Publications

1. Guo X, Adelaja A, Singh A, Wollman R, Hoffmann A. Modeling heterogeneous signaling dynamics of macrophages reveals principles of information transmission in stimulus responses.. Nature communications, 2025.
2. Hemminger Z, Sanchez-Tam G, Ocampo H, Wang A, Underwood T, Xie F, Zhao Q, Song D, Li JJ, Dong H, Wollman R. Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains.. bioRxiv : the preprint server for biology, 2024.
3. Luecke S, Guo X, Sheu KM, Singh A, Lowe SC, Han M, Diaz J, Lopes F, Wollman R, Hoffmann A. Dynamical and combinatorial coding by MAPK p38 and NFκB in the inflammatory response of macrophages.. Molecular systems biology, 2024.
4. Wu X, Wollman R, MacLean AL. Single-cell Ca2+ parameter inference reveals how transcriptional states inform dynamic cell responses.. Journal of the Royal Society, Interface, 2023.
5. Fuxjager MJ, Ryder TB, Moody NM, Alfonso C, Balakrishnan CN, Barske J, Bosholn M, Boyle WA, Braun EL, Chiver I, Dakin R, Day LB, Driver R, Fusani L, Horton BM, Kimball RT, Lipshutz S, Mello CV, Miller ET, Webster MS, Wirthlin M, Wollman R, Moore IT, Schlinger BA. Systems biology as a framework to understand the physiological and endocrine bases of behavior and its evolution-From concepts to a case study in birds.. Hormones and behavior, 2023.
6. Stearns-Reider KM, Hicks MR, Hammond KG, Reynolds JC, Maity A, Kurmangaliyev YZ, Chin J, Stieg AZ, Geisse NA, Hohlbauch S, Kaemmer S, Schmitt LR, Pham TT, Yamauchi K, Novitch BG, Wollman R, Hansen KC, Pyle AD, Crosbie RH. Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis.. NPJ Regenerative medicine, 2023.
7. Maltz E, Wollman R. Quantifying the phenotypic information in mRNA abundance.. Molecular systems biology, 2022.
8. Lannan R, Maity A, Wollman R. Epigenetic fluctuations underlie gene expression timescales and variability.. Physiological genomics, 2022.
9. Song D, Li K, Hemminger Z, Wollman R, Li JJ. scPNMF: sparse gene encoding of single cells to facilitate gene selection for targeted gene profiling.. Bioinformatics (Oxford, England), 2021.
10. Littman R, Hemminger Z, Foreman R, Arneson D, Zhang G, Gómez-Pinilla F, Yang X, Wollman R. Joint cell segmentation and cell type annotation for spatial transcriptomics.. Molecular systems biology, 2021.
11. Oyler-Yaniv J, Oyler-Yaniv A, Maltz E, Wollman R. TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread.. Nature communications, 2021.
12. Nagle MP, Tam GS, Maltz E, Hemminger Z, Wollman R. Bridging scales: From cell biology to physiology using in situ single-cell technologies.. Cell systems, 2021.
13. Tang Y, Adelaja A, Ye FX, Deeds E, Wollman R, Hoffmann A. Quantifying information accumulation encoded in the dynamics of biochemical signaling.. Nature communications, 2021.
14. Oliver Metzig M, Tang Y, Mitchell S, Taylor B, Foreman R, Wollman R, Hoffmann A. An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions.. Molecular systems biology, 2020.
15. Zhang T, Foreman R, Wollman R. Identifying chromatin features that regulate gene expression distribution.. Scientific reports, 2020.
16. Maity A, Wollman R. Information transmission from NFkB signaling dynamics to gene expression.. PLoS computational biology, 2020.
17. Zhang T, Pilko A, Wollman R. Loci specific epigenetic drug sensitivity.. Nucleic acids research, 2020.
18. Gunne-Braden A, Sullivan A, Gharibi B, Sheriff RSM, Maity A, Wang YF, Edwards A, Jiang M, Howell M, Goldstone R, Wollman R, East P, Santos SDM. GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells.. Cell stem cell, 2020.
19. Foreman R, Wollman R. Mammalian gene expression variability is explained by underlying cell state.. Molecular systems biology, 2020.
20. Gan L, Seki A, Shen K, Iyer H, Han K, Hayer A, Wollman R, Ge X, Lin JR, Dey G, Talbot WS, Meyer T. The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity.. Nature cell biology, 2019.
21. Wollman R. Single-Molecule Threshold of HIV Fate Decision.. Biophysical journal, 2017.
22. Handly LN, Wollman R. Wound-induced Ca2+ wave propagates through a simple release and diffusion mechanism.. Molecular biology of the cell, 2017.
23. Haglund E, Pilko A, Wollman R, Jennings PA, Onuchic JN. Pierced Lasso Topology Controls Function in Leptin.. The journal of physical chemistry. B, 2017.
24. Yao J, Pilko A, Wollman R. Distinct cellular states determine calcium signaling response.. Molecular systems biology, 2016.
25. Handly LN, Yao J, Wollman R. Signal Transduction at the Single-Cell Level: Approaches to Study the Dynamic Nature of Signaling Networks.. Journal of molecular biology, 2016.
26. Handly LN, Pilko A, Wollman R. Paracrine communication maximizes cellular response fidelity in wound signaling.. eLife, 2015.
27. Ourthiague DR, Birnbaum H, Ortenlöf N, Vargas JD, Wollman R, Hoffmann A. Limited specificity of IRF3 and ISGF3 in the transcriptional innate-immune response to double-stranded RNA.. Journal of leukocyte biology, 2015.
28. Selimkhanov J, Taylor B, Yao J, Pilko A, Albeck J, Hoffmann A, Tsimring L, Wollman R. Systems biology. Accurate information transmission through dynamic biochemical signaling networks.. Science (New York, N.Y.), 2014.
29. Wollman R. Development. Counting the ways to decode dynamic signals.. Science (New York, N.Y.), 2014.
30. Civelekoglu-Scholey G, Tao L, Brust-Mascher I, Wollman R, Scholey JM. Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope.. The Journal of cell biology, 2010.
31. Wollman R, Civelekoglu-Scholey G, Scholey JM, Mogilner A. Reverse engineering of force integration during mitosis in the Drosophila embryo.. Molecular systems biology, 2008.
32. Wollman R, Stuurman N. High throughput microscopy: from raw images to discoveries.. Journal of cell science, 2007.
33. Goshima G, Wollman R, Goodwin SS, Zhang N, Scholey JM, Vale RD, Stuurman N. Genes required for mitotic spindle assembly in Drosophila S2 cells.. Science (New York, N.Y.), 2007.
34. Tao L, Mogilner A, Civelekoglu-Scholey G, Wollman R, Evans J, Stahlberg H, Scholey JM. A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays.. Current biology : CB, 2006.
35. Mogilner A, Wollman R, Civelekoglu-Scholey G, Scholey J. Modeling mitosis.. Trends in cell biology, 2006.
36. Green RA, Wollman R, Kaplan KB. APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment.. Molecular biology of the cell, 2005.
37. Gutman R, Berezin C, Wollman R, Rosenberg Y, Ben-Tal N. QuasiMotiFinder: protein annotation by searching for evolutionarily conserved motif-like patterns.. Nucleic acids research, 2005.