Publications

1. Maier I, Ruegger PM, Deutschmann J, Helbich TH, Pietschmann P, Schiestl RH, Borneman J. Particle Radiation Side-Effects: Intestinal Microbiota Composition Shapes Interferon-γ-Induced Osteo-Immunogenicity.. Radiation research, 2022.
2. Maier I, Schiestl RH, Kontaxis G. Cyanovirin-N Binds Viral Envelope Proteins at the Low-Affinity Carbohydrate Binding Site without Direct Virus Neutralization Ability.. Molecules (Basel, Switzerland), 2021.
3. Maier I, Liu J, Ruegger PM, Deutschmann J, Patsch JM, Helbich TH, Borneman J, Schiestl RH. Intestinal bacterial indicator phylotypes associate with impaired DNA double-stranded break sensors but augmented skeletal bone micro-structure.. Carcinogenesis, 2020.
4. Schilling PE, Kontaxis G, Dragosits M, Schiestl RH, Becker CFW, Maier I. Mannosylated hemagglutinin peptides bind cyanovirin-N independent of disulfide-bonds in complementary binding sites.. RSC advances, 2020.
5. Davoren MJ, Liu J, Castellanos J, Rodríguez-Malavé NI, Schiestl RH. A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period.. Gut microbes, 2018.
6. Carroll JE, Van Dyk K, Bower JE, Scuric Z, Petersen L, Schiestl R, Irwin MR, Ganz PA. Cognitive performance in survivors of breast cancer and markers of biological aging.. Cancer, 2018.
7. Westbrook AM, Szakmary A, Schiestl RH. Retraction Note to: Mouse models of intestinal inflammation and cancer.. Archives of toxicology, 2018.
8. Davoren MJ, Schiestl RH. Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research.. Carcinogenesis, 2018.
9. Scuric Z, Carroll JE, Bower JE, Ramos-Perlberg S, Petersen L, Esquivel S, Hogan M, Chapman AM, Irwin MR, Breen EC, Ganz PA, Schiestl R. Biomarkers of aging associated with past treatments in breast cancer survivors.. NPJ breast cancer, 2017.
10. Böhmdorfer M, Szakmary A, Schiestl RH, Vaquero J, Riha J, Brenner S, Thalhammer T, Szekeres T, Jäger W. Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice.. Nutrients, 2017.
11. Wang W, Org T, Montel-Hagen A, Pioli PD, Duan D, Israely E, Malkin D, Su T, Flach J, Kurdistani SK, Schiestl RH, Mikkola HK. MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis.. Nature communications, 2016.
12. Westbrook AM, Szakmary A, Schiestl RH. Mouse models of intestinal inflammation and cancer.. Archives of toxicology, 2016.
13. Rivina L, Davoren MJ, Schiestl RH. Mouse models for radiation-induced cancers.. Mutagenesis, 2016.
14. Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ, Schiestl RH. Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis.. PloS one, 2016.
15. Galli A, Chan CY, Parfenova L, Cervelli T, Schiestl RH. Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.. Mutagenesis, 2015.
16. Maier I, Schiestl RH. Evidence from Animal Models: Is a Restricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury?. Radiation research, 2015.
17. Pai MY, Lomenick B, Hwang H, Schiestl R, McBride W, Loo JA, Huang J. Drug affinity responsive target stability (DARTS) for small-molecule target identification.. Methods in molecular biology (Clifton, N.J.), 2015.
18. Chapmana AM, Malkin DJ, Camacho J, Schiestl RH. IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood.. Mutation research, 2014.
19. Yamamoto ML, Schiestl RH. Lymphoma caused by intestinal microbiota.. International journal of environmental research and public health, 2014.
20. Rivina L, Davoren M, Schiestl RH. Radiation-induced myeloid leukemia in murine models.. Human genomics, 2014.
21. Yamamoto ML, Schiestl RH. Intestinal microbiome and lymphoma development.. Cancer journal (Sudbury, Mass.), 2014.
22. Maier I, Berry DM, Schiestl RH. Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons.. Radiation research, 2014.
23. Yamamoto ML, Maier I, Dang AT, Berry D, Liu J, Ruegger PM, Yang JI, Soto PA, Presley LL, Reliene R, Westbrook AM, Wei B, Loy A, Chang C, Braun J, Borneman J, Schiestl RH. Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity.. Cancer research, 2013.
24. Yamamoto ML, Chapman AM, Schiestl RH. Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells.. Mutation research, 2013.
25. Rivina L, Schiestl R. Mouse models of radiation-induced cancers.. Advances in genetics, 2013.
26. Rivina L, Schiestl R. Mouse models for efficacy testing of agents against radiation carcinogenesis—a literature review.. International journal of environmental research and public health, 2012.
27. Cabeza-Arvelaiz Y, Schiestl RH. Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.. PloS one, 2012.
28. Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF, Schiestl RH. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons.. Molecular neurodegeneration, 2011.
29. Sobol Z, Schiestl RH. Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity.. Environmental and molecular mutagenesis, 2011.
30. Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow.. Experimental hematology, 2011.
31. Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH. The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity.. Mutagenesis, 2011.
32. Westbrook AM, Wei B, Braun J, Schiestl RH. Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice.. International journal of cancer, 2011.
33. Aubrecht J, Goad ME, Czopik AK, Lerner CP, Johnson KA, Simpson EM, Schiestl RH. A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro.. Drug and chemical toxicology, 2011.
34. Chan CY, Zhu J, Schiestl RH. Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae.. Molecular genetics and genomics : MGG, 2011.
35. Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH. High throughput screening of small molecule libraries for modifiers of radiation responses.. International journal of radiation biology, 2011.
36. Reliene R, Yamamoto ML, Rao PN, Schiestl RH. Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.. Cancer research, 2010.
37. Yamamoto ML, Hafer K, Reliene R, Fleming S, Kelly O, Hacke K, Schiestl RH. Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice.. Radiation research, 2010.
38. Hafer K, Rivina Y, Schiestl RH. Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version.. Radiation research, 2010.
39. Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. New and emerging technologies for genetic toxicity testing.. Environmental and molecular mutagenesis, 2010.
40. Friedl AA, Kiechle M, Maxeiner HG, Schiestl RH, Eckardt-Schupp F. Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae.. Molecular genetics and genomics : MGG, 2010.
41. Walter MA, Hildebrandt IJ, Hacke K, Kesner AL, Kelly O, Lawson GW, Phelps ME, Czernin J, Weber WA, Schiestl RH. Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010.
42. Hafer K, Rivina L, Schiestl RH. Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae.. Radiation research, 2010.
43. Westbrook AM, Szakmary A, Schiestl RH. Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.. Mutation research, 2010.
44. Westbrook AM, Schiestl RH. Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.. Cancer research, 2010.
45. Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH. Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice.. Cancer research, 2009.
46. Galli A, Hafer K, Cervelli T, Schiestl RH. The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent.. Journal of biomedicine & biotechnology, 2009.
47. Westbrook AM, Wei B, Braun J, Schiestl RH. More damaging than we think: systemic effects of intestinal inflammation.. Cell cycle (Georgetown, Tex.), 2009.
48. Chan CY, Schiestl RH. Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae.. Radiation research, 2009.
49. Westbrook AM, Wei B, Braun J, Schiestl RH. Intestinal mucosal inflammation leads to systemic genotoxicity in mice.. Cancer research, 2009.
50. Scuric Z, Chan CY, Hafer K, Schiestl RH. Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells.. Radiation research, 2009.
51. Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH. N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals.. Mutation research, 2009.
52. Hafer K, Schiestl RH. Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species.. Radiation research, 2008.
53. Chan CY, Galli A, Schiestl RH. Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae.. DNA repair, 2008.
54. Yamamoto ML, Reliene R, Oshima J, Schiestl RH. Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.. Mutation research, 2008.
55. Reliene R, Schiestl RH. Experimental antioxidant therapy in ataxia telangiectasia.. Clinical medicine. Oncology, 2008.
56. Hafer K, Konishi T, Schiestl RH. Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method.. Radiation research, 2008.
57. Hafer K, Iwamoto KS, Schiestl RH. Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations.. Radiation research, 2008.
58. Chen X, Watkins R, Delot E, Reliene R, Schiestl RH, Burgoyne PS, Arnold AP. Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes.. Developmental neurobiology, 2008.
59. Rodriguez CE, Sobol Z, Schiestl RH. 9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae.. Toxicology in vitro : an international journal published in association with BIBRA, 2007.
60. Sobol Z, Cook NM, Schiestl RH. HNO induces DNA deletions in the yeast S. cerevisiae.. Mutation research, 2007.
61. Reliene R, Fleming SM, Chesselet MF, Schiestl RH. Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007.
62. Hafer K, Iwamoto KS, Iwamoto KK, Scuric Z, Schiestl RH. Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair.. Radiation research, 2007.
63. Chan CY, Kiechle M, Manivasakam P, Schiestl RH. Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae.. Nucleic acids research, 2007.
64. Hontzeas N, Hafer K, Schiestl RH. Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries.. Mutation research, 2007.
65. Ku WW, Aubrecht J, Mauthe RJ, Schiestl RH, Fornace AJ. Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment.. Toxicological sciences : an official journal of the Society of Toxicology, 2007.
66. Reliene R, Schiestl RH. Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice.. The Journal of nutrition, 2007.
67. Gietz RD, Schiestl RH. Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method.. Nature protocols, 2007.
68. Gietz RD, Schiestl RH. High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method.. Nature protocols, 2007.
69. Reliene R, Bishop AJ, Schiestl RH. Involvement of homologous recombination in carcinogenesis.. Advances in genetics, 2007.
70. Gietz RD, Schiestl RH. Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method.. Nature protocols, 2007.
71. Gietz RD, Schiestl RH. Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method.. Nature protocols, 2007.
72. Gietz RD, Schiestl RH. Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method.. Nature protocols, 2007.
73. Ohnishi K, Scuric Z, Yau D, Schiestl RH, Okamoto N, Takahashi A, Ohnishi T. Heat-induced phosphorylation of NBS1 in human skin fibroblast cells.. Journal of cellular biochemistry, 2006.
74. Ohnishi K, Scuric Z, Schiestl RH, Okamoto N, Takahashi A, Ohnishi T. siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status.. Radiation research, 2006.
75. Reliene R, Goad ME, Schiestl RH. Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine.. DNA repair, 2006.
76. Reliene R, Schiestl RH. Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice.. DNA repair, 2006.
77. Hafer K, Scuric Z, Iwamoto KS, Schiestl RH. Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution.. Radiation research, 2006.
78. Reliene R, Schiestl RH. Differences in animal housing facilities and diet may affect study outcomes-a plea for inclusion of such information in publications.. DNA repair, 2006.
79. Kirpnick-Sobol Z, Reliene R, Schiestl RH. Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice.. Cancer research, 2006.
80. Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients.. DNA repair, 2005.
81. Reliene R, Schiestl RH. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice.. Carcinogenesis, 2005.
82. Sommers CH, Schiestl RH. Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae.. Mutation research, 2005.
83. Kirpnick Z, Homiski M, Rubitski E, Repnevskaya M, Howlett N, Aubrecht J, Schiestl RH. Yeast DEL assay detects clastogens.. Mutation research, 2005.
84. Reliene R, Hlavacova A, Mahadevan B, Baird WM, Schiestl RH. Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice.. Mutation research, 2005.
85. Stone HB, Moulder JE, Coleman CN, Ang KK, Anscher MS, Barcellos-Hoff MH, Dynan WS, Fike JR, Grdina DJ, Greenberger JS, Hauer-Jensen M, Hill RP, Kolesnick RN, Macvittie TJ, Marks C, McBride WH, Metting N, Pellmar T, Purucker M, Robbins ME, Schiestl RH, Seed TM, Tomaszewski JE, Travis EL, Wallner PE, Wolpert M, Zaharevitz D. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003.. Radiation research, 2004.
86. Egorov AI, Howlett NG, Schiestl RH. Mutagen X and chlorinated tap water are recombinagenic in yeast.. Mutation research, 2004.
87. Rugo RE, Schiestl RH. Increases in oxidative stress in the progeny of X-irradiated cells.. Radiation research, 2004.
88. Reliene R, Fischer E, Schiestl RH. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice.. Cancer research, 2004.
89. Sommers CH, Schiestl RH. 2-Dodecylcyclobutanone does not induce mutations in the Salmonella mutagenicity test or intrachromosomal recombination in Saccharomyces cerevisiae.. Journal of food protection, 2004.
90. Reliene R, Bishop AJ, Li G, Schiestl RH. Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice.. DNA repair, 2004.
91. Howlett NG, Schiestl RH. Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae.. DNA repair, 2004.
92. Brennan RJ, Schiestl RH. Detecting carcinogens with the yeast DEL assay.. Methods in molecular biology (Clifton, N.J.), 2004.
93. Reliene R, Bishop AJ, Aubrecht J, Schiestl RH. In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer.. Methods in molecular biology (Clifton, N.J.), 2004.
94. Reliene R, Schiestl RH. Mouse models for induced genetic instability at endogenous loci.. Oncogene, 2003.
95. Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace AJ, Schiestl RH. Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development.. Cancer research, 2003.
96. Chen L, Huang S, Lee L, Davalos A, Schiestl RH, Campisi J, Oshima J. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.. Aging cell, 2003.
97. Galli A, Cervelli T, Schiestl RH. Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae.. Genetics, 2003.
98. Bishop AJ, Schiestl RH. Role of homologous recombination in carcinogenesis.. Experimental and molecular pathology, 2003.
99. Kiechle M, Manivasakam P, Eckardt-Schupp F, Schiestl RH, Friedl AA. Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion.. Nucleic acids research, 2002.
100. Vonarx EJ, Howlett NG, Schiestl RH, Kunz BA. Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant.. Gene, 2002.
101. Oshima J, Huang S, Pae C, Campisi J, Schiestl RH. Lack of WRN results in extensive deletion at nonhomologous joining ends.. Cancer research, 2002.
102. Wiesmüller L, Ford JM, Schiestl RH. DNA Damage, Repair, and Diseases.. Journal of biomedicine & biotechnology, 2002.
103. Bishop AJ, Schiestl RH. Homologous Recombination and Its Role in Carcinogenesis.. Journal of biomedicine & biotechnology, 2002.