Steven Andrew Barnes

Professor-in-Residence, Ophthalmology, University of California Los Angeles

Professor-in-Residence, Neurobiology, University of California Los Angeles

Education and Training

UC BerkeleyBA&PhD1985Neurobiology


  1. Fuller JT, Barnes S, Sadun LA, Ajmera P, Alexandrova AN, Sadun AA. Coenzyme Q10 trapping in mitochondrial complex I underlies Leber's hereditary optic neuropathy.. Proceedings of the National Academy of Sciences of the United States of America, 2023.
  2. Smith BJ, McHugh CF, Hirano AA, Brecha NC, Barnes S. Transient and Sustained Ganglion Cell Light Responses Are Differentially Modulated by Intrinsically Produced Reactive Oxygen Species Acting upon Specific Voltage-Gated Na+ Channel Isoforms.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023.
  3. Barnes S. Visual processing: When two synaptic strata are better than one.. Current biology : CB, 2022.
  4. Zhang X, Mandric I, Nguyen KH, Nguyen TTT, Pellegrini M, Grove JCR, Barnes S, Yang XJ. Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development.. Frontiers in cell and developmental biology, 2021.
  5. Hirano AA, Vuong HE, Kornmann HL, Schietroma C, Stella SL, Barnes S, Brecha NC. Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors.. Frontiers in cellular neuroscience, 2020.
  6. Grove JCR, Hirano AA, de Los Santos J, McHugh CF, Purohit S, Field GD, Brecha NC, Barnes S. Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.. PLoS biology, 2019.
  7. Hirano AA, Liu X, Brecha NC, Barnes S. Analysis of Feedback Signaling from Horizontal Cells to Photoreceptors in Mice.. Methods in molecular biology (Clifton, N.J.), 2018.
  8. Sun X, Hirano AA, Brecha NC, Barnes S. Calcium-activated BKCa channels govern dynamic membrane depolarizations of horizontal cells in rodent retina.. The Journal of physiology, 2017.
  9. Matynia A, Nguyen E, Sun X, Blixt FW, Parikh S, Kessler J, Pérez de Sevilla Müller L, Habib S, Kim P, Wang ZZ, Rodriguez A, Charles A, Nusinowitz S, Edvinsson L, Barnes S, Brecha NC, Gorin MB. Peripheral Sensory Neurons Expressing Melanopsin Respond to Light.. Frontiers in neural circuits, 2016.
  10. Liu X, Grove JC, Hirano AA, Brecha NC, Barnes S. Dopamine D1 receptor modulation of calcium channel currents in horizontal cells of mouse retina.. Journal of neurophysiology, 2016.
  11. Hirano AA, Liu X, Boulter J, Grove J, Pérez de Sevilla Müller L, Barnes S, Brecha NC. Targeted Deletion of Vesicular GABA Transporter from Retinal Horizontal Cells Eliminates Feedback Modulation of Photoreceptor Calcium Channels.. eNeuro, 2016.
  12. Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015.
  13. Sargoy A, Barnes S, Brecha NC, Pérez De Sevilla Müller L. Immunohistochemical and calcium imaging methods in wholemount rat retina.. Journal of visualized experiments : JoVE, 2014.
  14. Sargoy A, Sun X, Barnes S, Brecha NC. Differential calcium signaling mediated by voltage-gated calcium channels in rat retinal ganglion cells and their unmyelinated axons.. PloS one, 2014.
  15. Liu X, Hirano AA, Sun X, Brecha NC, Barnes S. Calcium channels in rat horizontal cells regulate feedback inhibition of photoreceptors through an unconventional GABA- and pH-sensitive mechanism.. The Journal of physiology, 2013.