Van Savage

Van Maurice Savage

Professor, Ecology And Evolutionary Biology, University of California Los Angeles

Professor, Computational Medicine, University of California Los Angeles


  1. Desai-Chowdhry P, Brummer AB, Savage VM. How axon and dendrite branching are guided by time, energy, and spatial constraints.. Scientific reports, 2022.
  2. Mira P, Lozano-Huntelman N, Johnson A, Savage VM, Yeh P. Evolution of antibiotic resistance impacts optimal temperature and growth rate in Escherichia coli and Staphylococcus epidermidis.. Journal of applied microbiology, 2022.
  3. Cruz-Loya M, Tekin E, Kang TM, Cardona N, Lozano-Huntelman N, Rodriguez-Verdugo A, Savage VM, Yeh PJ. Antibiotics Shift the Temperature Response Curve of Escherichia coli Growth.. mSystems, 2021.
  4. Lozano-Huntelman NA, Zhou A, Tekin E, Cruz-Loya M, Østman B, Boyd S, Savage VM, Yeh P. Hidden suppressive interactions are common in higher-order drug combinations.. iScience, 2021.
  5. Brummer AB, Lymperopoulos P, Shen J, Tekin E, Bentley LP, Buzzard V, Gray A, Oliveras I, Enquist BJ, Savage VM. Branching principles of animal and plant networks identified by combining extensive data, machine learning and modelling.. Journal of the Royal Society, Interface, 2021.
  6. Tekin E, Diamant ES, Cruz-Loya M, Enriquez V, Singh N, Savage VM, Yeh PJ. Using a newly introduced framework to measure ecological stressor interactions.. Ecology letters, 2020.
  7. Durán SM, Martin RE, Díaz S, Maitner BS, Malhi Y, Salinas N, Shenkin A, Silman MR, Wieczynski DJ, Asner GP, Bentley LP, Savage VM, Enquist BJ. Informing trait-based ecology by assessing remotely sensed functional diversity across a broad tropical temperature gradient.. Science advances, 2019.
  8. Wieczynski DJ, Boyle B, Buzzard V, Duran SM, Henderson AN, Hulshof CM, Kerkhoff AJ, McCarthy MC, Michaletz ST, Swenson NG, Asner GP, Bentley LP, Enquist BJ, Savage VM. Climate shapes and shifts functional biodiversity in forests worldwide.. Proceedings of the National Academy of Sciences of the United States of America, 2018.
  9. Tekin E, White C, Kang TM, Singh N, Cruz-Loya M, Damoiseaux R, Savage VM, Yeh PJ. Prevalence and patterns of higher-order drug interactions in Escherichia coli.. NPJ systems biology and applications, 2018.
  10. Cruz-Loya M, Kang TM, Lozano NA, Watanabe R, Tekin E, Damoiseaux R, Savage VM, Yeh PJ. Stressor interaction networks suggest antibiotic resistance co-opted from stress responses to temperature.. The ISME journal, 2018.
  11. Lee L, Savage VM, Yeh PJ. Intermediate Levels of Antibiotics May Increase Diversity of Colony Size Phenotype in Bacteria.. Computational and structural biotechnology journal, 2018.
  12. Beppler C, Tekin E, White C, Mao Z, Miller JH, Damoiseaux R, Savage VM, Yeh PJ. When more is less: Emergent suppressive interactions in three-drug combinations.. BMC microbiology, 2017.
  13. Brummer AB, Savage VM, Enquist BJ. A general model for metabolic scaling in self-similar asymmetric networks.. PLoS computational biology, 2017.
  14. Beppler C, Tekin E, Mao Z, White C, McDiarmid C, Vargas E, Miller JH, Savage VM, Yeh PJ. Uncovering emergent interactions in three-way combinations of stressors.. Journal of the Royal Society, Interface, 2016.
  15. Tekin E, Hunt D, Newberry MG, Savage VM. Do Vascular Networks Branch Optimally or Randomly across Spatial Scales?. PLoS computational biology, 2016.
  16. Hunt D, Savage VM. Asymmetries arising from the space-filling nature of vascular networks.. Physical review. E, 2016.
  17. Tekin E, Beppler C, White C, Mao Z, Savage VM, Yeh PJ. Enhanced identification of synergistic and antagonistic emergent interactions among three or more drugs.. Journal of the Royal Society, Interface, 2016.
  18. Newberry MG, Ennis DB, Savage VM. Testing Foundations of Biological Scaling Theory Using Automated Measurements of Vascular Networks.. PLoS computational biology, 2015.
  19. Vasseur DA, DeLong JP, Gilbert B, Greig HS, Harley CD, McCann KS, Savage V, Tunney TD, O'Connor MI. Increased temperature variation poses a greater risk to species than climate warming.. Proceedings. Biological sciences, 2014.
  20. Smith DD, Sperry JS, Enquist BJ, Savage VM, McCulloh KA, Bentley LP. Deviation from symmetrically self-similar branching in trees predicts altered hydraulics, mechanics, light interception and metabolic scaling.. The New phytologist, 2013.
  21. Savage VM, Herman AB, West GB, Leu K. Using Fractal Geometry and Universal Growth Curves as Diagnostics for Comparing Tumor Vasculature and Metabolic Rate With Healthy Tissue and for Predicting Responses to Drug Therapies.. Discrete and continuous dynamical systems. Series B, 2013.
  22. Dell AI, Pawar S, Savage VM. Temperature dependence of trophic interactions are driven by asymmetry of species responses and foraging strategy.. The Journal of animal ecology, 2013.
  23. Pawar S, Dell AI, Savage VM. Dimensionality of consumer search space drives trophic interaction strengths.. Nature, 2012.
  24. Amarasekare P, Savage V. A framework for elucidating the temperature dependence of fitness.. The American naturalist, 2011.
  25. Dell AI, Pawar S, Savage VM. Systematic variation in the temperature dependence of physiological and ecological traits.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
  26. Savage VM, Bentley LP, Enquist BJ, Sperry JS, Smith DD, Reich PB, von Allmen EI. Hydraulic trade-offs and space filling enable better predictions of vascular structure and function in plants.. Proceedings of the National Academy of Sciences of the United States of America, 2010.
  27. Savage VM, Enquist BJ, West GB. Comment on 'A critical understanding of the fractal model of metabolic scaling'.. The Journal of experimental biology, 2007.
  28. Price CA, Enquist BJ, Savage VM. A general model for allometric covariation in botanical form and function.. Proceedings of the National Academy of Sciences of the United States of America, 2007.
  29. Savage VM, White EP, Moses ME, Ernest SK, Enquist BJ, Charnov EL. Comment on "The illusion of invariant quantities in life histories".. Science (New York, N.Y.), 2006.
  30. West GB, Savage VM, Gillooly J, Enquist BJ, Woodruff WH, Brown JH. Physiology: Why does metabolic rate scale with body size?. Nature, 2003.