Samuel French

Samuel Wheeler French

HS Clinical Professor, Pathology and Laboratory Medicine, University of California Los Angeles

(213) 533-2283

Publications

  1. Jeyachandran AV, Zaiss AK, Chakravarty N, Singh S, Delgado Y, Paravastu R, Satheeshkumar N, Gerald E, Jeysankar A, Thomas J, Fuller L, Lee N, Taylor C, Joshi S, Parcells M, French SW, Date A, Bouhaddou M, Garcia G, Kumar A, Damoiseaux R, Arumugaswami V. Drug screen reveals new potent host-targeted antivirals against Mpox virus.. Research square, 2025.
  2. Shi Y, Huang M, Zhou W, Zhao Y, Zhao J, Zhong B, French SW, Tang X, Liu H. TGF-β/JNK axis mediates mitochondrial damage and macrophage cGAS-STING activation in liver Mallory-Denk body pathogenesis.. Journal of translational medicine, 2025.
  3. Nguyen T, Shin Y, Ruppa A, Krall AS, Pham J, Chen PC, Mirmohammadi H, Keshavarz P, Finn RS, Agopian VG, French SW, Christofk HR, Lu DSK, Raman SS, Chiang J. Galectin-1 modulates glycolysis through a GM1-galactose-dependent pathway to promote hyperthermia resistance in HCC.. Hepatology (Baltimore, Md.), 2025.
  4. Jeyachandran AV, Zaiss AK, Chakravarty N, Singh S, Delgado Y, Paravastu R, Satheeshkumar N, Gerald E, Jeysankar A, Thomas J, Fuller L, Lee N, Taylor C, Joshi S, Parcells M, French SW, Date A, Bouhaddou M, Garcia G, Kumar A, Damoiseaux R, Arumugaswami V. Drug screen reveals new potent host-targeted antivirals against Mpox virus.. bioRxiv : the preprint server for biology, 2025.
  5. Sun Y, Aliyari SR, Parvatiyar K, Wang L, Zhen A, Sun W, Han X, Zhang A, Kato E, Shi H, De Schutter E, McBride WH, French SW, Cheng G. STING directly interacts with PAR to promote apoptosis upon acute ionizing radiation-mediated DNA damage.. Cell death and differentiation, 2025.
  6. Fang Z, Zhong B, Shi Y, Zhou W, Huang M, French SW, Tang X, Liu H. Single-cell transcriptomic analysis reveals characteristic feature of macrophage reprogramming in liver Mallory-Denk bodies pathogenesis.. Journal of translational medicine, 2025.
  7. Garcia G, Chakravarty N, Paiola S, Urena E, Gyani P, Tse C, French SW, Danielpour M, Breunig JJ, Nathanson DA, Arumugaswami V. Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus.. Cells, 2023.
  8. Hui ST, Gong L, Swichkow C, Blencowe M, Kaminska D, Diamante G, Pan C, Dalsania M, French SW, Magyar CE, Pajukanta P, Pihlajamäki J, Boström KI, Yang X, Lusis AJ. Role of Matrix Gla Protein in Transforming Growth Factor-β Signaling and Nonalcoholic Steatohepatitis in Mice.. Cellular and molecular gastroenterology and hepatology, 2023.
  9. Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ. Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.. Proceedings of the National Academy of Sciences of the United States of America, 2023.
  10. Zarrabi M, Hamilton C, French SW, Federman N, Nowicki TS. Successful treatment of severe immune checkpoint inhibitor associated autoimmune hepatitis with basiliximab: a case report.. Frontiers in immunology, 2023.
  11. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.. Cell reports. Medicine, 2023.
  12. Yuen C, Yu T, French S, Marcus EA, Yeh J, Chiu H. Treatment of an Adolescent Female With Nonalcoholic Steatohepatitis-Related Cirrhosis With Liraglutide.. JPGN reports, 2023.
  13. Sun N, Zhang C, Lee YT, Tran BV, Wang J, Kim H, Lee J, Zhang RY, Wang JJ, Hu J, Zhang Z, Alsudaney MS, Hou KC, Tang H, Zhang TX, Liang IY, Zhou Z, Chen M, Yeh AH, Li W, Zhou XJ, Chang HR, Han SB, Sadeghi S, Finn RS, Saab S, Busuttil RW, Noureddin M, Ayoub WS, Kuo A, Sundaram V, Al-Ghaieb B, Palomique J, Kosari K, Kim IK, Todo T, Nissen NN, Tomasi ML, You S, Posadas EM, Wu JX, Wadehra M, Sim MS, Li Y, Wang HL, French SW, Lu SC, Wu L, Pei R, Liang L, Yang JD, Agopian VG, Tseng HR, Zhu Y. HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma.. Hepatology (Baltimore, Md.), 2023.
  14. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses.. bioRxiv : the preprint server for biology, 2023.
  15. Garcia G, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response.. PLoS biology, 2022.
  16. Murray KA, Hughes MP, Hu CJ, Sawaya MR, Salwinski L, Pan H, French SW, Seidler PM, Eisenberg DS. Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.. Nature structural & molecular biology, 2022.
  17. Alvarez M, Benhammou JN, Darci-Maher N, French SW, Han SB, Sinsheimer JS, Agopian VG, Pisegna JR, Pajukanta P. Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival.. Genome medicine, 2022.
  18. Garcia G, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V. Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response.. bioRxiv : the preprint server for biology, 2022.
  19. Mona CE, Benz MR, Hikmat F, Grogan TR, Lueckerath K, Razmaria A, Riahi R, Slavik R, Girgis MD, Carlucci G, Kelly KA, French SW, Czernin J, Dawson DW, Calais J. Correlation of 68Ga-FAPi-46 PET Biodistribution with FAP Expression by Immunohistochemistry in Patients with Solid Cancers: Interim Analysis of a Prospective Translational Exploratory Study.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021.
  20. Hui ST, Wang F, Stappenbeck F, French SW, Magyar CE, Parhami F, Lusis AJ. Oxy210, a novel inhibitor of hedgehog and TGF-β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice.. Endocrinology, diabetes & metabolism, 2021.
  21. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.. Nature communications, 2021.
  22. Zhong B, Dong J, Zhang R, He M, Zeng W, Pan J, He J, Tao A, Yang R, Fu B, French SW, Liu H. Altered regulation of LncRNA analysis of human alcoholic hepatitis with Mallory-Denk Bodies (MDBs) is revealed by RNA sequencing.. Experimental and molecular pathology, 2020.
  23. Tuominen I, Fuqua BK, Pan C, Renaud N, Wroblewski K, Civelek M, Clerkin K, Asaryan A, Haroutunian SG, Loureiro J, Borawski J, Roma G, Knehr J, Carbone W, French S, Parks BW, Hui ST, Mehrabian M, Magyar C, Cantor RM, Ukomadu C, Lusis AJ, Beaven SW. The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice.. Cellular and molecular gastroenterology and hepatology, 2020.
  24. Gebremariam T, Zhang L, Alkhazraji S, Gu Y, Youssef EG, Tong Z, Kish-Trier E, Bajji A, de Araujo CV, Rich B, French SW, Li DY, Mueller AL, Odelberg SJ, Zhu W, Ibrahim AS. Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection.. Antimicrobial agents and chemotherapy, 2020.
  25. Badr El-Din NK, Ali DA, Othman R, French SW, Ghoneum M. Chemopreventive role of arabinoxylan rice bran, MGN-3/Biobran, on liver carcinogenesis in rats.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020.
  26. Neuman MG, Seitz HK, French SW, Malnick S, Tsukamoto H, Cohen LB, Hoffman P, Tabakoff B, Fasullo M, Nagy LE, Tuma PL, Schnabl B, Mueller S, Groebner JL, Barbara FA, Yue J, Nikko A, Alejandro M, Brittany T, Edward V, Harrall K, Saba L, Mihai O. Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research.. Biomedicines, 2020.
  27. Garcia G, Paul S, Beshara S, Ramanujan VK, Ramaiah A, Nielsen-Saines K, Li MMH, French SW, Morizono K, Kumar A, Arumugaswami V. Hippo Signaling Pathway Has a Critical Role in Zika Virus Replication and in the Pathogenesis of Neuroinflammation.. The American journal of pathology, 2020.
  28. Asahina K, Balog S, Hwang E, Moon E, Wan E, Skrypek K, Chen Y, Fernandez J, Romo J, Yang Q, Lai K, French SW, Tsukamoto H. Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.. American journal of physiology. Gastrointestinal and liver physiology, 2019.
  29. Balog S, Li Y, Ogawa T, Miki T, Saito T, French SW, Asahina K. Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice.. Hepatology (Baltimore, Md.), 2019.
  30. Khachatoorian R, Micewicz ED, Micewicz A, French SW, Ruchala P. Optimization of 1,3-disubstituted urea-based inhibitors of Zika virus infection.. Bioorganic & medicinal chemistry letters, 2019.
  31. Singh S, Uppuluri P, Mamouei Z, Alqarihi A, Elhassan H, French S, Lockhart SR, Chiller T, Edwards JE, Ibrahim AS. The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.. PLoS pathogens, 2019.
  32. Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.. Science advances, 2019.
  33. Baik M, French B, Chen YC, Byers JT, Chen KT, French SW, Díaz B. Identification of invadopodia by TKS5 staining in human cancer lines and patient tumor samples.. MethodsX, 2019.
  34. Chen YC, Baik M, Byers JT, Chen KT, French SW, Díaz B. Experimental supporting data on TKS5 and Cortactin expression and localization in human pancreatic cancer cells and tumors.. Data in brief, 2018.
  35. Chen YC, Baik M, Byers JT, Chen KT, French SW, Díaz B. TKS5-positive invadopodia-like structures in human tumor surgical specimens.. Experimental and molecular pathology, 2018.
  36. Hui ST, Kurt Z, Tuominen I, Norheim F, C Davis R, Pan C, Dirks DL, Magyar CE, French SW, Chella Krishnan K, Sabir S, Campos-Pérez F, Méndez-Sánchez N, Macías-Kauffer L, León-Mimila P, Canizales-Quinteros S, Yang X, Beaven SW, Huertas-Vazquez A, Lusis AJ. The Genetic Architecture of Diet-Induced Hepatic Fibrosis in Mice.. Hepatology (Baltimore, Md.), 2018.
  37. Wu R, Murali R, Kabe Y, French SW, Chiang YM, Liu S, Sher L, Wang CC, Louie S, Tsukamoto H. Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor-Initiating Stem Cell-Like Cells Resistant to mTORC1 Inhibition.. Hepatology (Baltimore, Md.), 2018.
  38. Hu Y, French SW, Chau T, Liu HX, Sheng L, Wei F, Stondell J, Garcia JC, Du Y, Bowlus CL, Wan YY. RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018.
  39. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. HSP70 Copurifies with Zika Virus Particles.. Virology, 2018.
  40. Court CM, Hou S, Winograd P, Segel NH, Li QW, Zhu Y, Sadeghi S, Finn RS, Ganapathy E, Song M, French SW, Naini BV, Sho S, Kaldas FM, Busuttil RW, Tomlinson JS, Tseng HR, Agopian VG. A novel multimarker assay for the phenotypic profiling of circulating tumor cells in hepatocellular carcinoma.. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2018.
  41. Chang HH, Moro A, Chou CEN, Dawson DW, French S, Schmidt AI, Sinnett-Smith J, Hao F, Hines OJ, Eibl G, Rozengurt E. Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model.. Scientific reports, 2018.
  42. Byers JT, Qing X, Lo C, French SW, Ji P. Unilateral localized conjunctival amyloidosis in a patient with a history of contralateral orbit/eyelid lymphoma.. Experimental and molecular pathology, 2018.
  43. Khanova E, Wu R, Wang W, Yan R, Chen Y, French SW, Llorente C, Pan SQ, Yang Q, Li Y, Lazaro R, Ansong C, Smith RD, Bataller R, Morgan T, Schnabl B, Tsukamoto H. Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.. Hepatology (Baltimore, Md.), 2018.
  44. Lu JG, Nguyen L, Samadzadeh S, Masouminia M, Mendoza A, Sweeney O, Tillman B, Afifyan N, Morgan T, French BA, French SW. Expression of proteins upregulated in hepatocellular carcinoma in patients with alcoholic hepatitis (AH) compared to non-alcoholic steatohepatitis (NASH): An immunohistochemical analysis of candidate proteins.. Experimental and molecular pathology, 2018.
  45. Micewicz ED, Khachatoorian R, French SW, Ruchala P. Identification of novel small-molecule inhibitors of Zika virus infection.. Bioorganic & medicinal chemistry letters, 2017.
  46. Roth NC, Saberi B, Macklin J, Kanel G, French SW, Govindarajan S, Buzzanco AS, Stolz AA, Donovan JA, Kaplowitz N. Prediction of histologic alcoholic hepatitis based on clinical presentation limits the need for liver biopsy.. Hepatology communications, 2017.
  47. Qing X, Panosyan E, Yue C, Ji P, Gotesman M, French S, Cai J. Therapy-related myeloid neoplasm in an 18-year-old boy with B-lymphoblastic leukemia.. Experimental and molecular pathology, 2017.
  48. Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z, Gukovsky I, Gukovskaya AS. Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.. Gastroenterology, 2017.
  49. Lu JG, Farukhi MA, Mayeda D, French SW. Hepatocellular carcinoma with neuroendocrine differentiation: a case report.. Experimental and molecular pathology, 2017.
  50. Jia Y, Yee JK, Wang C, Nikolaenko L, Diaz-Arjonilla M, Cohen JN, French SW, Liu PY, Lue Y, Lee WP, Swerdloff RS. Testosterone protects high-fat/low-carbohydrate diet-induced nonalcoholic fatty liver disease in castrated male rats mainly via modulating endoplasmic reticulum stress.. American journal of physiology. Endocrinology and metabolism, 2017.
  51. Chang HH, Moro A, Takakura K, Su HY, Mo A, Nakanishi M, Waldron RT, French SW, Dawson DW, Hines OJ, Li G, Go VLW, Sinnett-Smith J, Pandol SJ, Lugea A, Gukovskaya AS, Duff MO, Rosenberg DW, Rozengurt E, Eibl G. Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice.. PloS one, 2017.
  52. Court CM, Harlander-Locke MP, Markovic D, French SW, Naini BV, Lu DS, Raman SS, Kaldas FM, Zarrinpar A, Farmer DG, Finn RS, Sadeghi S, Tomlinson JS, Busuttil RW, Agopian VG. Determination of hepatocellular carcinoma grade by needle biopsy is unreliable for liver transplant candidate selection.. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017.
  53. Lugea A, Gerloff A, Su HY, Xu Z, Go A, Hu C, French SW, Wilson JS, Apte MV, Waldron RT, Pandol SJ. The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells.. Gastroenterology, 2017.
  54. French SW. Change in nomenclature for the immunologic synapse from Troxis Necrosis to trogocytosis.. Experimental and molecular pathology, 2017.
  55. Matsushita N, Hassanein MT, Martinez-Clemente M, Lazaro R, French SW, Xie W, Lai K, Karin M, Tsukamoto H. Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1.. PloS one, 2017.
  56. Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M. Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis.. Human molecular genetics, 2017.
  57. Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY. Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.. The American journal of pathology, 2017.
  58. Sheng L, Jena PK, Liu HX, Kalanetra KM, Gonzalez FJ, French SW, Krishnan VV, Mills DA, Wan YY. Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation.. Scientific reports, 2017.
  59. Lai KKY, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Lai K, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H. Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.. Gastroenterology, 2017.
  60. Neuman MG, French SW, Zakhari S, Malnick S, Seitz HK, Cohen LB, Salaspuro M, Voinea-Griffin A, Barasch A, Kirpich IA, Thomes PG, Schrum LW, Donohue TM, Kharbanda KK, Cruz M, Opris M. Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage.. Experimental and molecular pathology, 2017.
  61. Koo J, Dawson DW, Dry S, French SW, Naini BV, Wang HL. Allograft biopsy findings in patients with small bowel transplantation.. Clinical transplantation, 2016.
  62. Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.. International journal of antimicrobial agents, 2016.
  63. Peng Y, Qing AC, Cai J, Yue C, French SW, Qing X. Lymphoma of the liver: Clinicopathological features of 19 patients.. Experimental and molecular pathology, 2016.
  64. Lua I, Li Y, Zagory JA, Wang KS, French SW, Sévigny J, Asahina K. Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.. Journal of hepatology, 2016.
  65. Khachatoorian R, French SW. Chaperones in hepatitis C virus infection.. World journal of hepatology, 2016.
  66. Lu NT, Liu NM, Vu JQ, Patel D, Cohn W, Capri J, Ziegler M, Patel N, Tramontano A, Williams R, Whitelegge J, French SW. Phospho-Network Analysis Identifies and Quantifies Hepatitis C Virus (HCV)-induced Hepatocellular Carcinoma (HCC) Proteins Regulating Viral-mediated Tumor Growth.. Cancer genomics & proteomics, 2016.
  67. Liu H, Zhang X, Wu J, French SW, He Z. New insights on the palate, lung, and nasal epithelium clone (PLUNC) proteins: Based on molecular and functional analysis of its homolog of YH1/SPLUNC1.. Experimental and molecular pathology, 2015.
  68. Lu NT, Crespi CM, Liu NM, Vu JQ, Ahmadieh Y, Wu S, Lin S, McClune A, Durazo F, Saab S, Han S, Neiman DC, Beaven S, French SW. A Phase I Dose Escalation Study Demonstrates Quercetin Safety and Explores Potential for Bioflavonoid Antivirals in Patients with Chronic Hepatitis C.. Phytotherapy research : PTR, 2015.
  69. Uthaya Kumar DB, Chen CL, Liu JC, Feldman DE, Sher LS, French S, DiNorcia J, French SW, Naini BV, Junrungsee S, Agopian VG, Zarrinpar A, Machida K. TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.. Gastroenterology, 2015.
  70. Ignatius Irudayam J, Contreras D, Spurka L, Ren S, Kanagavel V, Ramaiah A, Annamalai A, French SW, Klein AS, Funari V, Arumugaswami V. Profile of Inflammation-associated genes during Hepatic Differentiation of Human Pluripotent Stem Cells.. Data in brief, 2015.
  71. Mareninova OA, Sendler M, Malla SR, Yakubov I, French SW, Tokhtaeva E, Vagin O, Oorschot V, Lüllmann-Rauch R, Blanz J, Dawson D, Klumperman J, Lerch MM, Mayerle J, Gukovsky I, Gukovskaya AS. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis.. Cellular and molecular gastroenterology and hepatology, 2015.
  72. Neuman MG, Malnick S, Maor Y, Nanau RM, Melzer E, Ferenci P, Seitz HK, Mueller S, Mell H, Samuel D, Cohen LB, Kharbanda KK, Osna NA, Ganesan M, Thompson KJ, McKillop IH, Bautista A, Bataller R, French SW. Alcoholic liver disease: Clinical and translational research.. Experimental and molecular pathology, 2015.
  73. Irudayam JI, Contreras D, Spurka L, Subramanian A, Allen J, Ren S, Kanagavel V, Nguyen Q, Ramaiah A, Ramamoorthy K, French SW, Klein AS, Funari V, Arumugaswami V. Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection.. Stem cell research, 2015.
  74. Liu M, Lin L, Gebremariam T, Luo G, Skory CD, French SW, Chou TF, Edwards JE, Ibrahim AS. Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine.. PLoS pathogens, 2015.
  75. Sullins VF, Traum PK, French SW, Wu BM, Dunn JC, Lee SL. A novel method of esophageal lengthening in a large animal model of long gap esophageal atresia.. Journal of pediatric surgery, 2015.
  76. Bardag-Gorce F, Oliva J, Wood A, Hoft R, Pan D, Thropay J, Makalinao A, French SW, Niihara Y. Carrier-free cultured autologous oral mucosa epithelial cell sheet (CAOMECS) for corneal epithelium reconstruction: a histological study.. The ocular surface, 2015.
  77. Lazaro R, Wu R, Lee S, Zhu NL, Chen CL, French SW, Xu J, Machida K, Tsukamoto H. Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice.. Hepatology (Baltimore, Md.), 2014.
  78. Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A.. Virology, 2014.
  79. Neuman MG, French SW, French BA, Seitz HK, Cohen LB, Mueller S, Osna NA, Kharbanda KK, Seth D, Bautista A, Thompson KJ, McKillop IH, Kirpich IA, McClain CJ, Bataller R, Nanau RM, Voiculescu M, Opris M, Shen H, Tillman B, Li J, Liu H, Thomes PG, Ganesan M, Malnick S. Alcoholic and non-alcoholic steatohepatitis.. Experimental and molecular pathology, 2014.
  80. Peng Y, French BA, Tillman B, Morgan TR, French SW. The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation.. Experimental and molecular pathology, 2014.
  81. Liu H, Li J, Tillman B, Morgan TR, French BA, French SW. TLR3/4 signaling is mediated via the NFκB-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory-Denk bodies.. Experimental and molecular pathology, 2014.
  82. Choi AH, French SW, Van Natta TL. Biopsy trauma dislodges thymocytes from a thymoma to fill regional lymph node sinusoids.. Experimental and molecular pathology, 2014.
  83. Kharbanda KK, Todero SL, Thomes PG, Orlicky DJ, Osna NA, French SW, Tuma DJ. Increased methylation demand exacerbates ethanol-induced liver injury.. Experimental and molecular pathology, 2014.
  84. Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, LaSalle JM, Halsted CH, Keen CL, Medici V. Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease.. International journal of molecular sciences, 2014.
  85. Enbom ET, Le MD, Oesterich L, Rutgers J, French SW. Mechanism of hepatotoxicity due to black cohosh (Cimicifuga racemosa): histological, immunohistochemical and electron microscopy analysis of two liver biopsies with clinical correlation.. Experimental and molecular pathology, 2014.
  86. Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.. Virology, 2014.
  87. Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease.. Epigenetics, 2013.
  88. Ibrahim AS, Luo G, Gebremariam T, Lee H, Schmidt CS, Hennessey JP, French SW, Yeaman MR, Filler SG, Edwards JE. NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response.. Vaccine, 2013.
  89. Chen CL, Tsukamoto H, Liu JC, Kashiwabara C, Feldman D, Sher L, Dooley S, French SW, Mishra L, Petrovic L, Jeong JH, Machida K. Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells.. The Journal of clinical investigation, 2013.
  90. Luo G, Gebremariam T, Lee H, French SW, Wiederhold NP, Patterson TF, Filler SG, Ibrahim AS. Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis.. Antimicrobial agents and chemotherapy, 2013.
  91. Chu D, Ren S, Hu S, Wang WG, Subramanian A, Contreras D, Kanagavel V, Chung E, Ko J, Amirtham Jacob Appadorai RS, Sinha S, Jalali Z, Hardy DW, French SW, Arumugaswami V. Systematic analysis of enhancer and critical cis-acting RNA elements in the protein-encoding region of the hepatitis C virus genome.. Journal of virology, 2013.
  92. Khachatoorian R, Dawson D, Maloney EM, Wang J, French BA, French SW, French SW. SAMe treatment prevents the ethanol-induced epigenetic alterations of genes in the Toll-like receptor pathway.. Experimental and molecular pathology, 2012.
  93. Khachatoorian R, Arumugaswami V, Raychaudhuri S, Yeh GK, Maloney EM, Wang J, Dasgupta A, French SW. Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle.. Virology, 2012.
  94. Nguyen Kovochich A, Arensman M, Lay AR, Rao NP, Donahue T, Li X, French SW, Dawson DW. HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma.. Cancer, 2012.
  95. Lu N, Khachatoorian R, French SW. Quercetin: bioflavonoids as part of interferon-free hepatitis C therapy?. Expert review of anti-infective therapy, 2012.
  96. Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW. A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production.. Hepatology (Baltimore, Md.), 2012.
  97. Brinckerhoff TZ, Bondada S, Lewis CE, French SW, DeUgarte DA. Metabolic effects of sleeve gastrectomy in female rat model of diet-induced obesity.. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2011.
  98. Luo G, Ibrahim AS, French SW, Edwards JE, Fu Y. Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis.. PloS one, 2011.
  99. Hong JC, Jones CM, Duffy JP, Petrowsky H, Farmer DG, French S, Finn R, Durazo FA, Saab S, Tong MJ, Hiatt JR, Busuttil RW. Comparative analysis of resection and liver transplantation for intrahepatic and hilar cholangiocarcinoma: a 24-year experience in a single center.. Archives of surgery (Chicago, Ill. : 1960), 2011.
  100. Xu J, Lai KKY, Verlinsky A, Lugea A, French SW, Cooper MP, Ji C, Tsukamoto H. Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK.. Journal of hepatology, 2011.
  101. Chen GC, Ramanathan VS, Law D, Funchain P, Chen GC, French S, Shlopov B, Eysselein V, Chung D, Reicher S, Pham BV. Acute liver injury induced by weight-loss herbal supplements.. World journal of hepatology, 2010.
  102. Ko KS, Tomasi ML, Iglesias-Ara A, French BA, French SW, Ramani K, Lozano JJ, Oh P, He L, Stiles BL, Li TW, Yang H, Martínez-Chantar ML, Mato JM, Lu SC. Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.. Hepatology (Baltimore, Md.), 2010.
  103. Wang G, Chen HW, Oktay Y, Zhang J, Allen EL, Smith GM, Fan KC, Hong JS, French SW, McCaffery JM, Lightowlers RN, Morse HC, Koehler CM, Teitell MA. PNPASE regulates RNA import into mitochondria.. Cell, 2010.
  104. Ibrahim AS, Gebremariam T, Lin L, Luo G, Husseiny MI, Skory CD, Fu Y, French SW, Edwards JE, Spellberg B. The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis.. Molecular microbiology, 2010.
  105. Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW. The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.. Hepatology (Baltimore, Md.), 2009.
  106. Xiong S, She H, Zhang AS, Wang J, Mkrtchyan H, Dynnyk A, Gordeuk VR, French SW, Enns CA, Tsukamoto H. Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis.. American journal of physiology. Gastrointestinal and liver physiology, 2008.
  107. Koh S, Bradley RF, French SW, Farmer DG, Cortina G. Congenital visceral myopathy with a predominantly hypertrophic pattern treated by multivisceral transplantation.. Human pathology, 2008.
  108. Kuraishy AI, French SW, Sherman M, Herling M, Jones D, Wall R, Teitell MA. TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation.. Proceedings of the National Academy of Sciences of the United States of America, 2007.
  109. Park JM, Kanaoka Y, Eguchi N, Aritake K, Grujic S, Materi AM, Buslon VS, Tippin BL, Kwong AM, Salido E, French SW, Urade Y, Lin HJ. Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.. Cancer research, 2007.
  110. Rainey RN, Glavin JD, Chen HW, French SW, Teitell MA, Koehler CM. A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space.. Molecular and cellular biology, 2006.
  111. Chen HW, Rainey RN, Balatoni CE, Dawson DW, Troke JJ, Wasiak S, Hong JS, McBride HM, Koehler CM, Teitell MA, French SW. Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis.. Molecular and cellular biology, 2006.
  112. French SW, Dawson DW, Chen HW, Rainey RN, Sievers SA, Balatoni CE, Wong L, Troke JJ, Nguyen MT, Koehler CM, Teitell MA. The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.. Cancer letters, 2006.
  113. Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, Tsukamoto H. Steatohepatitis induced by intragastric overfeeding in mice.. Hepatology (Baltimore, Md.), 2005.
  114. Hoyer KK, Herling M, Bagrintseva K, Dawson DW, French SW, Renard M, Weinger JG, Jones D, Teitell MA. T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation.. Journal of immunology (Baltimore, Md. : 1950), 2005.
  115. Chen C, Jing W, Gulati P, Vargas H, French SW. Melanocytic differentiation in a solid pseudopapillary tumor of the pancreas.. Journal of gastroenterology, 2004.
  116. Cho SH, Yao Z, Wang SW, Alban RF, Barbers RG, French SW, Oh CK. Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells.. Journal of immunology (Baltimore, Md. : 1950), 2003.
  117. Patrone L, Henson SE, Teodorovic J, Malone CS, French SW, Wall R, Teitell MA. Gene expression patterns in AIDS versus non-AIDS-related diffuse large B-cell lymphoma.. Experimental and molecular pathology, 2003.
  118. French SW, Malone CS, Shen RR, Renard M, Henson SE, Miner MD, Wall R, Teitell MA. Sp1 transactivation of the TCL1 oncogene.. The Journal of biological chemistry, 2002.
  119. Hoyer KK, French SW, Turner DE, Nguyen MT, Renard M, Malone CS, Knoetig S, Qi CF, Su TT, Cheroutre H, Wall R, Rawlings DJ, Morse HC, Teitell MA. Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.. Proceedings of the National Academy of Sciences of the United States of America, 2002.
  120. French SW, Hoyer KK, Shen RR, Teitell MA. Transdifferentiation and nuclear reprogramming in hematopoietic development and neoplasia.. Immunological reviews, 2002.
  121. French SW, Dawson DW, Miner MD, Doerr JR, Malone CS, Wall R, Teitell MA. DNA methylation profiling: a new tool for evaluating hematologic malignancies.. Clinical immunology (Orlando, Fla.), 2002.
  122. French SW, Shen RR, Koh PJ, Malone CS, Mallick P, Teitell MA. A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane.. Biochemistry, 2002.