Solberg TD, Uggerhøj UI, Vranjes S, Withers HR, Wong M, Wouters BG. The biological effectiveness of antiproton irradiation.. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006.
- Gorgulho A, De Salles AA, McArthur D, Agazaryan N, Medin P, Solberg T, Mattozo C, Ford J, Lee S, Selch MT. Brainstem and trigeminal nerve changes after radiosurgery for trigeminal pain.. Surgical neurology, 2006.
- Solberg TD, Agazaryan N, Goss BW, Dahlbom M, Lee SP. A feasibility study of 18F-fluorodeoxyglucose positron emission tomography targeting and simultaneous integrated boost for intensity-modulated radiosurgery and radiotherapy.. Journal of neurosurgery, 2004.
- Agazaryan N, Ullrich W, Lee SP, Solberg TD. A methodology for verification of radiotherapy dose calculation.. Journal of neurosurgery, 2004.
- De Salles AA, Pedroso AG, Medin P, Agazaryan N, Solberg T, Cabatan-Awang C, Espinosa DM, Ford J, Selch MT. Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy.. Journal of neurosurgery, 2004.
- Selch MT, Pedroso A, Lee SP, Solberg TD, Agazaryan N, Cabatan-Awang C, DeSalles AA. Stereotactic radiotherapy for the treatment of acoustic neuromas.. Journal of neurosurgery, 2004.
- Llacer J, Agazaryan N, Solberg TD, Promberger C. Degeneracy, frequency response and filtering in IMRT optimization.. Physics in medicine and biology, 2004.
- Agazaryan N, Solberg TD. Segmental and dynamic intensity-modulated radiotherapy delivery techniques for micro-multileaf collimator.. Medical physics, 2003.
- Hugo GD, Agazaryan N, Solberg TD. The effects of tumor motion on planning and delivery of respiratory-gated IMRT.. Medical physics, 2003.
- DeMarco JJ, Solberg TD, Agazaryan N. A seed specific dose kernel method for low-energy brachytherapy dosimetry.. Journal of applied clinical medical physics, 2003.
- Agazaryan N, Solberg TD, DeMarco JJ. Patient specific quality assurance for the delivery of intensity modulated radiotherapy.. Journal of applied clinical medical physics, 2003.
- Hugo GD, Agazaryan N, Solberg TD. An evaluation of gating window size, delivery method, and composite field dosimetry of respiratory-gated IMRT.. Medical physics, 2002.