Hong Zhou

Professor, MIMG, University of California Los Angeles


Billing Address:
570 Westwood Plaza

Fax Number:

Laboratory Address:
254 BSRB, 615 Charles E. Young Dr. South
Los Angeles, CA 90095 6350 CNSI, 570 Westwood Plaza
Los Angeles, CA

Lab Number:

Office Address:
CNSI 5511C
570 Westwood Plaza
Los Angeles, CA 90095

Office Phone Number:

Dr. Zhou is a professor in the Department of Microbiology, Immunology and Molecular Genetics and the founding director of the UCLA Electron Imaging Center for Nanomachines.


Director, Electron Imaging Center for NanoMachines (EICN)
Member, Biochemistry, Biophysics & Structural Biology GPB Home Area, California NanoSystems Institute, Immunity, Microbes & Molecular Pathogenesis GPB Home Area

Research Interests

Professor Hong Zhou’s lab focuses on 3D structural studies of biological complexes using cryo-electron microscopy (cryoEM) and cryo-electron tomography (cryoET). These emerging methods are particularly suitable for structure determination of large molecular complexes, viruses, cellular machineries and bacterial cells. Recent efforts have focuses on developing and applying advanced cryoEM and cryoET techniques to visualize the dynamic processes of microbial infections and to decipher the mechanisms of fundamental biological processes. Dr. Zhou’s group is at the forefront in pushing the envelope of cryoEM reconstruction to atomic resolution.


Z. Hong Zhou, Ph. D. Professor Hong Zhou is a Professor in the Microbiology, Immunology, and Molecular Genetics department. His group studies the structures and functions of membrane proteins, protein-nucleic acid complexes and microbes using cryo electron microscopy (cryoEM) and cryo electron tomography (cryoET). He combines expertise in structural biology, microbiology, computational biology, and bioinformatics to address fundamental questions in biology. Recent efforts have focused on membrane protein structures and mechanisms of gene replication and transcription. Dr. Zhou was a Pew Scholar in the Biomedical Sciences, received numerous awards, including the Basil O’Connor Scholar Award, the Established Investigator Award of American Heart Association, the Burton award, and the KH Kuo Award of Distinguished Scientist.